nsp2

Euk-Vir

Rousettus_bat_coronavirus_HKU9

nsp2__YP_009924384__Rousettus_bat_coronavirus_HKU9__694006

Identity

73.1 mean pLDDT

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› Rousettus_bat_coronavirus_HKU9

TaxID: 694006

Singleton — not in a non-trivial cluster

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-83

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19211.6 best	CoV_NSP2_N	57.9	1.30e-15	82.9%	33.3%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5zb8A01	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.50	44.0	3.20e-01	100.0%	54.6%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4989144	108.4.1.0 ↗	alpha arrays › EF-hand › Hypothetical protein MTH865 › Hypothetical protein MTH865	0.56	39.0	4.35e-01	92.7%	100.0%
3622792	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.53	38.0	3.45e-01	78.0%	63.3%

D2 high residues 96-254

PDB

Domain cluster: rep: nsp2__YP_009915689__Murine_hepatitis_virus__11138__D110-226_244-292

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19211.6 best	CoV_NSP2_N	131.9	3.10e-38	78.6%	61.2%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2eqkA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.53	22.0	3.03e-01	77.4%	76.7%
2p4bB02	3.30.200.100	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain	0.51	25.0	3.09e-01	86.2%	72.4%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3166677	3792.1.1.0 ↗	beta sandwiches › 26S proteasome subunit Rpn2 C-terminal domain › 26S proteasome subunit Rpn2 C-terminal domain › 26S proteasome subunit Rpn2 C-terminal domain	0.65	28.0	3.69e-01	89.3%	71.8%
4991529	375.1.3.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184	0.59	22.0	3.46e-01	73.0%	86.7%
5041477	375.1.3.3 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817	0.58	23.0	3.38e-01	73.0%	88.3%

D3 high residues 298-413

PDB

D4 high residues 496-594

PDB

Domain cluster: rep: p87__NP_835357__Human_coronavirus_229E__11137__D681-785

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19212.6 best	CoV_NSP2_C	55.6	8.50e-15	99.0%	80.0%

D5 medium residues 414-481

PDB