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papain-like_protease

Euk-Vir

Cucurbit_yellow_stunting_disorder_virus

papain-like_protease__NP_851779__Cucurbit_yellow_stunting_disorder_virus__51330

Identity

Accession:
NP_851779 ↗
Protein ID:
papain-like_protease
Kingdom:
euk

Quality

70.6 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Closteroviridae› Crinivirus› Cucurbit_yellow_stunting_disorder_virus

TaxID: 51330

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 70-148
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1li5B01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 48.0 3.35e-01 87.3% 76.2%
4rayA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.59 33.0 3.91e-01 77.2% 82.0%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.56 32.0 3.69e-01 88.6% 78.9%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.53 46.0 3.38e-01 100.0% 47.2%
1z1bA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.52 31.0 3.53e-01 100.0% 82.5%
2ff4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 36.0 3.35e-01 73.4% 69.7%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.51 27.0 2.63e-01 78.5% 44.4%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3373091 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.60 27.0 3.29e-01 93.7% 64.0%
3626178 592.7.1.1 ↗ alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain › GIPC1_GH2 0.60 34.0 3.26e-01 98.7% 46.7%
3291533 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.58 30.0 2.97e-01 93.7% 44.7%
4282188 5059.1.1.59 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EmrE 0.54 44.0 3.03e-01 93.7% 56.8%
4278298 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.52 36.0 3.17e-01 74.7% 94.1%
3989311 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.52 36.0 3.16e-01 73.4% 90.8%
3210148 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 41.0 2.91e-01 88.6% 67.2%
3469215 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.51 37.0 2.35e-01 77.2% 33.8%
4217023 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 40.0 3.18e-01 87.3% 91.1%
5035582 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.51 33.0 2.97e-01 94.9% 46.1%
3177693 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 43.0 2.76e-01 92.4% 20.8%
4024189 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 41.0 3.81e-01 98.7% 68.2%
4520165 5054.1.1.7 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › KdpA 0.50 42.0 2.65e-01 98.7% 24.9%
4969735 7584.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins 0.50 40.0 3.14e-01 88.6% 95.0%
D2 high residues 162-301
PDB
Domain cluster: rep: papain-like_protease__YP_001816797__Bean_yellow_disorder_virus__267970__D171-308
D3 medium residues 313-389
PDB
Domain cluster: representative
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5cbeE00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.68 39.0 4.27e-01 85.7% 68.8%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.66 45.0 4.52e-01 71.4% 97.5%
1e0bA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.65 39.0 4.32e-01 81.8% 75.4%
6g9sA01 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.64 44.0 2.88e-01 71.4% 66.6%
1a15A00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.64 36.0 3.84e-01 83.1% 62.7%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.62 53.0 4.38e-01 96.1% 98.6%
2czoA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.61 37.0 3.17e-01 87.0% 36.2%
5lvxC02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.61 41.0 3.68e-01 96.1% 49.1%
3d9wA02 2.40.128.150 Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases 0.61 47.0 4.29e-01 83.1% 96.1%
3pcrA01 3.10.450.460 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain 0.60 41.0 3.83e-01 94.8% 57.4%
4obiA00 2.60.320.10 Mainly Beta › Sandwich › mini-chromosome maintenance (MCM) complex, domain 2 › N-utilization substance G protein NusG, insert domain 0.59 45.0 4.41e-01 93.5% 74.7%
2k7iA01 3.30.160.160 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YegP-like 0.59 33.0 4.06e-01 81.8% 89.6%
7obmA01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.58 51.0 3.40e-01 100.0% 52.6%
3u12A00 2.30.29.180 Mainly Beta › Roll › PH-domain like › Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain 0.56 46.0 4.19e-01 90.9% 98.1%
