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pig_ID_2419_F67_scaffold_44_curated_prodigal-single.1__X__X__00119
Bact-Virpig_ID_2419_F67_scaffold_44_curated_prodigal-single.1__X__X__00119
Identity
- Kingdom:
- phage
Quality
94.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 119-208
Domain cluster:
representative
CATH (84)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.90 | 84.0 | 6.80e-01 | 100.0% | 60.4% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.89 | 69.0 | 6.74e-01 | 95.6% | 74.5% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.87 | 81.0 | 6.54e-01 | 100.0% | 67.7% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.85 | 74.0 | 6.37e-01 | 100.0% | 62.4% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.85 | 65.0 | 6.94e-01 | 100.0% | 93.5% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.84 | 67.0 | 6.28e-01 | 100.0% | 70.8% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.84 | 72.0 | 4.76e-01 | 100.0% | 25.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.84 | 73.0 | 6.33e-01 | 93.3% | 68.4% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.83 | 76.0 | 5.58e-01 | 100.0% | 39.9% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.83 | 78.0 | 6.27e-01 | 100.0% | 79.5% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.83 | 64.0 | 6.99e-01 | 90.0% | 100.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.82 | 75.0 | 5.46e-01 | 100.0% | 43.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 62.0 | 5.53e-01 | 100.0% | 57.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 62.0 | 5.80e-01 | 100.0% | 66.4% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.81 | 75.0 | 5.72e-01 | 100.0% | 57.4% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.81 | 54.0 | 5.48e-01 | 94.4% | 70.1% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 61.0 | 6.47e-01 | 100.0% | 88.9% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 72.0 | 5.39e-01 | 96.7% | 72.2% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 67.0 | 6.51e-01 | 100.0% | 81.0% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.80 | 72.0 | 5.16e-01 | 100.0% | 34.9% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.80 | 73.0 | 6.09e-01 | 100.0% | 70.2% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.80 | 63.0 | 6.70e-01 | 100.0% | 98.7% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 70.0 | 5.95e-01 | 97.8% | 60.6% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.80 | 53.0 | 6.24e-01 | 72.2% | 95.4% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.79 | 57.0 | 6.35e-01 | 81.1% | 100.0% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.79 | 71.0 | 4.84e-01 | 100.0% | 28.7% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.79 | 73.0 | 5.90e-01 | 100.0% | 55.9% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.79 | 68.0 | 7.01e-01 | 96.7% | 98.8% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 69.0 | 4.99e-01 | 100.0% | 35.5% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.79 | 60.0 | 6.54e-01 | 90.0% | 100.0% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 72.0 | 5.35e-01 | 100.0% | 50.7% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.78 | 57.0 | 5.38e-01 | 96.7% | 65.1% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.77 | 58.0 | 6.34e-01 | 100.0% | 100.0% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.77 | 70.0 | 5.26e-01 | 100.0% | 100.0% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 69.0 | 5.13e-01 | 100.0% | 72.5% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.77 | 52.0 | 5.98e-01 | 96.7% | 98.4% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 68.0 | 5.77e-01 | 97.8% | 61.9% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 60.0 | 5.86e-01 | 98.9% | 76.8% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 58.0 | 6.29e-01 | 83.3% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 69.0 | 5.51e-01 | 100.0% | 54.3% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 65.0 | 6.03e-01 | 90.0% | 82.6% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 69.0 | 5.46e-01 | 100.0% | 50.3% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 66.0 | 5.44e-01 | 100.0% | 53.0% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 67.0 | 6.61e-01 | 98.9% | 95.7% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 59.0 | 5.55e-01 | 100.0% | 69.1% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 