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pol_polyprotein,_partial

Euk-Vir

Avian_leukemia_virus

pol_polyprotein,_partial__YP_004222728__Avian_leukemia_virus__11946

Identity

Accession:: YP_004222728 ↗
Protein ID:: pol_polyprotein,_partial
Kingdom:: euk

Quality

85.0 mean pLDDT

Cluster

View cluster (9 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 439-568

PDB

Domain cluster: rep: polyprotein__YP_002916057__Sweet_potato_badnavirus_B__647294__D493-623

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00075.31 best	RNase_H	32.0	1.90e-07	96.9%	93.6%

CATH (42)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1bqnA05	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.85	76.0	7.66e-01	100.0%	93.9%
2hb5A00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.82	78.0	7.40e-01	100.0%	87.3%
1f21A00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.81	74.0	6.99e-01	96.9%	89.5%
2qkbA00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.80	75.0	7.10e-01	98.5%	94.1%
2ehgA00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.79	72.0	6.84e-01	96.2%	86.6%
4e19A00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.77	71.0	7.09e-01	96.9%	94.7%
3u3gA00	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.77	71.0	6.91e-01	96.9%	93.6%
7oufB01	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.66	50.0	4.84e-01	94.6%	70.5%
7r8iA01	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.63	56.0	4.73e-01	97.7%	97.7%
1e8oA00	3.30.720.10	Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1	0.63	27.0	3.52e-01	76.9%	70.3%
3hrgA02	3.30.420.260	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, C-terminal domain	0.63	45.0	4.74e-01	92.3%	84.2%
4gniA03	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.60	39.0	4.60e-01	78.5%	98.9%
5fgoA00	3.10.450.700	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.59	27.0	3.73e-01	76.2%	88.7%
1hkgA02	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.58	45.0	4.53e-01	80.8%	97.7%
3wxmB02	3.30.420.60	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2	0.58	48.0	4.95e-01	88.5%	98.4%
2it1A03	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.57	21.0	2.92e-01	75.4%	63.9%
5d8nA01	3.40.220.10	Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1	0.57	45.0	4.03e-01	84.6%	86.2%
3agkA02	3.30.420.60	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2	0.57	47.0	4.87e-01	92.3%	94.4%
3d2fA03	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.57	37.0	4.18e-01	80.0%	91.4%
3hi0A02	3.30.420.150	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2	0.56	48.0	4.32e-01	94.6%	89.6%
4zi6C01	3.40.220.10	Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1	0.56	45.0	4.12e-01	85.4%	79.3%
3lm2A01	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.56	40.0	4.56e-01	83.1%	100.0%
1e5xA01	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.56	43.0	3.34e-01	81.5%	62.6%
2dmyA00	3.30.160.20	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain ›	0.56	29.0	3.35e-01	76.2%	67.0%
5m1pB00	3.30.420.240	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 ›	0.55	49.0	4.32e-01	96.9%	77.2%
3kqxL01	3.40.220.10	Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1	0.55	43.0	3.84e-01	83.8%	80.3%
4htlA01	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.55	40.0	4.47e-01	77.7%	100.0%
1iv0A00	3.30.420.140	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain	0.55	40.0	4.48e-01	84.6%	100.0%
1pjrA03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	41.0	3.58e-01	80.0%	83.5%
2o2gA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	45.0	3.84e-01	90.8%	83.3%
2nutB04	3.40.50.410	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain	0.54	44.0	3.64e-01	88.5%	99.6%
2eqmA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.54	21.0	3.02e-01	76.2%	77.4%
1okjB01	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.53	42.0	4.25e-01	90.0%	86.6%
3cssA00	3.40.50.1360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.53	41.0	3.33e-01	83.8%	95.5%
1vhxB00	3.30.420.140	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain	0.52	46.0	4.52e-01	94.6%	93.5%
2mjlA00	3.40.50.1470	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase	0.52	43.0	3.86e-01	93.1%	89.3%
4xr9B01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	43.0	3.75e-01	91.5%	95.3%
4qt4A00	3.40.50.1470	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase	0.52	42.0	3.80e-01	89.2%	91.0%
7essA01	3.30.420.140	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain	0.52	45.0	4.48e-01	93.1%	90.9%
4nurA03	3.30.1050.10	Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain	0.51	31.0	3.19e-01	89.2%	61.8%
2qmiA02	2.40.128.210	Mainly Beta › Beta Barrel › Lipocalin › Pab87 octamerisation domain	0.51	31.0	3.42e-01	82.3%	77.0%
2cfuA03	3.30.1050.10	Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain	0.50	31.0	3.19e-01	89.2%	62.8%

