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nsp1a

Euk-Vir

Bovine_astrovirus_B170_HK

nsp1a__YP_009010953__Bovine_astrovirus_B170_HK__1027244

Identity

Accession:
YP_009010953 ↗
Protein ID:
nsp1a
Kingdom:
euk

Quality

66.8 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Stellavirales› Astroviridae› Mamastrovirus› Bovine_astrovirus_B170/HK

TaxID: 1027244

Cluster

View cluster (19 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-95
PDB
D2 high residues 228-374
PDB
Domain cluster: rep: nonstructural_protein__YP_009154705__Astrovirus_Er_SZAL6_HUN_2011__1671382__D274-394_416-431
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5gl7A01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.64 48.0 4.58e-01 76.2% 99.4%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 43.0 3.96e-01 74.8% 94.7%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.58 41.0 4.08e-01 72.1% 87.6%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.58 42.0 4.10e-01 73.5% 88.5%
2olcA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.57 45.0 3.59e-01 81.0% 69.3%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 40.0 3.92e-01 74.1% 91.4%
7utzR02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 45.0 3.74e-01 89.8% 91.6%
1dbhA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.54 38.0 3.41e-01 72.8% 98.1%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 40.0 4.21e-01 80.3% 100.0%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 39.0 3.71e-01 77.6% 68.2%
2ntxA01 1.20.58.2010 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 0.52 38.0 3.37e-01 75.5% 71.0%
2b5dX02 1.20.1430.10 Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain 0.52 32.0 3.56e-01 74.1% 78.9%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5067364 5067.1.1.2 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.74 52.0 4.58e-01 70.1% 70.7%
3949475 5067.1.1.0 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.74 51.0 4.51e-01 70.1% 71.4%
4214107 3352.1.1.27 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › EpsG 0.71 63.0 4.77e-01 95.9% 100.0%
3239947 5067.1.1.2 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.69 49.0 4.26e-01 72.8% 68.9%
3938074 5067.1.1.0 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.67 51.0 4.40e-01 78.9% 80.9%
3728684 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 34.0 3.94e-01 72.1% 66.4%
3868214 109.4.1.1302 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30363 0.66 49.0 4.81e-01 76.2% 88.1%
3851222 304.28.1.34 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL, Sterol-sensing 0.62 51.0 3.09e-01 87.1% 31.8%
4948781 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.62 48.0 5.09e-01 80.3% 93.8%
3693707 5001.1.1.120 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TRP 0.60 51.0 3.81e-01 93.2% 99.2%
3200951 3281.1.2.3 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit 8 (Nqo8)-related › Proton_antipo_M 0.59 50.0 3.93e-01 89.8% 90.5%
3867729 141.1.1.27 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Tmp39 0.59 44.0 3.34e-01 76.9% 97.0%
4988202 1075.5.1.4 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.59 54.0 4.71e-01 99.3% 79.1%
3697260 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 45.0 4.02e-01 80.3% 100.0%
3172226 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.58 45.0 3.76e-01 81.0% 77.2%
3923182 174.1.1.43 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.57 44.0 4.40e-01 80.3% 97.3%
3267351 5001.1.1.32 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a 0.56 51.0 4.04e-01 100.0% 86.2%
3736269 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 39.0 3.40e-01 71.4% 63.0%
3589143 1075.5.1.4 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.55 49.0 4.30e-01 99.3% 83.1%
3286347 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.55 49.0 4.71e-01 95.2% 100.0%
3270377 5001.1.1.32 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a 0.54 49.0 3.96e-01 100.0% 84.2%
4943716 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.53 48.0 4.01e-01 100.0% 69.6%
3233878 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.52 39.0 4.19e-01 78.2% 97.6%
3389152 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.52 39.0 4.14e-01 77.6% 97.7%
4339023 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.51 46.0 4.07e-01 100.0% 80.5%
D3 high residues 420-568
PDB
Domain cluster: rep: 100_kDa_protein__YP_008130303__Citrus_vein_enation_virus__1301220__D379-571
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05579.20 best Peptidase_S32 28.9 9.20e-07 97.3% 37.7%
PF13365.13 Trypsin_2 45.0 2.70e-11 81.2% 100.0%
D4 high residues 724-795
PDB
Domain cluster: rep: nsp1ab__YP_009010952__Bovine_astrovirus_B170_HK__1027244__D724-780