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nonstructural_protein_P2
Euk-VirOnyong-nyong_virus
nonstructural_protein_P2__NP_740704__Onyong-nyong_virus__2169701
Identity
- Accession:
- NP_740704 ↗
- Protein ID:
- nonstructural_protein_P2
- Kingdom:
- euk
Quality
76.8
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Togaviridae›
Alphavirus›
Onyong-nyong_virus
TaxID: 2169701
Cluster
View cluster (15 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 181-311
Domain cluster:
rep: KX578043.1__AOT27930.1__X__00015__D87-267
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 58.4 | 1.40e-15 | 97.7% | 44.3% |
| PF13604.13 | AAA_30 | 34.5 | 2.50e-08 | 80.9% | 55.5% |
D2
high
residues 315-455
Domain cluster:
rep: IMGVR_UViG_3300009509_000914-3300009509-Ga0123573_1001185116__D490-580_655-727
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01707.23 best | Peptidase_C9 | 38.2 | 1.60e-09 | 19.1% | 13.4% |
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6jimB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.99 | 92.0 | 9.52e-01 | 94.3% | 100.0% |
| 4b3fX03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.88 | 74.0 | 6.44e-01 | 87.9% | 90.6% |
| 2xzlA05 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.86 | 73.0 | 6.22e-01 | 87.9% | 89.6% |
| 5rl9B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.85 | 72.0 | 7.11e-01 | 87.9% | 96.0% |
| 3vkwA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.85 | 76.0 | 7.47e-01 | 93.6% | 95.3% |
| 5eanA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.83 | 62.0 | 5.36e-01 | 77.3% | 92.3% |
| 3u4qA04 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.79 | 68.0 | 5.44e-01 | 91.5% | 91.3% |
| 6vsxA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 66.0 | 6.34e-01 | 88.7% | 96.2% |
| 3upuA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 59.0 | 6.16e-01 | 78.0% | 98.5% |
| 3jb9X01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.77 | 64.0 | 5.38e-01 | 87.9% | 80.8% |
| 3dmnA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.77 | 65.0 | 6.19e-01 | 88.7% | 93.8% |
| 1w36D03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 61.0 | 5.67e-01 | 85.8% | 98.3% |
| 3e1sA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 61.0 | 6.13e-01 | 85.8% | 92.9% |
| 1c4oA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 57.0 | 5.30e-01 | 83.7% | 96.0% |
| 3llmA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 51.0 | 4.34e-01 | 73.0% | 69.8% |
| 6x50A03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 56.0 | 4.91e-01 | 83.7% | 99.0% |
| 3b85A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 50.0 | 4.56e-01 | 73.0% | 77.0% |
| 2o0jA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 50.0 | 4.08e-01 | 73.8% | 61.0% |
| 2xgjB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 49.0 | 4.25e-01 | 76.6% | 97.7% |
| 1ej0A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.66 | 47.0 | 4.30e-01 | 72.3% | 95.0% |
| 2hyiC02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 54.0 | 5.12e-01 | 87.2% | 91.0% |
| 2r8rA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.65 | 46.0 | 4.08e-01 | 73.8% | 73.2% |
| 1sqsA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.64 | 45.0 | 3.82e-01 | 72.3% | 93.5% |
| 1cr2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 47.0 | 3.94e-01 | 76.6% | 86.2% |
| 2b3tA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 44.0 | 4.01e-01 | 70.9% | 85.4% |
| 3eucA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.63 | 44.0 | 3.92e-01 | 71.6% | 63.8% |
| 3wy7A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.63 | 44.0 | 3.69e-01 | 70.9% | 55.7% |
| 4a8jB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 45.0 | 3.92e-01 | 75.2% | 83.6% |
| 4dcmA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 42.0 | 4.00e-01 | 72.3% | 87.4% |
| 5bq5B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 42.0 | 3.87e-01 | 73.8% | 70.1% |
| 2qbyB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 42.0 | 3.94e-01 | 73.0% | 85.1% |
| 4p32B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 42.0 | 3.53e-01 | 73.0% | 84.3% |
| 7mdhA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 41.0 | 4.05e-01 | 72.3% | 87.6% |
| 2xheA02 | 3.40.50.1910 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 2 | 0.57 | 41.0 | 3.69e-01 | 75.2% | 84.3% |
| 5kwaA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 41.0 | 3.86e-01 | 74.5% | 71.0% |
| 1sxjE01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 40.0 | 3.88e-01 | 72.3% | 76.9% |