ECOD (90)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3526923	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.87	83.0	8.24e-01	99.2%	95.6%
1149588	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.87	83.0	7.52e-01	100.0%	89.1%
3828337	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.81	64.0	6.65e-01	82.3%	94.3%
3220656	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.81	76.0	5.48e-01	99.2%	43.7%
3355734	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.81	62.0	6.81e-01	80.0%	100.0%
4032398	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.80	72.0	7.21e-01	96.2%	93.8%
3878642	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.80	76.0	6.61e-01	100.0%	85.4%
4626944	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.80	72.0	7.34e-01	96.9%	98.4%
4969849	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.80	72.0	7.18e-01	95.4%	93.3%
5064572	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.80	73.0	7.35e-01	96.2%	96.2%
5041220	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.79	73.0	7.25e-01	96.9%	94.8%
4947486	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.79	71.0	7.07e-01	94.6%	94.8%
5073342	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.79	66.0	7.09e-01	93.1%	100.0%
5035771	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.79	72.0	7.29e-01	96.9%	96.2%
3935434	2484.5.1.2 ↗	mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH	0.79	63.0	6.39e-01	83.8%	88.5%
3590547	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.79	71.0	7.19e-01	96.2%	95.4%
3302604	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.79	72.0	6.49e-01	98.5%	73.5%
3629019	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.98e-01	96.2%	95.7%
4967986	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.78	67.0	6.09e-01	89.2%	83.0%
3220657	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.78	71.0	7.16e-01	95.4%	96.9%
3296387	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	73.0	6.60e-01	98.5%	76.3%
3454314	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	60.0	6.31e-01	80.0%	95.8%
3370997	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	73.0	7.03e-01	99.2%	97.2%
5075022	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	71.0	7.18e-01	96.2%	97.7%
3650067	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	73.0	6.73e-01	98.5%	80.6%
3218178	2484.1.1.4 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H	0.78	73.0	6.92e-01	98.5%	88.0%
3833907	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.85e-01	98.5%	84.7%
3337523	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.61e-01	98.5%	80.0%
3444879	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	73.0	6.90e-01	99.2%	85.3%
5079226	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	71.0	5.98e-01	96.2%	64.9%
3815341	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.91e-01	96.9%	87.5%
3304580	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.69e-01	99.2%	80.0%
3958207	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.78	72.0	6.98e-01	96.9%	90.7%
3651277	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	72.0	6.64e-01	98.5%	80.4%
3355790	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.78	71.0	7.02e-01	96.2%	93.3%
3997819	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.77	73.0	6.59e-01	100.0%	83.5%
3377418	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	69.0	6.56e-01	95.4%	82.0%
3932764	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.77	71.0	6.87e-01	98.5%	95.9%
3808254	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	70.0	6.58e-01	96.9%	80.6%
3324497	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	62.0	6.64e-01	89.2%	95.7%
3459933	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	71.0	6.52e-01	98.5%	78.2%
3300901	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	70.0	6.51e-01	98.5%	78.8%
3379842	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	69.0	6.75e-01	97.7%	88.6%
4985543	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	68.0	6.92e-01	95.4%	93.8%
3834310	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	72.0	6.87e-01	100.0%	90.0%
3257339	2484.1.1.212 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RT_RNaseH	0.77	70.0	7.14e-01	98.5%	100.0%
3666401	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.77	71.0	6.23e-01	98.5%	70.3%
3797946	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.77	71.0	6.91e-01	97.7%	95.7%
3317463	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	69.0	6.64e-01	95.4%	91.0%
3314391	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	68.0	6.44e-01	93.8%	82.0%
3458417	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	71.0	6.55e-01	98.5%	80.6%
3480829	2484.5.1.2 ↗	mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH	0.76	66.0	6.74e-01	93.8%	94.4%
3418019	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	71.0	6.53e-01	98.5%	80.6%
3422969	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	62.0	6.53e-01	88.5%	94.1%
2814146	896.1.1.1 ↗	a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Ribosomal_L38e	0.76	36.0	4.58e-01	83.8%	76.3%
3343216	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.76	61.0	6.37e-01	89.2%	91.7%
3806227	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	70.0	6.46e-01	98.5%	80.0%
3936714	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	69.0	6.69e-01	97.7%	88.3%
3830251	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	70.0	6.31e-01	98.5%	75.3%
3353667	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	68.0	6.52e-01	95.4%	94.5%
3803688	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	69.0	6.47e-01	97.7%	89.0%
3804102	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	69.0	6.42e-01	98.5%	80.0%
3802664	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.75	69.0	6.48e-01	99.2%	82.6%
3940020	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.75	65.0	6.55e-01	91.5%	98.5%
3819047	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	67.0	6.55e-01	95.4%	94.3%
3369743	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	61.0	5.88e-01	98.5%	77.1%
3452368	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	69.0	6.10e-01	98.5%	72.2%
3319380	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	49.0	5.26e-01	70.0%	78.2%
3507332	2484.5.1.2 ↗	mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH	0.74	68.0	6.62e-01	96.9%	90.0%
3459975	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	62.0	6.28e-01	88.5%	93.8%
3417357	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.74	69.0	6.27e-01	98.5%	78.2%
3300995	2484.1.1.67 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3	0.73	65.0	6.45e-01	93.8%	92.6%
3937352	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.71	54.0	5.70e-01	79.2%	100.0%
3929265	2484.5.1.2 ↗	mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH	0.68	61.0	6.03e-01	95.4%	93.3%
5023939	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.65	46.0	4.96e-01	90.8%	85.5%
3646441	2484.1.1.205 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27035	0.63	47.0	5.04e-01	92.3%	90.9%
4411984	2484.1.1.114 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C	0.60	51.0	4.59e-01	91.5%	93.9%
4983641	2484.1.1.49 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N	0.60	49.0	4.73e-01	87.7%	95.3%
3215204	207.1.1.0 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats	0.58	38.0	3.16e-01	80.8%	36.6%
4329438	7529.1.1.3 ↗	a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Peptidase_M17_N	0.57	45.0	4.14e-01	83.8%	86.5%
4376375	2484.1.1.49 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N	0.57	49.0	4.79e-01	93.8%	95.2%
3782631	2484.8.1.1 ↗	mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50	0.56	47.0	3.59e-01	90.0%	89.7%
3278599	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.56	45.0	4.78e-01	89.2%	100.0%
4933539	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.54	48.0	4.04e-01	96.9%	98.6%
5011615	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.53	45.0	3.94e-01	95.4%	91.9%
4091986	2484.1.1.37 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase	0.53	43.0	4.59e-01	87.7%	99.1%
4308615	2484.1.1.40 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX	0.52	45.0	4.52e-01	94.6%	93.3%
2623870	2484.1.1.44 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pox_A22	0.51	45.0	4.31e-01	96.2%	90.6%
5011606	2484.1.1.124 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605	0.51	44.0	3.96e-01	95.4%	92.3%
4355370	2484.1.1.40 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX	0.50	44.0	4.30e-01	95.4%	85.5%

D2 high residues 632-785

PDB

Domain cluster: rep: AB916497.1__BAS32805.1__X__00007__D17-171

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00665.33 best	rve	77.6	1.10e-21	59.1%	94.1%

D3 high residues 794-839

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00552.28 best	IN_DBD_C	31.1	1.60e-07	95.7%	66.7%

