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nsp4

Euk-Vir

SARS_coronavirus_Tor2

nsp4__YP_009944369__SARS_coronavirus_Tor2__227984

Identity

Accession:: YP_009944369 ↗
Protein ID:: nsp4
Kingdom:: euk

Quality

78.0 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Betacoronavirus› SARS_coronavirus_Tor2

TaxID: 227984

Cluster

View cluster (24 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 277-384

PDB

Domain cluster: rep: nsp4__YP_009924386__Rousettus_bat_coronavirus_HKU9__694006__D276-394

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19217.6 best	CoV_NSP4_N	70.0	3.60e-19	95.4%	28.7%

D2 high residues 402-487

PDB

Domain cluster: rep: nsp4_-TM2-__YP_009944272__Human_coronavirus_HKU1__290028__D409-483

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF16348.11 best	CoV_NSP4_C	122.1	2.00e-35	98.8%	87.5%

D3 medium residues 40-126

PDB

Domain cluster: rep: nsp4__YP_009924386__Rousettus_bat_coronavirus_HKU9__694006__D42-118

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19217.6 best	CoV_NSP4_N	79.8	3.80e-22	100.0%	23.6%

D4 medium residues 200-274

PDB

Domain cluster: rep: NSP4__YP_001941177__Turkey_coronavirus__11152__D222-291

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19217.6 best	CoV_NSP4_N	78.4	1.00e-21	100.0%	20.4%

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3fgyA00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.54	37.0	2.99e-01	84.0%	39.3%
1u04A04	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.52	40.0	2.93e-01	85.3%	67.9%
2fpnA02	3.30.360.40	Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › YwmB-like	0.52	37.0	3.94e-01	86.7%	84.6%
7d8gA01	2.40.380.10	Mainly Beta › Beta Barrel › FomD barrel-like fold › FomD-like	0.52	46.0	3.52e-01	97.3%	76.6%
2nlkA02	3.90.190.10	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily	0.51	42.0	3.01e-01	96.0%	50.0%
8ornD01	2.50.20.10	Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX	0.51	34.0	2.63e-01	90.7%	29.5%
3q45A01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.51	40.0	3.37e-01	85.3%	88.9%
4nehA01	2.130.10.130	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal	0.51	42.0	2.80e-01	100.0%	56.2%
2pgwA01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.50	41.0	3.25e-01	88.0%	85.3%
1xoiA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.50	35.0	2.12e-01	70.7%	81.3%
3bjsA01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.50	40.0	3.47e-01	86.7%	98.3%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4976925	821.1.1.4 ↗	a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › DUF123	0.54	42.0	3.39e-01	85.3%	85.0%
3568631	5.1.3.117 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1+Kelch_KLHDC2_KLHL20_DRC7	0.52	43.0	2.95e-01	98.7%	46.8%
4929601	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.51	42.0	2.86e-01	98.7%	37.1%
4025068	74.1.1.0 ↗	beta duplicates or obligate multimers › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain	0.51	29.0	3.42e-01	72.0%	83.7%