66.0 | 6.34e-01 | 95.6% | 92.2% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 66.0 | 5.02e-01 | 98.9% | 51.4% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.74 | 51.0 | 5.77e-01 | 76.7% | 100.0% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 64.0 | 5.77e-01 | 93.3% | 72.5% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 64.0 | 6.50e-01 | 100.0% | 97.7% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 67.0 | 4.83e-01 | 100.0% | 50.4% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 55.0 | 5.86e-01 | 84.4% | 92.2% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.74 | 61.0 | 6.37e-01 | 92.2% | 100.0% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.73 | 50.0 | 5.72e-01 | 71.1% | 100.0% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.73 | 54.0 | 5.73e-01 | 98.9% | 88.5% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 50.0 | 5.79e-01 | 75.6% | 100.0% |
| 3ajwA00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 63.0 | 5.56e-01 | 100.0% | 64.9% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.73 | 67.0 | 4.48e-01 | 100.0% | 52.4% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 56.0 | 5.75e-01 | 83.3% | 86.0% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 65.0 | 5.62e-01 | 100.0% | 64.7% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 54.0 | 5.49e-01 | 100.0% | 80.0% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 54.0 | 5.46e-01 | 77.8% | 81.8% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.72 | 61.0 | 4.81e-01 | 94.4% | 45.2% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.72 | 65.0 | 6.34e-01 | 98.9% | 100.0% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 65.0 | 5.08e-01 | 100.0% | 47.9% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.71 | 62.0 | 5.98e-01 | 97.8% | 83.5% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.71 | 63.0 | 6.41e-01 | 98.9% | 98.9% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 57.0 | 5.51e-01 | 97.8% | 78.4% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 53.0 | 5.71e-01 | 86.7% | 100.0% |
| 4akgA11 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.69 | 56.0 | 3.98e-01 | 87.8% | 46.0% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 60.0 | 4.65e-01 | 96.7% | 63.3% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.68 | 59.0 | 5.49e-01 | 97.8% | 83.3% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.68 | 62.0 | 5.70e-01 | 100.0% | 77.4% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 57.0 | 5.47e-01 | 96.7% | 79.4% |
| 4cgkA01 | 6.10.250.3150 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 60.0 | 4.58e-01 | 100.0% | 43.0% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.67 | 53.0 | 5.75e-01 | 95.6% | 98.7% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.67 | 60.0 | 4.42e-01 | 100.0% | 57.0% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 58.0 | 4.02e-01 | 98.9% | 29.4% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.65 | 57.0 | 4.57e-01 | 98.9% | 95.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.65 | 45.0 | 4.26e-01 | 72.2% | 59.1% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 49.0 | 4.69e-01 | 93.3% | 73.4% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.62 | 43.0 | 4.40e-01 | 75.6% | 74.2% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 46.0 | 4.05e-01 | 78.9% | 73.1% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 55.0 | 5.33e-01 | 100.0% | 98.0% |
ECOD (85)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3196934 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.89 | 80.0 | 6.54e-01 | 100.0% | 55.5% |
| 3870151 | 3755.3.1.9 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 | 0.86 | 80.0 | 6.99e-01 | 100.0% | 75.4% |
| 5040840 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.82 | 76.0 | 4.42e-01 | 100.0% | 12.9% |
| 3559082 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 74.0 | 5.75e-01 | 100.0% | 47.8% |
| 3364696 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.82 | 69.0 | 5.64e-01 | 88.9% | 51.6% |
| 3207855 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 76.0 | 6.30e-01 | 100.0% | 74.0% |
| 3366371 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 74.0 | 5.22e-01 | 100.0% | 45.2% |
| 4022925 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 75.0 | 5.61e-01 | 100.0% | 59.5% |