CATH (89)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4fw1A02	2.30.30.10	Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral	0.96	90.0	8.49e-01	100.0%	85.2%
5i4eA01	2.30.30.360	Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal	0.85	72.0	7.26e-01	93.5%	91.3%
1ex4B02	2.30.30.10	Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral	0.82	72.0	6.61e-01	100.0%	76.3%
4m4zA01	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.81	69.0	6.87e-01	95.7%	100.0%
2ldmA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.80	69.0	6.66e-01	100.0%	84.9%
2v1qA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.80	70.0	6.43e-01	100.0%	95.0%
2yrvA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.80	70.0	5.21e-01	100.0%	48.7%
1b7tA02	2.30.30.360	Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal	0.79	69.0	6.64e-01	100.0%	86.5%
2eqkA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.79	69.0	5.97e-01	100.0%	64.4%
2d9tA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.79	69.0	6.80e-01	100.0%	98.0%
4ytlA01	2.30.30.30	Mainly Beta › Roll › SH3 type barrels. ›	0.79	67.0	6.55e-01	100.0%	90.0%
2e6nA00	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.78	67.0	5.22e-01	100.0%	44.2%
3c4sA00	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.78	68.0	6.41e-01	100.0%	86.0%
2ckkA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.78	68.0	6.51e-01	100.0%	94.3%
1yn8A00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.77	66.0	6.17e-01	100.0%	94.9%
3goxA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.76	65.0	6.36e-01	100.0%	94.1%
1bkbA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.76	58.0	5.18e-01	82.6%	96.9%
1khcA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.76	68.0	6.03e-01	100.0%	81.5%
1igqB00	2.30.30.150	Mainly Beta › Roll › SH3 type barrels. › KorB, C-terminal domain	0.76	65.0	6.06e-01	100.0%	77.2%
2cudA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.76	64.0	5.49e-01	100.0%	69.6%
1mhnA00	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.75	67.0	6.17e-01	100.0%	81.4%
1lckA01	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.75	64.0	5.96e-01	100.0%	93.2%
2do3A01	2.30.30.30	Mainly Beta › Roll › SH3 type barrels. ›	0.75	63.0	6.14e-01	100.0%	88.2%
1zuyA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.75	63.0	5.94e-01	100.0%	98.3%
4pmwA04	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.75	53.0	4.19e-01	73.9%	79.1%
1x6gA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.75	63.0	5.33e-01	100.0%	70.4%
7u32F02	2.30.30.10	Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral	0.75	63.0	6.14e-01	100.0%	98.0%
4b9wA02	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.75	65.0	6.11e-01	100.0%	83.9%
7cfdA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.74	64.0	5.52e-01	100.0%	61.6%
2fpeA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.74	63.0	5.79e-01	100.0%	90.3%
1uebA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.74	56.0	5.07e-01	82.6%	96.8%
2eczA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.74	62.0	5.54e-01	100.0%	80.0%
6bhdA03	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.74	65.0	5.84e-01	100.0%	74.6%
1n27A00	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.73	63.0	5.01e-01	100.0%	54.2%
6vlfA03	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.73	61.0	5.79e-01	100.0%	96.6%
1x6bA01	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.73	61.0	5.58e-01	100.0%	85.9%
2vnuD04	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.72	52.0	4.36e-01	76.1%	100.0%
1k1zA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.72	59.0	5.14e-01	100.0%	80.8%
5f3yA05	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.71	60.0	5.17e-01	100.0%	79.2%
3ntkA02	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.71	61.0	5.10e-01	100.0%	56.2%
2kxcA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.71	59.0	5.35e-01	100.0%	86.6%
1zuuA00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.71	59.0	5.64e-01	97.8%	100.0%
3i35A00	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.70	57.0	5.48e-01	100.0%	98.2%
2diqA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.69	59.0	4.66e-01	100.0%	47.0%
3p8aA02	2.60.40.4320	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.69	48.0	3.86e-01	84.8%	37.8%
1ybyA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.68	49.0	4.47e-01	78.3%	95.3%
4chjA00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.68	53.0	3.94e-01	89.1%	73.4%
4xtvB02	2.30.30.100	Mainly Beta › Roll › SH3 type barrels. ›	0.67	56.0	5.56e-01	100.0%	91.7%
6l6jA02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.67	59.0	4.24e-01	100.0%	93.4%
1fl2A02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.67	60.0	4.39e-01	100.0%	96.8%
2xvlA01	2.60.40.1760	Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31)	0.67	44.0	2.86e-01	93.5%	13.7%
1ib8A02	2.30.30.180	Mainly Beta › Roll › SH3 type barrels. › Ribosome maturation factor RimP, C-terminal domain	0.66	55.0	5.02e-01	100.0%	80.6%
3cgbA01	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.66	57.0	3.89e-01	97.8%	48.2%
3dghA02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.66	58.0	4.29e-01	100.0%	97.6%
6bogA01	2.30.30.140	Mainly Beta › Roll › SH3 type barrels. ›	0.66	56.0	5.48e-01	100.0%	88.5%
6serA01	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.65	48.0	3.11e-01	80.4%	66.7%
3hrpA02	2.120.10.30	Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain	0.64	50.0	3.12e-01	91.3%	27.0%
3k30A03	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.64	56.0	4.04e-01	100.0%	96.2%
3gvpA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.63	45.0	3.19e-01	80.4%	39.0%
3dsmA00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.62	52.0	3.16e-01	97.8%	95.4%
7c2fB01	3.40.20.10	Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin	0.62	40.0	3.35e-01	100.0%	34.9%
5cemA01	3.30.200.20	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1	0.62	52.0	4.49e-01	95.7%	94.5%
5xu6C01	3.30.200.110	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Inositol-pentakisphosphate 2-kinase, N-lobe	0.62	47.0	3.70e-01	87.0%	76.9%
1x3zA04	2.20.25.10	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.62	48.0	4.62e-01	87.0%	98.1%
2ymsC00	2.40.10.480	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.61	49.0	4.29e-01	93.5%	88.0%
1xipA00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.61	49.0	2.93e-01	93.5%	17.4%
5g56A03	2.80.10.50	Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) ›	0.60	49.0	3.76e-01	100.0%	100.0%
5wbyC01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.60	49.0	3.01e-01	93.5%	22.7%
4ci8A01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.60	50.0	3.02e-01	95.7%	15.3%
1pbyB00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.60	52.0	3.12e-01	100.0%	96.7%
5xilA02	3.40.50.800	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain	0.60	51.0	3.69e-01	95.7%	77.3%
4o2zA01	3.30.200.20	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1	0.59	50.0	3.47e-01	95.7%	70.6%
2ymsB00	2.40.10.480	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.59	47.0	4.15e-01	93.5%	89.2%
1nj1A02	3.40.50.800	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain	0.59	52.0	3.97e-01	100.0%	90.4%
4hkhA00	2.30.110.20	Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like	0.58	47.0	3.45e-01	97.8%	89.3%
1f1sA03	2.60.220.10	Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal	0.58	47.0	3.96e-01	93.5%	61.0%
2ymsA00	2.40.128.630	Mainly Beta › Beta Barrel › Lipocalin ›	0.57	46.0	3.49e-01	95.7%	57.3%
6l4qB01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.57	42.0	3.15e-01	84.8%	39.3%
8ouzD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.57	46.0	3.02e-01	93.5%	89.5%
6g1nD01	3.30.160.250	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain ›	0.56	38.0	3.28e-01	71.7%	90.4%
1lc5A01	3.90.1150.10	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1	0.56	46.0	3.44e-01	95.7%	53.6%
1x0tA02	6.20.50.20	Special › Other non-globular › N-terminal domain of TfIIb ›	0.56	42.0	4.32e-01	82.6%	100.0%
3nqkA02	2.40.128.440	Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein PF14274, DUF4361	0.55	42.0	2.96e-01	87.0%	28.1%
2o7iA01	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.53	41.0	2.86e-01	89.1%	76.0%
4m0hA01	2.60.120.1440	Mainly Beta › Sandwich › Jelly Rolls ›	0.53	45.0	3.26e-01	100.0%	39.6%
6u5vB07	3.30.1120.100	Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain ›	0.53	42.0	3.24e-01	97.8%	73.6%
5ic7A00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.53	45.0	2.72e-01	100.0%	14.7%
4bs9A02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	42.0	2.75e-01	91.3%	54.1%
5xrkA00	2.60.120.200	Mainly Beta › Sandwich › Jelly Rolls ›	0.51	42.0	3.10e-01	100.0%	86.5%

