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nsp2

Euk-Vir

Rabbit_coronavirus_HKU14

nsp2__YP_009924410__Rabbit_coronavirus_HKU14__1160968

Identity

Accession:: YP_009924410 ↗
Protein ID:: nsp2
Kingdom:: euk

Quality

68.4 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› Rabbit_coronavirus_HKU14

TaxID: 1160968

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-91

PDB

Domain cluster: rep: nsp2__YP_009924384__Rousettus_bat_coronavirus_HKU9__694006__D2-83

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF11963.14 best	B-CoV_A_NSP1	136.5	1.90e-39	100.0%	24.8%

D2 high residues 109-268

PDB

D3 high residues 299-371

PDB

D4 high residues 386-487

PDB

Domain cluster: representative

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ex4B02	2.30.30.10	Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral	0.59	21.0	2.78e-01	96.1%	54.2%
4x9cD00	2.30.30.100	Mainly Beta › Roll › SH3 type barrels. ›	0.59	22.0	2.83e-01	98.0%	56.7%
3bfmA02	2.30.30.100	Mainly Beta › Roll › SH3 type barrels. ›	0.58	21.0	3.09e-01	95.1%	72.1%
1lqlA01	2.20.25.10	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.58	19.0	3.11e-01	88.2%	100.0%
4akgA08	1.10.472.130	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain	0.56	42.0	3.68e-01	80.4%	84.6%
1h3dA01	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.55	41.0	3.81e-01	78.4%	96.2%
3kihC01	2.20.25.510	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.54	19.0	2.96e-01	87.3%	88.2%
4tr6A01	3.10.150.10	Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2	0.52	36.0	3.05e-01	95.1%	40.0%
3tx6A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	36.0	2.90e-01	72.5%	42.5%
1e88A03	2.10.70.10	Mainly Beta › Ribbon › Complement Module; domain 1 › Complement Module, domain 1	0.50	19.0	2.71e-01	89.2%	69.0%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4269668	7000.1.1.0 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS	0.59	33.0	4.17e-01	93.1%	100.0%
4972872	4.1.1.13 ↗	beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd	0.58	21.0	3.01e-01	95.1%	68.9%
4112791	4.8.1.5 ↗	beta barrels › SH3 › Chromo domain-like › Chromo domain-like › LytTR	0.55	26.0	3.40e-01	99.0%	86.0%
4440297	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.54	45.0	4.06e-01	90.2%	96.4%
4278911	4.8.1.5 ↗	beta barrels › SH3 › Chromo domain-like › Chromo domain-like › LytTR	0.54	25.0	3.36e-01	98.0%	86.0%
3736961	1075.1.1.20 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR	0.54	45.0	3.19e-01	93.1%	60.9%
5013701	3572.1.1.2 ↗	a+b complex topology › Cascade subunit Csa5 › Cascade subunit Csa5 › Cascade subunit Csa5 › Cas_Csa5	0.53	35.0	3.48e-01	98.0%	63.8%
4028730	2004.1.1.17 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head	0.53	46.0	2.82e-01	100.0%	38.0%
3988577	4.16.1.1 ↗	beta barrels › SH3 › PhtA domain-like › PhtA domain-like › Strep_his_triad	0.53	26.0	3.27e-01	100.0%	78.3%
4946181	304.28.1.0 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain	0.53	38.0	3.63e-01	85.3%	64.2%
5066058	7571.1.1.1 ↗	a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N	0.52	39.0	2.97e-01	79.4%	88.5%
4583847	3018.1.1.0 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like	0.51	35.0	3.89e-01	71.6%	95.0%
3823655	2003.1.5.31 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS	0.51	43.0	2.91e-01	96.1%	95.9%
3761667	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.51	30.0	3.31e-01	80.4%	73.8%
4938623	881.1.1.45 ↗	a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PF26686	0.51	45.0	3.86e-01	97.1%	96.8%

D5 high residues 510-592

PDB

Domain cluster: rep: nsp2__YP_009944311__Tylonycteris_bat_coronavirus_HKU4__694007__D585-649

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2526296	4.32.1.1 ↗	beta barrels › SH3 › Replicase polyprotein 1a N-terminal beta barrel domain › Replicase polyprotein 1a N-terminal beta barrel domain › NSP2_gammaCoV	0.72	62.0	5.57e-01	100.0%	67.8%
4968449	4312.1.1.15 ↗	a+b two layers › RelE-like › RelE-like › RelE-like › DUF4258	0.51	37.0	4.11e-01	80.7%	100.0%
4966645	4312.1.1.15 ↗	a+b two layers › RelE-like › RelE-like › RelE-like › DUF4258	0.50	37.0	3.98e-01	80.7%	94.2%
5061645	4312.1.1.15 ↗	a+b two layers › RelE-like › RelE-like › RelE-like › DUF4258	0.50	36.0	4.03e-01	78.3%	100.0%