| 5057329 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 65.0 | 5.45e-01 | 100.0% | 52.4% |
| 5062668 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.81 | 75.0 | 6.63e-01 | 100.0% | 72.0% |
| 4996626 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 75.0 | 5.29e-01 | 100.0% | 54.5% |
| 3282651 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.81 | 72.0 | 4.43e-01 | 98.9% | 17.1% |
| 3699472 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 73.0 | 4.51e-01 | 100.0% | 17.8% |
| 4982498 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.80 | 74.0 | 4.40e-01 | 100.0% | 34.6% |
| 3611166 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 73.0 | 5.55e-01 | 100.0% | 80.0% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 69.0 | 6.41e-01 | 96.7% | 85.2% |
| 4324499 | 3755.1.1.3 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM | 0.79 | 71.0 | 6.09e-01 | 100.0% | 64.8% |
| 3704098 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 73.0 | 5.84e-01 | 100.0% | 54.7% |
| 4606154 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 72.0 | 5.73e-01 | 97.8% | 76.5% |
| 3598781 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.79 | 71.0 | 4.94e-01 | 100.0% | 31.0% |
| 2512818 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.79 | 73.0 | 5.14e-01 | 100.0% | 34.7% |
| 3495507 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 73.0 | 5.86e-01 | 100.0% | 87.3% |
| 3988263 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 71.0 | 5.62e-01 | 100.0% | 50.3% |
| 5074535 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 71.0 | 6.48e-01 | 100.0% | 84.2% |
| 3693339 | 3922.1.1.228 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › LisH | 0.79 | 71.0 | 5.62e-01 | 100.0% | 50.0% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 70.0 | 5.07e-01 | 100.0% | 74.8% |
| 4028451 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.78 | 68.0 | 6.04e-01 | 100.0% | 68.0% |
| 4559671 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.78 | 71.0 | 4.12e-01 | 100.0% | 11.4% |
| 4177363 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 72.0 | 6.06e-01 | 100.0% | 66.9% |
| 3699468 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 70.0 | 5.40e-01 | 100.0% | 45.0% |
| 4276314 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 70.0 | 5.25e-01 | 100.0% | 40.9% |
| 4950734 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.78 | 71.0 | 5.50e-01 | 100.0% | 85.8% |
| 3599997 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.78 | 72.0 | 4.07e-01 | 100.0% | 65.2% |
| 3240634 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 72.0 | 5.90e-01 | 100.0% | 58.1% |
| 4028552 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 71.0 | 5.10e-01 | 100.0% | 39.6% |
| 3168460 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.77 | 70.0 | 4.06e-01 | 100.0% | 57.9% |
| 3825615 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.77 | 70.0 | 4.00e-01 | 100.0% | 68.5% |
| 3770253 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 70.0 | 5.49e-01 | 100.0% | 92.4% |
| 3554294 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.77 | 70.0 | 5.36e-01 | 100.0% | 63.5% |
| 3889547 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 68.0 | 5.38e-01 | 100.0% | 53.2% |
| 4259085 | 3755.4.1.66 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal | 0.77 | 69.0 | 4.80e-01 | 100.0% | 91.7% |
| 4943562 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 70.0 | 5.31e-01 | 100.0% | 43.9% |
| 3642640 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.76 | 70.0 | 4.76e-01 | 100.0% | 93.5% |
| 3512620 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.76 | 70.0 | 5.74e-01 | 100.0% | 56.2% |
| 4310983 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.76 | 68.0 | 4.12e-01 | 100.0% | 20.1% |
| 3418796 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.76 | 69.0 | 5.31e-01 | 100.0% | 58.8% |
| 4405271 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.76 | 68.0 | 5.72e-01 | 100.0% | 58.1% |
| 4001186 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.76 | 68.0 | 5.35e-01 | 100.0% | 60.5% |
| 3634628 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.76 | 69.0 | 4.45e-01 | 100.0% | 25.4% |
| 3764842 | 209.1.1.1 ↗ | a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C | 0.76 | 68.0 | 4.69e-01 | 100.0% | 35.1% |