ECOD (98)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1114686	4.1.1.8 ↗	beta barrels › SH3 › SH3 › SH3 › IN_DBD_C	0.95	89.0	8.25e-01	100.0%	82.1%
3938908	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.87	78.0	6.76e-01	100.0%	72.9%
3612184	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.85	75.0	6.82e-01	100.0%	75.0%
3541241	4.1.1.8 ↗	beta barrels › SH3 › SH3 › SH3 › IN_DBD_C	0.85	75.0	6.90e-01	100.0%	76.7%
2893010	4.1.1.8 ↗	beta barrels › SH3 › SH3 › SH3 › IN_DBD_C	0.84	75.0	7.10e-01	100.0%	87.0%
3475965	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.84	73.0	7.40e-01	97.8%	97.8%
3237262	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.84	73.0	5.49e-01	100.0%	40.9%
3333322	4.1.1.42 ↗	beta barrels › SH3 › SH3 › SH3 › Agenet	0.84	74.0	5.24e-01	100.0%	40.0%
4147056	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.83	72.0	5.57e-01	100.0%	45.0%
3669494	4.1.1.42 ↗	beta barrels › SH3 › SH3 › SH3 › Agenet	0.83	75.0	5.13e-01	100.0%	30.7%
3452043	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.83	72.0	5.08e-01	100.0%	33.3%
3828348	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.83	71.0	6.37e-01	100.0%	69.2%
3620094	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.82	72.0	6.83e-01	100.0%	81.8%
3359784	4.1.1.42 ↗	beta barrels › SH3 › SH3 › SH3 › Agenet	0.82	71.0	6.34e-01	100.0%	69.2%
3669492	4.1.1.42 ↗	beta barrels › SH3 › SH3 › SH3 › Agenet	0.82	71.0	5.06e-01	100.0%	40.0%
1140051	4.1.1.1 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_1	0.82	71.0	6.96e-01	97.8%	98.0%
3619813	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.81	72.0	5.35e-01	100.0%	40.0%
3267329	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.81	71.0	5.20e-01	100.0%	38.4%
3928987	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.81	71.0	5.92e-01	100.0%	70.0%
None	—		0.81	71.0	3.85e-01	100.0%	5.7%
3465976	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.81	69.0	6.21e-01	100.0%	69.2%
3315100	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.81	69.0	6.19e-01	100.0%	69.2%
3313119	4.1.1.42 ↗	beta barrels › SH3 › SH3 › SH3 › Agenet	0.81	69.0	5.80e-01	100.0%	56.2%
3480822	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.80	71.0	6.98e-01	100.0%	94.0%
3840679	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.80	71.0	5.57e-01	100.0%	48.4%
None	—		0.80	70.0	3.78e-01	100.0%	5.2%
3218198	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.80	69.0	6.56e-01	100.0%	81.8%
3547084	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.80	70.0	5.63e-01	100.0%	51.1%
4075769	4.1.1.154 ↗	beta barrels › SH3 › SH3 › SH3 › DUF4772	0.80	70.0	6.66e-01	100.0%	83.6%
3842631	4.1.1.243 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_Myosin-XVIIIa	0.80	71.0	6.16e-01	100.0%	72.9%
4002896	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.79	69.0	5.55e-01	100.0%	51.1%
3398093	4.1.1.43 ↗	beta barrels › SH3 › SH3 › SH3 › SMN_Tudor	0.79	68.0	6.30e-01	100.0%	76.7%
3406803	4.1.1.54 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_2	0.79	67.0	5.88e-01	97.8%	77.1%
4026957	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.79	68.0	6.31e-01	100.0%	76.7%
3241793	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.22e-01	100.0%	43.8%
3883165	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.32e-01	100.0%	47.0%
3663761	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	67.0	5.15e-01	100.0%	42.9%
3883159	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.49e-01	100.0%	51.1%
3920666	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	69.0	5.52e-01	100.0%	51.1%
3501699	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	68.0	5.71e-01	100.0%	58.7%
3535278	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	69.0	6.33e-01	100.0%	76.7%
3389169	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	67.0	5.51e-01	100.0%	52.9%
3389177	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.31e-01	100.0%	46.0%
3938389	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.60e-01	100.0%	56.5%
3517728	4.1.1.43 ↗	beta barrels › SH3 › SH3 › SH3 › SMN_Tudor	0.78	69.0	6.01e-01	100.0%	65.7%
3571064	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.57e-01	100.0%	55.3%
3931993	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	69.0	6.35e-01	100.0%	76.7%
3913334	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	69.0	6.01e-01	100.0%	65.7%
3558926	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	69.0	5.49e-01	100.0%	51.1%
3881121	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.78	68.0	5.29e-01	100.0%	47.0%
3231263	4.1.1.43 ↗	beta barrels › SH3 › SH3 › SH3 › SMN_Tudor	0.78	69.0	6.76e-01	100.0%	92.0%
3936926	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	68.0	6.11e-01	100.0%	70.8%
4890270	4.1.1.33 ↗	beta barrels › SH3 › SH3 › SH3 › Myosin_N	0.78	67.0	6.40e-01	100.0%	83.3%
3576438	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.78	69.0	5.49e-01	100.0%	52.2%
3429682	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.77	65.0	5.64e-01	100.0%	60.0%
3581143	4.1.1.43 ↗	beta barrels › SH3 › SH3 › SH3 › SMN_Tudor	0.77	69.0	6.12e-01	100.0%	70.8%
3576128	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.77	69.0	5.10e-01	100.0%	44.3%
4317035	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	68.0	5.55e-01	100.0%	54.1%
3274551	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	67.0	5.72e-01	100.0%	62.7%
3877478	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	68.0	5.24e-01	100.0%	46.0%
3395948	4.1.1.43 ↗	beta barrels › SH3 › SH3 › SH3 › SMN_Tudor	0.77	68.0	6.45e-01	100.0%	85.5%
3561707	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	64.0	5.08e-01	100.0%	45.0%
3881111	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	67.0	5.37e-01	100.0%	51.1%
4055256	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.77	67.0	5.37e-01	100.0%	51.1%
3881119	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.76	66.0	5.55e-01	100.0%	57.5%
3535268	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.76	66.0	5.26e-01	100.0%	49.5%
3830187	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.76	66.0	6.30e-01	100.0%	83.6%
3765126	4.1.1.1 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_1	0.76	65.0	6.18e-01	100.0%	100.0%
3815479	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.76	64.0	5.53e-01	100.0%	60.0%
3879068	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.76	66.0	5.43e-01	100.0%	55.3%
3999723	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.76	66.0	4.63e-01	100.0%	30.7%
3765289	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.76	66.0	5.32e-01	100.0%	51.1%
4950396	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.76	59.0	5.63e-01	100.0%	74.5%
3765274	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.75	66.0	5.29e-01	100.0%	54.4%
3547102	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.75	65.0	5.38e-01	100.0%	55.3%
3547106	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.75	66.0	5.28e-01	100.0%	54.4%
3547093	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.75	65.0	5.24e-01	100.0%	52.2%
3744277	4.1.1.33 ↗	beta barrels › SH3 › SH3 › SH3 › Myosin_N	0.74	64.0	6.31e-01	100.0%	92.0%
3547089	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.74	63.0	5.17e-01	100.0%	52.2%
3256498	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.74	65.0	6.18e-01	100.0%	83.6%
3407854	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.74	64.0	5.10e-01	100.0%	48.4%
3881123	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.74	64.0	5.27e-01	100.0%	54.1%
3881117	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.73	65.0	5.04e-01	100.0%	49.0%
3620905	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.73	63.0	5.12e-01	100.0%	51.1%
4589595	4.1.1.447 ↗	beta barrels › SH3 › SH3 › SH3 › PF28065	0.73	62.0	5.59e-01	100.0%	75.4%
3469800	4.1.1.1 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_1	0.72	59.0	5.07e-01	97.8%	67.5%
3482646	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.72	60.0	4.00e-01	100.0%	27.5%
4011604	4.1.1.13 ↗	beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd	0.72	63.0	5.37e-01	100.0%	68.0%
3226229	4.1.1.1 ↗	beta barrels › SH3 › SH3 › SH3 › SH3_1	0.71	59.0	5.38e-01	100.0%	86.2%
3261235	4.1.1.9 ↗	beta barrels › SH3 › SH3 › SH3 › TUDOR	0.71	62.0	5.11e-01	100.0%	58.8%
3243842	375.1.1.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related	0.68	51.0	3.96e-01	84.8%	53.6%
4169111	2003.1.2.12 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › DAO	0.67	57.0	3.71e-01	97.8%	59.1%
None	—		0.67	57.0	3.36e-01	97.8%	50.7%
5072324	101.1.2.70 ↗	alpha arrays › HTH › HTH › winged helix domain › PqqD	0.66	49.0	3.95e-01	82.6%	50.5%
4932368	2005.1.1.17 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1f	0.66	59.0	3.62e-01	100.0%	19.2%
4010184	2003.1.2.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox	0.64	55.0	4.08e-01	100.0%	95.2%
3982652	2003.1.2.24 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2	0.64	55.0	3.92e-01	100.0%	82.1%
3948516	2.1.1.10 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP	0.60	46.0	4.17e-01	82.6%	98.5%

