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ntpase,_DNA_primase
Euk-VirPteropox_virus
ntpase,_DNA_primase__YP_009268801__Pteropox_virus__1873698
Identity
- Accession:
- YP_009268801 ↗
- Protein ID:
- ntpase,_DNA_primase
- Kingdom:
- euk
Quality
87.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Pteropopoxvirus›
Pteropox_virus
TaxID: 1873698
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 494-693
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
D2
high
residues 695-783
Domain cluster:
rep: D5-like_helicase-primase__YP_009162463__Salmon_gill_poxvirus__1680908__D732-817
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03288.23 best | Pox_D5 | 47.4 | 3.10e-12 | 100.0% | 90.7% |
D3
medium
residues 1-67_134-151_176-220
Domain cluster:
rep: NTPase_-1-__YP_010377099__Monkeypox_virus__10244__D1-67_173-188_200-221
D4
medium
residues 68-133_152-175
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5u89A02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.60 | 48.0 | 4.01e-01 | 90.0% | 72.3% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.59 | 32.0 | 3.20e-01 | 93.3% | 47.8% |
| 1eteA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 42.0 | 3.72e-01 | 98.9% | 51.5% |
| 7r9xA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.55 | 44.0 | 3.69e-01 | 88.9% | 79.1% |
| 3fmbA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 49.0 | 4.76e-01 | 100.0% | 92.0% |
| 3fgrA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.54 | 40.0 | 3.55e-01 | 78.9% | 65.6% |
| 1gmuA01 | 3.30.70.790 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain | 0.52 | 33.0 | 3.67e-01 | 98.9% | 86.6% |
| 2qytA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 44.0 | 4.26e-01 | 96.7% | 84.2% |
| 2mraA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.51 | 36.0 | 3.26e-01 | 87.8% | 55.6% |
| 1ctfA00 | 3.30.1390.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L7/L12, C-terminal domain/Adaptor protein ClpS | 0.51 | 35.0 | 3.91e-01 | 93.3% | 95.6% |
| 1n4nA00 | 3.30.30.10 | Alpha Beta › 2-Layer Sandwich › Defensin A-like › Knottin, scorpion toxin-like | 0.51 | 26.0 | 3.24e-01 | 88.9% | 85.1% |
| 1oj7A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.51 | 41.0 | 3.19e-01 | 90.0% | 86.3% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3343002 | 309.1.1.4 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C | 0.63 | 56.0 | 3.32e-01 | 100.0% | 24.7% |
| 3590341 | 309.1.1.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase | 0.62 | 55.0 | 4.35e-01 | 100.0% | 85.6% |
| 4961139 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.60 | 51.0 | 4.62e-01 | 92.2% | 84.2% |
| 3718659 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.58 | 52.0 | 3.14e-01 | 100.0% | 15.6% |
| 3838738 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.57 | 48.0 | 4.29e-01 | 92.2% | 80.8% |
| 4949748 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.56 | 45.0 | 4.08e-01 | 87.8% | 72.8% |
| 4996727 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.56 | 47.0 | 4.34e-01 | 92.2% | 87.0% |
| 4021753 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.56 | 41.0 | 4.27e-01 | 90.0% | 82.4% |
| 4622885 | 218.2.1.1 ↗ | a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 | 0.55 | 35.0 | 3.50e-01 | 100.0% | 61.1% |
| 3589979 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.55 | 46.0 | 4.30e-01 | 91.1% | 90.0% |
| 3602384 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.55 | 47.0 | 4.26e-01 | 94.4% | 83.3% |
| 4940988 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.55 | 45.0 | 4.25e-01 | 92.2% | 92.7% |
| 5017844 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.54 | 46.0 | 4.21e-01 | 94.4% | 84.2% |
| 3237519 | 331.2.1.0 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain | 0.54 | 42.0 | 4.29e-01 | 86.7% | 95.6% |