| 4pmxA00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.56 | 40.0 | 3.13e-01 | 72.3% | 82.4% |
| 3ejfA00 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.55 | 41.0 | 3.94e-01 | 78.7% | 88.0% |
| 2vf7B03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 44.0 | 3.55e-01 | 86.5% | 93.6% |
| 2acfB00 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.54 | 45.0 | 4.25e-01 | 90.8% | 94.2% |
| 2uyyA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 38.0 | 3.61e-01 | 70.9% | 61.5% |
| 1w4bA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 45.0 | 3.87e-01 | 90.8% | 81.9% |
| 1g6hA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 43.0 | 3.54e-01 | 87.9% | 92.5% |
| 1kcxA02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.52 | 38.0 | 2.93e-01 | 78.0% | 83.4% |
| 1lw7A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 37.0 | 3.64e-01 | 74.5% | 90.5% |
| 3loqA02 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.50 | 37.0 | 3.86e-01 | 77.3% | 90.7% |
| 2rbgA00 | 3.40.50.11100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 35.0 | 3.74e-01 | 72.3% | 84.7% |
ECOD (97)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4994530 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.88 | 75.0 | 4.98e-01 | 87.9% | 38.6% |
| 3428412 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.88 | 74.0 | 6.25e-01 | 87.9% | 89.5% |
| 3913640 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 74.0 | 6.11e-01 | 87.9% | 81.7% |
| 5024276 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 74.0 | 6.11e-01 | 87.9% | 87.0% |
| 3210977 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 74.0 | 6.31e-01 | 87.9% | 84.8% |
| 3222867 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 74.0 | 6.28e-01 | 88.7% | 89.3% |
| 4943170 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 73.0 | 6.46e-01 | 87.9% | 94.4% |
| 4028314 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 73.0 | 5.99e-01 | 87.9% | 90.4% |
| 4331804 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 73.0 | 6.45e-01 | 87.9% | 88.7% |
| 3525324 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.87 | 73.0 | 6.11e-01 | 87.9% | 79.1% |
| 3240292 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.24e-01 | 87.9% | 89.0% |
| 4943903 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 4.42e-01 | 87.2% | 27.3% |
| 3309083 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.00e-01 | 87.9% | 82.6% |
| 5015395 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 74.0 | 6.57e-01 | 88.7% | 94.1% |
| 3682625 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.86 | 73.0 | 4.71e-01 | 87.9% | 34.9% |
| 5005831 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.48e-01 | 87.9% | 94.7% |
| 3246401 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.28e-01 | 88.7% | 95.7% |
| 3930896 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.40e-01 | 87.9% | 93.8% |
| 3825238 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 5.97e-01 | 87.9% | 81.7% |
| 3265034 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.06e-01 | 87.9% | 81.8% |
| 3433486 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 72.0 | 6.11e-01 | 87.9% | 87.7% |
| 3696119 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 73.0 | 6.11e-01 | 87.9% | 92.7% |
| 3397089 | 2004.1.1.920 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, AAA_11, AAA_12 | 0.86 | 72.0 | 4.60e-01 | 87.9% | 29.8% |
| 3784726 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 72.0 | 6.00e-01 | 87.9% | 88.7% |
| 3617007 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 72.0 | 6.10e-01 | 87.9% | 84.1% |
| 4964651 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.86 | 72.0 | 6.59e-01 | 87.9% | 96.6% |
| 3838509 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 6.29e-01 | 87.9% | 93.5% |
| 3475074 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 73.0 | 5.89e-01 | 88.7% | 92.7% |
| 3786529 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 73.0 | 6.14e-01 | 90.1% | 91.6% |
| 3218209 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 5.49e-01 | 88.7% | 72.0% |
| 3535364 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 6.14e-01 | 87.9% | 87.1% |
| 2095415 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 6.86e-01 | 87.9% | 89.4% |
| 3936669 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 6.24e-01 | 88.7% | 89.3% |
| 2142440 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.85 | 72.0 | 6.19e-01 | 87.9% | 89.8% |
| 3389373 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 71.0 | 6.22e-01 | 87.9% | 86.0% |