D4 medium residues 1-85_117-149

PDB

Domain cluster: rep: pol_protein,_partial__YP_002308474__Simian_T-cell_lymphotropic_virus_6__481147__D16-81_108-143

D5 medium residues 86-116_150-225

PDB

Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00078.33 best	RVT_1	55.0	1.40e-14	71.0%	34.5%

CATH (79)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4hkqA01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.90	86.0	7.60e-01	100.0%	75.0%
7uinD01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.86	81.0	6.82e-01	100.0%	85.0%
1bqnA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.86	72.0	7.68e-01	97.2%	100.0%
4ol8A01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.84	73.0	6.74e-01	100.0%	73.3%
1in0A01	3.30.70.860	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.79	51.0	6.12e-01	81.3%	100.0%
1gx5A03	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.77	70.0	6.71e-01	99.1%	97.5%
4ctaA02	3.30.70.2860	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.76	51.0	6.06e-01	86.0%	98.7%
6d9mA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.76	67.0	5.91e-01	95.3%	90.1%
7e6gA01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.75	66.0	5.86e-01	95.3%	91.3%
1hi9A02	3.30.1360.130	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Dipeptide transport protein	0.73	42.0	4.94e-01	74.8%	80.3%
2diuA01	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.73	49.0	5.71e-01	81.3%	100.0%
4wxaA00	3.30.310.50	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain	0.73	51.0	5.66e-01	74.8%	90.5%
6zxbA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.72	63.0	5.71e-01	95.3%	94.4%
4aimA03	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.72	45.0	5.42e-01	74.8%	95.8%
4lowA00	3.30.1360.20	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase	0.72	47.0	5.26e-01	71.0%	84.5%
3jcmH04	3.30.70.870	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3	0.72	49.0	5.65e-01	86.0%	98.7%
1yz7A02	3.30.70.1130	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha	0.72	56.0	6.01e-01	81.3%	100.0%
3hvwA00	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.72	64.0	5.61e-01	98.1%	84.9%
1usmA00	3.30.1360.20	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase	0.72	47.0	5.38e-01	70.1%	92.2%
4kyzA00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.71	52.0	4.45e-01	84.1%	48.5%
5oyhD00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.71	62.0	5.11e-01	93.5%	73.5%
2mq8A00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.71	57.0	5.60e-01	84.1%	89.3%
4zmuA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.71	64.0	5.62e-01	99.1%	89.0%
2cveA02	3.30.70.240	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.71	44.0	5.31e-01	80.4%	100.0%
2w01B00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.71	59.0	4.84e-01	90.7%	69.5%
3pjxA01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.71	63.0	5.34e-01	100.0%	80.1%
1x9mA03	3.30.70.370	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.71	64.0	5.40e-01	100.0%	94.9%
1azsA00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.71	60.0	4.93e-01	91.6%	70.5%
3mtkA00	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.71	64.0	5.55e-01	100.0%	82.2%
2ckwA03	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.71	62.0	6.07e-01	96.3%	100.0%
6lpnA03	3.30.70.2190	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.70	57.0	5.58e-01	85.0%	93.0%
4wp3C00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.70	61.0	5.06e-01	95.3%	68.4%
5jxsA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.70	63.0	5.71e-01	99.1%	85.2%
2ebbA00	3.30.1360.20	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase	0.70	48.0	5.02e-01	72.0%	78.1%
1tuaA02	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.70	49.0	4.96e-01	72.0%	73.3%
4oloB00	3.30.70.1710	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain	0.69	41.0	4.60e-01	77.6%	75.0%
2kl8A00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.69	49.0	5.41e-01	82.2%	92.9%
5yuyA01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.69	56.0	5.43e-01	87.9%	81.1%
3aqoA01	3.30.70.3400	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.69	50.0	5.63e-01	82.2%	100.0%
5axmB00	3.30.70.3000	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1)	0.69	56.0	4.30e-01	86.9%	49.0%
2qv6B02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.69	56.0	5.40e-01	87.9%	85.2%
1s5jA03	3.90.1600.10	Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain	0.69	62.0	5.44e-01	99.1%	97.5%
1ybtB00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.69	58.0	4.96e-01	91.6%	67.4%
3ofgB00	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.69	51.0	5.60e-01	84.1%	96.6%
3devA02	3.10.310.30	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 ›	0.69	38.0	3.72e-01	74.8%	49.1%
1fx2A00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.68	57.0	4.43e-01	90.7%	97.9%
2cxiA02	3.50.40.10	Alpha Beta › 3-Layer(bba) Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 3 › Phenylalanyl-trna Synthetase, Chain B, domain 3	0.68	56.0	4.55e-01	87.9%	88.9%
3dfeA00	3.30.70.120	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.68	48.0	5.29e-01	86.0%	93.9%
1vbkA01	3.30.70.1510	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like	0.68	50.0	5.52e-01	85.0%	98.8%
3ungC03	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.68	56.0	5.15e-01	86.9%	74.4%
4qmfD02	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.68	46.0	4.97e-01	71.0%	81.5%
2ifxA01	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.68	52.0	5.70e-01	83.2%	100.0%
4er8A00	3.30.70.1290	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like	0.68	55.0	4.74e-01	86.9%	90.9%
2c5sA01	3.30.2130.30	Alpha Beta › 2-Layer Sandwich › VC0802-like ›	0.68	54.0	4.61e-01	85.0%	92.3%
1vdhA01	3.30.70.1030	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1	0.67	54.0	5.21e-01	85.0%	82.6%
3r5gA00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.67	56.0	4.63e-01	91.6%	71.8%
1lxnA00	3.30.70.930	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.67	48.0	5.01e-01	82.2%	81.6%
1vk8A00	3.30.70.930	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.67	47.0	5.03e-01	84.1%	84.9%
1weyA00	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.67	49.0	5.01e-01	86.0%	79.8%
1dcoA00	3.30.1360.20	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase	0.67	46.0	4.74e-01	74.8%	75.8%
1lxjA00	3.30.70.930	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.67	47.0	4.84e-01	83.2%	76.7%
3gqcC01	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.67	54.0	4.96e-01	86.9%	72.3%
1t0tV02	3.30.70.1030	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1	0.66	53.0	5.31e-01	85.0%	89.2%
2a6mA00	3.30.70.1290	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like	0.66	53.0	5.00e-01	86.9%	87.7%
1r89A03	3.30.70.590	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain	0.66	55.0	5.16e-01	92.5%	85.8%
1vx7X00	3.30.1360.210	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 ›	0.65	49.0	5.16e-01	80.4%	92.8%
5k9fA00	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.64	50.0	5.12e-01	83.2%	94.2%
3u5eU00	3.30.1360.210	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 ›	0.63	51.0	5.27e-01	86.0%	93.0%
3luyA03	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.63	47.0	5.08e-01	82.2%	93.3%
2a2cA02	3.30.70.3170	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.63	46.0	5.09e-01	89.7%	100.0%
3dcaA00	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.61	48.0	4.50e-01	84.1%	82.3%
2i8eA01	3.30.70.240	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.60	41.0	4.69e-01	84.1%	100.0%
3e3xA01	3.30.70.870	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3	0.60	48.0	4.78e-01	87.9%	85.8%
4erdA00	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.59	44.0	4.47e-01	86.0%	79.6%
3znuA00	3.30.70.1060	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel	0.58	44.0	4.67e-01	82.2%	91.5%
2l9dA00	3.30.70.2340	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF12112 family, DUF3579	0.56	42.0	4.25e-01	85.0%	80.6%
5t5sA01	3.10.310.40	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 ›	0.53	39.0	3.73e-01	77.6%	74.4%
1s12A00	3.30.70.1490	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp	0.51	38.0	3.95e-01	78.5%	90.4%
3g98A00	3.10.310.40	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 ›	0.51	37.0	3.70e-01	76.6%	82.0%

