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polyA_polymerase_large_subunit
Euk-VirCotia_virus_SPAn232
polyA_polymerase_large_subunit__YP_005296237__Cotia_virus_SPAn232__930275
Identity
- Accession:
- YP_005296237 ↗
- Protein ID:
- polyA_polymerase_large_subunit
- Kingdom:
- euk
Quality
91.6
mean pLDDT
Cluster
View cluster (34 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-107
Domain cluster:
rep: poly-A-_polymerase_catalytic_subunit_VP55__YP_008003861__Adoxophyes_honmai_entomopoxvirus_L__1293540__D11-107
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12630.14 best | Pox_polyA_pol_N | 141.1 | 2.30e-41 | 100.0% | 95.4% |
D2
high
residues 122-266_453-469
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03296.21 best | Pox_polyA_pol | 215.9 | 2.90e-64 | 91.4% | 98.0% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3er9B03 | 3.30.460.60 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Poxvirus poly(A) polymerase, nucleotidyltransferase domain | 0.98 | 79.0 | 8.76e-01 | 82.1% | 99.2% |
| 3e0rB01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.66 | 31.0 | 3.54e-01 | 77.8% | 58.8% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 1.00 | 70.0 | 6.98e-01 | 71.6% | 69.9% | |
| 1179385 | 316.1.1.7 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Pox_polyA_pol | 0.99 | 81.0 | 7.88e-01 | 89.5% | 78.0% |
| 1544851 | 316.1.1.29 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Poly_A_pol_cat | 0.77 | 55.0 | 5.07e-01 | 72.8% | 69.8% |
| 3988872 | 211.1.1.8 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › CppA_N | 0.74 | 30.0 | 4.41e-01 | 71.6% | 84.3% |
| 4958430 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.69 | 49.0 | 4.28e-01 | 73.5% | 66.7% |
| 3591041 | 211.1.1.1 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase | 0.67 | 29.0 | 4.41e-01 | 74.1% | 100.0% |
| 5069234 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.67 | 46.0 | 4.55e-01 | 70.4% | 66.5% |
| 3633420 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.65 | 47.0 | 4.24e-01 | 74.1% | 65.0% |
| 3989366 | 211.1.1.1 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase | 0.65 | 30.0 | 4.24e-01 | 77.2% | 93.3% |
| 5021444 | 316.1.1.21 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit | 0.64 | 46.0 | 4.68e-01 | 73.5% | 81.9% |
| 3721514 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.64 | 46.0 | 4.07e-01 | 72.2% | 95.1% |
| 3281252 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.64 | 41.0 | 3.67e-01 | 71.0% | 47.3% |
| 4944306 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.63 | 44.0 | 4.29e-01 | 70.4% | 75.4% |
| 5076537 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.62 | 43.0 | 4.13e-01 | 70.4% | 65.8% |
| 3722297 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.62 | 28.0 | 3.91e-01 | 75.9% | 89.3% |
| 4978683 | 211.1.1.7 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase_4 | 0.61 | 28.0 | 4.04e-01 | 75.3% | 93.3% |
| 5078964 | 4272.1.1.1 ↗ | a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa | 0.57 | 35.0 | 3.85e-01 | 80.9% | 73.3% |
| 5023105 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.55 | 42.0 | 4.25e-01 | 79.6% | 85.0% |
| 3195886 | 316.1.1.56 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PF26128 | 0.54 | 45.0 | 3.51e-01 | 89.5% | 51.1% |
| 4998245 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.51 | 41.0 | 4.24e-01 | 85.8% | 91.0% |
| 3632181 | 316.1.1.56 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PF26128 | 0.50 | 42.0 | 4.05e-01 | 89.5% | 86.5% |
| 3630261 | 316.1.1.16 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DZF_N | 0.50 | 40.0 | 3.56e-01 | 83.3% | 88.7% |
| 5035507 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.50 | 44.0 | 4.00e-01 | 96.3% | 93.2% |
D3
high
residues 325-425
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12629.14 best | Pox_polyA_pol_C | 139.8 | 1.60e-40 | 100.0% | 49.5% |
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1je0C00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.64 | 43.0 | 3.33e-01 | 77.2% | 30.4% |
| 5cygB00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.64 | 47.0 | 3.40e-01 | 83.2% | 27.9% |