4qxaB00 2.30.29.230 Mainly Beta › Roll › PH-domain like › 0.56 48.0 4.00e-01 100.0% 89.8%
1ci3M02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.56 37.0 4.20e-01 79.2% 91.4%
3blcA00 2.70.98.90 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.55 48.0 3.33e-01 100.0% 84.3%
1iwmA00 2.50.20.10 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX 0.55 48.0 3.68e-01 97.4% 68.4%
1jv2B04 4.10.1240.30 Few Secondary Structures › Irregular › Hormone receptor fold › 0.55 31.0 2.99e-01 79.2% 47.7%
3dpuB03 3.30.310.200 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.55 38.0 3.44e-01 93.5% 51.9%
3flpA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 48.0 3.50e-01 100.0% 66.8%
4e4fA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.54 41.0 3.39e-01 81.8% 58.2%
1ecsA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 33.0 2.89e-01 84.4% 40.0%
1ospO02 3.90.930.1 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › 0.54 46.0 3.86e-01 100.0% 70.5%
6muwH00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 47.0 3.53e-01 100.0% 61.7%
1rypL00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 47.0 3.47e-01 100.0% 58.0%
3n4eA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.54 41.0 3.74e-01 81.8% 79.8%
1ryp200 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 47.0 3.38e-01 100.0% 57.1%
3h5kA01 3.40.420.10 Alpha Beta › 3-Layer(aba) Sandwich › Ricin (A subunit); domain 1 › Ricin (A subunit), domain 1 0.53 42.0 3.31e-01 88.3% 61.0%
3qv0A00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.53 45.0 3.50e-01 96.1% 64.2%
3unbF00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.53 46.0 3.31e-01 100.0% 52.0%
1iucA00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.53 46.0 3.11e-01 100.0% 57.7%
2wtzA02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.53 41.0 2.93e-01 84.4% 32.1%
2p4oA01 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.53 44.0 3.08e-01 97.4% 54.8%
6muwK00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.53 46.0 3.47e-01 100.0% 61.5%
4za3A01 3.40.420.10 Alpha Beta › 3-Layer(aba) Sandwich › Ricin (A subunit); domain 1 › Ricin (A subunit), domain 1 0.52 41.0 3.32e-01 88.3% 62.6%
2vrqA01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 46.0 3.81e-01 96.1% 79.5%
1rypC00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.52 46.0 3.27e-01 100.0% 51.2%
2gfaB01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.52 35.0 3.87e-01 70.1% 93.5%
1gqyB02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.52 41.0 3.04e-01 87.0% 43.3%
5fmgG00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.52 45.0 3.32e-01 100.0% 57.5%
1rypA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.52 45.0 3.23e-01 100.0% 55.1%
6htnA01 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.52 45.0 3.77e-01 98.7% 64.2%
3f1jA00 2.70.20.40 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Borna disease virus, matrix protein 0.51 38.0 3.08e-01 76.6% 70.0%
4ozuA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 45.0 2.96e-01 100.0% 47.3%
2y24A01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.51 44.0 3.95e-01 96.1% 77.6%
4hgzA02 2.20.25.570 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.51 33.0 3.60e-01 90.9% 85.0%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3940690 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.68 34.0 3.05e-01 79.2% 33.3%
4929797 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.68 47.0 5.22e-01 72.7% 98.3%
3673266 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.67 36.0 3.50e-01 70.1% 48.2%
5039633 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.66 39.0 4.06e-01 93.5% 62.2%
3790904 4.8.1.2 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo_shadow 0.65 39.0 4.29e-01 81.8% 75.0%
5012193 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 48.0 3.54e-01 96.1% 30.5%
1097232 3180.1.1.1 ↗ a+b two layers › LEE-encoded effector EspG N-terminal domain-related › LEE-encoded effector EspG N-terminal domain-related › LEE-encoded effector EspG N-terminal domain-related › EspG 0.62 43.0 3.86e-01 96.1% 52.3%
5002402 3153.1.1.0 ↗ a+b two layers › PipX › PipX › PipX 0.62 43.0 4.42e-01 97.4% 74.7%
4003932 292.2.1.0 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.61 49.0 4.18e-01 100.0% 55.0%