ECOD (100)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3571315	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.98	95.0	7.02e-01	100.0%	59.6%
1893002	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.92	88.0	6.40e-01	100.0%	55.9%
3983816	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.91	86.0	6.31e-01	100.0%	74.4%
3945039	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.90	85.0	5.78e-01	100.0%	55.8%
3479534	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.90	85.0	5.47e-01	100.0%	50.7%
4826122	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.90	73.0	6.80e-01	85.0%	100.0%
3937440	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	84.0	6.11e-01	100.0%	52.1%
4434853	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	84.0	6.29e-01	100.0%	66.7%
1186663	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	85.0	6.28e-01	100.0%	58.5%
4152428	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	85.0	5.66e-01	100.0%	54.1%
3260113	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	80.0	7.99e-01	94.4%	97.3%
4365193	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	84.0	5.82e-01	100.0%	77.1%
3939861	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	83.0	7.92e-01	98.1%	92.5%
3251732	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.89	84.0	6.05e-01	100.0%	50.0%
3939572	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.88	83.0	6.34e-01	100.0%	94.2%
3923429	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.88	84.0	6.65e-01	100.0%	69.2%
3265942	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.88	83.0	6.87e-01	100.0%	77.1%
4608078	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.88	82.0	5.56e-01	100.0%	74.6%
3934202	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.88	80.0	7.08e-01	96.3%	91.7%
3927049	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.87	81.0	5.32e-01	100.0%	48.3%
3968281	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.86	81.0	6.11e-01	100.0%	72.3%
3708806	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.86	81.0	6.14e-01	99.1%	74.2%
3935908	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.86	65.0	6.11e-01	77.6%	88.8%
3781210	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.86	81.0	5.95e-01	100.0%	51.0%
3939319	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.86	80.0	5.28e-01	100.0%	47.8%
3643305	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.86	77.0	7.02e-01	94.4%	91.9%
3737895	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.85	81.0	5.93e-01	100.0%	52.8%
3935796	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.85	81.0	6.74e-01	100.0%	76.5%
5018583	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.85	77.0	5.38e-01	97.2%	53.0%
3193439	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.85	79.0	5.59e-01	100.0%	70.7%
3960648	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.85	79.0	5.56e-01	100.0%	64.6%
3932482	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.85	80.0	5.95e-01	100.0%	54.3%
3934891	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	80.0	5.96e-01	100.0%	55.0%
3510717	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	80.0	5.81e-01	100.0%	50.4%
3927365	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	79.0	5.89e-01	100.0%	53.1%
4497954	304.48.1.73 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N	0.84	77.0	5.38e-01	98.1%	54.5%
3927736	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	77.0	5.75e-01	97.2%	52.9%
4096485	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	79.0	5.75e-01	100.0%	50.8%
3427907	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	79.0	5.75e-01	100.0%	50.8%
3930235	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	79.0	5.73e-01	100.0%	49.4%
3925602	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.84	79.0	5.76e-01	100.0%	50.4%
3669721	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.84	76.0	5.33e-01	96.3%	83.0%
3927691	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	79.0	5.81e-01	100.0%	52.8%
3257066	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	78.0	5.87e-01	100.0%	55.0%
4618808	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	78.0	5.67e-01	100.0%	48.5%
3236725	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	77.0	5.70e-01	100.0%	71.9%
3785231	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	78.0	5.48e-01	100.0%	43.0%
3940445	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.83	78.0	5.73e-01	100.0%	50.6%
4068028	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.82	77.0	5.49e-01	100.0%	55.9%
3252343	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.82	77.0	5.65e-01	100.0%	50.8%
3678489	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.82	77.0	6.14e-01	100.0%	71.5%
3926633	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.82	77.0	6.27e-01	100.0%	69.7%
3216767	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.82	77.0	5.48e-01	100.0%	44.9%
3241316	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.80	74.0	5.06e-01	98.1%	52.2%
3507895	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.78	71.0	5.54e-01	96.3%	55.7%
3315278	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.78	65.0	6.14e-01	87.9%	76.8%
4869676	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.77	70.0	5.49e-01	97.2%	61.7%
1411401	304.48.1.7 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1	0.76	69.0	4.40e-01	98.1%	47.2%
4600602	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.75	54.0	6.06e-01	83.2%	100.0%
3529282	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.74	70.0	5.38e-01	100.0%	66.4%
4246496	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.74	69.0	5.31e-01	100.0%	64.9%
3973496	304.48.1.14 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF	0.74	67.0	5.81e-01	100.0%	84.2%
4588604	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.74	66.0	4.86e-01	97.2%	58.9%
4038014	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.73	53.0	5.66e-01	80.4%	88.9%
4605419	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.73	52.0	5.90e-01	83.2%	100.0%
3934934	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.73	62.0	4.67e-01	90.7%	54.7%
3469955	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.72	61.0	4.53e-01	90.7%	55.8%
3958184	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.72	59.0	5.18e-01	87.9%	70.3%
4215083	304.48.1.10 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS	0.71	62.0	5.80e-01	94.4%	80.0%
4649093	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.71	61.0	4.98e-01	91.6%	59.5%
4952701	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.71	59.0	4.08e-01	88.8%	28.2%
5024216	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.70	57.0	4.80e-01	86.0%	52.6%
4096785	304.48.1.10 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS	0.70	57.0	5.45e-01	86.9%	77.6%
4481814	304.41.1.1 ↗	a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N	0.70	57.0	4.99e-01	86.0%	62.6%
4514423	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.70	48.0	5.50e-01	80.4%	100.0%
1681577	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.70	61.0	5.19e-01	95.3%	69.8%
3956622	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.69	59.0	5.66e-01	93.5%	94.4%
278624	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.69	58.0	4.96e-01	91.6%	67.4%
4090279	304.36.1.1 ↗	a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › DUF520	0.68	52.0	5.75e-01	81.3%	100.0%
4586449	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.68	60.0	4.90e-01	95.3%	73.3%
3511287	304.48.1.4 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc	0.68	59.0	4.59e-01	94.4%	63.0%
3593926	304.6.1.0 ↗	a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain	0.68	58.0	4.23e-01	92.5%	76.2%
5039662	304.48.1.112 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › SatD	0.68	56.0	5.26e-01	88.8%	85.4%
4946581	304.48.1.111 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS_HHH	0.67	55.0	5.16e-01	87.9%	75.4%
3987638	304.48.1.49 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_GdpP	0.67	54.0	4.83e-01	86.9%	74.7%
3593319	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.67	55.0	4.59e-01	89.7%	65.4%
3717430	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.66	60.0	4.40e-01	100.0%	87.0%
4056579	304.28.1.4 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st	0.66	52.0	5.54e-01	84.1%	100.0%
4947478	304.26.1.0 ↗	a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like	0.66	48.0	5.09e-01	83.2%	86.3%
3415133	304.151.1.0 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase	0.66	51.0	5.39e-01	83.2%	100.0%
4234725	304.28.1.4 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st	0.66	54.0	5.65e-01	86.9%	97.9%
4145731	304.48.1.22 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III	0.66	53.0	5.28e-01	86.9%	85.5%
5002487	304.55.2.1 ↗	a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp	0.65	53.0	4.92e-01	88.8%	85.9%
3985106	304.55.2.1 ↗	a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp	0.64	52.0	5.16e-01	87.9%	100.0%
3392977	304.55.2.9 ↗	a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › DUF4780	0.63	50.0	5.35e-01	86.0%	100.0%
3738917	304.57.1.2 ↗	a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › Pop8	0.63	51.0	5.20e-01	87.9%	95.1%
4934750	304.57.1.1 ↗	a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14	0.62	54.0	5.41e-01	93.5%	93.6%
4968297	304.4.1.2 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase	0.62	46.0	5.08e-01	84.1%	98.8%
5057057	304.128.1.0 ↗	a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB	0.58	44.0	4.70e-01	79.4%	100.0%
3281659	304.4.1.0 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel	0.58	44.0	4.56e-01	85.0%	87.0%