| 4wcwA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.64 | 51.0 | 4.98e-01 | 86.1% | 81.1% |
| 2fclA00 | 3.30.460.40 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › | 0.63 | 51.0 | 4.43e-01 | 88.1% | 80.1% |
| 1o22A00 | 3.90.1000.10 | Alpha Beta › Alpha-Beta Complex › Orphan Protein Tm0875; Chain: A; › Hypothetical protein TM0875 | 0.63 | 52.0 | 4.58e-01 | 90.1% | 93.3% |
| 4ipeB02 | 3.30.230.80 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.63 | 44.0 | 3.79e-01 | 73.3% | 97.0% |
| 2id1A01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.62 | 50.0 | 4.98e-01 | 85.1% | 83.7% |
| 2h8gA00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.62 | 44.0 | 3.28e-01 | 73.3% | 76.4% |
| 3r6aB00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.60 | 44.0 | 4.17e-01 | 76.2% | 100.0% |
| 3wfoA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.60 | 48.0 | 4.16e-01 | 87.1% | 65.0% |
| 1r89A02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.59 | 45.0 | 4.23e-01 | 83.2% | 78.1% |
| 5i41B00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.58 | 33.0 | 4.01e-01 | 97.0% | 85.1% |
| 8aidA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.58 | 45.0 | 4.19e-01 | 83.2% | 89.1% |
| 4mchA00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.57 | 47.0 | 3.60e-01 | 90.1% | 89.7% |
| 3h37A01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.57 | 45.0 | 4.07e-01 | 86.1% | 77.9% |
| 3vl9B00 | 2.60.120.180 | Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain | 0.57 | 51.0 | 4.00e-01 | 100.0% | 77.8% |
| 2r5vB02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.57 | 43.0 | 3.54e-01 | 81.2% | 92.3% |
| 3gm5A00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.57 | 44.0 | 3.89e-01 | 83.2% | 95.4% |
| 3upsA00 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.56 | 44.0 | 4.30e-01 | 82.2% | 78.7% |
| 1sp8C01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.56 | 44.0 | 3.75e-01 | 86.1% | 90.3% |
| 2hn1A01 | 3.30.460.20 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › CorA soluble domain-like | 0.56 | 45.0 | 4.05e-01 | 86.1% | 90.8% |
| 1cjxA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.56 | 44.0 | 3.91e-01 | 84.2% | 89.3% |
| 1v4nA00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.55 | 39.0 | 2.89e-01 | 72.3% | 74.4% |
| 1ou5A01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.55 | 43.0 | 3.91e-01 | 85.1% | 66.4% |
| 3rriA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.55 | 44.0 | 4.03e-01 | 85.1% | 100.0% |
| 4bl8B03 | 3.30.1360.230 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Sufu, C-terminal domain | 0.54 | 39.0 | 3.65e-01 | 76.2% | 95.5% |
| 1nlrA00 | 2.60.120.180 | Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain | 0.54 | 47.0 | 3.72e-01 | 100.0% | 59.5% |
| 1miwA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.54 | 44.0 | 4.01e-01 | 89.1% | 71.6% |
| 6k5gA01 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.54 | 42.0 | 3.24e-01 | 88.1% | 98.5% |
| 3bqxA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.53 | 42.0 | 3.81e-01 | 85.1% | 97.8% |
| 4g41A00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.53 | 43.0 | 3.35e-01 | 91.1% | 93.6% |
| 5c68A00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.53 | 40.0 | 3.91e-01 | 80.2% | 100.0% |
| 1zswA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.53 | 44.0 | 3.63e-01 | 90.1% | 82.0% |
| 3rmuA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.53 | 41.0 | 3.79e-01 | 85.1% | 97.8% |
| 7jw2A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.52 | 46.0 | 3.63e-01 | 99.0% | 88.1% |
| 2ei0A02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.51 | 43.0 | 3.79e-01 | 93.1% | 94.7% |
| 1cjxB02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.51 | 43.0 | 3.51e-01 | 96.0% | 98.5% |
| 2rk9B00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.50 | 40.0 | 3.83e-01 | 86.1% | 100.0% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1179386 | 4945.1.1.1 ↗ | a+b complex topology › C-terminal a+b domain in Poly(A) polymerase catalytic subunit › C-terminal a+b domain in Poly(A) polymerase catalytic subunit › C-terminal a+b domain in Poly(A) polymerase catalytic subunit › Pox_polyA_pol_C | 0.98 | 95.0 | 7.52e-01 | 100.0% | 56.8% |
