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nsp13

Euk-Vir

Canada_goose_coronavirus

nsp13__YP_009755921__Canada_goose_coronavirus__2569586

Identity

Accession:
YP_009755921 ↗
Protein ID:
nsp13
Kingdom:
euk

Quality

90.1 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Gammacoronavirus› Canada_goose_coronavirus

TaxID: 2569586

Cluster

View cluster (23 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-47_82-144
PDB
Domain cluster: rep: NSP13__YP_001941186__Turkey_coronavirus__11152__D2-47_82-145
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF20632.3 best CoV_NSP13_ZBD 87.2 1.20e-24 45.0% 51.6%
PF20633.3 CoV_NSP13_stalk 87.6 8.10e-25 44.0% 97.9%
D2 high residues 146-226
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20631.4 best CoV_NSP13_1B 143.6 2.40e-42 100.0% 98.8%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6oqrA01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.77 59.0 5.69e-01 98.8% 73.3%
2dpyA00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.74 61.0 3.81e-01 100.0% 17.1%
1fx0B01 2.40.10.170 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.71 60.0 6.09e-01 96.3% 94.9%
4b3fX02 2.40.30.270 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.69 62.0 5.86e-01 100.0% 99.0%
6mv2A02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.69 61.0 5.61e-01 100.0% 98.1%
3op1A02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.67 57.0 5.22e-01 97.5% 71.2%
2ijzA02 2.30.250.10 Mainly Beta › Roll › Aminopeptidase i, Domain 2 › Aminopeptidase i, Domain 2 0.67 57.0 5.22e-01 96.3% 98.1%
5tr9A01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.67 58.0 5.51e-01 97.5% 95.8%
3gwqA01 2.40.37.20 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › D-serine dehydratase-like domain 0.66 58.0 4.59e-01 100.0% 48.3%
1krhA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.66 58.0 5.49e-01 100.0% 97.9%
1ep3B01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.66 57.0 5.41e-01 98.8% 96.0%
5ylyA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.66 58.0 5.20e-01 98.8% 98.2%
2v31A01 2.40.30.180 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Ubiquitin-activating enzyme E1, FCCH domain 0.65 58.0 5.50e-01 100.0% 83.5%
2gpjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 57.0 5.38e-01 100.0% 96.0%
2xnjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 57.0 5.30e-01 100.0% 98.1%
2eixA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.64 56.0 5.18e-01 98.8% 96.2%
1vw3C01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.64 57.0 4.89e-01 100.0% 69.5%
4wqmA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.63 56.0 5.28e-01 100.0% 91.8%
1w96C04 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.63 45.0 3.16e-01 75.3% 77.7%
2r6hA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.63 55.0 4.63e-01 100.0% 97.9%
2xzlA02 2.40.30.230 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.63 54.0 5.47e-01 100.0% 98.7%
4lusB01 2.40.37.10 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › Lyase, Ornithine Decarboxylase; Chain A, domain 1 0.60 53.0 4.37e-01 100.0% 60.4%
1a9xA06 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.60 43.0 3.18e-01 75.3% 71.9%
3zpeA00 2.60.90.50 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › 0.59 52.0 4.39e-01 100.0% 60.1%
1kkeA02 2.60.90.20 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Virus attachment protein , globular domain 0.59 47.0 4.03e-01 91.4% 87.2%
4j27A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.58 44.0 4.30e-01 100.0% 74.2%
2cdoA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.58 46.0 3.92e-01 87.7% 84.8%
3lp8A03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.57 40.0 3.41e-01 75.3% 65.9%
3wnzA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.56 40.0 3.34e-01 75.3% 55.6%
4wz9A01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.56 48.0 3.66e-01 100.0% 42.1%
3zjyC00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 41.0 4.33e-01 100.0% 85.1%
2z04B03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.56 40.0 3.09e-01 75.3% 79.6%
4jcwA02 2.60.40.760 Mainly Beta › Sandwich › Immunoglobulin-like › Expansin, cellulose-binding-like domain 0.56 39.0 3.88e-01 95.1% 68.9%
1ehiA02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.54 41.0 3.38e-01 80.2% 65.3%
3utoB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 44.0 4.19e-01 100.0% 76.0%
3k5iA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.53 38.0 2.88e-01 75.3% 78.3%
1od3A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 43.0 3.70e-01 90.1% 87.0%
4odbA00 2.60.90.20 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Virus attachment protein , globular domain 0.52 45.0 3.66e-01 98.8% 58.0%
1e4eB01 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.52 39.0 3.21e-01 80.2% 59.6%
2j73A00 2.60.40.1110 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.47e-01 88.9% 59.2%
4d0qA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 40.0 3.30e-01 86.4% 85.7%
4icwA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 40.0 3.43e-01 87.7% 53.1%
2v72A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.50 43.0 3.66e-01 100.0% 57.7%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2770367 1.1.7.43 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › CoV_NSP13_1B 0.91 85.0 8.39e-01 98.8% 95.2%
3967745 1.1.7.17 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.78 63.0 6.53e-01 98.8% 94.7%
3419484 1.1.7.50 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › EF-G_D2 0.76 70.0 6.35e-01 100.0% 88.6%
3326611 1.1.7.19 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › GTP_EFTU_D2 0.75 69.0 6.16e-01 100.0% 84.5%
1790393 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.74 62.0 6.21e-01 100.0% 90.2%
3388311 1.1.7.100 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PGBA_N 0.74 65.0 6.39e-01 95.1% 97.6%
4010630 2004.1.1.10 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP-synt_ab 0.74 61.0 3.83e-01 100.0% 17.2%