D6 medium residues 387-438

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4ymhD00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	40.0	2.78e-01	98.1%	68.8%
5z50A01	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.51	39.0	3.18e-01	98.1%	98.5%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2084852	7523.1.1.15 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate	0.50	37.0	3.49e-01	86.5%	93.2%
3974169	7523.1.1.0 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II	0.50	37.0	3.29e-01	92.3%	94.7%

D7 medium residues 574-608

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02022.26 best	Integrase_Zn	47.2	2.50e-12	91.4%	84.2%

CATH (61)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1k6yA01	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.97	87.0	7.92e-01	100.0%	76.1%
5cz2G00	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.95	86.0	8.13e-01	100.0%	85.4%
7u32G01	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.87	73.0	6.37e-01	100.0%	62.5%
3f8mA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.83	70.0	5.81e-01	100.0%	67.7%
2ia0A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.76	63.0	5.59e-01	100.0%	72.2%
1r1uB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.76	62.0	4.69e-01	100.0%	40.9%
1sfxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.76	62.0	4.54e-01	100.0%	37.5%
2e18A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.75	57.0	3.53e-01	100.0%	14.5%
3r0aA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	61.0	4.32e-01	100.0%	32.5%
4o5vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	62.0	5.05e-01	100.0%	59.2%
1e3oC02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	59.0	5.57e-01	100.0%	91.7%
2cobA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	57.0	5.51e-01	100.0%	77.3%
1j5yA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	59.0	5.06e-01	100.0%	64.1%
4pcqA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	59.0	5.45e-01	100.0%	78.0%
2vxzA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	61.0	5.11e-01	100.0%	60.6%
1tc3C00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	57.0	5.33e-01	100.0%	76.5%
5jk0B01	1.10.443.10	Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core	0.73	62.0	3.97e-01	100.0%	64.2%
2k9lA00	1.10.10.1330	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA polymerase sigma-54 factor, core-binding domain	0.73	59.0	4.76e-01	100.0%	56.6%
1rykA00	1.10.1470.10	Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › YjbJ	0.73	56.0	4.48e-01	85.7%	63.8%
4jp0A03	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.73	57.0	5.81e-01	97.1%	94.1%
2dbbB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	58.0	5.21e-01	100.0%	70.9%
3cuqB03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	61.0	4.99e-01	100.0%	58.0%
4ijaA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	57.0	4.96e-01	100.0%	61.9%
2x48A00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.72	55.0	5.02e-01	100.0%	61.1%
4wcgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	57.0	4.99e-01	100.0%	63.9%
1s3jA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	58.0	4.94e-01	100.0%	60.9%
4ha8A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	58.0	4.96e-01	100.0%	65.1%
2r0qC02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.71	57.0	5.13e-01	100.0%	85.5%
5f7qC01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	58.0	4.79e-01	100.0%	55.7%
5xsoA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	57.0	4.60e-01	100.0%	44.7%
3dv8A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	56.0	4.59e-01	100.0%	59.0%
3tgnB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	56.0	4.87e-01	100.0%	60.3%
3vfzB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	56.0	4.84e-01	100.0%	58.7%
2p0wA03	1.10.10.390	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.70	54.0	4.99e-01	100.0%	87.0%
2xrnB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	54.0	4.71e-01	100.0%	62.5%
2lfwA01	1.20.140.160	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain	0.69	56.0	3.82e-01	100.0%	26.2%
1a04A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	55.0	4.43e-01	100.0%	46.3%
1gdtB03	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.69	54.0	5.21e-01	100.0%	82.2%
2hyjA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.69	54.0	5.11e-01	97.1%	89.1%
5eriA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	54.0	3.71e-01	100.0%	24.2%
2o8xA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	53.0	4.72e-01	100.0%	62.3%
2q0oA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	53.0	4.59e-01	100.0%	67.2%
2zkzC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	52.0	4.22e-01	100.0%	43.7%
3lsgA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.68	54.0	4.88e-01	100.0%	87.3%
1qb2A00	1.10.260.30	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › Signal recognition particle, SRP54 subunit, M-domain	0.67	54.0	4.04e-01	100.0%	48.1%
3hugA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	52.0	4.27e-01	100.0%	47.5%
6jqsA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	52.0	4.51e-01	97.1%	55.2%
1rr7A02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.67	54.0	5.02e-01	100.0%	77.1%
4u7bA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	52.0	5.16e-01	100.0%	100.0%
3p7nA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	52.0	4.35e-01	100.0%	62.5%
3ulqB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	52.0	4.65e-01	100.0%	75.9%
1l3lA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	50.0	4.44e-01	100.0%	58.7%
3onqA03	1.10.10.2840	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain	0.65	50.0	3.60e-01	100.0%	35.9%
2oi8A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.64	49.0	3.20e-01	100.0%	24.1%
5f64A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	49.0	4.09e-01	100.0%	49.3%
3op9A01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.61	47.0	3.89e-01	88.6%	52.9%
1umqA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.61	45.0	4.15e-01	100.0%	61.7%
2napA03	3.40.228.10	Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2	0.60	50.0	3.09e-01	100.0%	38.2%
3iuoA00	1.10.10.1390	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › ATP-dependent DNA helicase RecQ	0.60	45.0	3.49e-01	100.0%	86.2%
2k9qA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.56	42.0	4.12e-01	77.1%	77.5%
6xzqA01	3.40.91.90	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain	0.52	43.0	2.86e-01	100.0%	67.3%