| 3965604 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.53 | 43.0 | 4.00e-01 | 88.9% | 78.3% |
| 3607101 | 309.1.1.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase | 0.53 | 46.0 | 3.50e-01 | 100.0% | 78.5% |
| 3447167 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.52 | 43.0 | 4.35e-01 | 100.0% | 94.4% |
| 3838713 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.52 | 31.0 | 3.67e-01 | 81.1% | 90.0% |
| 4026521 | 301.1.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › Ribosomal_L7Ae | 0.52 | 41.0 | 3.28e-01 | 84.4% | 79.4% |
D5
medium
residues 244-321
Domain cluster:
rep: NTPase,_DNA_primase__YP_008003627__Mythimna_separata_entomopoxvirus_L__1293572__D258-347
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yk0A03 | 1.20.58.1930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 37.0 | 2.71e-01 | 70.5% | 31.3% |
| 3eb8B01 | 3.10.450.460 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain | 0.54 | 36.0 | 3.99e-01 | 82.1% | 90.2% |
| 1o70A02 | 2.30.180.10 | Mainly Beta › Roll › FAS1 domain › FAS1 domain | 0.53 | 43.0 | 3.50e-01 | 91.0% | 60.3% |
| 5lohB01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.53 | 38.0 | 3.90e-01 | 88.5% | 81.1% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5021955 | 375.1.1.9 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-C4_Topoisom | 0.60 | 35.0 | 4.08e-01 | 74.4% | 86.0% |
| 3594326 | 241.10.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › GAS2 domain › GAS2 domain | 0.59 | 49.0 | 4.88e-01 | 98.7% | 88.7% |
| 3195886 | 316.1.1.56 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PF26128 | 0.59 | 36.0 | 2.37e-01 | 97.4% | 12.8% |
| 4887360 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.59 | 31.0 | 3.42e-01 | 92.3% | 61.7% |
| 4312097 | 295.1.1.15 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › UPF0128 | 0.59 | 42.0 | 3.24e-01 | 74.4% | 33.1% |
| 3276222 | 316.1.1.56 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PF26128 | 0.58 | 42.0 | 3.06e-01 | 100.0% | 26.5% |
| 3550232 | 389.1.1.1 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › EGF | 0.57 | 31.0 | 3.08e-01 | 85.9% | 45.9% |
| 4046018 | 375.1.1.9 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-C4_Topoisom | 0.57 | 38.0 | 3.88e-01 | 100.0% | 70.7% |
| 1099437 | 3180.1.1.1 ↗ | a+b two layers › LEE-encoded effector EspG N-terminal domain-related › LEE-encoded effector EspG N-terminal domain-related › LEE-encoded effector EspG N-terminal domain-related › EspG | 0.54 | 37.0 | 3.86e-01 | 84.6% | 80.0% |
| 3703427 | 708.1.1.0 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain | 0.53 | 40.0 | 3.50e-01 | 82.1% | 59.2% |
| 3883146 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.53 | 31.0 | 3.50e-01 | 85.9% | 93.3% |
| 3840117 | 207.2.1.83 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › VacA2 | 0.52 | 41.0 | 2.39e-01 | 88.5% | 9.1% |
| 4156336 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.51 | 41.0 | 3.55e-01 | 97.4% | 54.6% |
| 3272453 | 6.1.1.7 ↗ | beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil › CDtoxinA | 0.51 | 40.0 | 3.42e-01 | 100.0% | 51.1% |
| 3981113 | 283.2.1.1 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 | 0.51 | 41.0 | 3.70e-01 | 89.7% | 77.1% |
| 5052790 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.50 | 44.0 | 3.62e-01 | 100.0% | 86.7% |
| 5017760 | 7523.1.1.3 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 | 0.50 | 42.0 | 3.49e-01 | 100.0% | 86.3% |
| 5048181 | 101.1.2.819 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF27231 | 0.50 | 43.0 | 3.45e-01 | 100.0% | 77.1% |
D6
medium
residues 325-435
Domain cluster:
rep: NTPase__YP_784303__Nile_crocodilepox_virus__1285600__D325-405
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08706.17 best | D5_N | 37.8 | 3.30e-09 | 94.6% | 69.4% |