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nsp1ab

Euk-Vir

Bovine_astrovirus_B170_HK

nsp1ab__YP_009010952__Bovine_astrovirus_B170_HK__1027244

Identity

Accession:: YP_009010952 ↗
Protein ID:: nsp1ab
Kingdom:: euk

Quality

70.7 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Stellavirales› Astroviridae› Mamastrovirus› Bovine_astrovirus_B170/HK

TaxID: 1027244

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 724-780

PDB

Domain cluster: representative

CATH (21)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1k04A02	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.76	56.0	4.55e-01	78.9%	76.9%
3u8vA00	1.20.120.660	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain	0.74	62.0	5.50e-01	94.7%	77.1%
1nzeA00	1.20.120.290	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle	0.72	60.0	4.88e-01	94.7%	71.4%
1st6A04	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.72	59.0	4.73e-01	93.0%	92.3%
6xz3A01	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.70	59.0	4.68e-01	94.7%	93.2%
1cpqA00	1.20.120.10	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562	0.70	57.0	4.52e-01	94.7%	73.6%
3t46A00	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.69	55.0	4.99e-01	86.0%	85.3%
2wb7A03	1.20.120.870	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain	0.69	55.0	4.22e-01	89.5%	66.2%
4kjmB01	1.20.5.420	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C	0.69	54.0	5.24e-01	86.0%	95.2%
1y4cA03	1.20.120.660	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain	0.67	55.0	4.49e-01	93.0%	65.5%
1aepA00	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.66	55.0	4.15e-01	100.0%	62.7%
3t6gB00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.63	51.0	4.06e-01	96.5%	82.8%
1kxpD04	1.10.246.10	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 ›	0.63	47.0	4.34e-01	82.5%	87.0%
3d1uA03	1.20.1270.240	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.62	46.0	3.96e-01	84.2%	63.4%
1sxjE03	1.20.272.10	Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 ›	0.62	51.0	4.43e-01	100.0%	81.4%
3bxjA02	1.10.506.20	Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 ›	0.60	48.0	4.26e-01	100.0%	71.4%
6ig5A01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.60	47.0	3.61e-01	87.7%	55.1%
4azcA02	1.20.1270.90	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like	0.58	45.0	4.48e-01	86.0%	94.9%
2gh9A02	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.58	43.0	3.07e-01	82.5%	75.0%
2e9fB01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.58	47.0	4.03e-01	91.2%	86.5%
8etcb01	1.20.120.1190	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.56	44.0	3.52e-01	100.0%	100.0%

ECOD (18)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4428893	601.18.1.2 ↗	alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › SMBP	0.73	61.0	5.28e-01	94.7%	76.7%
4209005	632.15.1.4 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70	0.72	58.0	5.25e-01	89.5%	81.2%
4036393	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.72	58.0	5.01e-01	89.5%	73.3%
5007277	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.71	58.0	5.09e-01	91.2%	85.9%
3286065	632.15.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN)	0.69	53.0	5.03e-01	87.7%	92.9%
5067410	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.66	51.0	4.49e-01	87.7%	83.3%
5060802	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.65	51.0	4.55e-01	87.7%	72.9%
5010292	601.30.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N	0.64	53.0	4.05e-01	100.0%	93.3%
4953007	632.11.1.1 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DUF357	0.63	49.0	4.55e-01	87.7%	89.3%
3603712	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.62	50.0	4.35e-01	96.5%	76.0%
3972698	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.62	49.0	4.37e-01	87.7%	75.3%
5074335	633.4.1.0 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor	0.62	47.0	3.99e-01	87.7%	56.0%
5044069	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.60	48.0	4.34e-01	89.5%	81.2%
3304016	601.16.1.8 ↗	alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218	0.60	50.0	3.69e-01	100.0%	91.2%
3337428	7579.1.1.5 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10	0.59	47.0	3.17e-01	96.5%	75.0%
4595958	632.22.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats	0.58	45.0	3.77e-01	91.2%	85.5%
3841428	6155.1.1.0 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter	0.57	41.0	3.62e-01	78.9%	74.4%
5028218	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.56	44.0	4.28e-01	91.2%	89.2%

D2 medium residues 7-94

PDB

D3 medium residues 233-362

PDB

D4 medium residues 411-489

PDB

Domain cluster: rep: ORF1a__YP_009162618__Dromedary_astrovirus__1662272__D428-481

D5 medium residues 490-568

PDB

Domain cluster: rep: ORF1a__YP_009047079__Human_astrovirus_BF34__1518575__D522-618

D6 medium residues 816-846_870-897_928-1030

PDB

Domain cluster: rep: NIa__YP_003620390__Freesia_mosaic_virus__421012__D109-224

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00680.26 best	RdRP_1	33.8	2.30e-08	77.2%	22.7%