4349950 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.60 40.0 4.50e-01 72.7% 88.3%
None — 0.60 38.0 4.05e-01 93.5% 74.6%
3585414 292.2.1.0 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.59 47.0 4.24e-01 100.0% 60.9%
3937390 2484.8.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) 0.59 47.0 3.33e-01 88.3% 88.6%
3721633 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.59 38.0 3.79e-01 92.2% 62.5%
3505083 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.59 51.0 3.34e-01 98.7% 42.0%
3364428 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.59 52.0 3.77e-01 100.0% 68.2%
4119875 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.58 40.0 4.30e-01 85.7% 84.6%
3699568 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.58 40.0 4.14e-01 71.4% 92.9%
3989851 11.1.1.1339 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CFSR 0.57 47.0 3.85e-01 90.9% 65.5%
5044642 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.57 44.0 3.18e-01 87.0% 58.8%
5041549 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 50.0 3.44e-01 100.0% 69.1%
5022797 12.6.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related 0.56 51.0 3.69e-01 100.0% 69.8%
3958695 3484.1.1.2 ↗ a+b two layers › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Glyco_hydro_64 0.56 50.0 3.95e-01 100.0% 61.3%
4195627 4.6.1.6 ↗ beta barrels › SH3 › PRC-barrel domain › PRC-barrel domain › PRC_RimM 0.56 40.0 4.34e-01 77.9% 89.2%
4206684 4.6.1.6 ↗ beta barrels › SH3 › PRC-barrel domain › PRC-barrel domain › PRC_RimM 0.55 42.0 4.53e-01 84.4% 95.4%
3891230 5.1.5.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WDR93 0.55 48.0 2.94e-01 100.0% 48.7%
3989855 706.2.1.8 ↗ beta complex topology › Head domain of nucleotide exchange factor GrpE › G5 and E repeats in surface protein G › G5 and E repeats in surface protein G › CFSR 0.55 40.0 4.16e-01 77.9% 84.3%
3979396 3454.1.1.4 ↗ beta barrels › GspC HR domain/PilP-like › GspC HR domain/PilP-like › GspC HR domain/PilP-like › HofP 0.55 41.0 4.09e-01 88.3% 77.5%
3891571 5.1.7.2 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 10-bladed › Sortilin-Vps10 0.54 48.0 3.02e-01 100.0% 24.0%
3912770 5.1.7.2 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 10-bladed › Sortilin-Vps10 0.54 47.0 2.85e-01 100.0% 22.7%
3191760 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.53 46.0 3.28e-01 100.0% 57.7%
3766842 5.1.5.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WDR93 0.53 46.0 2.84e-01 100.0% 48.2%
3477683 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.53 46.0 3.14e-01 100.0% 70.3%
4266498 218.1.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.53 41.0 3.81e-01 81.8% 86.3%
3846506 5.1.4.148 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WDR93 0.53 48.0 2.89e-01 100.0% 31.2%
3605064 5.1.4.74 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Vps16_N 0.53 47.0 2.88e-01 100.0% 27.0%
3472026 220.1.1.27 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_RBD 0.53 44.0 3.94e-01 100.0% 96.7%
4029837 5.1.4.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,CAF1C_H4-bd 0.52 46.0 2.95e-01 100.0% 38.4%
5016556 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 45.0 4.33e-01 100.0% 87.8%
4017301 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.52 44.0 3.79e-01 96.1% 77.6%
2491332 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.51 42.0 3.70e-01 96.1% 91.3%
3717566 5.1.3.28 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 0.51 44.0 3.11e-01 100.0% 87.1%
3213868 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.51 42.0 3.56e-01 93.5% 85.2%
2801888 12.1.1.24 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Malt_amylase_C 0.51 40.0 4.08e-01 85.7% 98.7%
4104221 5.1.7.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 10-bladed › BNR, Sortilin-Vps10 0.50 42.0 2.67e-01 100.0% 23.9%
D4 medium residues 390-461
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rnvA00 3.90.70.150 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Helper component proteinase 0.72 64.0 5.36e-01 100.0% 95.9%
3daxB00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 41.0 2.55e-01 84.7% 82.1%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5019790 206.1.3.117 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PEP-utilizers_C 0.50 37.0 2.18e-01 81.9% 9.9%