| 3601477 | 2004.1.1.455 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 | 0.84 | 71.0 | 4.41e-01 | 87.9% | 57.4% |
| 3688101 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 71.0 | 6.01e-01 | 87.9% | 91.4% |
| 3605331 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 71.0 | 6.07e-01 | 88.7% | 87.4% |
| 3593770 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.84 | 71.0 | 6.06e-01 | 88.7% | 87.0% |
| 3408803 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 71.0 | 6.28e-01 | 88.7% | 91.8% |
| 3199673 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 71.0 | 5.73e-01 | 88.7% | 81.6% |
| 3266728 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.84 | 72.0 | 6.14e-01 | 89.4% | 91.0% |
| 3589167 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.84 | 65.0 | 6.56e-01 | 80.1% | 95.7% |
| 3731003 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.83 | 71.0 | 5.93e-01 | 88.7% | 87.6% |
| 3697444 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.83 | 70.0 | 5.69e-01 | 87.9% | 73.1% |
| 3391041 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.83 | 70.0 | 4.23e-01 | 87.9% | 23.3% |
| 3189268 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.83 | 61.0 | 4.95e-01 | 75.9% | 91.6% |
| 3549903 | 2004.1.1.1002 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11, AAA_12 | 0.83 | 70.0 | 4.30e-01 | 87.9% | 26.0% |
| 3265097 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.83 | 70.0 | 5.52e-01 | 88.7% | 75.2% |
| 3435461 | 2004.1.1.195 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C | 0.82 | 71.0 | 6.06e-01 | 89.4% | 92.4% |
| 3590301 | 2004.1.1.508 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C, UvrD_C_2 | 0.82 | 70.0 | 6.51e-01 | 88.7% | 95.9% |
| 3733470 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.82 | 68.0 | 6.03e-01 | 85.8% | 97.9% |
| 3432662 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.82 | 69.0 | 5.97e-01 | 87.9% | 89.3% |
| 3743179 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.82 | 70.0 | 4.19e-01 | 89.4% | 20.8% |
| 3972737 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.81 | 71.0 | 4.65e-01 | 91.5% | 40.9% |
| 3185870 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.81 | 61.0 | 5.26e-01 | 77.3% | 91.0% |
| 3926025 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.81 | 69.0 | 6.40e-01 | 88.7% | 92.9% |
| 3439817 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.80 | 68.0 | 5.83e-01 | 87.9% | 85.7% |
| 3174411 | 2004.1.1.455 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 | 0.80 | 67.0 | 4.14e-01 | 86.5% | 53.3% |
| 3423525 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.80 | 67.0 | 5.76e-01 | 87.9% | 89.5% |
| 3289802 | 284.1.1.0 ↗ | a+b two layers › FKBP-like › FKBP-like › FKBP-like | 0.79 | 65.0 | 4.26e-01 | 85.8% | 24.7% |
| 3760903 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.79 | 61.0 | 5.61e-01 | 80.1% | 97.8% |
| 3290749 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.79 | 64.0 | 6.24e-01 | 85.1% | 98.7% |
| 3985691 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.78 | 65.0 | 6.16e-01 | 87.2% | 93.3% |
| 1323360 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.77 | 64.0 | 6.85e-01 | 95.0% | 100.0% |
| 3603695 | 2004.1.1.496 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 | 0.77 | 63.0 | 5.67e-01 | 85.1% | 95.1% |
| 1230975 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.77 | 65.0 | 6.19e-01 | 88.7% | 93.8% |
| 3980676 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.77 | 65.0 | 5.50e-01 | 90.8% | 92.6% |
| 4429341 | 2004.1.1.496 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 | 0.76 | 62.0 | 5.66e-01 | 85.1% | 89.4% |
| 3970065 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.76 | 63.0 | 5.91e-01 | 85.8% | 96.4% |
| None | — | 0.74 | 62.0 | 4.05e-01 | 87.2% | 23.9% | |
| 3163822 | 2004.1.1.496 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 | 0.74 | 61.0 | 5.88e-01 | 85.1% | 96.1% |
| 3590487 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.74 | 60.0 | 6.02e-01 | 85.1% | 97.9% |
| None | — | 0.74 | 61.0 | 6.07e-01 | 85.8% | 98.6% | |
| 3278699 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.74 | 60.0 | 5.83e-01 | 85.1% | 77.4% |
| 3682367 | 2004.1.1.496 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 | 0.73 | 56.0 | 5.80e-01 | 80.1% | 98.5% |
| 3676955 | 2004.1.1.203 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 | 0.72 | 59.0 | 5.46e-01 | 85.1% | 91.3% |
