←Back to structures

polymerase

Euk-Vir

Bluegill_hepatitis_B_virus

polymerase__YP_009259541__Bluegill_hepatitis_B_virus__2169918

Identity

Accession:
YP_009259541 ↗
Protein ID:
polymerase
Kingdom:
euk

Quality

71.8 mean pLDDT

Taxonomy

Pararnavirae› Artverviricota› Revtraviricetes› Blubervirales› Hepadnaviridae› Metahepadnavirus› Bluegill_hepatitis_B_virus

TaxID: 2169918

Cluster

View cluster (15 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 631-727
PDB
Domain cluster: rep: OQ808965.1__WGH50389.1__FNU3_71__00071__D62-192
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00336.24 best DNA_pol_viral_C 86.6 2.50e-24 100.0% 41.9%
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1f21A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.85 79.0 6.66e-01 100.0% 86.8%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 63.0 5.26e-01 100.0% 72.2%
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 61.0 5.28e-01 100.0% 67.8%
1asuA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.66 60.0 5.03e-01 100.0% 62.3%
6jdbA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 53.0 4.51e-01 86.6% 95.4%
2q2rA02 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.65 54.0 4.29e-01 91.8% 84.7%
2yhwA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 53.0 4.46e-01 88.7% 97.0%
4ijaA03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 52.0 4.49e-01 86.6% 96.7%
5cz2C00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 58.0 4.95e-01 100.0% 63.2%
3id6A01 3.30.420.220 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.64 56.0 5.49e-01 100.0% 88.7%
3vovA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.63 51.0 4.38e-01 86.6% 97.4%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.63 56.0 4.12e-01 100.0% 75.6%
4ifeA02 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.63 56.0 4.28e-01 100.0% 85.0%
2hoeA03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 51.0 4.51e-01 91.8% 96.6%
3vglA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 50.0 4.12e-01 87.6% 97.7%
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.61 55.0 4.24e-01 100.0% 82.0%
3r8eA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 50.0 4.26e-01 90.7% 97.5%
3hrgA02 3.30.420.260 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, C-terminal domain 0.61 49.0 4.72e-01 96.9% 76.3%
3pdiA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.60 51.0 4.36e-01 91.8% 72.1%
3lm2A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 49.0 4.95e-01 89.7% 93.8%
1nmnA00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.59 53.0 4.95e-01 99.0% 87.5%
7essA01 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.59 53.0 4.78e-01 100.0% 87.1%
3t5tB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.57 48.0 3.47e-01 92.8% 92.0%
2xdqB01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.57 49.0 4.24e-01 92.8% 74.1%
2gupA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 46.0 4.62e-01 88.7% 97.9%
4ep4A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.57 52.0 4.31e-01 100.0% 86.1%
3ig4A01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.57 48.0 3.97e-01 91.8% 85.3%
5m1pB00 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.57 49.0 4.04e-01 100.0% 76.7%
3gpgA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.56 46.0 3.92e-01 89.7% 78.4%
2d1cA01 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.56 47.0 3.19e-01 93.8% 44.8%
3blvC00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.55 47.0 3.26e-01 94.8% 51.3%
1cnzA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.55 45.0 3.13e-01 92.8% 41.3%
6ldqA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 45.0 3.75e-01 91.8% 87.8%
3zm6A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.55 47.0 3.58e-01 93.8% 78.5%
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.54 45.0 3.14e-01 93.8% 50.4%
2xdqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.54 46.0 4.12e-01 92.8% 80.9%
3otgA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 44.0 3.52e-01 93.8% 92.0%
3okpA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 45.0 3.59e-01 91.8% 85.7%
1oe4A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.53 44.0 3.35e-01 92.8% 71.8%
3kzwA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 42.0 3.66e-01 88.7% 90.5%
4y97D00 1.10.3200.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › DNA Polymerase alpha, zinc finger 0.53 40.0 3.38e-01 83.5% 94.9%
1bqgA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.53 46.0 3.41e-01 97.9% 85.8%
5hn3A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.52 44.0 3.09e-01 94.8% 46.1%
3mnfA00 3.40.50.10900 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit 0.52 44.0 3.36e-01 93.8% 83.0%
7r7jA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.53e-01 92.8% 96.2%
