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nsp14

Euk-Vir

Tylonycteris_bat_coronavirus_HKU4

nsp14__YP_009944322__Tylonycteris_bat_coronavirus_HKU4__694007

Identity

Accession:
YP_009944322 ↗
Protein ID:
nsp14
Kingdom:
euk

Quality

86.8 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› Tylonycteris_bat_coronavirus_HKU4

TaxID: 694007

Cluster

View cluster (23 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 9-54
PDB
D2 medium residues 55-129_170-201_278-292
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF06471.20 best CoV_ExoN 114.9 5.60e-33 61.5% 14.4%
PF06471.20 CoV_ExoN 29.7 3.80e-07 29.5% 6.4%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wljA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 50.0 4.39e-01 75.4% 98.2%
5dk5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.66 51.0 4.31e-01 81.1% 99.0%
4okeA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.66 48.0 4.31e-01 74.6% 100.0%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.65 47.0 3.66e-01 75.4% 85.7%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 47.0 3.59e-01 78.7% 85.6%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 46.0 3.77e-01 76.2% 85.7%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 45.0 3.77e-01 74.6% 77.8%
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.61 46.0 3.79e-01 78.7% 94.0%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.60 43.0 3.65e-01 74.6% 78.0%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.57 51.0 3.98e-01 98.4% 85.9%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 52.0 3.93e-01 100.0% 85.7%
2p1jA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 37.0 3.59e-01 72.1% 87.7%
6d92A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 37.0 2.97e-01 71.3% 84.4%
1ekzA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 27.0 3.37e-01 73.0% 78.9%
1u04A04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.50 37.0 3.05e-01 76.2% 79.0%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4882792 2003.1.5.57 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CoV_ExoN 0.98 93.0 6.68e-01 96.7% 81.8%
3175633 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 53.0 4.36e-01 75.4% 99.0%
3510945 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.65 47.0 3.91e-01 74.6% 88.1%
4603831 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.64 48.0 3.75e-01 77.9% 68.2%
3250377 2484.1.1.13 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.63 46.0 3.67e-01 75.4% 70.4%
3798192 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.63 46.0 3.70e-01 76.2% 75.2%
3357118 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.62 44.0 3.70e-01 72.1% 80.0%
4333172 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.62 45.0 3.80e-01 75.4% 76.0%
3817801 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.62 45.0 3.51e-01 76.2% 70.0%
3368406 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.62 46.0 3.88e-01 77.0% 81.5%
4452101 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.61 46.0 3.79e-01 78.7% 92.7%
3435062 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.61 45.0 3.64e-01 75.4% 76.4%
3818775 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.61 45.0 3.65e-01 76.2% 76.4%
3360497 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.60 44.0 3.72e-01 75.4% 82.0%
11148 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 43.0 3.65e-01 74.6% 78.0%
5055106 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 44.0 3.79e-01 77.0% 90.2%
2117499 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.59 43.0 3.67e-01 76.2% 78.0%
4282509 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 48.0 3.12e-01 91.0% 58.4%
2801086 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.57 48.0 3.44e-01 91.0% 91.1%
4981192 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 48.0 3.75e-01 90.2% 92.5%
3997241 2484.1.1.13 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.56 40.0 3.91e-01 73.0% 95.5%
3185973 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.56 51.0 3.89e-01 99.2% 85.6%
5054032 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.56 48.0 3.35e-01 91.0% 94.1%
5017082 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.55 48.0 3.40e-01 91.8% 94.4%
5070158 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.53 45.0 3.28e-01 91.8% 83.5%
5035328 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.53 39.0 3.20e-01 77.0% 88.1%
5044376 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.51 43.0 3.20e-01 91.8% 87.4%
D3 medium residues 293-310_420-523
PDB
Domain cluster: rep: nsp14__YP_009513008_nsp14__Betacoronavirus_Erinaceus_VMC_DEU_2012__1385427__D437-524
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06471.20 best CoV_ExoN 141.5 5.00e-41 84.4% 18.8%
D4 medium residues 311-419
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06471.20 best CoV_ExoN 159.4 1.80e-46 100.0% 21.2%
CATH (62)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4pioA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.76 60.0 5.04e-01 83.5% 74.0%
8c9vA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 58.0 4.89e-01 82.6% 71.3%
2uyoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 64.0 4.75e-01 93.6% 57.8%
3a7eA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 57.0 4.55e-01 81.7% 63.2%
3ntvA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 64.0 5.12e-01 94.5% 67.6%
3ojoB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 56.0 4.58e-01 79.8% 58.2%
4xcxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 64.0 5.05e-01 94.5% 66.2%
2gpyB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 56.0 4.65e-01 81.7% 64.6%
3jwhA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 64.0 5.26e-01 95.4% 73.3%
3plnA03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 54.0 4.81e-01 80.7% 62.3%
6jp6D01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.70 57.0 4.50e-01 87.2% 76.8%
7uehA01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.70 51.0 5.01e-01 76.1% 95.7%
3douA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 55.0 4.72e-01 85.3% 89.1%
1ej0A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 56.0 4.71e-01 87.2% 90.0%
4m88A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 52.0 4.76e-01 80.7% 75.5%
4rkrD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 52.0 4.75e-01 81.7% 81.9%
7jt8I02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.67 47.0 4.33e-01 72.5% 86.8%
3duwA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.67 59.0 4.71e-01 98.2% 76.7%
3td9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 52.0 4.61e-01 81.7% 72.8%
1kqpA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.66 59.0 4.41e-01 97.2% 76.8%
2zfuA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 59.0 5.20e-01 98.2% 100.0%
3c3kA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 51.0 4.72e-01 81.7% 83.3%
1xngA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.65 57.0 4.39e-01 96.3% 78.1%
3gbvA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 51.0 4.58e-01 82.6% 78.5%
5fbhA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 50.0 4.15e-01 81.7% 60.4%
4e4yA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 53.0 4.13e-01 89.9% 71.5%
7vkkB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 56.0 4.39e-01 98.2% 76.6%
3lwsA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 56.0 4.26e-01 99.1% 53.8%
4ms4A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 53.0 4.38e-01 93.6% 61.3%
3lopA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 52.0 4.76e-01 92.7% 79.6%
4hutA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 47.0 3.99e-01 84.4% 71.2%
6jytA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 51.0 4.49e-01 94.5% 82.0%
1qz9A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.59 53.0 4.00e-01 98.2% 51.0%
4bloG01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 44.0 3.43e-01 79.8% 43.9%
3hutA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 50.0 4.49e-01 92.7% 75.3%
2eo5A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 50.0 3.81e-01 94.5% 59.1%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 4.00e-01 94.5% 50.5%
4b3fX01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.57e-01 94.5% 59.1%
3hl0A01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 52.0 4.62e-01 100.0% 89.9%
7b7tA03 3.40.50.2030 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 45.0 3.62e-01 85.3% 77.6%
2ykyA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 51.0 3.94e-01 98.2% 55.8%
2po3A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 51.0 4.05e-01 98.2% 58.3%
3d3kA00 3.40.50.10260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › YjeF N-terminal domain 0.56 47.0 3.75e-01 92.7% 72.1%
3tw8A02 3.40.50.11500 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › DENN domain, C-terminal lobe 0.56 42.0 3.70e-01 79.8% 56.7%
2orwB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 47.0 4.50e-01 94.5% 80.3%
4c7oA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 47.0 3.96e-01 94.5% 66.5%
2esbA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.55 46.0 4.10e-01 92.7% 98.1%
2xbuA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 50.0 4.09e-01 100.0% 84.0%
3ug7C00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 3.45e-01 94.5% 70.1%
2i1yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.55 41.0 3.15e-01 81.7% 72.8%
6yb3A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 45.0 3.58e-01 94.5% 61.2%
2b8tA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 45.0 4.18e-01 94.5% 81.3%
1d5rA01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.53 44.0 3.86e-01 93.6% 86.8%
4rflA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 47.0 4.41e-01 99.1% 91.0%
1r6xA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 45.0 3.71e-01 100.0% 87.3%
5aunB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 42.0 3.49e-01 94.5% 61.7%
2g6zA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 43.0 3.94e-01 93.6% 91.2%
1wchA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 43.0 3.17e-01 93.6% 71.1%
2oc3A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 43.0 3.25e-01 93.6% 80.3%
2hcmA01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 43.0 3.90e-01 93.6% 87.2%
2bzlA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 42.0 3.20e-01 93.6% 82.0%
3cr8C02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 39.0 3.34e-01 86.2% 86.9%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3059225 2003.1.5.57 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CoV_ExoN 0.97 76.0 7.75e-01 79.8% 86.8%
1567479 2003.1.5.57 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CoV_ExoN 0.96 93.0 6.99e-01 100.0% 50.4%
3925368 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.82 67.0 4.46e-01 86.2% 38.1%
5002998 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.78 72.0 5.65e-01 100.0% 68.8%
3838126 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.77 60.0 4.91e-01 82.6% 73.8%
