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polymerase

Euk-Vir

White_sucker_hepatitis_B_virus

polymerase__YP_009165599__White_sucker_hepatitis_B_virus__1690672

Identity

Accession:
YP_009165599 ↗
Protein ID:
polymerase
Kingdom:
euk

Quality

69.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 546-626
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00336.24 best DNA_pol_viral_C 49.0 7.30e-13 92.6% 24.1%
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.76 39.0 4.12e-01 98.8% 56.2%
2g3kA00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.74 65.0 6.20e-01 98.8% 98.9%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.73 64.0 6.02e-01 98.8% 96.0%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.69 52.0 5.00e-01 82.7% 100.0%
2ebzA02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.67 58.0 5.89e-01 97.5% 100.0%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 57.0 5.04e-01 98.8% 96.0%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.66 46.0 5.00e-01 72.8% 100.0%
1dtoA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.65 51.0 4.79e-01 86.4% 96.1%
7wf8B01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.65 56.0 4.92e-01 97.5% 65.3%
3llkA01 1.20.120.1960 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › QSOX sulfhydryl oxidase domain 0.64 55.0 5.21e-01 97.5% 86.7%
4dvyP03 1.20.120.1270 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CagA exotoxin domain III 0.64 56.0 4.48e-01 98.8% 50.0%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 44.0 3.70e-01 74.1% 66.2%
3fajA00 1.20.120.950 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 0.60 50.0 4.79e-01 100.0% 99.0%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.59 52.0 4.24e-01 100.0% 79.5%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.58 40.0 3.94e-01 71.6% 100.0%
4nt1A00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.58 49.0 3.83e-01 100.0% 80.0%
1nu7D01 1.20.120.750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 0.57 41.0 3.58e-01 77.8% 88.9%
1irxA05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.56 48.0 4.62e-01 96.3% 87.1%
1ls1A01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.55 47.0 4.59e-01 97.5% 95.5%
3s0xA01 1.20.120.1220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 48.0 3.97e-01 97.5% 93.9%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.54 44.0 4.32e-01 88.9% 95.3%
1oqcA00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.54 46.0 4.20e-01 98.8% 75.9%
1eg3A03 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 42.0 4.14e-01 88.9% 93.4%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 3.48e-01 96.3% 62.2%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.53 39.0 3.48e-01 79.0% 86.2%
2a0uB01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.53 45.0 3.70e-01 100.0% 57.5%
3kevA02 1.10.238.200 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Cullin, PONY binding domain 0.52 41.0 3.96e-01 93.8% 75.8%
4esjA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.90e-01 82.7% 82.2%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.52 36.0 3.67e-01 75.3% 74.4%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.52 35.0 2.90e-01 70.4% 52.6%
2r18A02 1.10.8.880 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Birnavirus VP3 protein, domain 2 0.52 35.0 3.97e-01 70.4% 100.0%
1wgwA00 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.52 43.0 4.14e-01 98.8% 87.9%
3nskB00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.51 39.0 3.85e-01 86.4% 88.0%
1sfuA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 4.10e-01 88.9% 95.7%
2f33A03 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.50 37.0 3.72e-01 81.5% 85.1%
3woyA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.50 38.0 2.76e-01 82.7% 38.6%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3936602 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.82 70.0 7.26e-01 98.8% 98.7%
3929262 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 67.0 6.98e-01 97.5% 98.7%
3824050 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.78 68.0 6.70e-01 100.0% 90.6%
3924867 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.78 67.0 6.94e-01 98.8% 100.0%
3273269 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 70.0 6.82e-01 100.0% 100.0%
3933762 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 66.0 6.83e-01 97.5% 100.0%
3924778 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 67.0 6.78e-01 100.0% 97.5%
3529289 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 65.0 6.71e-01 96.3% 100.0%
