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polymerase
Euk-VirFengkai_orbivirus
polymerase__YP_009163940__Fengkai_orbivirus__1692107
Identity
- Accession:
- YP_009163940 ↗
- Protein ID:
- polymerase
- Kingdom:
- euk
Quality
74.5
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Resentoviricetes›
Reovirales›
Sedoreoviridae›
Orbivirus›
Fengkai_orbivirus
TaxID: 1692107
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 241-387
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009158901__Chobar_Gorge_virus__1679172__D209-255_289-364
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05788.19 best | Orbi_VP1 | 255.3 | 1.40e-75 | 100.0% | 11.4% |
D2
medium
residues 1-37_949-978
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.50 | 37.0 | 2.79e-01 | 79.1% | 40.9% |
D3
medium
residues 72-226
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009047258__Umatilla_virus__40060__D70-244_849-867
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05788.19 best | Orbi_VP1 | 201.7 | 2.10e-59 | 100.0% | 11.9% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r7rA02 | 1.20.120.1390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 60.0 | 6.05e-01 | 91.6% | 88.9% |
| 1zv1A00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.65 | 23.0 | 3.64e-01 | 94.2% | 81.4% |
| 3fkeA01 | 1.10.8.950 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Filoviridae VP35, C-terminal inhibitory domain, helical subdomain | 0.55 | 25.0 | 3.67e-01 | 91.0% | 94.4% |
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.54 | 25.0 | 3.43e-01 | 89.0% | 87.0% |
| 2axyA00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.52 | 27.0 | 3.53e-01 | 72.3% | 100.0% |
D4
medium
residues 430-561_601-650
D5
medium
residues 562-600_722-839
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05788.19 best | Orbi_VP1 | 224.5 | 2.70e-66 | 75.8% | 9.1% |
| PF05788.19 | Orbi_VP1 | 69.9 | 1.30e-19 | 25.5% | 3.0% |
D6
medium
residues 1078-1116_1190-1260
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05788.19 best | Orbi_VP1 | 108.6 | 2.60e-31 | 67.3% | 5.6% |
| PF05788.19 | Orbi_VP1 | 45.3 | 3.40e-12 | 36.4% | 3.0% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r7rA07 | 3.30.230.140 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.78 | 62.0 | 6.05e-01 | 100.0% | 77.5% |
| 4xkjA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 40.0 | 3.80e-01 | 72.7% | 96.3% |
| 4xxhA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 43.0 | 4.03e-01 | 80.9% | 97.8% |
| 2cb0A01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.54 | 45.0 | 4.01e-01 | 91.8% | 93.7% |
| 5kfnA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.52 | 37.0 | 3.18e-01 | 74.5% | 63.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1173790 | 4962.1.1.3 ↗ | alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › Rotavirus_VP1 | 0.80 | 74.0 | 5.19e-01 | 100.0% | 54.4% |
| 1697853 | 4962.1.1.2 ↗ | alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 | 0.69 | 63.0 | 4.33e-01 | 100.0% | 51.2% |
| 3253767 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 35.0 | 3.11e-01 | 70.0% | 40.6% |
| 4128955 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.59 | 42.0 | 3.93e-01 | 98.2% | 61.5% |