| 3926523 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 59.0 | 5.56e-01 | 85.1% | 90.9% |
| 3372829 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 58.0 | 5.74e-01 | 83.0% | 99.3% |
| 3511279 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 59.0 | 5.20e-01 | 85.1% | 90.8% |
| 3807611 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 59.0 | 5.70e-01 | 85.1% | 90.3% |
| 3682236 | 2004.1.1.496 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 | 0.72 | 59.0 | 5.48e-01 | 85.1% | 94.1% |
| 3648251 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.71 | 58.0 | 4.94e-01 | 85.1% | 93.6% |
| 3671414 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.71 | 58.0 | 5.30e-01 | 85.1% | 97.2% |
| 3658525 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.71 | 56.0 | 5.69e-01 | 81.6% | 96.4% |
| 3305691 | 2004.1.1.298 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_Helicase | 0.71 | 58.0 | 5.63e-01 | 85.1% | 93.5% |
| 4098321 | 2004.1.1.494 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADDB_N, PF27467 | 0.71 | 60.0 | 4.17e-01 | 89.4% | 40.0% |
| 3683589 | 2004.1.1.135 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 | 0.71 | 58.0 | 4.08e-01 | 85.1% | 39.5% |
| 3286902 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.71 | 58.0 | 5.61e-01 | 85.1% | 92.9% |
| 3656784 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.71 | 58.0 | 5.28e-01 | 85.1% | 86.7% |
| None | — | 0.70 | 56.0 | 4.40e-01 | 82.3% | 58.1% | |
| 3680771 | 2004.1.1.135 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 | 0.70 | 57.0 | 4.60e-01 | 85.1% | 61.6% |
| 3242523 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.69 | 56.0 | 5.89e-01 | 85.1% | 94.6% |
| 3447945 | 2004.1.1.56 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC | 0.60 | 43.0 | 3.65e-01 | 74.5% | 54.2% |
| 3446357 | 2004.1.1.56 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC | 0.58 | 41.0 | 3.39e-01 | 73.0% | 54.0% |
| 3654445 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 41.0 | 3.40e-01 | 75.9% | 80.0% |
| 3442635 | 2004.1.1.56 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC | 0.54 | 44.0 | 4.08e-01 | 87.2% | 76.7% |
D3
high
residues 624-790
Domain cluster:
rep: IMGVR_UViG_3300009616_000257-3300009616-Ga0116111_100275611__D486-632
D4
medium
residues 1-81
D5
medium
residues 82-174
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20896.3 best | ToMV_Hel_N | 165.7 | 1.20e-48 | 100.0% | 58.9% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4z1xA02 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.64 | 31.0 | 2.69e-01 | 83.9% | 30.1% |
| 4ocqA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.58 | 39.0 | 2.94e-01 | 100.0% | 26.7% |
| 7qu8A01 | 2.60.220.50 | Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › | 0.50 | 44.0 | 3.46e-01 | 100.0% | 78.4% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2514718 | 3590.1.1.1 ↗ | a+b complex topology › Tomato mosaic virus helicase N-terminal domain › Tomato mosaic virus helicase N-terminal domain › Tomato mosaic virus helicase N-terminal domain › ToMV_Hel_N | 0.89 | 84.0 | 6.70e-01 | 100.0% | 56.3% |
| 4952768 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.59 | 44.0 | 3.17e-01 | 78.5% | 98.9% |
| 4983554 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.59 | 44.0 | 3.18e-01 | 78.5% | 98.5% |
| 5072708 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.57 | 42.0 | 3.01e-01 | 78.5% | 97.6% |
| 4593431 | 223.1.1.67 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › CHASE7 | 0.54 | 48.0 | 3.73e-01 | 100.0% | 95.7% |
| 4959210 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.52 | 39.0 | 2.91e-01 | 80.6% | 98.1% |
| 4937881 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.51 | 39.0 | 3.06e-01 | 82.8% | 59.6% |
| None | — | 0.51 | 44.0 | 3.12e-01 | 100.0% | 81.6% | |
| 3441457 | 3887.2.1.1 ↗ | a+b two layers › Yeast killer toxin-like › Antifungal protein ginkbilobin-2 › Antifungal protein ginkbilobin-2 › Stress-antifung | 0.50 | 40.0 | 3.55e-01 | 92.5% | 60.8% |
D6
medium
residues 468-511_537-554
D7
medium
residues 512-536_555-606
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01707.23 best | Peptidase_C9 | 93.0 | 2.80e-26 | 100.0% | 47.0% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3trkA01 | 3.90.70.110 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Alphavirus nsP2 protease domain | 0.91 | 84.0 | 6.76e-01 | 98.7% | 68.6% |
| 4gvbA00 | 3.30.70.440 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Killer toxin KP6 alpha-subunit | 0.56 | 36.0 | 3.65e-01 | 84.4% | 66.2% |