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nsp4
Euk-VirRousettus_bat_coronavirus_HKU9
nsp4__YP_009924386__Rousettus_bat_coronavirus_HKU9__694006
Identity
- Accession:
- YP_009924386 ↗
- Protein ID:
- nsp4
- Kingdom:
- euk
Quality
78.8
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Coronaviridae›
Betacoronavirus›
Rousettus_bat_coronavirus_HKU9
TaxID: 694006
Cluster
View cluster (24 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 42-118
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19217.6 best | CoV_NSP4_N | 93.4 | 2.70e-26 | 100.0% | 21.0% |
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7ejgC01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.34e-01 | 83.1% | 87.8% |
| 3mpkA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.41e-01 | 84.4% | 90.5% |
| 3vv5A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.38e-01 | 84.4% | 86.7% |
| 3delB02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.42e-01 | 84.4% | 88.2% |
| 4i62A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.39e-01 | 84.4% | 91.4% |
| 5wjpA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.59 | 45.0 | 4.26e-01 | 84.4% | 91.6% |
| 3upuA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 42.0 | 3.36e-01 | 77.9% | 86.9% |
| 4jdpA02 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.58 | 44.0 | 4.13e-01 | 83.1% | 99.0% |
| 1wdnA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.57 | 49.0 | 4.65e-01 | 100.0% | 93.8% |
| 3pdwA02 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.57 | 43.0 | 4.08e-01 | 83.1% | 99.0% |
| 5bwjD02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 43.0 | 4.10e-01 | 83.1% | 86.7% |
| 3mweB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.56 | 41.0 | 3.45e-01 | 79.2% | 100.0% |
| 4p56A00 | 3.40.190.170 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 | 0.55 | 42.0 | 2.83e-01 | 83.1% | 56.5% |
| 3rojA02 | 3.40.190.90 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › | 0.55 | 47.0 | 3.70e-01 | 97.4% | 86.8% |
| 1gtkA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 48.0 | 4.45e-01 | 100.0% | 95.0% |
| 3kbrA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 46.0 | 4.42e-01 | 100.0% | 97.8% |
| 3kosA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 40.0 | 3.80e-01 | 83.1% | 89.7% |
| 5lomA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 45.0 | 4.38e-01 | 100.0% | 93.4% |
| 1w36B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 45.0 | 3.23e-01 | 97.4% | 96.4% |
| 3pshA01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.53 | 42.0 | 3.32e-01 | 87.0% | 73.3% |
| 6jimB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 42.0 | 3.65e-01 | 93.5% | 69.2% |
| 3k4uA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 44.0 | 4.10e-01 | 100.0% | 92.9% |
| 4j1qA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 38.0 | 2.46e-01 | 83.1% | 40.8% |
| 4g2nA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.50 | 37.0 | 3.21e-01 | 80.5% | 74.4% |
| 1z7mE02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.50 | 43.0 | 4.19e-01 | 100.0% | 90.5% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3968309 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.63 | 47.0 | 4.15e-01 | 83.1% | 71.7% |
| 3968330 | 7523.1.1.4 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_3 | 0.62 | 47.0 | 3.40e-01 | 83.1% | 35.0% |
| 3586854 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.61 | 46.0 | 4.40e-01 | 84.4% | 88.4% |
| 5016403 | 7523.1.1.6 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Porphobil_deam | 0.60 | 46.0 | 4.29e-01 | 83.1% | 81.1% |
| 1518781 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.57 | 49.0 | 4.65e-01 | 100.0% | 93.8% |
| 4218062 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.56 | 42.0 | 3.95e-01 | 83.1% | 85.0% |
| 4024625 | 7523.1.1.6 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Porphobil_deam | 0.55 | 47.0 | 3.81e-01 | 100.0% | 85.6% |
| 4109257 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.54 | 47.0 | 4.28e-01 | 100.0% | 99.0% |
| 1521775 | 7523.1.1.16 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP | 0.54 | 40.0 | 3.94e-01 | 83.1% | 85.1% |
| 1523513 | 7523.1.1.16 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP | 0.53 | 40.0 | 3.79e-01 | 83.1% | 87.2% |
| 5017043 | 2003.1.1.75 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DUF1611_N | 0.52 | 38.0 | 3.64e-01 | 79.2% | 68.4% |
| 3784326 | 2007.2.3.30 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › PF29454 | 0.52 | 42.0 | 3.10e-01 | 92.2% | 89.6% |
| 2554477 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.52 | 46.0 | 4.07e-01 | 100.0% | 96.4% |
| 1874236 | 7523.1.1.16 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP | 0.52 | 39.0 | 3.74e-01 | 83.1% | 79.3% |
| 3489816 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.52 | 44.0 | 3.99e-01 | 100.0% | 74.5% |
| 1524226 | 7523.1.1.16 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP | 0.52 | 38.0 | 3.73e-01 | 83.1% | 83.1% |
| 3850361 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.51 | 44.0 | 3.93e-01 | 100.0% | 100.0% |
| 4948863 | 2007.1.14.5 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Peripla_BP_2 | 0.50 | 43.0 | 3.09e-01 | 97.4% | 31.7% |
D2
high
residues 276-394
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19217.6 best | CoV_NSP4_N | 84.4 | 1.50e-23 | 84.0% | 28.4% |
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.75 | 55.0 | 4.57e-01 | 77.3% | 77.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.72 | 55.0 | 5.59e-01 | 79.8% | 94.0% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.69 | 48.0 | 5.21e-01 | 72.3% | 100.0% |
