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orf22

Euk-Vir

Alcelaphine_gammaherpesvirus_2

orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184

Identity

Accession:
YP_009044405 ↗
Protein ID:
orf22
Kingdom:
euk

Quality

82.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Macavirus› Alcelaphine_gammaherpesvirus_2

TaxID: 138184

Cluster

View cluster (43 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 129-148_255-374
PDB
Domain cluster: rep: ORF22__YP_438146__Ovine_gammaherpesvirus_2__10398__D278-376
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 109.8 2.00e-31 89.3% 24.6%
D2 medium residues 149-254
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 97.2 1.30e-27 100.0% 21.8%
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.95 91.0 6.16e-01 100.0% 33.8%
1mdcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.82 46.0 4.26e-01 91.5% 45.0%
1h54B01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.69 59.0 4.38e-01 92.5% 90.7%
3n8bA00 3.10.450.700 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.69 39.0 4.63e-01 83.0% 80.0%
1nkgA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.68 61.0 4.62e-01 99.1% 86.5%
1omoA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.67 47.0 4.16e-01 71.7% 92.6%
1d6uA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.67 56.0 3.70e-01 89.6% 90.7%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.66 56.0 3.66e-01 90.6% 84.7%
1pu4A03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.65 54.0 3.64e-01 90.6% 88.9%
4bboA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.65 47.0 4.60e-01 90.6% 69.9%
2nvnA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.62 37.0 3.57e-01 89.6% 53.3%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.61 37.0 3.60e-01 89.6% 54.2%
7ufsA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.61 52.0 3.98e-01 96.2% 91.6%
3g8yA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 44.0 2.98e-01 75.5% 37.3%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.60 52.0 3.99e-01 92.5% 78.9%
3w5mA06 2.60.420.10 Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 0.60 39.0 4.02e-01 73.6% 70.0%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.59 50.0 4.35e-01 91.5% 77.8%
2wcoA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.59 43.0 4.19e-01 75.5% 88.7%
4akmB00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.58 50.0 4.37e-01 92.5% 66.2%
2hzrA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 42.0 3.64e-01 75.5% 92.5%
2avtA02 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.58 48.0 3.88e-01 89.6% 92.0%
2qziA00 3.40.1720.10 Alpha Beta › 3-Layer(aba) Sandwich › Streptococcus thermophilus LMG 18311 protein like › Streptococcus thermophilus LMG 18311 protein like 0.57 43.0 4.47e-01 79.2% 97.0%
2kd2A01 2.40.128.180 Mainly Beta › Beta Barrel › Lipocalin › 0.56 40.0 4.46e-01 83.0% 95.2%
4r7kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 46.0 3.89e-01 87.7% 70.8%
3rbyA02 2.40.128.310 Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain 0.55 41.0 4.27e-01 84.9% 85.3%
1h91A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 40.0 3.36e-01 75.5% 88.3%
3qktD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 38.0 2.69e-01 72.6% 36.2%
6r3wA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 44.0 3.82e-01 87.7% 68.3%
2vf9A00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.53 40.0 3.80e-01 89.6% 66.4%
4xrtA02 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 41.0 3.64e-01 89.6% 57.5%
3ijtB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 42.0 3.82e-01 87.7% 73.4%
1pzdA01 2.60.40.1480 Mainly Beta › Sandwich › Immunoglobulin-like › Coatomer, gamma subunit, appendage domain 0.51 46.0 4.05e-01 100.0% 92.3%
6phxA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.50 36.0 3.74e-01 91.5% 84.2%
3djwA00 3.30.160.300 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.50 37.0 3.89e-01 76.4% 94.7%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095478 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.94 90.0 5.56e-01 100.0% 21.6%
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.82 77.0 4.83e-01 100.0% 29.6%
3632840 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.67 56.0 3.85e-01 90.6% 88.8%
5015778 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.67 60.0 4.45e-01 98.1% 85.7%
4024769 9.11.1.0 ↗ beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like 0.66 38.0 4.79e-01 74.5% 93.8%
4964031 7089.1.1.7 ↗ a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › DUF7543 0.65 37.0 4.58e-01 83.0% 87.1%
3265841 216.1.1.20 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › UBC_like 0.65 42.0 4.31e-01 88.7% 69.0%
4018118 12.3.1.40 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › TREH_N 0.64 58.0 4.28e-01 99.1% 97.0%
3576881 3347.1.1.0 ↗ beta meanders › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 0.64 45.0 4.63e-01 83.0% 77.0%
4030495 331.3.1.4 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › IP_trans 0.63 57.0 4.24e-01 100.0% 60.7%
3953302 331.2.1.1 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.61 40.0 4.05e-01 85.8% 67.3%
4958640 71.1.1.0 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB 0.61 42.0 3.58e-01 90.6% 43.7%
3894207 3369.1.1.1 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › Lamp2-like_luminal 0.60 52.0 4.55e-01 92.5% 79.9%
3538089 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.59 54.0 4.18e-01 100.0% 93.2%
3274430 12.3.1.40 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › TREH_N 0.59 53.0 4.27e-01 99.1% 93.8%
4962769 12.3.1.77 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › PF25978 0.59 51.0 3.91e-01 97.2% 80.8%
3368132 4099.1.1.4 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-O 0.59 42.0 4.01e-01 73.6% 64.2%
3326913 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.59 50.0 3.80e-01 91.5% 89.6%
3250134 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.59 48.0 4.56e-01 84.0% 80.8%
4277468 298.1.1.22 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Gal80p_C-like 0.59 49.0 3.79e-01 86.8% 99.1%
4964630 331.3.1.11 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.58 48.0 4.28e-01 85.8% 69.9%
3328470 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.58 41.0 3.87e-01 73.6% 61.5%
5039993 12.3.1.40 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › TREH_N 0.58 52.0 4.18e-01 98.1% 88.3%
4248683 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.57 50.0 4.07e-01 92.5% 61.6%
184900 6044.1.1.1 ↗ a+b three layers › DUF1827-like › DUF1827-like › DUF1827-like › DUF1827 0.57 43.0 4.47e-01 79.2% 97.0%
3520453 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.57 45.0 4.23e-01 84.9% 73.1%
4569249 9.14.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 0.56 41.0 4.39e-01 84.0% 88.9%
3225806 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 43.0 4.12e-01 80.2% 75.8%
4292366 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.56 49.0 3.98e-01 92.5% 67.9%
4362579 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.55 48.0 4.02e-01 92.5% 66.3%
4136961 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.55 48.0 4.03e-01 92.5% 66.3%
4310253 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.55 48.0 4.10e-01 92.5% 66.1%
4294796 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.54 47.0 3.98e-01 92.5% 67.1%
4961667 5084.1.1.45 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like › PF26421 0.54 43.0 4.17e-01 93.4% 78.3%
3288437 331.3.1.11 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.53 44.0 3.92e-01 89.6% 64.7%
3456597 897.1.1.1 ↗ a+b two layers › Acidic mitochondrial matrix protein p32-like › Acidic mitochondrial matrix protein p32 › Acidic mitochondrial matrix protein p32 › MAM33 0.52 41.0 3.53e-01 84.0% 56.0%
3715886 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.52 40.0 2.76e-01 94.3% 23.8%
3254506 5084.1.1.0 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like 0.51 41.0 3.58e-01 88.7% 64.8%
D3 medium residues 375-545
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009388523__Common_bottlenose_dolphin_gammaherpesvirus_1_strain_Sarasota__2022783__D447-588
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 192.9 1.30e-56 96.5% 32.7%
D4 medium residues 546-688
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 183.9 1.70e-54 99.3% 98.6%