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nonstructural_protein

Euk-Vir

Thrush_coronavirus_HKU12-600

nonstructural_protein__YP_002308500__Thrush_coronavirus_HKU12-600__572290

Identity

Accession:
YP_002308500 ↗
Protein ID:
nonstructural_protein
Kingdom:
euk

Quality

90.9 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Deltacoronavirus› Thrush_coronavirus_HKU12-600

TaxID: 572290

Cluster

View cluster (14 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-87
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF27996.1 best NS6_deltaCoV 141.5 9.80e-42 100.0% 95.6%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kkeB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 41.0 3.44e-01 85.9% 38.2%
1pjrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 42.0 3.25e-01 72.9% 29.2%
4evsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 49.0 3.91e-01 87.1% 45.6%
3lmkA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 48.0 3.83e-01 87.1% 42.6%
3brsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 43.0 3.66e-01 85.9% 46.3%
3i45A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 48.0 3.77e-01 87.1% 41.1%
2oasA01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.60 38.0 3.05e-01 94.1% 30.9%
3uyiA01 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.59 46.0 3.19e-01 92.9% 24.2%
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.59 40.0 2.68e-01 74.1% 17.0%
4go1A02 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 41.0 2.99e-01 92.9% 25.9%
4c4oA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 38.0 3.34e-01 94.1% 44.6%
1htwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 39.0 3.25e-01 71.8% 65.2%
2cycA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 36.0 2.75e-01 71.8% 25.2%
2h6eA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 43.0 3.57e-01 97.6% 49.0%
4kq9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 44.0 3.37e-01 88.2% 56.5%
2ap9B00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.54 37.0 2.61e-01 71.8% 48.3%
1gg1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 46.0 3.09e-01 94.1% 30.7%
2f48A02 3.40.50.460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphofructokinase domain 0.54 41.0 3.25e-01 83.5% 38.8%
4nl4H03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 44.0 3.41e-01 100.0% 39.8%
3brqB02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 44.0 3.68e-01 89.4% 54.2%
3e3mA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 3.67e-01 90.6% 53.8%
2o20A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 42.0 3.61e-01 89.4% 54.0%
3c3kA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 3.70e-01 89.4% 55.1%
1jx6A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 47.0 3.82e-01 100.0% 53.6%
3k4hA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 42.0 3.61e-01 88.2% 53.5%
4azsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 41.0 3.11e-01 85.9% 69.9%
3qi7A02 3.40.50.11390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 36.0 2.99e-01 72.9% 58.7%
1xr4A02 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.52 42.0 3.02e-01 89.4% 29.7%
3bblA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 42.0 3.59e-01 89.4% 53.8%
3nl6B01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 42.0 3.18e-01 91.8% 35.4%
4eexA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 35.0 3.07e-01 89.4% 43.6%
5c5cA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 44.0 3.63e-01 100.0% 87.2%
3aptA00 3.20.20.220 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.51 39.0 2.80e-01 85.9% 38.7%
3huuC02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 37.0 3.27e-01 87.1% 49.6%
1nytA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 40.0 3.35e-01 95.3% 49.7%
1c4oA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 3.70e-01 100.0% 61.4%
1tjyA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 44.0 3.67e-01 100.0% 55.6%
7xg9A01 3.20.20.220 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.50 39.0 2.79e-01 85.9% 37.7%
5k8bA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 44.0 3.21e-01 100.0% 49.4%
1pfkA02 3.40.50.460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphofructokinase domain 0.50 42.0 3.77e-01 95.3% 99.2%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3614415 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.67 53.0 3.76e-01 87.1% 33.8%
3498991 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.63 42.0 2.92e-01 71.8% 20.7%
4124050 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.62 37.0 2.87e-01 71.8% 24.4%
3587036 2007.1.2.10 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.62 42.0 3.73e-01 91.8% 46.9%
4329821 2007.1.2.7 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › LppC 0.61 41.0 3.31e-01 87.1% 35.1%
3405581 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.61 48.0 3.92e-01 87.1% 48.5%
1814017 2007.1.2.11 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 0.61 45.0 3.84e-01 91.8% 48.9%
3907772 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.60 48.0 3.35e-01 87.1% 54.6%
4348037 2004.1.1.189 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_16 0.60 41.0 3.13e-01 71.8% 88.6%
4938116 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 42.0 2.63e-01 72.9% 40.9%
1546769 2007.1.2.11 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 0.59 43.0 3.72e-01 91.8% 48.9%
3960482 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 40.0 3.14e-01 71.8% 89.8%
5061676 2007.1.2.58 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Hydant_A_N 0.59 39.0 3.19e-01 71.8% 34.7%
3974852 2007.1.2.10 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.58 43.0 3.77e-01 87.1% 51.5%
3624128 2002.1.1.76 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DeoC 0.58 48.0 3.33e-01 94.1% 25.9%
2771044 2004.1.1.150 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DRMBL 0.58 40.0 3.37e-01 98.8% 41.5%
4991587 5104.1.1.0 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.57 44.0 3.91e-01 84.7% 67.7%
4093200 2007.1.2.7 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › LppC 0.57 41.0 3.69e-01 92.9% 51.5%
4983692 2007.1.2.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp 0.57 40.0 3.39e-01 83.5% 42.0%
5033715 301.6.1.0 ↗ a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like 0.57 37.0 3.59e-01 71.8% 57.0%
5067093 2007.1.1.15 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF2124 0.57 44.0 3.66e-01 84.7% 47.7%
3221108 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.57 44.0 3.54e-01 85.9% 69.7%
None — 0.54 43.0 2.81e-01 100.0% 18.5%
4981232 2003.1.7.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like 0.54 43.0 3.21e-01 89.4% 34.0%
4142504 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.53 44.0 3.34e-01 98.8% 37.1%
5033806 2003.1.7.9 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › CitF 0.53 42.0 3.09e-01 89.4% 30.8%
3602841 2004.1.1.66 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase_2 0.53 45.0 3.40e-01 96.5% 40.9%
5006637 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.53 46.0 3.77e-01 100.0% 63.0%
3518602 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.52 45.0 3.62e-01 98.8% 51.1%
1147798 2007.1.2.9 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › DUF3798 0.52 36.0 3.00e-01 72.9% 59.8%
5021943 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.52 43.0 3.23e-01 95.3% 81.7%
None — 0.52 44.0 3.40e-01 96.5% 43.5%
4955502 2004.1.1.1199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF499 0.51 43.0 3.10e-01 98.8% 49.5%
3513846 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 41.0 3.08e-01 90.6% 40.0%
4277449 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.50 43.0 3.03e-01 100.0% 41.0%