| 3706526 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.76 | 66.0 | 5.59e-01 | 100.0% | 58.0% |
| 149872 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.76 | 59.0 | 6.27e-01 | 100.0% | 96.2% |
| 3623410 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.76 | 69.0 | 4.20e-01 | 100.0% | 17.6% |
| 4220356 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.76 | 69.0 | 4.61e-01 | 100.0% | 78.8% |
| 3165834 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.76 | 70.0 | 4.93e-01 | 100.0% | 71.2% |
| 4604091 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.76 | 68.0 | 6.57e-01 | 97.8% | 98.0% |
| 4969098 | 3926.1.1.0 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D | 0.75 | 68.0 | 5.42e-01 | 98.9% | 73.1% |
| 3970019 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.75 | 70.0 | 5.07e-01 | 100.0% | 39.1% |
| 3919840 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.75 | 67.0 | 5.06e-01 | 100.0% | 80.0% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.75 | 68.0 | 5.61e-01 | 100.0% | 56.2% |
| 3350514 | 3922.1.1.145 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › KIF21A_4th | 0.75 | 64.0 | 5.35e-01 | 100.0% | 53.8% |
| 3916825 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 69.0 | 5.76e-01 | 100.0% | 70.0% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.75 | 67.0 | 4.13e-01 | 100.0% | 42.4% |
| 3318812 | 192.8.1.248 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th | 0.75 | 68.0 | 5.69e-01 | 98.9% | 97.3% |
| 4260979 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 66.0 | 4.70e-01 | 100.0% | 33.2% |
| 4374392 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.75 | 66.0 | 4.33e-01 | 100.0% | 23.1% |
| 3694749 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 66.0 | 4.78e-01 | 100.0% | 42.4% |
| 4026040 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.74 | 66.0 | 4.06e-01 | 100.0% | 42.3% |
| 4392833 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 66.0 | 5.00e-01 | 100.0% | 54.0% |
| 3412171 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.74 | 65.0 | 4.03e-01 | 100.0% | 42.6% |
| 4992667 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 65.0 | 4.64e-01 | 100.0% | 41.8% |
| 4941675 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.73 | 65.0 | 4.10e-01 | 100.0% | 21.2% |
| 3598025 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.73 | 67.0 | 5.36e-01 | 100.0% | 52.9% |
| 4471073 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.72 | 67.0 | 4.34e-01 | 100.0% | 59.7% |
| 4024356 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 65.0 | 5.35e-01 | 100.0% | 58.7% |
| 3176480 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.72 | 64.0 | 6.52e-01 | 98.9% | 100.0% |
| 3361164 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.72 | 64.0 | 4.91e-01 | 100.0% | 90.2% |
| 3337008 | 192.2.1.60 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th | 0.71 | 61.0 | 5.35e-01 | 98.9% | 62.9% |
| 4345467 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.71 | 64.0 | 4.03e-01 | 100.0% | 19.8% |
| 4038138 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.70 | 64.0 | 5.64e-01 | 100.0% | 73.8% |
| 3965792 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.70 | 60.0 | 4.28e-01 | 95.6% | 100.0% |
| 3896917 | 207.1.1.24 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_8 | 0.70 | 61.0 | 4.17e-01 | 98.9% | 30.9% |
| 4282125 | 3755.3.1.295 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › WWC1 | 0.69 | 48.0 | 3.69e-01 | 74.4% | 31.7% |
| 3732397 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.69 | 61.0 | 5.59e-01 | 100.0% | 75.0% |
| 3829282 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 58.0 | 5.05e-01 | 98.9% | 91.9% |
D2
medium
residues 1-55
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01028.26 best | Topoisom_I | 39.8 | 4.70e-10 | 100.0% | 23.2% |
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a31A03 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.88 | 80.0 | 5.70e-01 | 100.0% | 37.3% |
| 1a41A01 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.70 | 58.0 | 4.56e-01 | 98.2% | 42.5% |
| 2h7fX02 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.68 | 56.0 | 3.75e-01 | 98.2% | 23.7% |
| 5jk0B01 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.62 | 51.0 | 3.71e-01 | 98.2% | 35.8% |
| 5x8tT00 | 3.90.470.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 | 0.60 | 35.0 | 2.62e-01 | 87.3% | 22.2% |