1qlwA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 42.0 3.07e-01 93.8% 74.8%
1wywA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.52 42.0 3.36e-01 91.8% 64.4%
2o20A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 42.0 3.75e-01 88.7% 67.9%
6eudA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 43.0 3.65e-01 94.8% 99.4%
7jt8I02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.51 41.0 3.67e-01 88.7% 95.1%
5f5nA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.12e-01 93.8% 63.0%
2vptA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.51 43.0 3.42e-01 92.8% 90.0%
4huqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 39.0 2.91e-01 84.5% 41.2%
6ajpA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.51 40.0 3.20e-01 86.6% 75.2%
1o94A03 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 43.0 3.80e-01 96.9% 84.9%
3ottB02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.50 30.0 2.10e-01 82.5% 17.4%
2p9bA03 3.40.50.10910 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Amidohydrolase 0.50 39.0 3.61e-01 90.7% 64.5%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3262383 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.87 81.0 7.18e-01 100.0% 87.4%
3888095 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.86 80.0 7.00e-01 100.0% 86.4%
3643307 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.85 80.0 7.23e-01 100.0% 90.4%
3933233 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.83 76.0 6.83e-01 97.9% 90.0%
3924791 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.82 73.0 6.58e-01 94.8% 86.9%
5056410 2484.1.1.59 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.76 69.0 4.78e-01 100.0% 77.5%
5041805 2484.7.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Uncharacterized protein PF2046 › Uncharacterized protein PF2046 › DUF4152 0.72 64.0 5.10e-01 100.0% 61.0%
428031 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.66 60.0 5.31e-01 100.0% 72.3%
3600048 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.66 56.0 4.19e-01 93.8% 79.6%
2391702 2484.1.1.31 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Glucokinase 0.65 55.0 4.20e-01 93.8% 81.7%
None — 0.65 55.0 4.25e-01 93.8% 80.6%
3646441 2484.1.1.205 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27035 0.64 54.0 5.24e-01 99.0% 80.9%
3504836 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.63 58.0 4.54e-01 100.0% 48.5%
3958788 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 53.0 5.10e-01 93.8% 90.0%
4009809 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 53.0 4.89e-01 94.8% 91.2%
1102610 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 52.0 5.01e-01 93.8% 87.4%
5048941 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 47.0 4.72e-01 96.9% 81.0%
5024386 2484.4.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like 0.61 45.0 4.54e-01 89.7% 78.0%
4933243 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.61 55.0 4.53e-01 100.0% 86.9%
4936503 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 52.0 4.82e-01 92.8% 91.7%
4944932 2484.4.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like 0.59 51.0 4.90e-01 93.8% 84.4%
4587559 4263.2.1.0 ↗ a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain 0.59 34.0 3.78e-01 100.0% 72.0%
4324089 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.59 50.0 3.07e-01 91.8% 56.0%
4229035 2484.1.1.12 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Acetate_kinase 0.59 50.0 3.94e-01 92.8% 90.0%
5020876 2484.4.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like › Nitro_FeMo-Co 0.58 50.0 4.79e-01 93.8% 83.6%
5042478 2484.4.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like › Nitro_FeMo-Co 0.58 49.0 4.65e-01 94.8% 79.2%
4952128 2484.4.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like › Nitro_FeMo-Co 0.58 49.0 4.76e-01 93.8% 83.6%
4038287 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.58 52.0 4.69e-01 100.0% 88.1%
3920705 2005.1.1.7 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.58 49.0 3.55e-01 90.7% 88.8%
3403644 2005.1.1.7 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.58 48.0 3.52e-01 89.7% 97.6%
2623870 2484.1.1.44 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pox_A22 0.58 52.0 4.53e-01 100.0% 88.6%
4116094 2484.1.1.37 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.57 48.0 4.57e-01 92.8% 91.3%
4958926 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 48.0 4.70e-01 91.8% 85.7%
4071071 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.57 51.0 4.42e-01 100.0% 79.3%
4308615 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.57 50.0 4.55e-01 100.0% 88.1%
4156472 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.57 50.0 4.35e-01 99.0% 81.3%
4632327 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.56 50.0 4.39e-01 99.0% 84.1%
