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p-loop_NTPase

Euk-Vir

Homarus_gammarus_nudivirus

p-loop_NTPase__YP_010087693__Homarus_gammarus_nudivirus__2509616

Identity

Accession:
YP_010087693 ↗
Protein ID:
p-loop_NTPase
Kingdom:
euk

Quality

61.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 163-251_326-407
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1khtB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.78 56.0 5.37e-01 72.5% 100.0%
3lv8A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 55.0 5.14e-01 77.8% 100.0%
5uivA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 55.0 4.97e-01 78.4% 96.0%
1e9fA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 53.0 5.02e-01 78.4% 96.5%
2bdtA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 48.0 4.80e-01 74.9% 98.8%
2qorA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 47.0 5.39e-01 76.0% 100.0%
6wctD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 46.0 4.95e-01 78.4% 89.8%
1z8fA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 43.0 5.00e-01 75.4% 100.0%
1tzbA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.59 41.0 4.44e-01 84.8% 85.6%
1fvpA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.55 41.0 3.75e-01 78.4% 99.6%
3fj1A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 40.0 3.92e-01 84.8% 77.7%
3fxaA00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.50 41.0 3.96e-01 86.5% 81.2%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4943200 2004.1.1.79 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.77 58.0 5.39e-01 77.2% 96.7%
4933472 2004.1.1.79 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.77 59.0 5.32e-01 78.4% 99.1%
5025416 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.77 57.0 5.36e-01 75.4% 99.5%
4946728 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.77 57.0 5.30e-01 76.6% 96.7%
4569464 2004.1.1.79 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.76 55.0 5.27e-01 73.7% 100.0%
4945369 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.75 57.0 5.22e-01 77.8% 98.1%
4185559 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 55.0 5.04e-01 77.2% 95.9%
4029897 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.72 54.0 5.28e-01 76.6% 99.5%
4433845 2004.1.1.71 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPPT 0.72 53.0 4.47e-01 75.4% 90.7%
None 0.70 51.0 4.89e-01 75.4% 93.5%
5043508 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.69 49.0 4.93e-01 72.5% 88.0%
3890291 2004.1.1.41 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK 0.67 51.0 4.22e-01 78.4% 94.1%
4361709 2004.1.1.105 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinase-PPPase 0.64 46.0 4.80e-01 73.1% 79.4%
4645891 2004.1.1.105 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinase-PPPase 0.64 47.0 4.91e-01 75.4% 80.6%
3875685 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 48.0 4.06e-01 77.2% 94.9%
4002879 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.58 44.0 4.30e-01 78.4% 97.4%
3233964 2004.1.1.104 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sulfotransfer_2 0.56 41.0 3.69e-01 75.4% 73.3%
4278210 2007.6.1.0 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain 0.55 44.0 4.41e-01 84.8% 84.0%
3938140 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 41.0 3.69e-01 77.8% 86.0%
4999206 2007.6.1.5 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.53 41.0 3.95e-01 84.8% 70.8%
3595117 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.50 26.0 2.44e-01 89.5% 38.6%
1114698 2007.6.1.4 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.50 41.0 3.96e-01 86.5% 80.7%
D2 medium residues 252-325
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 51.0 4.08e-01 86.5% 47.0%
5djsA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 40.0 3.24e-01 100.0% 36.4%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.58 36.0 2.85e-01 100.0% 27.7%
2qgaB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.58 40.0 3.54e-01 73.0% 60.5%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.57 38.0 3.90e-01 90.5% 74.6%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.54 45.0 4.28e-01 100.0% 78.1%
3u1nB01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.54 41.0 2.81e-01 87.8% 67.7%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.54 45.0 3.75e-01 100.0% 85.6%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 40.0 4.34e-01 100.0% 95.2%
1imvA02 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.53 42.0 3.12e-01 87.8% 99.0%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 37.0 4.02e-01 93.2% 98.2%
1wz9A01 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.51 40.0 2.92e-01 87.8% 98.6%
3smvA02 1.10.150.750 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.51 30.0 3.02e-01 73.0% 53.2%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.51 36.0 3.58e-01 81.1% 71.2%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.51 36.0 3.56e-01 95.9% 69.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 42.0 3.40e-01 95.9% 74.3%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3630104 192.24.1.6 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.70 52.0 3.27e-01 78.4% 18.4%
3582573 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.66 51.0 4.51e-01 83.8% 61.8%
3223457 101.1.2.661 alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD 0.63 46.0 3.13e-01 78.4% 25.0%
3461645 109.4.1.628 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HUS 0.62 46.0 2.81e-01 82.4% 12.3%
3967364 4990.1.1.1 alpha arrays › Lipase chaperone LifO-like › Lipase chaperone LifO-like › Lipase chaperone LifO-like › Lipase_chap 0.62 47.0 3.18e-01 81.1% 36.3%
3930816 101.1.2.236 alpha arrays › HTH › HTH › winged helix domain › POLR3C_WHD 0.60 47.0 3.18e-01 85.1% 23.6%
1447882 148.1.3.28 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_11 0.60 38.0 2.90e-01 89.2% 25.4%
5001060 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.59 39.0 3.90e-01 93.2% 65.4%
3717640 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.59 46.0 3.48e-01 87.8% 41.0%
3202976 7023.1.1.0 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein 0.59 46.0 3.63e-01 89.2% 57.1%
3574981 604.12.1.91 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › RSLD_CPSF6 0.58 43.0 4.47e-01 98.6% 87.1%
3181590 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.58 37.0 3.62e-01 81.1% 58.7%
3976109 632.7.1.61 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › BREX_BrxC_helical 0.57 39.0 3.52e-01 70.3% 56.2%
4985660 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.57 40.0 2.96e-01 95.9% 27.1%
4958049 4204.1.1.5 alpha bundles › AF0941-like › AF0941-like › AF0941-like › DUF2150 0.57 49.0 4.38e-01 100.0% 79.1%
4623986 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 41.0 2.89e-01 77.0% 23.6%
3229748 1134.1.1.9 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › RSLD_CPSF6 0.57 43.0 4.19e-01 98.6% 74.1%
2075049 3787.1.1.0 alpha bundles › HAD superfamily helical bundle insertion domain 0.56 37.0 3.62e-01 70.3% 100.0%
4960347 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.55 37.0 3.46e-01 70.3% 83.2%
3958924 4033.1.1.0 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like 0.55 40.0 3.84e-01 89.2% 65.6%
3423943 1128.1.1.2 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 0.53 34.0 3.33e-01 82.4% 57.5%
3403227 192.8.1.465 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CHD5 0.52 36.0 3.24e-01 87.8% 49.1%
4960526 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.52 41.0 4.00e-01 85.1% 93.8%
3526105 604.3.1.18 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF27519 0.52 41.0 3.87e-01 87.8% 72.2%
3770066 3291.1.1.169 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th 0.52 38.0 2.86e-01 86.5% 29.7%
3995535 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 36.0 3.58e-01 100.0% 70.0%
5005257 2.21.1.0 beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.51 37.0 2.91e-01 77.0% 82.9%
3352169 109.4.1.1296 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long, TPR_24 0.51 36.0 2.62e-01 100.0% 24.3%