3966724 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.73 66.0 6.29e-01 100.0% 100.0%
4319764 1.1.7.17 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.73 61.0 5.55e-01 100.0% 68.2%
4060133 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.72 64.0 6.22e-01 100.0% 94.4%
3247934 1.1.7.41 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › UPF1_1B_dom 0.72 63.0 6.05e-01 100.0% 97.9%
3975044 1.1.7.17 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.71 59.0 6.14e-01 100.0% 98.7%
4211588 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.71 62.0 3.89e-01 100.0% 23.4%
4024940 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.70 62.0 4.89e-01 100.0% 95.3%
4963598 1.1.7.150 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF26503 0.69 54.0 5.56e-01 84.0% 89.3%
4939469 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.69 62.0 5.91e-01 100.0% 90.5%
4946634 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.69 61.0 5.91e-01 100.0% 91.1%
5057694 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.68 60.0 5.65e-01 100.0% 95.0%
4023972 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.68 60.0 5.55e-01 100.0% 82.9%
3972645 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.67 58.0 4.91e-01 96.3% 67.4%
3405824 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.67 59.0 5.21e-01 100.0% 89.2%
4055533 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.66 57.0 5.30e-01 97.5% 88.6%
3720515 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.66 58.0 5.63e-01 100.0% 92.2%
3188465 1.1.7.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.65 57.0 4.96e-01 100.0% 97.7%
4181458 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.65 56.0 5.17e-01 100.0% 96.4%
3788725 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.65 56.0 5.14e-01 98.8% 92.7%
4069807 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.64 56.0 5.31e-01 100.0% 94.0%
3572941 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.64 56.0 5.14e-01 98.8% 94.3%
4995639 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.62 53.0 5.42e-01 96.3% 97.5%
4934153 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.62 55.0 5.25e-01 100.0% 86.3%
3742569 1.1.7.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.61 54.0 4.91e-01 100.0% 97.3%
3660831 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 51.0 4.79e-01 97.5% 80.0%
3923531 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.56 47.0 3.51e-01 100.0% 34.5%
3935286 11.2.1.58 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PF26186 0.56 45.0 3.52e-01 90.1% 67.9%
3700926 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.56 43.0 3.45e-01 84.0% 59.5%
3401979 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.56 49.0 3.64e-01 100.0% 41.4%
3216284 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.56 49.0 4.27e-01 100.0% 76.8%
4036608 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.55 43.0 2.90e-01 100.0% 21.2%
4157290 206.1.3.19 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › Dala_Dala_lig_C 0.55 43.0 3.09e-01 100.0% 27.6%
3297865 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.55 48.0 4.15e-01 96.3% 96.8%
3232211 11.2.1.58 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PF26186 0.55 44.0 3.39e-01 90.1% 71.0%
3268937 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 46.0 4.34e-01 98.8% 81.9%
3868227 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 45.0 4.38e-01 96.3% 88.4%
3368419 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.55 42.0 3.51e-01 84.0% 49.7%
3854448 10.1.1.10 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › MAM 0.54 45.0 3.41e-01 91.4% 75.5%
None — 0.54 41.0 3.19e-01 100.0% 34.9%
3979533 10.32.1.55 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Glft2_N 0.53 42.0 3.55e-01 86.4% 87.9%
4319133 206.1.3.19 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › Dala_Dala_lig_C 0.53 41.0 2.98e-01 100.0% 27.8%
3919708 11.2.1.17 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › NT-C2 0.53 41.0 3.23e-01 84.0% 45.6%
4150515 11.2.1.44 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_SHIP1-2_2nd 0.53 41.0 3.46e-01 85.2% 51.0%
3232218 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.53 42.0 3.32e-01 87.7% 43.3%
3759458 11.2.1.58 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PF26186 0.53 42.0 3.29e-01 88.9% 68.9%
3702000 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.53 41.0 3.32e-01 87.7% 41.8%
3474017 11.2.1.17 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › NT-C2 0.53 40.0 3.22e-01 84.0% 48.2%
3749227 10.32.1.216 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › MAM 0.52 42.0 3.25e-01 90.1% 77.4%
4953358 206.1.3.8 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 0.52 44.0 3.21e-01 100.0% 31.8%
3825489 11.1.1.1222 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF28628 0.51 42.0 3.77e-01 93.8% 83.3%
3999038 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.51 39.0 3.20e-01 84.0% 52.5%
3928662 11.10.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like 0.51 43.0 3.43e-01 100.0% 83.8%
3936582 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.51 43.0 3.27e-01 100.0% 42.7%
3949948 10.32.1.46 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Arabino_trans_C 0.50 42.0 3.21e-01 100.0% 44.0%
3252755 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.50 40.0 3.43e-01 86.4% 76.9%
D3 high residues 259-440
PDB
Domain cluster: rep: NC_074643__YP_010772404.1__QIT40-gp03__00003__D149-351
Pfam (4)
AccessionNameScoreE-valueQ covHMM cov
PF01443.25 best Viral_helicase1 29.0 1.30e-06 82.4% 44.3%
PF13604.13 AAA_30 35.6 1.10e-08 78.6% 59.7%
PF13245.13 AAA_19 39.3 9.70e-10 76.9% 89.5%
PF13086.13 AAA_11 32.8 9.00e-08 53.8% 32.3%
D4 high residues 460-591
PDB
Domain cluster: rep: IMGVR_UViG_3300009509_000914-3300009509-Ga0123573_1001185116__D490-580_655-727
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF13087.13 best AAA_12 41.0 2.20e-10 90.1% 55.9%
PF01443.25 Viral_helicase1 27.5 3.60e-06 81.8% 28.1%
PF13538.13 UvrD_C_2 30.5 3.80e-07 37.1% 92.3%