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p3a

Euk-Vir

Grapevine_Cabernet_Sauvignon_reovirus

p3a__YP_009163945__Grapevine_Cabernet_Sauvignon_reovirus__1640277

Identity

Accession:: YP_009163945 ↗
Protein ID:: p3a
Kingdom:: euk

Quality

74.9 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Grapevine_Cabernet_Sauvignon_reovirus

TaxID: 1640277

Cluster

View cluster (29 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1087-1185

PDB

D2 medium residues 38-63_145-176_212-246_760-798

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase_P3a__YP_003934919__Raspberry_latent_virus__907191__D31-61_142-182_199-247

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22209.2 best	CPV_RdRP_N	50.7	2.40e-13	35.6%	16.1%

D3 medium residues 64-144_177-211

PDB

Domain cluster: representative

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22209.2 best	CPV_RdRP_N	82.7	4.00e-23	69.8%	31.1%
PF22209.2	CPV_RdRP_N	38.1	1.70e-09	30.2%	14.5%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1697856	4963.1.1.3 ↗	alpha complex topology › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › CPV_RdRP_N	0.84	79.0	5.49e-01	100.0%	42.4%
3415346	6039.1.1.1 ↗	few secondary structure elements › CLIP domain › CLIP domain › CLIP domain › CLIP	0.52	29.0	3.56e-01	75.0%	92.3%

D4 medium residues 247-343

PDB

Domain cluster: rep: RNA-dependent_RNA_polymerase_P3a__YP_003934919__Raspberry_latent_virus__907191__D248-343

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22209.2 best	CPV_RdRP_N	78.6	7.20e-22	72.2%	28.2%

D5 medium residues 344-396_471-497_557-610_624-660

PDB

Domain cluster: representative

Pfam (3)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22212.2 best	CPV_RdRP_pol_dom	88.8	4.10e-25	54.4%	25.8%
PF22212.2	CPV_RdRP_pol_dom	34.0	1.90e-08	30.4%	13.3%
PF22212.2	CPV_RdRP_pol_dom	32.6	4.80e-08	17.0%	7.0%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2r7rA05	1.10.357.80	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.52	46.0	4.60e-01	94.2%	100.0%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1697857	304.48.1.30 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › CPV_RdRP_pol_dom	0.86	81.0	6.24e-01	98.2%	80.9%

D6 medium residues 397-470_498-514

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22212.2 best	CPV_RdRP_pol_dom	80.9	1.00e-22	82.4%	19.8%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2hzdA00	6.10.20.40	Special › Helix non-globular › Arc Repressor Mutant, subunit A › TEA/ATTS domain	0.58	30.0	3.18e-01	100.0%	53.7%
1iuqA01	1.10.1200.50	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal	0.53	31.0	3.38e-01	100.0%	68.4%
2n00A00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.52	35.0	3.53e-01	70.3%	96.8%
1wteB01	1.10.3250.10	Mainly Alpha › Orthogonal Bundle › type ii restriction endonuclease, domain 1 › type ii restriction endonuclease, domain 1	0.51	37.0	3.22e-01	100.0%	48.3%

D7 medium residues 515-556_661-759

PDB

Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22212.2 best	CPV_RdRP_pol_dom	65.9	3.60e-18	48.2%	17.9%
PF22212.2	CPV_RdRP_pol_dom	62.8	3.20e-17	31.9%	11.7%

D8 medium residues 799-850_924-935_1022-1068

PDB