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nsp4
Euk-VirCanada_goose_coronavirus
nsp4__YP_009755913__Canada_goose_coronavirus__2569586
Identity
- Accession:
- YP_009755913 ↗
- Protein ID:
- nsp4
- Kingdom:
- euk
Quality
74.4
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Coronaviridae›
Gammacoronavirus›
Canada_goose_coronavirus
TaxID: 2569586
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 45-117
D2
high
residues 136-258
Domain cluster:
rep: nsp4__YP_009924360__Rat_coronavirus_Parker__502102__D130-270
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19217.6 best | CoV_NSP4_N | 125.7 | 4.00e-36 | 100.0% | 34.7% |
D3
high
residues 400-490
Domain cluster:
rep: nsp4_-TM2-__YP_009944272__Human_coronavirus_HKU1__290028__D409-483
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16348.11 best | CoV_NSP4_C | 104.0 | 8.70e-30 | 91.2% | 87.5% |
D4
medium
residues 312-391
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19217.6 best | CoV_NSP4_N | 34.2 | 2.70e-08 | 87.5% | 19.3% |
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.86 | 67.0 | 5.42e-01 | 81.2% | 60.3% |
| 1owlA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.69 | 49.0 | 4.25e-01 | 75.0% | 52.8% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 49.0 | 4.47e-01 | 77.5% | 89.9% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.67 | 57.0 | 5.30e-01 | 96.2% | 96.0% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.66 | 49.0 | 4.26e-01 | 81.2% | 87.2% |
| 3tjzB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.66 | 51.0 | 3.58e-01 | 93.8% | 25.4% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.65 | 44.0 | 3.75e-01 | 71.2% | 63.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.65 | 48.0 | 4.46e-01 | 81.2% | 87.7% |
| 1u3dA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 47.0 | 3.97e-01 | 77.5% | 52.2% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.64 | 47.0 | 4.22e-01 | 78.8% | 69.6% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.63 | 54.0 | 4.11e-01 | 96.2% | 89.3% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.63 | 42.0 | 3.23e-01 | 70.0% | 34.7% |
| 4cb8A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.62 | 53.0 | 3.30e-01 | 97.5% | 18.0% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 51.0 | 4.67e-01 | 100.0% | 95.4% |
| 4dtdA02 | 1.10.3680.20 | Mainly Alpha › Orthogonal Bundle › TerB-like › Actin cross-linking domain | 0.57 | 46.0 | 3.94e-01 | 90.0% | 75.2% |
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.57 | 42.0 | 4.09e-01 | 78.8% | 72.7% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 45.0 | 4.23e-01 | 90.0% | 99.0% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 39.0 | 3.96e-01 | 73.8% | 91.0% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 45.0 | 3.84e-01 | 91.3% | 75.8% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3786627 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 67.0 | 4.34e-01 | 100.0% | 25.5% |
| 3630285 | 109.4.1.1360 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF, NOC3p | 0.72 | 64.0 | 3.75e-01 | 100.0% | 18.7% |
| 3531310 | 109.4.1.574 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NOC3p | 0.71 | 63.0 | 4.54e-01 | 100.0% | 55.3% |
| 3926011 | 109.4.1.1360 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF, NOC3p | 0.71 | 64.0 | 3.81e-01 | 100.0% | 24.1% |
| 3718443 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.71 | 53.0 | 5.07e-01 | 80.0% | 94.7% |
| 3683126 | 109.3.1.319 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Adaptin_N | 0.71 | 59.0 | 5.02e-01 | 100.0% | 55.6% |
| 3290433 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.70 | 46.0 | 4.46e-01 | 98.8% | 60.0% |
| 3507345 | 109.4.1.828 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Htt_C-HEAT | 0.70 | 62.0 | 4.35e-01 | 98.8% | 72.9% |
| 3637359 | 604.10.1.7 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › DUF202 | 0.67 | 50.0 | 4.68e-01 | 80.0% | 92.0% |
| 3166640 | 109.4.1.1360 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF, NOC3p | 0.66 | 56.0 | 3.46e-01 | 95.0% | 24.1% |
| 3483099 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 55.0 | 5.13e-01 | 96.2% | 75.0% |
| 1206502 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.65 | 48.0 | 4.46e-01 | 81.2% | 87.7% |
| 3616195 | 603.1.1.148 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Keratin_assoc | 0.64 | 47.0 | 4.38e-01 | 78.8% | 91.3% |
| 3676995 | 109.4.1.1360 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF, NOC3p | 0.64 | 54.0 | 3.27e-01 | 97.5% | 24.5% |
| 3248733 | 109.4.1.335 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N | 0.64 | 54.0 | 3.22e-01 | 97.5% | 15.2% |
| 3267219 | 109.4.1.1556 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_HEAT, PDS5 | 0.63 | 55.0 | 4.15e-01 | 100.0% | 48.0% |
| 3611310 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 51.0 | 3.62e-01 | 96.2% | 27.6% |
| 3441715 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 55.0 | 4.97e-01 | 100.0% | 96.4% |
| 5019507 | 109.32.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Alkylsulfatase SdsA1 linker domain › Alkylsulfatase SdsA1 linker domain › Alkyl_sulf_dimr | 0.61 | 45.0 | 4.14e-01 | 87.5% | 59.1% |
| 3390092 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 51.0 | 4.31e-01 | 91.3% | 87.7% |
| 3682372 | 109.4.1.1361 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CAND1 | 0.60 | 50.0 | 4.01e-01 | 96.2% | 46.3% |
| 4993593 | 198.1.1.27 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF27234 | 0.60 | 45.0 | 4.56e-01 | 81.2% | 82.5% |
| 3201166 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.60 | 46.0 | 3.97e-01 | 85.0% | 88.1% |
| 3508186 | 7558.1.1.1 ↗ | a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase | 0.58 | 50.0 | 3.40e-01 | 97.5% | 51.0% |
| 3513743 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.54 | 45.0 | 3.67e-01 | 91.3% | 80.0% |
| 4562953 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.53 | 44.0 | 3.04e-01 | 92.5% | 52.6% |
| 3302084 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 46.0 | 4.38e-01 | 97.5% | 82.1% |