nsp2

Euk-Vir

Human_coronavirus_HKU1

nsp2__YP_009944270__Human_coronavirus_HKU1__290028

Identity

74.4 mean pLDDT

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› Human_coronavirus_HKU1

TaxID: 290028

View cluster (13 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-91

PDB

Domain cluster: rep: nsp2__YP_009924384__Rousettus_bat_coronavirus_HKU9__694006__D2-83

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF11963.14 best	B-CoV_A_NSP1	155.9	2.50e-45	100.0%	24.8%

D2 high residues 105-280

PDB

Domain cluster: rep: nsp2__YP_009915689__Murine_hepatitis_virus__11138__D110-226_244-292

D3 high residues 345-475

PDB

Domain cluster: representative

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2mgxA00	1.20.940.10	Mainly Alpha › Up-down Bundle › RNA Binding Protein, Prp18; Chain A › Functional domain of the splicing factor Prp18	0.58	43.0	4.40e-01	84.0%	78.6%
2mqaA00	1.10.274.60	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain	0.57	38.0	3.91e-01	88.5%	71.2%
1t90A01	3.40.605.10	Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1	0.54	40.0	3.13e-01	76.3%	77.5%
1h6qA00	2.170.150.10	Mainly Beta › Beta Complex › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A	0.54	37.0	3.47e-01	80.9%	55.4%
4cybD00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.53	39.0	3.64e-01	77.1%	94.2%
1tjoB00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.53	39.0	3.61e-01	77.1%	82.3%
3s84A02	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.52	38.0	3.57e-01	74.8%	86.0%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3839085	5058.1.1.2 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st	0.52	32.0	3.64e-01	73.3%	80.0%
1300229	159.1.1.2 ↗	alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG-like	0.51	23.0	2.62e-01	85.5%	53.0%

D4 high residues 488-583

PDB

Domain cluster: rep: nsp2__YP_009944311__Tylonycteris_bat_coronavirus_HKU4__694007__D585-649

D5 medium residues 281-344

PDB