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orf26

Euk-Vir

Alcelaphine_gammaherpesvirus_2

orf26__YP_009044409__Alcelaphine_gammaherpesvirus_2__138184

Identity

Accession:
YP_009044409 ↗
Protein ID:
orf26
Kingdom:
euk

Quality

82.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Macavirus› Alcelaphine_gammaherpesvirus_2

TaxID: 138184

Cluster

View cluster (76 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-140_286-304
PDB
Domain cluster: rep: capsid_triplex_subunit_2__NP_077456__Cercopithecine_alphaherpesvirus_9__35246__D3-114_290-314
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 160.7 7.30e-47 89.5% 44.6%
D2 medium residues 143-197
PDB
Domain cluster: rep: capsid_triplex_subunit_2__YP_010085901__Wood_mouse_herpesvirus__432370__D142-189
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 34.6 1.90e-08 100.0% 16.6%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 56.0 5.53e-01 87.3% 74.6%
5hb0D01 1.20.120.1880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleoporin, helical C-terminal domain 0.73 53.0 3.40e-01 83.6% 17.1%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 55.0 5.31e-01 85.5% 77.4%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.68 55.0 5.17e-01 87.3% 72.7%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.68 49.0 4.70e-01 89.1% 67.2%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.67 50.0 5.17e-01 81.8% 94.1%
7bqiA01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.66 58.0 4.25e-01 100.0% 100.0%
3tmpA01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.66 45.0 3.31e-01 72.7% 27.3%
6k6iA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 58.0 3.87e-01 100.0% 48.4%
3vkgA15 1.10.8.1220 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.65 46.0 3.86e-01 74.5% 54.3%
2hekA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.65 49.0 3.12e-01 83.6% 17.8%
1i7dA02 1.10.460.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 0.64 46.0 3.27e-01 76.4% 86.1%
5cbgA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 51.0 4.11e-01 85.5% 74.5%
5mmjo00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.64 55.0 4.96e-01 96.4% 86.7%
2zmdA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.64 54.0 3.92e-01 98.2% 88.1%
1knzA01 6.10.280.20 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rotavirus non-structural protein NSP3, N-terminal domain 0.60 46.0 3.74e-01 81.8% 52.9%
3d5lA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 50.0 5.15e-01 96.4% 100.0%
5cvrA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 50.0 4.34e-01 94.5% 86.9%
2w43A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.58 45.0 4.52e-01 85.5% 96.5%
1gs0A01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.58 51.0 3.90e-01 100.0% 43.4%
1bjaA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 41.0 3.47e-01 90.9% 46.3%
2ymmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 47.0 4.27e-01 94.5% 82.2%
3jw4A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.18e-01 96.4% 37.7%
1crnA00 3.30.1350.10 Alpha Beta › 2-Layer Sandwich › Crambin › Thionin-like 0.53 37.0 4.01e-01 83.6% 91.3%
1bhpA00 3.30.1350.10 Alpha Beta › 2-Layer Sandwich › Crambin › Thionin-like 0.52 37.0 3.94e-01 81.8% 91.1%
2m4eA00 1.20.120.1930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF16691 family 0.51 42.0 3.62e-01 90.9% 73.3%
4cvnA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 37.0 2.66e-01 81.8% 43.0%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3973900 192.8.1.331 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF4824 0.82 61.0 5.19e-01 78.2% 58.8%
4443881 558.1.1.0 ↗ alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain 0.76 61.0 5.31e-01 100.0% 58.7%
4176201 621.1.1.3 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.74 65.0 5.43e-01 100.0% 89.5%
3773705 3990.1.1.0 ↗ few secondary structure elements › Zinc finger domain in TOPLESS related protein 2 (TPR2) › Zinc finger domain in TOPLESS related protein 2 (TPR2) › Zinc finger domain in TOPLESS related protein 2 (TPR2) 0.70 49.0 4.33e-01 83.6% 49.4%
4017163 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 4.27e-01 100.0% 44.7%
3245188 3846.1.1.0 ↗ alpha bundles › IcmR › IcmR › IcmR 0.68 49.0 5.36e-01 85.5% 93.3%
4928784 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.67 44.0 2.95e-01 94.5% 18.0%
3319968 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 55.0 5.19e-01 94.5% 90.0%
3382916 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.66 49.0 2.83e-01 80.0% 11.7%
3974602 601.3.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.65 56.0 4.23e-01 100.0% 62.1%
3935495 101.1.1.357 ↗ alpha arrays › HTH › HTH › Three-helical HTH › ELP3_N 0.65 56.0 5.20e-01 98.2% 90.0%
4000709 101.1.1.21 ↗ alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 0.64 56.0 5.17e-01 98.2% 94.3%
3403695 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.64 48.0 3.68e-01 80.0% 74.4%
5055205 4954.1.1.1 ↗ a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 0.63 45.0 3.45e-01 74.5% 35.0%
3311115 101.1.10.46 ↗ alpha arrays › HTH › HTH › Cyclin-like › ELP3_N 0.63 51.0 4.72e-01 90.9% 84.3%
3512341 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.62 53.0 4.94e-01 98.2% 95.7%
4028665 101.1.2.303 ↗ alpha arrays › HTH › HTH › winged helix domain › RPC5 0.60 47.0 3.27e-01 83.6% 64.7%
3509156 101.1.2.352 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_Tnp_Tc5 0.60 49.0 4.64e-01 96.4% 100.0%
3702325 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.59 49.0 4.94e-01 94.5% 100.0%
4948984 225.2.1.1 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › Uncharacterized protein DIP2311 middle domain › Uncharacterized protein DIP2311 middle domain › HATPase_c_4 0.58 46.0 3.11e-01 94.5% 63.3%
4659871 3001.1.1.1 ↗ alpha arrays › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › Tetrahydrodipicolinate-N-succinlytransferase, N-terminal 3-helical domain › THDPS_N_2 0.57 49.0 4.14e-01 100.0% 73.7%
5067137 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 38.0 3.72e-01 80.0% 65.0%
1731538 101.1.1.25 ↗ alpha arrays › HTH › HTH › Three-helical HTH › DUF433 0.56 39.0 3.07e-01 78.2% 48.9%
4931105 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 39.0 3.16e-01 81.8% 75.2%
3919148 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.52 45.0 2.86e-01 100.0% 20.3%
3810856 4312.1.1.0 ↗ a+b two layers › RelE-like › RelE-like › RelE-like 0.51 44.0 3.34e-01 98.2% 48.1%
D3 medium residues 213-280
PDB
Domain cluster: rep: capsid_protein__YP_004207862__Cricetid_gammaherpesvirus_2__1605972__D219-292
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01802.24 best Herpes_V23 47.4 2.40e-12 100.0% 24.0%