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polymerase_basic_1_protein
Euk-VirWellfleet_Bay_virus
polymerase_basic_1_protein__YP_009110686__Wellfleet_Bay_virus__1566309
Identity
- Accession:
- YP_009110686 ↗
- Protein ID:
- polymerase_basic_1_protein
- Kingdom:
- euk
Quality
65.5
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Insthoviricetes›
Articulavirales›
Orthomyxoviridae›
Quaranjavirus›
Wellfleet_Bay_virus
TaxID: 1566309
Cluster
View cluster (14 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 56-150_175-194_248-302
Domain cluster:
representative
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1695458 | 304.48.1.7 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 | 0.81 | 77.0 | 5.43e-01 | 100.0% | 48.7% |
| 2850105 | 304.48.1.19 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Bunya_RdRp | 0.68 | 63.0 | 5.44e-01 | 100.0% | 83.8% |
| 2757968 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.57 | 49.0 | 4.49e-01 | 91.8% | 96.0% |
| 3938039 | 387.1.5.0 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like | 0.53 | 13.0 | 2.86e-01 | 75.9% | 100.0% |
D2
medium
residues 151-174_195-247
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.65 | 53.0 | 3.75e-01 | 88.3% | 93.3% |
| 3hm2A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.64 | 47.0 | 3.62e-01 | 77.9% | 45.0% |
| 3k8aB00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.62 | 44.0 | 4.02e-01 | 96.1% | 55.3% |
| 1l3iA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 42.0 | 3.18e-01 | 70.1% | 42.2% |
| 1v1qA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.60 | 42.0 | 3.80e-01 | 96.1% | 52.7% |
| 3icaB00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.59 | 42.0 | 3.14e-01 | 75.3% | 57.8% |
| 2yxdA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 39.0 | 3.06e-01 | 72.7% | 41.9% |
| 3e05B00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 38.0 | 2.89e-01 | 70.1% | 40.6% |
| 1ffyA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.55 | 39.0 | 2.52e-01 | 75.3% | 73.4% |
| 1nbwA02 | 3.90.470.30 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Coenzyme B12-Dependent Enzyme linker domain | 0.55 | 40.0 | 3.32e-01 | 77.9% | 58.7% |
| 2l6mA00 | 3.30.160.400 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.55 | 37.0 | 3.44e-01 | 70.1% | 53.5% |
| 2lxxA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.55 | 37.0 | 3.04e-01 | 71.4% | 61.8% |
| 3ddcB00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 41.0 | 3.48e-01 | 83.1% | 78.2% |
| 3fhwA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.54 | 36.0 | 3.38e-01 | 96.1% | 54.5% |
| 6qcbA00 | 2.40.70.10 | Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases | 0.53 | 28.0 | 2.68e-01 | 87.0% | 38.1% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.52 | 42.0 | 2.72e-01 | 94.8% | 88.1% |
| 1av4A03 | 2.70.98.20 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain | 0.52 | 40.0 | 2.55e-01 | 83.1% | 38.2% |
| 4ec7A00 | 2.10.90.10 | Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines | 0.50 | 36.0 | 3.27e-01 | 85.7% | 54.6% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4351239 | 4967.1.1.6 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 | 0.71 | 43.0 | 3.59e-01 | 87.0% | 36.2% |
| 4666185 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.67 | 50.0 | 3.08e-01 | 77.9% | 48.2% |
| 4983372 | 304.48.1.20 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1 | 0.64 | 51.0 | 3.60e-01 | 88.3% | 90.4% |
| 4223395 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.63 | 48.0 | 3.01e-01 | 81.8% | 46.8% |
| 3601924 | 511.1.1.0 ↗ | beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain | 0.62 | 50.0 | 3.79e-01 | 85.7% | 44.0% |
| 4635290 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.62 | 48.0 | 2.98e-01 | 81.8% | 49.1% |
| 4241274 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.62 | 46.0 | 2.86e-01 | 77.9% | 46.4% |