| 1v9vA01 | 1.20.1480.20 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › MAST3 pre-PK domain-like | 0.66 | 48.0 | 5.30e-01 | 76.5% | 98.9% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.63 | 48.0 | 4.92e-01 | 79.8% | 93.9% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.62 | 41.0 | 4.10e-01 | 98.3% | 65.0% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 45.0 | 4.42e-01 | 75.6% | 73.2% |
| 1tzvA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.59 | 41.0 | 3.90e-01 | 79.0% | 60.3% |
| 1ymgA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.59 | 43.0 | 3.50e-01 | 76.5% | 95.7% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.59 | 41.0 | 3.56e-01 | 72.3% | 85.3% |
| 5tj5E00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.58 | 44.0 | 4.23e-01 | 79.8% | 93.5% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 46.0 | 3.99e-01 | 85.7% | 76.9% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 46.0 | 4.24e-01 | 85.7% | 81.9% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 43.0 | 4.64e-01 | 85.7% | 94.1% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.57 | 48.0 | 4.41e-01 | 91.6% | 98.1% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 45.0 | 4.40e-01 | 84.9% | 87.1% |
| 1r2jA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 45.0 | 4.27e-01 | 85.7% | 80.6% |
| 3c02A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.56 | 39.0 | 3.14e-01 | 71.4% | 95.9% |
| 6ljaA01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.56 | 48.0 | 3.40e-01 | 93.3% | 41.9% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 44.0 | 3.94e-01 | 85.7% | 83.6% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 40.0 | 4.28e-01 | 88.2% | 90.1% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 40.0 | 3.75e-01 | 75.6% | 80.6% |
| 1fx8A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.55 | 44.0 | 3.55e-01 | 89.9% | 92.1% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 44.0 | 4.06e-01 | 85.7% | 90.7% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 43.0 | 3.85e-01 | 85.7% | 77.1% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 44.0 | 4.31e-01 | 91.6% | 94.8% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 43.0 | 4.23e-01 | 87.4% | 87.2% |
| 3lysA00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.53 | 41.0 | 4.29e-01 | 90.8% | 96.2% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 42.0 | 3.53e-01 | 89.1% | 61.1% |
| 1v07A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 42.0 | 4.35e-01 | 89.1% | 100.0% |
| 1hxiA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 41.0 | 4.28e-01 | 95.0% | 92.9% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 42.0 | 4.07e-01 | 89.1% | 89.1% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 41.0 | 3.93e-01 | 88.2% | 91.7% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 42.0 | 4.07e-01 | 98.3% | 82.3% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3216931 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 59.0 | 4.96e-01 | 84.9% | 66.5% |
| 4328718 | 310.2.1.26 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › PigN | 0.72 | 55.0 | 5.41e-01 | 79.8% | 96.0% |
| 3346434 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 53.0 | 4.83e-01 | 82.4% | 74.4% |
| 3247041 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.67 | 52.0 | 4.96e-01 | 82.4% | 90.0% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.66 | 51.0 | 4.96e-01 | 82.4% | 86.9% |
| 4997481 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.66 | 48.0 | 5.16e-01 | 83.2% | 91.0% |
| 3593287 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 45.0 | 4.43e-01 | 73.1% | 71.5% |
| 4977760 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.63 | 52.0 | 5.25e-01 | 88.2% | 98.3% |
| 3661 | 633.10.1.1 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › 23S_rRNA_IVP | 0.63 | 48.0 | 4.93e-01 | 79.8% | 94.7% |
| 3972080 | 4953.1.1.29 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF1631 | 0.63 | 46.0 | 4.10e-01 | 77.3% | 84.6% |
| 3701078 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 48.0 | 4.67e-01 | 82.4% | 90.4% |
| 3258250 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.62 | 43.0 | 4.52e-01 | 72.3% | 80.0% |
| 169903 | 109.4.1.1691 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_17, TPR_19 | 0.60 | 39.0 | 4.29e-01 | 70.6% | 83.5% |
| 3293374 | 5048.1.1.1 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP | 0.59 | 44.0 | 3.58e-01 | 79.8% | 96.6% |
| 2394140 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.58 | 43.0 | 3.87e-01 | 77.3% | 82.8% |
| 3971610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.56 | 39.0 | 3.16e-01 | 71.4% | 72.7% |
| 3958873 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.56 | 45.0 | 4.21e-01 | 85.7% | 88.3% |
| 3332048 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.55 | 43.0 | 4.45e-01 | 98.3% | 88.2% |
| 3591522 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.55 | 46.0 | 3.82e-01 | 94.1% | 90.9% |
| 3286039 | 633.6.1.4 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_2 | 0.55 | 44.0 | 3.95e-01 | 87.4% | 82.1% |
| 5009480 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.54 | 42.0 | 3.86e-01 | 83.2% | 78.7% |
D3
high
residues 398-481
Domain cluster:
rep: nsp4_-TM2-__YP_009944272__Human_coronavirus_HKU1__290028__D409-483
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16348.11 best | CoV_NSP4_C | 91.5 | 7.00e-26 | 97.6% | 80.2% |
D4
medium
residues 128-268
Domain cluster:
rep: nsp4__YP_009924360__Rat_coronavirus_Parker__502102__D130-270
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19217.6 best | CoV_NSP4_N | 167.5 | 8.00e-49 | 100.0% | 39.8% |