3515728 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.77 60.0 3.67e-01 82.6% 19.7%
4973450 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.77 70.0 5.02e-01 98.2% 71.5%
5051955 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.76 69.0 5.54e-01 100.0% 82.9%
5071530 2003.1.5.14 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3 0.75 59.0 4.91e-01 82.6% 69.4%
3409414 2003.1.5.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bmt2 0.72 63.0 4.54e-01 94.5% 76.6%
3216123 2003.1.5.35 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › LCM 0.71 62.0 4.46e-01 94.5% 60.4%
4977716 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.71 62.0 5.65e-01 94.5% 80.7%
None — 0.71 58.0 4.36e-01 87.2% 62.3%
3584678 2003.1.5.97 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 0.71 65.0 5.21e-01 98.2% 87.2%
3893467 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.71 63.0 4.45e-01 94.5% 76.8%
3743216 2003.1.5.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bmt2 0.71 62.0 4.57e-01 93.6% 68.9%
4937406 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.71 51.0 4.73e-01 74.3% 88.9%
3876664 2003.1.5.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bmt2 0.71 62.0 4.48e-01 94.5% 76.3%
4184526 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.70 50.0 4.89e-01 74.3% 95.0%
5067350 7518.1.1.0 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like 0.70 50.0 5.08e-01 73.4% 95.2%
3644930 2003.1.5.139 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11+Sterol_MT_C 0.70 63.0 4.63e-01 100.0% 77.2%
4959227 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.69 50.0 4.71e-01 74.3% 93.1%
3838755 2003.1.5.32 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Cons_hypoth95 0.69 56.0 4.59e-01 86.2% 79.5%
3266012 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.68 59.0 4.59e-01 92.7% 88.0%
3587036 2007.1.2.10 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.68 52.0 4.92e-01 80.7% 85.4%
1253199 2007.1.2.13 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 0.68 52.0 4.88e-01 80.7% 81.2%
3192999 2003.1.5.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bmt2 0.68 59.0 4.40e-01 93.6% 74.7%
3358020 2003.1.5.45 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_8 0.68 61.0 4.75e-01 98.2% 72.6%
1406851 2007.1.2.10 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.67 52.0 4.88e-01 81.7% 88.8%
3385462 2007.1.2.13 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 0.67 52.0 4.57e-01 81.7% 69.8%
4483631 2005.1.1.18 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase 0.67 59.0 4.37e-01 96.3% 82.9%
None — 0.67 58.0 4.45e-01 96.3% 76.1%
5012331 7518.1.1.7 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › DacZ_T 0.66 47.0 4.95e-01 74.3% 96.0%
4935147 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.66 52.0 5.69e-01 96.3% 100.0%
None — 0.66 59.0 4.69e-01 98.2% 70.9%
3393851 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.66 51.0 4.64e-01 81.7% 66.2%
3624740 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.66 51.0 4.13e-01 81.7% 61.0%
3738071 129.1.1.51 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ADH_zinc_N 0.65 51.0 4.25e-01 84.4% 80.5%
149131 2003.1.1.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2 0.65 53.0 4.13e-01 89.9% 71.5%
4062514 2007.1.2.10 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 0.64 51.0 4.57e-01 84.4% 86.0%
3236889 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.64 52.0 5.33e-01 86.2% 97.1%
4929208 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.64 48.0 5.13e-01 78.9% 97.9%
5028374 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.63 51.0 5.32e-01 86.2% 94.0%
5030600 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.63 52.0 5.50e-01 98.2% 100.0%
3739730 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.63 47.0 4.03e-01 78.9% 49.7%
4928568 2006.1.2.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH 0.61 55.0 4.16e-01 99.1% 61.2%
4966910 7518.1.1.6 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › DacZ_A 0.60 43.0 4.19e-01 74.3% 85.8%
3198391 7512.1.1.20 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › EryCIII-like_C 0.59 44.0 3.48e-01 78.0% 60.9%
5061676 2007.1.2.58 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Hydant_A_N 0.57 42.0 3.69e-01 78.0% 68.8%
5063868 2004.1.1.101 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MeaB 0.57 48.0 3.69e-01 94.5% 44.4%
4140817 2006.1.1.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.57 49.0 3.89e-01 98.2% 95.0%
3590464 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.56 48.0 4.14e-01 93.6% 68.8%
4345417 2004.1.1.91 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › LpxK 0.55 48.0 3.74e-01 96.3% 49.6%
4117291 2004.1.1.43 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 0.55 46.0 3.79e-01 93.6% 60.0%
3246092 7515.1.1.12 ↗ a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › DUF229 0.54 45.0 3.27e-01 94.5% 54.8%
None — 0.53 38.0 2.83e-01 75.2% 36.0%
3385956 2005.1.1.15 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP-sulfurylase 0.52 46.0 3.58e-01 100.0% 62.0%
3929225 2007.2.3.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › DSPc 0.52 44.0 3.86e-01 93.6% 75.2%
3401420 2004.1.1.437 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ParA, AAA_31 0.52 43.0 3.38e-01 93.6% 56.5%
3262635 2007.2.3.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › DSPc 0.52 43.0 3.91e-01 93.6% 91.6%