ECOD (72)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1738816	101.1.1.14 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Integrase_Zn	0.97	89.0	8.18e-01	100.0%	79.5%
4874560	101.1.1.14 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Integrase_Zn	0.97	87.0	7.61e-01	100.0%	68.6%
1738401	101.1.1.14 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Integrase_Zn	0.96	86.0	8.14e-01	100.0%	85.4%
4919061	101.1.1.14 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Integrase_Zn	0.95	85.0	7.86e-01	100.0%	79.5%
3971636	101.28.1.0 ↗	alpha arrays › HTH › helical bundles in FlhC-like proteins › helical bundles in FlhC-like proteins	0.84	67.0	6.60e-01	100.0%	85.0%
4495608	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.83	68.0	6.25e-01	100.0%	72.0%
3259994	4964.1.1.1 ↗	alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A	0.81	66.0	4.51e-01	97.1%	29.2%
3908710	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.80	68.0	4.95e-01	100.0%	35.8%
3455559	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.79	66.0	4.88e-01	100.0%	35.8%
3985633	101.1.1.13 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1	0.77	61.0	5.46e-01	100.0%	61.8%
3926525	101.1.6.0 ↗	alpha arrays › HTH › HTH › TrpR	0.77	61.0	6.02e-01	100.0%	87.5%
3905610	2484.1.1.120 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_4	0.77	63.0	3.64e-01	100.0%	66.4%
3943148	101.1.1.63 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_28	0.76	62.0	5.72e-01	100.0%	70.0%
3954433	101.1.1.17 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_7	0.76	61.0	5.78e-01	100.0%	75.6%
3983783	101.1.1.13 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1	0.76	60.0	4.59e-01	100.0%	38.9%
3587739	101.1.2.66 ↗	alpha arrays › HTH › HTH › winged helix domain › Mga	0.75	61.0	5.03e-01	100.0%	54.3%
3448782	101.1.1.267 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PF26138	0.74	62.0	4.56e-01	100.0%	37.0%
3953011	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.74	57.0	5.19e-01	100.0%	61.8%
4979402	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.74	61.0	5.27e-01	100.0%	65.0%
4460997	101.1.1.63 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_28	0.74	58.0	5.55e-01	100.0%	75.6%
3616846	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	60.0	5.14e-01	97.1%	75.0%
3989117	101.1.1.129 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_4	0.73	59.0	4.37e-01	100.0%	34.0%
3278040	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	59.0	5.16e-01	100.0%	65.0%
5051680	101.1.11.0 ↗	alpha arrays › HTH › HTH › Ribbon-helix-helix	0.73	59.0	4.67e-01	97.1%	52.5%
4031116	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	59.0	5.13e-01	100.0%	60.0%
3879118	101.1.1.60 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_23	0.73	58.0	5.22e-01	100.0%	65.5%
3989075	101.1.3.11 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_Tnp_ISL3	0.72	56.0	5.62e-01	100.0%	89.5%
4948953	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.72	58.0	4.95e-01	100.0%	58.5%
3589359	101.1.1.68 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_38	0.72	57.0	5.62e-01	100.0%	97.5%
4604979	101.1.6.4 ↗	alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C	0.72	60.0	4.41e-01	100.0%	35.6%
3452698	101.1.10.37 ↗	alpha arrays › HTH › HTH › Cyclin-like › PF26138	0.72	59.0	4.46e-01	100.0%	38.9%
3969325	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.72	55.0	4.48e-01	88.6%	54.3%
3815501	101.1.10.37 ↗	alpha arrays › HTH › HTH › Cyclin-like › PF26138	0.72	59.0	4.46e-01	100.0%	38.9%
3670113	101.1.1.129 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_4	0.72	59.0	4.48e-01	100.0%	41.1%
3452676	101.1.1.267 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PF26138	0.71	59.0	4.41e-01	100.0%	38.9%
3877765	101.1.1.35 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_psq	0.71	54.0	5.38e-01	100.0%	85.0%
4197050	101.1.6.4 ↗	alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C	0.71	60.0	4.34e-01	100.0%	35.2%
3837445	101.1.1.267 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PF26138	0.71	59.0	4.59e-01	100.0%	43.5%
2332937	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.71	57.0	4.64e-01	100.0%	45.9%
3376425	101.1.1.267 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PF26138	0.71	58.0	4.52e-01	100.0%	43.5%
4165809	101.1.6.4 ↗	alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C	0.71	53.0	4.22e-01	91.4%	38.8%
2464007	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.71	55.0	4.75e-01	100.0%	53.0%
3967748	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.71	56.0	4.41e-01	100.0%	43.5%
3283500	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.70	56.0	5.20e-01	100.0%	74.0%
3886097	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.70	57.0	4.60e-01	100.0%	49.3%
4198219	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.70	53.0	5.11e-01	100.0%	73.3%
4395941	101.1.1.17 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_7	0.70	53.0	5.36e-01	100.0%	94.3%
149489	101.1.1.95 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PhyR_sigma-like	0.69	56.0	4.46e-01	100.0%	46.3%
3502245	101.1.6.13 ↗	alpha arrays › HTH › HTH › TrpR › HTH_28	0.69	53.0	5.07e-01	100.0%	75.6%
4999211	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	56.0	5.30e-01	100.0%	77.8%
3967026	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.69	54.0	4.46e-01	100.0%	49.3%
3793383	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.69	52.0	4.54e-01	100.0%	52.3%
3483301	4964.1.1.0 ↗	alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I	0.69	52.0	3.58e-01	100.0%	22.7%
4986612	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.69	54.0	5.15e-01	100.0%	82.2%
4470400	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	53.0	4.53e-01	100.0%	52.9%
4863786	101.1.1.60 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_23	0.68	55.0	4.93e-01	100.0%	67.3%
4934485	101.1.1.107 ↗	alpha arrays › HTH › HTH › Three-helical HTH › DUF134	0.68	53.0	4.43e-01	100.0%	51.4%
165630	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.68	53.0	4.61e-01	100.0%	68.2%
4963466	101.1.1.368 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_58	0.68	52.0	5.02e-01	100.0%	82.2%
3944309	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.67	52.0	4.85e-01	97.1%	72.0%
5057202	101.1.3.8 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › Sigma70_r4_2	0.67	52.0	4.42e-01	100.0%	51.4%
4627768	101.1.2.786 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_Tnp_1	0.67	53.0	5.21e-01	97.1%	100.0%
4479119	101.1.1.13 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1	0.67	52.0	4.75e-01	100.0%	72.7%
5043241	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.67	53.0	5.25e-01	100.0%	97.5%
5043001	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.67	51.0	3.88e-01	100.0%	35.2%
4590594	101.1.1.18 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_8	0.66	52.0	5.13e-01	97.1%	97.5%
3640035	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.66	53.0	4.18e-01	100.0%	43.5%
3284292	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.64	49.0	3.90e-01	100.0%	41.1%
3587017	101.1.1.63 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_28	0.63	48.0	4.61e-01	97.1%	86.7%
4142399	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.62	47.0	3.80e-01	100.0%	42.2%
3588243	101.1.4.3 ↗	alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3	0.62	49.0	4.27e-01	97.1%	70.0%
5019932	3151.1.1.0 ↗	alpha arrays › SPP1 phage GP23.1 › SPP1 phage GP23.1 › SPP1 phage GP23.1	0.58	43.0	4.31e-01	100.0%	100.0%