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origin_binding_protein
Euk-VirHuman_betaherpesvirus_6B
origin_binding_protein__NP_050252__Human_betaherpesvirus_6B__32604
Identity
- Accession:
- NP_050252 ↗
- Protein ID:
- origin_binding_protein
- Kingdom:
- euk
Quality
70.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_6B
TaxID: 32604
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 24-199
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 289.9 | 5.80e-86 | 100.0% | 22.8% |
D2
high
residues 204-350_413-454
Domain cluster:
rep: CP025712.1__AUO37541.1__YDC107_5424__00064__D413-546_602-643
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 209.2 | 1.40e-61 | 78.3% | 15.7% |
| PF02399.22 | Herpes_ori_bp | 43.0 | 2.50e-11 | 23.3% | 5.1% |
D3
medium
residues 351-412
D4
medium
residues 462-533
D5
medium
residues 534-613
D6
medium
residues 614-697
Domain cluster:
rep: DNA_replication_origin-binding_helicase__YP_009344918__Murine_roseolovirus__1940555__D581-690
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 72.1 | 4.00e-20 | 100.0% | 10.6% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rrkA02 | 1.20.1460.20 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › | 0.65 | 40.0 | 3.28e-01 | 82.1% | 32.9% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 42.0 | 3.62e-01 | 72.6% | 84.4% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.59 | 43.0 | 4.69e-01 | 78.6% | 97.0% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.57 | 41.0 | 4.12e-01 | 77.4% | 85.1% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.56 | 44.0 | 3.70e-01 | 84.5% | 87.7% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 41.0 | 4.19e-01 | 78.6% | 78.6% |
| 3crmA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.56 | 45.0 | 4.54e-01 | 97.6% | 89.3% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.54 | 43.0 | 4.27e-01 | 84.5% | 93.1% |
| 2qkwA00 | 1.20.1270.140 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto | 0.54 | 41.0 | 3.91e-01 | 83.3% | 92.1% |
| 2qgnA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.54 | 43.0 | 4.37e-01 | 97.6% | 90.2% |
| 1kblA05 | 1.20.80.30 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.53 | 41.0 | 4.05e-01 | 82.1% | 91.0% |
| 4m7cB00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.52 | 42.0 | 3.36e-01 | 94.0% | 84.3% |
| 2jnsA01 | 1.20.1270.220 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 40.0 | 4.13e-01 | 91.7% | 90.1% |
| 3fhnA05 | 1.10.10.2270 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Dsl1p vesicle tethering complex, Tip20p subunit, domain E | 0.50 | 30.0 | 3.25e-01 | 95.2% | 71.6% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4521202 | 160.1.1.3 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › T3SS_ATPase_C | 0.65 | 47.0 | 4.94e-01 | 76.2% | 100.0% |
| 3470044 | 109.54.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp21 | 0.61 | 46.0 | 3.37e-01 | 81.0% | 51.9% |
| 3420431 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 42.0 | 4.26e-01 | 77.4% | 77.6% |
| 4462833 | 160.1.1.4 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_VA_C | 0.58 | 46.0 | 4.37e-01 | 86.9% | 95.0% |
| 3490268 | 148.1.3.13 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 | 0.58 | 45.0 | 2.98e-01 | 83.3% | 46.4% |
| 4322565 | 632.15.1.4 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70 | 0.57 | 42.0 | 4.20e-01 | 77.4% | 78.8% |
| 3824929 | 1189.1.1.18 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › SEO_N | 0.56 | 41.0 | 3.01e-01 | 78.6% | 39.2% |
| 3803972 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.56 | 35.0 | 3.79e-01 | 91.7% | 75.7% |
| 3260614 | 632.6.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit | 0.55 | 43.0 | 4.26e-01 | 85.7% | 94.4% |
| 3731997 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.55 | 44.0 | 3.86e-01 | 86.9% | 95.2% |
| 3973396 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.55 | 38.0 | 3.70e-01 | 73.8% | 64.2% |
| 3286912 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.54 | 40.0 | 3.91e-01 | 79.8% | 77.9% |
| 4042010 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.54 | 39.0 | 4.12e-01 | 77.4% | 88.0% |
| 3551603 | 109.4.1.119 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRF | 0.54 | 40.0 | 3.11e-01 | 82.1% | 76.7% |
| 4176972 | 160.1.1.1 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C | 0.52 | 42.0 | 3.64e-01 | 90.5% | 87.1% |
| 4666969 | 160.1.1.0 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0.52 | 42.0 | 3.62e-01 | 90.5% | 87.9% |
| 4469533 | 1.1.9.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg | 0.52 | 43.0 | 3.13e-01 | 95.2% | 33.8% |
| 4961644 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.52 | 43.0 | 3.03e-01 | 96.4% | 76.1% |
| 3603690 | 601.37.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › Photosystem II lipoprotein Psb27 › Photosystem II lipoprotein Psb27 › PF27232 | 0.52 | 42.0 | 3.49e-01 | 94.0% | 69.1% |
| 4461833 | 160.1.1.1 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C | 0.51 | 42.0 | 3.67e-01 | 90.5% | 93.1% |
| 3569684 | 108.1.1.95 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › CCD48 | 0.51 | 38.0 | 3.64e-01 | 78.6% | 68.4% |
| 3900656 | 3831.1.1.6 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › POF1B_HlH | 0.51 | 39.0 | 3.93e-01 | 81.0% | 90.6% |
| 4011748 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.51 | 40.0 | 3.96e-01 | 90.5% | 98.9% |
D7
medium
residues 698-762
Domain cluster:
rep: DNA_replication_origin-binding_helicase_UL9__YP_009230139__Leporid_alphaherpesvirus_4__481315__D730-784
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 72.4 | 3.30e-20 | 100.0% | 7.7% |