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nucleoprotein
Euk-VirWenling_frogfish_filovirus
nucleoprotein__YP_010085036__Wenling_frogfish_filovirus__2116487
Identity
- Accession:
- YP_010085036 ↗
- Protein ID:
- nucleoprotein
- Kingdom:
- euk
Quality
58.2
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Monjiviricetes›
Mononegavirales›
Filoviridae›
Striavirus›
Wenling_frogfish_filovirus
TaxID: 2116487
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 226-377
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05505.18 best | Ebola_NP | 64.4 | 9.80e-18 | 99.3% | 16.5% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1n93X02 | 1.10.3050.10 | Mainly Alpha › Orthogonal Bundle › borna disease virus nucleoprotein, domain 2 › borna disease virus nucleoprotein, domain 2 | 0.73 | 50.0 | 5.46e-01 | 83.6% | 82.7% |
| 2gicD02 | 1.10.3610.10 | Mainly Alpha › Orthogonal Bundle › Rhabdovirus nucleoprotein-like › Nucleoprotein | 0.68 | 58.0 | 5.35e-01 | 91.4% | 81.5% |
| 2gttJ02 | 1.10.3610.10 | Mainly Alpha › Orthogonal Bundle › Rhabdovirus nucleoprotein-like › Nucleoprotein | 0.68 | 59.0 | 5.46e-01 | 93.4% | 81.1% |
| 4jgiA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.65 | 22.0 | 3.02e-01 | 73.0% | 56.2% |
| 1op1A00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.62 | 32.0 | 4.18e-01 | 95.4% | 90.2% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 32.0 | 3.80e-01 | 72.4% | 73.5% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.58 | 30.0 | 3.58e-01 | 72.4% | 72.8% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.57 | 32.0 | 3.61e-01 | 87.5% | 70.4% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 31.0 | 3.39e-01 | 86.8% | 63.3% |
| 2qksA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 32.0 | 3.79e-01 | 73.0% | 81.1% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.54 | 27.0 | 3.22e-01 | 75.7% | 68.6% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 28.0 | 3.51e-01 | 84.9% | 83.9% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.52 | 30.0 | 3.44e-01 | 86.8% | 74.6% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.50 | 31.0 | 3.19e-01 | 91.4% | 61.2% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.50 | 35.0 | 3.74e-01 | 99.3% | 82.3% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2476746 | 566.1.1.4 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Ebola_NP | 0.94 | 73.0 | 5.25e-01 | 81.6% | 32.2% |
| 2749214 | 566.1.1.1 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Paramyxo_ncap | 0.81 | 60.0 | 4.37e-01 | 82.9% | 30.4% |
| 2522010 | 566.1.1.0 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related | 0.80 | 57.0 | 4.22e-01 | 75.7% | 30.7% |
| 1763953 | 566.1.1.3 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap | 0.79 | 57.0 | 4.21e-01 | 82.2% | 30.4% |
| 2769765 | 566.1.1.1 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Paramyxo_ncap | 0.77 | 59.0 | 4.26e-01 | 82.2% | 30.6% |
| 3230496 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.57 | 33.0 | 4.19e-01 | 86.8% | 100.0% |
| 3598647 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.55 | 31.0 | 4.09e-01 | 84.9% | 98.8% |
| 3939799 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 33.0 | 3.49e-01 | 91.4% | 63.6% |
| 3547209 | 192.15.1.204 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 | 0.54 | 32.0 | 3.81e-01 | 88.2% | 87.0% |
| 4393454 | 632.15.1.6 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 | 0.54 | 32.0 | 3.81e-01 | 88.2% | 87.0% |
| 3463843 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.54 | 36.0 | 3.89e-01 | 91.4% | 79.1% |
| 3249523 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.54 | 33.0 | 3.63e-01 | 88.2% | 75.8% |
| 5027736 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 44.0 | 4.17e-01 | 88.8% | 94.4% |
| 3721200 | 611.9.1.5 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › SesA | 0.52 | 40.0 | 4.26e-01 | 100.0% | 93.1% |
| 3339004 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.52 | 41.0 | 4.36e-01 | 100.0% | 93.3% |
| 3744787 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.52 | 32.0 | 3.44e-01 | 88.2% | 70.0% |
| 3917447 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 33.0 | 3.42e-01 | 88.2% | 67.9% |
| 3748369 | 174.1.1.3 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › p53-inducible11 | 0.50 | 31.0 | 3.21e-01 | 87.5% | 62.1% |
