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orf50
Euk-VirAlcelaphine_gammaherpesvirus_2
orf50__YP_009044431__Alcelaphine_gammaherpesvirus_2__138184
Identity
- Accession:
- YP_009044431 ↗
- Protein ID:
- orf50
- Kingdom:
- euk
Quality
50.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Alcelaphine_gammaherpesvirus_2
TaxID: 138184
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-94_185-212
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.70 | 62.0 | 5.73e-01 | 95.9% | 97.4% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.66 | 50.0 | 4.60e-01 | 100.0% | 61.1% |
| 3v0aB02 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.63 | 49.0 | 3.58e-01 | 81.1% | 67.4% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 57.0 | 5.04e-01 | 100.0% | 96.1% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 49.0 | 4.92e-01 | 99.2% | 82.3% |
| 1dk8A02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.62 | 36.0 | 4.26e-01 | 73.8% | 83.5% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.60 | 44.0 | 4.80e-01 | 80.3% | 92.1% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 46.0 | 4.97e-01 | 100.0% | 95.1% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 44.0 | 4.11e-01 | 93.4% | 61.8% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 38.0 | 4.34e-01 | 100.0% | 90.6% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 4.78e-01 | 99.2% | 98.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 49.0 | 4.85e-01 | 95.9% | 85.4% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.58 | 39.0 | 4.42e-01 | 98.4% | 95.5% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 48.0 | 4.44e-01 | 91.0% | 95.5% |
| 1tfkB00 | 1.20.120.650 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D | 0.56 | 38.0 | 4.44e-01 | 76.2% | 98.8% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 38.0 | 4.29e-01 | 95.9% | 93.4% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 42.0 | 4.66e-01 | 99.2% | 98.0% |
| 3bruB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 50.0 | 4.35e-01 | 100.0% | 98.4% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 44.0 | 4.62e-01 | 100.0% | 93.6% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.55 | 48.0 | 4.75e-01 | 96.7% | 90.7% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 44.0 | 4.25e-01 | 100.0% | 75.7% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.54 | 42.0 | 4.16e-01 | 83.6% | 78.3% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 42.0 | 3.46e-01 | 82.8% | 67.1% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 42.0 | 4.23e-01 | 99.2% | 81.2% |
| 1ylmA00 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.53 | 46.0 | 4.38e-01 | 100.0% | 80.3% |
| 5uh5D02 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.53 | 39.0 | 3.76e-01 | 75.4% | 84.8% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.53 | 43.0 | 4.40e-01 | 99.2% | 90.5% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.53 | 38.0 | 3.96e-01 | 77.0% | 89.6% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 40.0 | 4.10e-01 | 100.0% | 88.6% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 42.0 | 4.04e-01 | 95.9% | 95.2% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3660190 | 109.4.1.935 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TOR1L1_N | 0.69 | 47.0 | 4.13e-01 | 79.5% | 48.0% |
| 3591412 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.68 | 59.0 | 5.16e-01 | 93.4% | 86.7% |
| 3668973 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 45.0 | 4.69e-01 | 99.2% | 74.5% |
| 3924660 | 604.1.1.140 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27005 | 0.67 | 46.0 | 5.34e-01 | 97.5% | 100.0% |
| 3609189 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.66 | 57.0 | 5.01e-01 | 95.9% | 86.4% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.65 | 47.0 | 4.82e-01 | 100.0% | 78.3% |
| 5073131 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.64 | 48.0 | 4.85e-01 | 100.0% | 79.2% |
| 4086561 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.63 | 45.0 | 4.63e-01 | 99.2% | 77.4% |
| 3420616 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.63 | 48.0 | 3.93e-01 | 80.3% | 63.2% |
| 3270160 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.63 | 47.0 | 5.09e-01 | 96.7% | 95.0% |
| 3471904 | 601.1.1.57 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 | 0.61 | 44.0 | 4.59e-01 | 98.4% | 80.0% |
| 3702019 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 48.0 | 4.21e-01 | 86.1% | 86.1% |
| 3593068 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 43.0 | 3.64e-01 | 74.6% | 91.0% |
| 3495368 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 3.31e-01 | 85.2% | 70.3% |
| 3514842 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.59 | 46.0 | 4.98e-01 | 96.7% | 97.1% |
| 4484523 | 5067.1.1.10 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › PIG-F | 0.58 | 41.0 | 3.63e-01 | 73.0% | 100.0% |
| None | — | 0.57 | 42.0 | 3.99e-01 | 75.4% | 85.0% | |
| 4581643 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.57 | 51.0 | 4.67e-01 | 100.0% | 75.0% |
| 5047547 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.57 | 47.0 | 4.80e-01 | 90.2% | 95.7% |
| 3788410 | 109.4.1.88 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MUN | 0.56 | 50.0 | 3.25e-01 | 99.2% | 37.6% |
| 4934608 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 46.0 | 4.45e-01 | 100.0% | 78.6% |
| 3804219 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 35.0 | 4.06e-01 | 78.7% | 87.8% |
| 3664670 | 604.1.1.189 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Occludin_ELL | 0.54 | 38.0 | 3.66e-01 | 73.0% | 97.2% |
| 5070237 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.54 | 39.0 | 4.33e-01 | 88.5% | 100.0% |
| 4526844 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 49.0 | 4.32e-01 | 100.0% | 70.9% |
| 3609309 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 47.0 | 3.84e-01 | 100.0% | 65.8% |
| 4072617 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.51 | 46.0 | 4.24e-01 | 100.0% | 77.5% |
| 3678146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.51 | 39.0 | 3.82e-01 | 82.0% | 79.3% |
| 3754509 | 3782.1.1.0 ↗ | a+b duplicates or obligate multimers › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related | 0.51 | 39.0 | 3.76e-01 | 81.1% | 90.0% |
| 3722652 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.50 | 39.0 | 3.70e-01 | 82.8% | 69.6% |
D2
medium
residues 95-184
Domain cluster:
rep: ORF50__YP_010084594__Macaca_nemestrina_rhadinovirus_2__123630__D113-208
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03326.19 best | Herpes_TAF50 | 123.5 | 1.70e-35 | 100.0% | 16.6% |