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polymerase

Euk-Vir

Fengkai_orbivirus

polymerase__YP_009163940__Fengkai_orbivirus__1692107

Identity

Accession:
YP_009163940 ↗
Protein ID:
polymerase
Kingdom:
euk

Quality

74.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 241-387
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05788.19 best Orbi_VP1 255.3 1.40e-75 100.0% 11.4%
D2 medium residues 1-37_949-978
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4huqS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.50 37.0 2.79e-01 79.1% 40.9%
D3 medium residues 72-226
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05788.19 best Orbi_VP1 201.7 2.10e-59 100.0% 11.9%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2r7rA02 1.20.120.1390 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 60.0 6.05e-01 91.6% 88.9%
1zv1A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.65 23.0 3.64e-01 94.2% 81.4%
3fkeA01 1.10.8.950 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Filoviridae VP35, C-terminal inhibitory domain, helical subdomain 0.55 25.0 3.67e-01 91.0% 94.4%
2b8iA00 1.20.1280.100 Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain 0.54 25.0 3.43e-01 89.0% 87.0%
2axyA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.52 27.0 3.53e-01 72.3% 100.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5046473 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.59 28.0 3.65e-01 96.1% 77.8%
D4 medium residues 430-561_601-650
PDB
D5 medium residues 562-600_722-839
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05788.19 best Orbi_VP1 224.5 2.70e-66 75.8% 9.1%
PF05788.19 Orbi_VP1 69.9 1.30e-19 25.5% 3.0%
D6 medium residues 1078-1116_1190-1260
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05788.19 best Orbi_VP1 108.6 2.60e-31 67.3% 5.6%
PF05788.19 Orbi_VP1 45.3 3.40e-12 36.4% 3.0%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2r7rA07 3.30.230.140 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.78 62.0 6.05e-01 100.0% 77.5%
4xkjA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 40.0 3.80e-01 72.7% 96.3%
4xxhA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 43.0 4.03e-01 80.9% 97.8%
2cb0A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.54 45.0 4.01e-01 91.8% 93.7%
5kfnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.52 37.0 3.18e-01 74.5% 63.8%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1173790 4962.1.1.3 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › Rotavirus_VP1 0.80 74.0 5.19e-01 100.0% 54.4%
1697853 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.69 63.0 4.33e-01 100.0% 51.2%
3253767 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.60 35.0 3.11e-01 70.0% 40.6%
4128955 212.1.1.8 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P 0.59 42.0 3.93e-01 98.2% 61.5%