| 2vw9B00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.59 | 43.0 | 3.60e-01 | 81.8% | 81.9% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.58 | 42.0 | 3.57e-01 | 74.5% | 100.0% |
| 3buxB03 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.58 | 36.0 | 3.22e-01 | 81.8% | 39.5% |
| 1cp9A01 | 1.10.439.10 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 | 0.58 | 41.0 | 3.07e-01 | 76.4% | 63.7% |
| 1nh8A03 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 41.0 | 3.93e-01 | 81.8% | 86.6% |
| 4bgjA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.56 | 46.0 | 3.70e-01 | 96.4% | 72.0% |
| 5ek8A01 | 2.60.40.3330 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 39.0 | 3.03e-01 | 76.4% | 84.9% |
| 1xjkA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.54 | 42.0 | 2.51e-01 | 100.0% | 75.0% |
| 6tdxG01 | 3.40.1380.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit | 0.54 | 37.0 | 2.48e-01 | 72.7% | 67.3% |
| 4gs5A01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.54 | 43.0 | 2.97e-01 | 100.0% | 68.4% |
| 1ilvA00 | 3.40.1210.10 | Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase | 0.53 | 44.0 | 2.98e-01 | 100.0% | 82.9% |
| 2gukA00 | 3.30.2190.10 | Alpha Beta › 2-Layer Sandwich › PG1857-like › PG1857-like | 0.53 | 44.0 | 3.64e-01 | 100.0% | 52.3% |
| 3tcaA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 43.0 | 3.79e-01 | 96.4% | 100.0% |
| 3ihlB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 35.0 | 2.34e-01 | 70.9% | 55.9% |
| 2wyqA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 35.0 | 3.25e-01 | 74.5% | 93.5% |
| 6qdws00 | 3.90.470.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 | 0.51 | 34.0 | 2.79e-01 | 89.1% | 32.1% |
| 4wiwA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.51 | 38.0 | 3.52e-01 | 76.4% | 87.0% |
| 7trwA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 43.0 | 3.62e-01 | 98.2% | 58.4% |
| 3msyA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.51 | 43.0 | 3.56e-01 | 100.0% | 55.9% |
| 4a55A01 | 3.10.20.770 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.50 | 38.0 | 2.51e-01 | 90.9% | 21.0% |
| 4zg5A00 | 3.40.1210.10 | Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase | 0.50 | 41.0 | 2.80e-01 | 100.0% | 84.6% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3599060 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.88 | 80.0 | 5.29e-01 | 100.0% | 28.0% |
| 3886079 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.87 | 79.0 | 5.24e-01 | 100.0% | 27.3% |
| 3621756 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.87 | 79.0 | 5.77e-01 | 100.0% | 40.0% |
| 3960610 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 42.0 | 2.87e-01 | 76.4% | 17.2% |
| 3253068 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.63 | 43.0 | 3.84e-01 | 72.7% | 100.0% |
| 4357768 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.63 | 50.0 | 3.97e-01 | 96.4% | 45.4% |
| 3945241 | 2004.1.1.262 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF2813 | 0.62 | 42.0 | 2.96e-01 | 70.9% | 23.3% |
| 3248699 | 4232.1.1.1 ↗ | few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 | 0.61 | 44.0 | 3.58e-01 | 100.0% | 38.2% |
| 4210863 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.60 | 49.0 | 3.88e-01 | 98.2% | 48.5% |
| 3238035 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.60 | 41.0 | 4.21e-01 | 72.7% | 80.0% |
| 3638157 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.59 | 40.0 | 2.54e-01 | 70.9% | 18.1% |
| 4413773 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.59 | 47.0 | 3.74e-01 | 98.2% | 43.7% |
| 3508428 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 34.0 | 2.42e-01 | 83.6% | 17.8% |
| 4443502 | 109.4.1.116 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIH_assoc | 0.56 | 42.0 | 2.46e-01 | 85.5% | 9.9% |
| 3779781 | 109.4.1.1812 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RYDR_ITPR, RIH_assoc | 0.55 | 41.0 | 2.23e-01 | 83.6% | 5.0% |
| 3163963 | 3326.1.1.1 ↗ | alpha arrays › DNA-binding domain in UvrA › DNA-binding domain in UvrA › DNA-binding domain in UvrA › UvrA_DNA-bind | 0.54 | 39.0 | 3.32e-01 | 83.6% | 85.5% |
| 3622456 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.54 | 38.0 | 3.11e-01 | 74.5% | 90.9% |