3926781 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 66.0 6.72e-01 100.0% 96.2%
4995268 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.76 67.0 5.75e-01 97.5% 70.8%
3737899 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 67.0 6.74e-01 100.0% 97.5%
3937630 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 65.0 6.74e-01 97.5% 100.0%
1893003 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 65.0 6.62e-01 98.8% 97.4%
3936725 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 65.0 6.69e-01 96.3% 100.0%
3926140 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 64.0 6.63e-01 97.5% 100.0%
3927913 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 64.0 6.61e-01 96.3% 100.0%
3925035 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.75 64.0 6.61e-01 96.3% 100.0%
3934191 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 64.0 6.50e-01 98.8% 97.5%
3903902 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 65.0 6.55e-01 100.0% 98.8%
3274224 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 60.0 6.25e-01 87.7% 96.0%
3927690 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 65.0 6.53e-01 100.0% 98.8%
3931351 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 65.0 6.55e-01 100.0% 100.0%
3933421 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 61.0 6.30e-01 96.3% 100.0%
3929753 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 62.0 6.37e-01 95.1% 100.0%
3254770 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 65.0 6.01e-01 100.0% 84.8%
3937707 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 64.0 6.53e-01 100.0% 98.8%
3927489 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 61.0 6.30e-01 96.3% 100.0%
3934727 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 65.0 6.43e-01 100.0% 96.5%
2757013 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.72 65.0 6.43e-01 100.0% 97.6%
3924758 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.72 63.0 6.38e-01 100.0% 98.8%
3939414 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.71 62.0 6.32e-01 98.8% 98.8%
3924491 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.71 59.0 6.09e-01 96.3% 100.0%
3845825 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.70 62.0 6.24e-01 100.0% 100.0%
4943145 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.69 61.0 5.82e-01 98.8% 100.0%
3663674 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 57.0 4.65e-01 98.8% 81.8%
5079648 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.66 60.0 5.81e-01 100.0% 94.4%
5051451 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.66 59.0 5.74e-01 98.8% 90.0%
3968228 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.64 47.0 4.14e-01 79.0% 95.2%
5074496 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.64 57.0 5.81e-01 98.8% 100.0%
5047749 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.64 55.0 5.49e-01 98.8% 98.8%
5083350 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.63 54.0 4.85e-01 98.8% 95.0%
1888148 3432.1.1.1 alpha bundles › Minor nucleoprotein VP30 C-terminal domain › Minor nucleoprotein VP30 C-terminal domain › Minor nucleoprotein VP30 C-terminal domain › Transcript_VP30 0.62 54.0 4.60e-01 100.0% 82.7%
3824339 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 46.0 3.70e-01 80.2% 91.5%
2577335 7110.1.1.1 alpha arrays › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › DUF463 0.61 48.0 4.00e-01 82.7% 69.9%
3446746 631.1.1.1 alpha arrays › Glycolipid transfer protein, GLTP › Glycolipid transfer protein, GLTP › Glycolipid transfer protein, GLTP › GLTP 0.60 51.0 3.89e-01 98.8% 81.0%
3606790 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.60 41.0 4.00e-01 71.6% 78.9%
3166146 7110.1.1.1 alpha arrays › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › DUF463 0.59 46.0 3.86e-01 82.7% 70.4%
3592194 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.59 41.0 3.02e-01 71.6% 27.1%
366446 108.1.1.8 alpha arrays › EF-hand › EF-hand-related › EF-hand › S_100 0.59 46.0 4.50e-01 88.9% 92.5%
3758995 604.1.1.67 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.58 40.0 3.67e-01 70.4% 88.6%
4025134 631.1.1.1 alpha arrays › Glycolipid transfer protein, GLTP › Glycolipid transfer protein, GLTP › Glycolipid transfer protein, GLTP › GLTP 0.57 48.0 3.70e-01 100.0% 81.0%
3725437 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 40.0 3.71e-01 75.3% 57.3%
3938862 604.1.1.98 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 0.56 39.0 3.57e-01 72.8% 85.5%