4928103 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.56 47.0 3.30e-01 92.8% 47.2%
4931426 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.56 46.0 3.84e-01 91.8% 95.0%
5003943 2484.4.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like › Nitro_FeMo-Co 0.56 48.0 4.64e-01 95.9% 86.4%
4220389 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.56 47.0 3.85e-01 92.8% 79.4%
4171807 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.56 50.0 4.24e-01 100.0% 75.0%
4118739 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.56 50.0 4.37e-01 99.0% 84.1%
4931231 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 46.0 3.69e-01 91.8% 56.5%
3789539 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.56 46.0 4.20e-01 91.8% 94.6%
4947633 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.55 45.0 3.83e-01 90.7% 94.1%
3732183 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.55 46.0 4.01e-01 92.8% 96.8%
3397477 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.55 45.0 3.98e-01 89.7% 95.9%
4091986 2484.1.1.37 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.55 46.0 4.41e-01 92.8% 91.3%
5008651 2484.4.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Nitrogenase accessory factor-like › Nitrogenase accessory factor-like › Nitro_FeMo-Co 0.55 46.0 4.65e-01 93.8% 96.0%
4961847 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.55 49.0 3.84e-01 100.0% 80.0%
3687529 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.55 45.0 3.81e-01 92.8% 89.1%
4661523 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.55 46.0 3.91e-01 93.8% 95.8%
4015641 7510.1.1.0 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like 0.55 46.0 4.02e-01 93.8% 96.0%
3270651 2005.1.1.7 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.55 44.0 3.12e-01 88.7% 88.6%
4197082 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.54 45.0 3.82e-01 92.8% 83.5%
4355370 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.54 48.0 4.25e-01 100.0% 80.7%
4973306 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.54 44.0 3.92e-01 89.7% 97.2%
5004320 2006.1.4.24 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_12 0.54 45.0 3.47e-01 92.8% 96.1%
3242107 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 45.0 3.92e-01 89.7% 80.7%
3721036 7604.1.1.1 ↗ a/b three-layered sandwiches › a/b domain in Acetophenone carboxylase (Apc) alpha subunit › a/b domain in Acetophenone carboxylase (Apc) alpha subunit › a/b domain in Acetophenone carboxylase (Apc) alpha subunit › Hydant_A_N 0.54 45.0 4.11e-01 93.8% 86.7%
4126066 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.54 47.0 4.19e-01 100.0% 82.8%
3636078 7604.1.1.0 ↗ a/b three-layered sandwiches › a/b domain in Acetophenone carboxylase (Apc) alpha subunit › a/b domain in Acetophenone carboxylase (Apc) alpha subunit › a/b domain in Acetophenone carboxylase (Apc) alpha subunit 0.53 45.0 4.12e-01 93.8% 91.5%
3383269 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 44.0 3.59e-01 91.8% 50.8%
4986553 2004.1.1.146 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.53 43.0 3.30e-01 91.8% 64.9%
1040170 2003.1.1.45 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › UDPG_MGDP_dh_N 0.52 46.0 3.71e-01 100.0% 58.9%
D2 medium residues 357-385_508-535
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.77 67.0 5.03e-01 100.0% 77.1%
5cqgA04 3.30.70.2630 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 54.0 4.58e-01 100.0% 91.5%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3934202 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.82 70.0 5.14e-01 94.7% 95.9%
3926633 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.81 72.0 5.00e-01 100.0% 71.4%
3643305 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.81 66.0 4.97e-01 89.5% 96.3%
3939861 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.77 67.0 5.31e-01 100.0% 97.5%
3947863 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.76 67.0 4.34e-01 100.0% 66.3%
3315278 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 51.0 3.98e-01 75.4% 80.8%
3567739 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.57 34.0 2.97e-01 93.0% 35.8%
D3 medium residues 536-627
PDB
Domain cluster: rep: polymerase__YP_009165599__White_sucker_hepatitis_B_virus__1690672__D546-626
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00336.24 best DNA_pol_viral_C 60.0 3.30e-16 97.8% 34.4%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2g3kA00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.72 59.0 5.89e-01 89.1% 100.0%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.67 47.0 4.64e-01 72.8% 100.0%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.66 46.0 4.08e-01 71.7% 92.4%
1dtoA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.66 49.0 4.74e-01 78.3% 98.0%