| 4996047 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.69 | 47.0 | 4.48e-01 | 70.3% | 100.0% |
| 1387680 | 211.1.1.1 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase | 0.65 | 36.0 | 4.58e-01 | 70.3% | 98.2% |
| 3605429 | 7579.1.1.51 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF676 | 0.62 | 47.0 | 3.25e-01 | 81.2% | 44.6% |
| 4283597 | 211.1.1.1 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase | 0.62 | 37.0 | 4.40e-01 | 70.3% | 98.3% |
| 1160810 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.61 | 36.0 | 4.30e-01 | 74.3% | 95.1% |
| 3280391 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.61 | 39.0 | 4.49e-01 | 70.3% | 92.9% |
| 4930190 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.61 | 47.0 | 4.23e-01 | 84.2% | 74.5% |
| 5043316 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.60 | 47.0 | 4.13e-01 | 84.2% | 73.5% |
| 3605008 | 316.1.1.5 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RsfS | 0.60 | 48.0 | 3.84e-01 | 87.1% | 44.9% |
| 4146108 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.60 | 46.0 | 4.47e-01 | 84.2% | 73.0% |
| 4495995 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.60 | 47.0 | 4.35e-01 | 85.1% | 68.5% |
| 1160787 | 211.1.1.24 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Ble-like_N | 0.60 | 37.0 | 4.27e-01 | 71.3% | 91.2% |
| 3703821 | 7579.1.1.51 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF676 | 0.60 | 46.0 | 3.21e-01 | 82.2% | 48.5% |
| 5069373 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.59 | 46.0 | 4.23e-01 | 84.2% | 71.9% |
| 5010658 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.59 | 46.0 | 4.22e-01 | 84.2% | 71.9% |
| 3385505 | 316.1.1.5 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RsfS | 0.59 | 48.0 | 4.74e-01 | 87.1% | 87.6% |
| 5054759 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.59 | 46.0 | 4.16e-01 | 84.2% | 75.7% |
| 4948009 | 316.1.1.81 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › tRNA_NucTransf2 | 0.59 | 46.0 | 4.05e-01 | 84.2% | 68.0% |
| 4278249 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.59 | 46.0 | 4.19e-01 | 84.2% | 71.1% |
| 4982804 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.59 | 46.0 | 4.01e-01 | 84.2% | 65.8% |
| 5000046 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.58 | 46.0 | 4.10e-01 | 85.1% | 68.3% |
| 5033365 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.58 | 45.0 | 4.05e-01 | 84.2% | 73.8% |
| 3960020 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.57 | 46.0 | 3.96e-01 | 88.1% | 63.6% |
| 4436060 | 211.1.1.10 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase_5 | 0.57 | 44.0 | 4.08e-01 | 82.2% | 98.5% |
| 4972768 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.57 | 49.0 | 3.64e-01 | 98.0% | 69.1% |
| 3950526 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.57 | 45.0 | 3.97e-01 | 88.1% | 65.6% |
| 4968276 | 316.1.1.18 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii | 0.57 | 49.0 | 3.98e-01 | 97.0% | 82.5% |
| 3839787 | 316.1.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol | 0.57 | 45.0 | 4.08e-01 | 88.1% | 72.4% |
| 5030443 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.56 | 45.0 | 4.19e-01 | 87.1% | 76.2% |
| 3950089 | 2011.2.1.1 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PNP_UDP_1 | 0.56 | 47.0 | 3.40e-01 | 93.1% | 83.6% |
| 4073610 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.56 | 36.0 | 3.52e-01 | 91.1% | 57.4% |
| 3508699 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.56 | 43.0 | 3.84e-01 | 85.1% | 87.1% |
| 1842561 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.56 | 31.0 | 3.44e-01 | 72.3% | 68.4% |
| 3567876 | 316.1.1.20 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › OAS1_C | 0.55 | 43.0 | 3.64e-01 | 85.1% | 80.0% |
| 3424253 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 44.0 | 3.77e-01 | 88.1% | 69.4% |