| 5004912 | 3326.1.1.1 ↗ | alpha arrays › DNA-binding domain in UvrA › DNA-binding domain in UvrA › DNA-binding domain in UvrA › UvrA_DNA-bind | 0.53 | 39.0 | 3.26e-01 | 83.6% | 82.7% |
| 5056444 | 2002.1.1.29 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHDPS | 0.53 | 39.0 | 2.53e-01 | 85.5% | 93.6% |
| 3798928 | 59.1.4.2 ↗ | beta complex topology › triple barrel › triple barrel › TFIID subunits TAF1-TAF7 › DUF3591 | 0.53 | 42.0 | 2.53e-01 | 96.4% | 10.8% |
| 3626178 | 592.7.1.1 ↗ | alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain › GIPC1_GH2 | 0.53 | 40.0 | 3.50e-01 | 94.5% | 52.2% |
| 3950089 | 2011.2.1.1 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PNP_UDP_1 | 0.52 | 39.0 | 2.51e-01 | 81.8% | 83.6% |
| 3188358 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.52 | 37.0 | 2.27e-01 | 76.4% | 41.8% |
| 3998381 | 2004.1.1.432 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, Rad17 | 0.52 | 36.0 | 2.46e-01 | 76.4% | 65.3% |
| 4886572 | 3326.1.1.1 ↗ | alpha arrays › DNA-binding domain in UvrA › DNA-binding domain in UvrA › DNA-binding domain in UvrA › UvrA_DNA-bind | 0.52 | 36.0 | 2.80e-01 | 100.0% | 34.2% |
| 4411025 | 284.1.3.3 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › DUF4346 | 0.52 | 38.0 | 3.38e-01 | 83.6% | 55.0% |
| 3583670 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.51 | 41.0 | 2.98e-01 | 100.0% | 98.4% |
| 4928248 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 36.0 | 2.74e-01 | 74.5% | 76.9% |
| 3230369 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.50 | 39.0 | 2.49e-01 | 94.5% | 41.4% |
| 3487849 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.50 | 39.0 | 2.30e-01 | 85.5% | 37.9% |
D3
medium
residues 56-117_222-263
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01028.26 best | Topoisom_I | 31.7 | 1.40e-07 | 90.4% | 26.3% |
| PF14370.12 | Topo_C_assoc | 55.2 | 7.00e-15 | 76.9% | 60.0% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.88 | 79.0 | 6.44e-01 | 93.3% | 100.0% |
| 1a31A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.88 | 66.0 | 7.49e-01 | 82.7% | 100.0% |
| 2dofA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.58 | 37.0 | 4.04e-01 | 95.2% | 77.6% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.57 | 51.0 | 3.42e-01 | 100.0% | 75.7% |
| 3vibA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.58e-01 | 82.7% | 69.4% |
| 5u56A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 44.0 | 4.37e-01 | 86.5% | 100.0% |
| 4l8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 43.0 | 4.31e-01 | 88.5% | 100.0% |
| 4gyoB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 40.0 | 3.70e-01 | 82.7% | 87.1% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.52 | 39.0 | 4.08e-01 | 89.4% | 88.2% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5074319 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.94 | 77.0 | 7.81e-01 | 84.6% | 100.0% |
| 3352425 | 101.1.8.3 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I,Topo_C_assoc | 0.93 | 79.0 | 8.11e-01 | 87.5% | 100.0% |
| 4929147 | 101.1.8.5 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topo_C_assoc | 0.93 | 82.0 | 7.71e-01 | 91.3% | 100.0% |
| 3586327 | 101.1.8.5 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topo_C_assoc | 0.89 | 79.0 | 8.07e-01 | 91.3% | 100.0% |
| 3991144 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 43.0 | 4.64e-01 | 91.3% | 81.1% |
| 3436931 | 192.6.1.11 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › eIF-3c_N | 0.58 | 43.0 | 4.30e-01 | 79.8% | 100.0% |
| 3784455 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.58 | 46.0 | 4.00e-01 | 87.5% | 71.2% |
| 4142417 | 162.1.1.0 ↗ | alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD | 0.57 | 33.0 | 3.18e-01 | 92.3% | 48.3% |
| 4047303 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.55 | 43.0 | 4.34e-01 | 90.4% | 81.0% |
| 3290723 | 601.1.1.85 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PaaX_C | 0.54 | 44.0 | 4.42e-01 | 89.4% | 100.0% |
| 4978416 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.53 | 32.0 | 3.38e-01 | 96.2% | 65.3% |
| 3250524 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.53 | 39.0 | 3.21e-01 | 79.8% | 56.6% |
| 3227779 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.51 | 38.0 | 2.51e-01 | 80.8% | 22.4% |
| 3704156 | 283.1.1.1 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › Peptidase_M24 | 0.50 | 45.0 | 3.74e-01 | 100.0% | 98.9% |