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nucleoprotein
Euk-VirMarburg_marburgvirus
nucleoprotein__YP_001531153__Marburg_marburgvirus__11269
Identity
- Accession:
- YP_001531153 ↗
- Protein ID:
- nucleoprotein
- Kingdom:
- euk
Quality
61.7
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Monjiviricetes›
Mononegavirales›
Filoviridae›
Orthomarburgvirus›
Orthomarburgvirus_marburgense
TaxID: 11269
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 227-363
Domain cluster:
rep: N__YP_009508485__Southwest_carpet_python_virus__2016402__D213-328
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05505.18 best | Ebola_NP | 310.8 | 3.10e-92 | 100.0% | 18.2% |
| PF06407.16 | BDV_P40 | 26.6 | 3.90e-06 | 97.1% | 25.2% |
D2
high
residues 635-694
D3
medium
residues 18-128
Domain cluster:
rep: nucleoprotein__YP_003815432__Bundibugyo_ebolavirus__565995__D39-144
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05505.18 best | Ebola_NP | 190.4 | 7.70e-56 | 100.0% | 14.7% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4okoA00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.59 | 45.0 | 3.37e-01 | 82.0% | 75.5% |
| 1qf9A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 45.0 | 3.77e-01 | 82.9% | 99.0% |
| 6ln3A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 44.0 | 3.67e-01 | 82.0% | 99.5% |
| 4bucA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.57 | 49.0 | 4.10e-01 | 96.4% | 94.6% |
| 4pk9A00 | 3.40.1090.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain | 0.57 | 48.0 | 3.42e-01 | 93.7% | 87.5% |
| 2c42A02 | 3.40.50.920 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 45.0 | 4.07e-01 | 90.1% | 92.4% |
| 2ha8B01 | 3.40.1280.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain | 0.54 | 41.0 | 3.70e-01 | 81.1% | 96.1% |
| 1q14A01 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.54 | 45.0 | 3.80e-01 | 91.9% | 82.3% |
| 3mtjA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 40.0 | 3.44e-01 | 80.2% | 86.0% |
| 4xb1A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.52 | 40.0 | 3.48e-01 | 83.8% | 96.2% |
| 4v1ag00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.51 | 33.0 | 3.06e-01 | 100.0% | 50.0% |
| 1nriA00 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.51 | 40.0 | 3.23e-01 | 89.2% | 65.3% |
| 3tmgB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.50 | 38.0 | 3.44e-01 | 81.1% | 93.6% |
| 4n4uB00 | 3.40.190.170 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 | 0.50 | 43.0 | 3.14e-01 | 93.7% | 79.5% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2476746 | 566.1.1.4 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Ebola_NP | 0.89 | 81.0 | 5.39e-01 | 100.0% | 28.0% |
| 2522010 | 566.1.1.0 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related | 0.87 | 82.0 | 5.51e-01 | 100.0% | 30.7% |
| 3284711 | 7579.1.1.9 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Esterase | 0.58 | 44.0 | 3.22e-01 | 82.0% | 80.9% |
| 4429420 | 7579.1.1.9 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Esterase | 0.56 | 43.0 | 3.11e-01 | 82.9% | 67.2% |
| 3803289 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.56 | 48.0 | 3.46e-01 | 96.4% | 82.6% |
| 3813528 | 7579.1.1.42 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 | 0.55 | 47.0 | 3.43e-01 | 96.4% | 82.4% |
| 3288795 | 2003.1.3.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain | 0.55 | 42.0 | 3.12e-01 | 80.2% | 96.8% |
| 3269741 | 2488.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase | 0.54 | 41.0 | 3.38e-01 | 81.1% | 74.3% |
| 4275105 | 2488.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase | 0.53 | 40.0 | 3.59e-01 | 82.0% | 93.3% |
| 4948952 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.52 | 39.0 | 3.00e-01 | 80.2% | 40.7% |
| 2429380 | 2002.1.1.41 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › A_deaminase | 0.52 | 37.0 | 2.72e-01 | 75.7% | 94.0% |
| 4027601 | 2485.1.1.19 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › L51_S25_CI-B8 | 0.51 | 34.0 | 3.40e-01 | 100.0% | 64.3% |
| 5070046 | 2004.1.1.191 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 | 0.51 | 38.0 | 3.31e-01 | 81.1% | 98.4% |
| 4249160 | 2006.1.3.6 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 | 0.50 | 37.0 | 3.60e-01 | 79.3% | 84.6% |
D4
medium
residues 129-221
Domain cluster:
rep: nucleoprotein__NP_066243__Zaire_ebolavirus__186538__D147-205_218-239
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05505.18 best | Ebola_NP | 201.2 | 4.40e-59 | 100.0% | 12.3% |