4105091 101.8.1.2 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.56 47.0 3.63e-01 96.3% 43.9%
3389671 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 39.0 3.12e-01 76.5% 54.7%
4354193 101.8.1.2 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.55 46.0 3.66e-01 96.3% 44.0%
3389844 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.54 42.0 3.62e-01 87.7% 52.6%
4943201 181.1.1.32 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54 0.54 44.0 4.37e-01 91.4% 95.3%
4632307 101.8.1.2 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.53 45.0 3.80e-01 95.1% 55.7%
3504009 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.53 43.0 4.25e-01 93.8% 89.4%
3670774 4957.1.1.0 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.52 36.0 3.18e-01 72.8% 78.4%
415002 108.1.1.8 alpha arrays › EF-hand › EF-hand-related › EF-hand › S_100 0.51 39.0 3.82e-01 86.4% 87.1%
3332798 241.15.1.0 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.51 36.0 2.92e-01 76.5% 97.1%
3542516 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.51 39.0 3.70e-01 88.9% 79.0%
3420624 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.50 39.0 3.63e-01 84.0% 74.3%
3450793 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.50 41.0 3.46e-01 90.1% 57.9%
D2 medium residues 54-75_106-130_359-396
PDB
D3 medium residues 76-105_426-465
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ol8B02 3.10.10.10 Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › HIV Type 1 Reverse Transcriptase, subunit A, domain 1 0.62 53.0 4.40e-01 92.9% 98.3%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3935908 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.83 49.0 3.96e-01 98.6% 33.6%
3265942 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 62.0 4.56e-01 90.0% 57.1%
3787710 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 66.0 4.28e-01 100.0% 54.4%
3927736 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.71 66.0 4.41e-01 100.0% 56.7%
4618808 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.71 66.0 4.29e-01 100.0% 58.5%
3271795 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 64.0 4.20e-01 100.0% 56.5%
3785231 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 65.0 4.14e-01 100.0% 52.7%
2765413 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 65.0 4.22e-01 100.0% 55.3%
3295157 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 64.0 4.17e-01 100.0% 59.6%
3932186 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 64.0 4.66e-01 100.0% 94.9%
4096485 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 62.0 4.12e-01 98.6% 60.0%
3926952 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 63.0 4.22e-01 100.0% 56.4%
3252343 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 63.0 4.16e-01 100.0% 58.8%
3737895 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 63.0 4.20e-01 100.0% 62.0%
3427907 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.69 63.0 4.16e-01 100.0% 59.2%
3930235 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.13e-01 100.0% 58.1%
3216767 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.05e-01 100.0% 54.7%
3516732 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.41e-01 100.0% 79.5%
3510717 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.14e-01 100.0% 60.0%
3927796 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 63.0 4.14e-01 100.0% 57.4%
3938608 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.08e-01 100.0% 62.2%
3927691 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 63.0 4.17e-01 100.0% 60.8%
3925602 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.67 62.0 4.12e-01 100.0% 58.8%
3504869 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.67 61.0 4.25e-01 100.0% 50.0%
3937440 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.66 61.0 4.02e-01 100.0% 58.5%
3936601 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.64 58.0 3.85e-01 100.0% 58.1%
3923429 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 53.0 3.69e-01 100.0% 56.4%
3937811 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.54 50.0 3.82e-01 100.0% 74.0%
D4 medium residues 131-173_348-358
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1z8rA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 50.0 5.36e-01 77.8% 97.6%
2hrvA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.64 46.0 4.90e-01 94.4% 95.5%
2eqnA01 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.63 48.0 4.17e-01 85.2% 67.8%
1arbA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.62 52.0 3.91e-01 96.3% 76.6%