5t3wA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 52.0 4.55e-01 89.1% 81.8%
5dvwA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 51.0 4.58e-01 89.1% 86.4%
1xnfA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 48.0 3.53e-01 100.0% 96.9%
1ls1A01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.53 42.0 4.26e-01 88.0% 96.6%
4i5jA01 1.10.238.220 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.53 36.0 3.48e-01 71.7% 80.7%
3nnrA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 41.0 3.25e-01 90.2% 57.4%
3nskB00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.51 36.0 3.69e-01 77.2% 89.1%
3htkC01 1.20.120.1010 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 37.0 2.92e-01 77.2% 81.5%
1b4cA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.50 36.0 3.63e-01 77.2% 93.5%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3936602 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.82 64.0 7.00e-01 88.0% 100.0%
3824050 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.80 69.0 7.13e-01 96.7% 100.0%
3933762 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.80 62.0 6.74e-01 87.0% 100.0%
3929262 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.80 62.0 6.74e-01 87.0% 100.0%
3273269 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 65.0 6.63e-01 88.0% 100.0%
3937630 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 61.0 6.68e-01 87.0% 100.0%
3924867 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 61.0 6.67e-01 87.0% 100.0%
3926781 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 64.0 6.86e-01 92.4% 100.0%
3924778 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 64.0 6.82e-01 91.3% 100.0%
3925035 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.79 61.0 6.62e-01 85.9% 100.0%
3529289 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.78 60.0 6.59e-01 84.8% 100.0%
3930507 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.78 60.0 6.57e-01 87.0% 100.0%
3254770 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.78 66.0 6.31e-01 94.6% 80.0%
3936725 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 59.0 6.48e-01 84.8% 100.0%
3926140 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 59.0 6.44e-01 80.4% 100.0%
3737899 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 62.0 6.63e-01 90.2% 100.0%
3927690 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.77 62.0 6.60e-01 89.1% 100.0%
3903902 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 62.0 6.58e-01 89.1% 100.0%
3939414 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 62.0 6.54e-01 90.2% 100.0%
3274224 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 56.0 6.09e-01 77.2% 96.0%
3937707 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.76 61.0 6.53e-01 90.2% 100.0%
3924758 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.75 61.0 6.42e-01 90.2% 100.0%
3933421 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.75 57.0 6.23e-01 84.8% 100.0%
3934191 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 60.0 6.34e-01 89.1% 100.0%
3927489 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 57.0 6.21e-01 84.8% 100.0%
3929753 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 57.0 6.21e-01 83.7% 100.0%
3845825 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 59.0 6.27e-01 90.2% 100.0%
3934727 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.73 62.0 6.44e-01 91.3% 100.0%
3931852 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.72 58.0 6.12e-01 89.1% 100.0%
4943145 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.66 56.0 5.58e-01 94.6% 100.0%
3750635 2484.1.1.169 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.66 43.0 2.98e-01 70.7% 20.8%
1888148 3432.1.1.1 ↗ alpha bundles › Minor nucleoprotein VP30 C-terminal domain › Minor nucleoprotein VP30 C-terminal domain › Minor nucleoprotein VP30 C-terminal domain › Transcript_VP30 0.63 51.0 4.48e-01 89.1% 80.6%
5074496 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.63 50.0 5.33e-01 87.0% 100.0%
3504009 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 42.0 4.33e-01 81.5% 88.2%
415002 108.1.1.8 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › S_100 0.53 37.0 3.72e-01 73.9% 88.2%
3504302 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 34.0 3.38e-01 100.0% 61.0%
4105091 101.8.1.2 ↗ alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.52 43.0 3.45e-01 92.4% 47.0%
3598778 198.1.1.0 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.52 30.0 3.36e-01 91.3% 74.3%
3542516 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.50 36.0 3.56e-01 78.3% 78.1%
3393554 3350.1.1.1 ↗ alpha bundles › Peroxisomal biogenesis factor 3 › Peroxisomal biogenesis factor 3 › Peroxisomal biogenesis factor 3 › Peroxin-3 0.50 42.0 3.11e-01 98.9% 94.4%