| 4126255 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.62 | 47.0 | 3.18e-01 | 80.5% | 30.9% |
| 4544858 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.62 | 47.0 | 2.91e-01 | 81.8% | 49.8% |
| 4361292 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.61 | 47.0 | 2.92e-01 | 83.1% | 49.1% |
| 4486052 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.60 | 47.0 | 3.00e-01 | 81.8% | 63.5% |
| 4951650 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.60 | 45.0 | 3.07e-01 | 79.2% | 60.8% |
| 4088089 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.59 | 44.0 | 2.93e-01 | 80.5% | 58.4% |
| 3739406 | 330.1.1.9 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dcr1-like_dsRNA-bd_dom | 0.58 | 42.0 | 3.80e-01 | 76.6% | 93.3% |
| 3707269 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.57 | 43.0 | 3.04e-01 | 79.2% | 60.0% |
| 4682218 | 3382.1.1.1 ↗ | alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt | 0.56 | 42.0 | 2.88e-01 | 83.1% | 64.3% |
| 4952838 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.56 | 39.0 | 2.73e-01 | 74.0% | 72.8% |
| 5072529 | 512.1.1.1 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st | 0.56 | 41.0 | 3.90e-01 | 76.6% | 68.9% |
| 3470394 | 3382.1.1.1 ↗ | alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt | 0.56 | 45.0 | 3.02e-01 | 92.2% | 76.9% |
| 4635289 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.55 | 41.0 | 2.64e-01 | 81.8% | 46.8% |
| 3220090 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.55 | 41.0 | 2.63e-01 | 84.4% | 81.9% |
| 4240255 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.55 | 43.0 | 3.74e-01 | 84.4% | 87.8% |
| 4305190 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 43.0 | 3.67e-01 | 87.0% | 86.9% |
| 4101594 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 43.0 | 3.75e-01 | 87.0% | 89.2% |
| 4856794 | 304.112.1.0 ↗ | a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain | 0.54 | 35.0 | 3.59e-01 | 83.1% | 67.5% |
| 4629438 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 42.0 | 3.74e-01 | 84.4% | 91.8% |
| 3635318 | 101.21.1.1 ↗ | alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › TP6A_N | 0.54 | 44.0 | 3.68e-01 | 89.6% | 60.0% |
| 5083453 | 304.139.1.3 ↗ | a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › Cas_Cas7 | 0.54 | 38.0 | 2.63e-01 | 75.3% | 78.7% |
| 4196358 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 42.0 | 3.70e-01 | 87.0% | 89.2% |
| 4396101 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 44.0 | 2.78e-01 | 90.9% | 51.6% |
| 4120121 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 41.0 | 3.66e-01 | 83.1% | 91.8% |
| 3940712 | 5.1.4.223 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RIC1_2nd | 0.53 | 42.0 | 2.42e-01 | 89.6% | 53.8% |
| 4586646 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 41.0 | 3.53e-01 | 85.7% | 84.8% |
| 4484391 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 42.0 | 3.62e-01 | 88.3% | 86.4% |
| 3912477 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.52 | 39.0 | 2.63e-01 | 80.5% | 34.7% |
| 4236774 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.52 | 40.0 | 3.41e-01 | 83.1% | 91.2% |
| 4354607 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.52 | 41.0 | 3.56e-01 | 85.7% | 89.2% |
| 4156749 | 3234.1.1.2 ↗ | a+b two layers › GerBC protein › GerBC protein › GerBC protein › Spore_GerAC, Spore_GerAC_N | 0.52 | 44.0 | 3.02e-01 | 96.1% | 67.7% |
| 4985264 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.52 | 41.0 | 3.44e-01 | 87.0% | 83.0% |
| 4133928 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.51 | 40.0 | 3.53e-01 | 87.0% | 90.8% |
| 4136078 | 3943.1.1.2 ↗ | beta sandwiches › Flagellar hook-associated protein 1 beta-sandwich domains › Flagellar hook-associated protein 1 beta-sandwich domains › Flagellar hook-associated protein 1 beta-sandwich domains › FliD_C | 0.50 | 37.0 | 3.57e-01 | 77.9% | 91.1% |