3bchA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.62 41.0 2.86e-01 70.4% 82.3%
1jg5A00 3.30.1410.10 Alpha Beta › 2-Layer Sandwich › Gtp Cyclohydrolase I Feedback Regulatory Protein; Chain: K › GTP cyclohydrolase I feedback regulatory protein GFRP 0.61 44.0 3.96e-01 81.5% 66.3%
1vi6C01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.61 42.0 2.91e-01 72.2% 83.0%
1shyA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.59 49.0 4.08e-01 96.3% 79.4%
4f4oC03 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.58 47.0 4.12e-01 96.3% 91.0%
2xxlA01 3.30.1640.30 Alpha Beta › 2-Layer Sandwich › mini-chromosome maintenance (MCM) complex, chain A, domain 1 › 0.58 40.0 3.56e-01 72.2% 85.9%
3ftbA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 42.0 3.42e-01 81.5% 50.9%
4pfyA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.56 46.0 3.48e-01 96.3% 54.4%
3zs6A02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.55 45.0 3.62e-01 98.1% 77.9%
4u7mA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 41.0 3.53e-01 87.0% 93.7%
4ab7H02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 44.0 3.30e-01 94.4% 75.0%
6swc801 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.54 41.0 3.35e-01 88.9% 49.1%
2ed8A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 42.0 3.63e-01 87.0% 98.8%
2pliA00 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.54 40.0 3.59e-01 87.0% 97.6%
7clyA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 37.0 2.71e-01 81.5% 92.0%
3i8bA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 40.0 2.77e-01 94.4% 22.7%
2w1nA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 37.0 3.37e-01 85.2% 100.0%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4882551 1.1.5.5 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pico_P2A 0.69 56.0 4.13e-01 92.6% 33.6%
4078587 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.69 55.0 3.38e-01 88.9% 17.5%
3722122 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.67 50.0 3.13e-01 83.3% 16.6%
3622749 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.65 55.0 3.42e-01 96.3% 19.4%
3798149 601.23.1.0 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.64 54.0 3.39e-01 96.3% 20.3%
4454397 2007.1.17.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Resistance protein Tm-1 second domain › UPF0261_C 0.62 52.0 3.47e-01 96.3% 44.4%
4968151 101.1.2.70 alpha arrays › HTH › HTH › winged helix domain › PqqD 0.61 44.0 3.61e-01 77.8% 45.7%
4854162 2007.6.1.1 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › Ribosomal_S2 0.60 40.0 2.78e-01 70.4% 77.7%
5041140 217.2.1.1 a+b complex topology › FAD-binding domain-like › CorC/HlyC domain-like › CorC/HlyC domain-like › CorC_HlyC 0.59 46.0 4.01e-01 90.7% 96.7%
4194516 601.23.1.0 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.58 45.0 2.91e-01 88.9% 18.6%
3710176 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.58 49.0 3.04e-01 100.0% 37.6%
4997049 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.56 45.0 4.25e-01 98.1% 92.9%
5056023 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.55 43.0 3.61e-01 90.7% 81.0%
3786487 11.1.1.1099 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF28268 0.55 41.0 3.75e-01 87.0% 92.5%
3905651 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 40.0 3.94e-01 85.2% 73.3%
3316007 12.1.1.5 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amyl_C2 0.54 41.0 4.26e-01 88.9% 93.8%
3164975 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.54 40.0 3.74e-01 87.0% 80.0%
4659014 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.53 41.0 3.34e-01 87.0% 82.3%
3293955 2006.1.1.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.53 43.0 2.78e-01 100.0% 47.9%
3425743 359.1.1.1 few secondary structure elements › Bowman-Birk inhibitor, BBI-like › Bowman-Birk inhibitor, BBI-like › Bowman-Birk inhibitor, BBI-like › Bowman-Birk_leg 0.52 37.0 3.69e-01 81.5% 83.3%
3923079 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.52 41.0 3.50e-01 90.7% 95.8%
3268160 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.51 40.0 3.54e-01 94.4% 71.1%
4034501 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.51 39.0 3.56e-01 94.4% 83.5%
4028923 2003.1.3.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain 0.50 38.0 2.28e-01 96.3% 26.3%
D5 medium residues 397-425_466-545
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00078.33 best RVT_1 32.7 9.50e-08 75.2% 38.0%
D6 medium residues 632-747
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00336.24 best DNA_pol_viral_C 56.5 3.70e-15 97.4% 43.1%