| 3729454 | 327.5.1.5 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_3 | 0.55 | 48.0 | 4.48e-01 | 99.0% | 94.6% |
| 4583055 | 316.1.1.11 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › GrpB | 0.55 | 48.0 | 4.18e-01 | 99.0% | 81.9% |
| 4669167 | 2003.1.5.51 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TPMT | 0.55 | 43.0 | 3.45e-01 | 86.1% | 51.0% |
| 3676946 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 35.0 | 2.70e-01 | 82.2% | 29.4% |
| 4968794 | 2011.2.1.6 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › tRNA_deacylase | 0.52 | 45.0 | 3.77e-01 | 99.0% | 94.1% |
| 4968566 | 2003.1.9.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF | 0.52 | 45.0 | 3.70e-01 | 99.0% | 88.7% |
| 4955961 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.51 | 41.0 | 2.95e-01 | 88.1% | 98.1% |
D4
medium
residues 267-320_426-451
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12629.14 best | Pox_polyA_pol_C | 67.4 | 2.50e-18 | 65.0% | 25.2% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4gtnA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.61 | 39.0 | 4.05e-01 | 91.3% | 70.3% |
| 4p3gD00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.58 | 48.0 | 3.68e-01 | 92.5% | 83.1% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 47.0 | 4.42e-01 | 92.5% | 84.3% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 48.0 | 4.29e-01 | 96.2% | 77.8% |
| 4ezbA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 47.0 | 4.17e-01 | 92.5% | 94.9% |
| 4muoA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.55 | 35.0 | 3.71e-01 | 88.7% | 73.6% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 42.0 | 3.53e-01 | 83.7% | 50.7% |
| 3busB00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 41.0 | 2.92e-01 | 81.2% | 95.5% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.54 | 44.0 | 3.92e-01 | 92.5% | 61.2% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.54 | 43.0 | 4.25e-01 | 87.5% | 86.7% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.53 | 41.0 | 4.07e-01 | 91.3% | 82.4% |
| 4b6iA00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 43.0 | 4.06e-01 | 100.0% | 73.0% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 43.0 | 3.64e-01 | 91.3% | 94.2% |
| 3bulA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.52 | 41.0 | 4.01e-01 | 88.7% | 81.6% |
| 5hayA02 | 1.25.40.440 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain | 0.51 | 34.0 | 3.50e-01 | 88.7% | 72.2% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5011112 | 7516.1.1.79 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_trans_2_3 | 0.68 | 46.0 | 2.94e-01 | 70.0% | 61.1% |
| 3400457 | 109.4.1.839 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT | 0.64 | 43.0 | 3.49e-01 | 90.0% | 36.1% |
| 3631582 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.63 | 52.0 | 4.89e-01 | 91.3% | 92.0% |
| 4347666 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.61 | 49.0 | 3.90e-01 | 90.0% | 43.5% |
| 3182665 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.60 | 37.0 | 3.50e-01 | 70.0% | 50.5% |
| 4183024 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.60 | 48.0 | 3.98e-01 | 90.0% | 49.3% |
| 3930556 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.58 | 49.0 | 4.43e-01 | 96.2% | 95.7% |
| 5051636 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.56 | 44.0 | 3.77e-01 | 88.7% | 86.7% |
| 4574263 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.55 | 45.0 | 3.57e-01 | 91.3% | 43.5% |
| 3714949 | 109.46.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) | 0.55 | 39.0 | 3.20e-01 | 100.0% | 37.6% |
| 3238219 | 109.4.1.177 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd3 | 0.54 | 47.0 | 2.65e-01 | 98.8% | 18.7% |
| 3923777 | 5059.1.1.27 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › ChitinSynthase_IV_N | 0.53 | 47.0 | 2.98e-01 | 98.8% | 77.3% |
| 3543543 | 109.59.1.19 ↗ | alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Vps16_N | 0.52 | 41.0 | 4.06e-01 | 88.7% | 87.1% |
| 3960703 | 191.1.1.15 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_11 | 0.52 | 43.0 | 3.88e-01 | 97.5% | 84.2% |