D2
medium
residues 1-124
D3
medium
residues 125-221
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6lcuA02 | 1.10.10.470 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4 | 0.65 | 45.0 | 4.40e-01 | 71.1% | 71.4% |
| 1s8nA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 37.0 | 4.47e-01 | 100.0% | 98.3% |
| 2qbyB03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 47.0 | 4.84e-01 | 83.5% | 100.0% |
| 7kypB01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.60 | 43.0 | 3.13e-01 | 74.2% | 74.0% |
| 3gi8C00 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.57 | 50.0 | 3.33e-01 | 100.0% | 87.8% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.57 | 41.0 | 3.60e-01 | 76.3% | 88.0% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 30.0 | 2.89e-01 | 85.6% | 44.0% |
| 1xjuA00 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.55 | 42.0 | 3.66e-01 | 83.5% | 85.9% |
| 1f5xA00 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 40.0 | 3.22e-01 | 80.4% | 65.9% |
| 4d2dA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 41.0 | 2.78e-01 | 88.7% | 41.7% |
| 3ckdA02 | 1.20.58.360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines | 0.52 | 34.0 | 3.19e-01 | 85.6% | 53.2% |
| 2yqdA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 39.0 | 3.67e-01 | 80.4% | 87.5% |
| 3swhB02 | 1.20.58.1100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 37.0 | 3.32e-01 | 100.0% | 54.5% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 42.0 | 4.13e-01 | 100.0% | 82.2% |
| 2nrlA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 39.0 | 3.46e-01 | 83.5% | 80.0% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2476746 | 566.1.1.4 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Ebola_NP | 0.89 | 83.0 | 5.39e-01 | 100.0% | 40.1% |
| 2522010 | 566.1.1.0 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related | 0.88 | 83.0 | 5.43e-01 | 100.0% | 52.8% |
| 1763953 | 566.1.1.3 ↗ | alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap | 0.81 | 75.0 | 4.93e-01 | 100.0% | 26.6% |
| 3248090 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.78 | 53.0 | 5.80e-01 | 73.2% | 85.0% |
| 3927392 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.75 | 53.0 | 5.76e-01 | 73.2% | 87.5% |
| 3216068 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.67 | 47.0 | 5.09e-01 | 73.2% | 89.7% |
| 4589278 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.66 | 59.0 | 5.75e-01 | 99.0% | 98.1% |
| 4023146 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.66 | 51.0 | 5.39e-01 | 82.5% | 100.0% |
| 3666060 | 2008.1.1.29 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 | 0.65 | 49.0 | 3.47e-01 | 79.4% | 54.2% |
| 3739247 | 109.4.1.482 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › V-ATPase_H_C | 0.65 | 39.0 | 3.56e-01 | 100.0% | 44.6% |
| 3627131 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.64 | 52.0 | 4.93e-01 | 88.7% | 100.0% |
| 3299663 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 37.0 | 3.69e-01 | 100.0% | 54.3% |
| 3541293 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 48.0 | 4.97e-01 | 88.7% | 98.9% |
| 3495911 | 188.1.1.0 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain | 0.58 | 40.0 | 3.13e-01 | 71.1% | 92.1% |
| 2845166 | 2004.1.1.76 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 | 0.57 | 50.0 | 3.41e-01 | 99.0% | 39.7% |
| 3289135 | 148.1.3.315 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF5682 | 0.56 | 39.0 | 4.40e-01 | 74.2% | 100.0% |
| 3395944 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.54 | 41.0 | 3.22e-01 | 80.4% | 66.0% |
| 4025314 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.54 | 49.0 | 4.18e-01 | 100.0% | 92.9% |
| 3174410 | 109.4.1.1764 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28917 | 0.53 | 36.0 | 3.00e-01 | 100.0% | 39.4% |
| 3175487 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.52 | 44.0 | 3.27e-01 | 100.0% | 85.6% |
| 3737997 | 4146.1.1.14 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like › Sec5 | 0.51 | 34.0 | 3.21e-01 | 99.0% | 56.5% |
| 3625860 | 601.20.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipophorin-III › Apolipophorin-III | 0.50 | 35.0 | 2.94e-01 | 73.2% | 92.8% |
| 3666334 | 2004.1.1.44 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PRK | 0.50 | 43.0 | 3.04e-01 | 100.0% | 63.7% |