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polyprotein

Euk-Vir

Alternaria_arborescens_mitovirus_1

polyprotein__YP_009270635__Alternaria_arborescens_mitovirus_1__1826822

Identity

Accession:
YP_009270635 ↗
Protein ID:
polyprotein
Kingdom:
euk

Quality

72.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-112
PDB
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.70 53.0 3.81e-01 83.0% 28.6%
6ks6q01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.69 62.0 4.67e-01 100.0% 88.3%
1abvA00 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.59 48.0 4.94e-01 86.6% 98.1%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.58 47.0 4.93e-01 88.4% 99.0%
1bgpA01 1.10.520.10 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › 0.57 46.0 4.16e-01 90.2% 70.8%
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.56 29.0 3.22e-01 80.4% 60.7%
1m2vB01 1.20.120.730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain 0.56 46.0 4.02e-01 88.4% 59.2%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.56 32.0 3.44e-01 97.3% 65.2%
6b8hO01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.55 45.0 4.72e-01 92.9% 100.0%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 34.0 3.84e-01 74.1% 81.4%
5yixA00 1.10.601.10 Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor 0.52 40.0 2.98e-01 85.7% 68.5%
2xq0A03 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.51 41.0 3.66e-01 95.5% 61.1%
3h37A03 1.20.58.1960 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 39.0 3.74e-01 82.1% 89.1%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4960340 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.65 44.0 3.52e-01 85.7% 36.7%
5009983 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 49.0 4.24e-01 87.5% 82.2%
5032177 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.61 48.0 3.97e-01 85.7% 80.5%
3976873 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 44.0 3.47e-01 85.7% 38.6%
4964033 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 40.0 3.24e-01 83.9% 37.6%
3698007 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 42.0 3.36e-01 84.8% 39.5%
5057654 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.56 42.0 2.88e-01 77.7% 41.1%
4517631 2004.1.1.364 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.56 49.0 3.15e-01 97.3% 21.5%
5046440 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 42.0 3.46e-01 85.7% 45.0%
3196010 3930.1.1.15 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › DEAD, Helicase_C 0.54 48.0 3.14e-01 96.4% 24.2%
5022910 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 39.0 3.41e-01 75.9% 77.6%
3608820 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 41.0 3.33e-01 86.6% 43.7%
3399487 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.52 42.0 3.93e-01 84.8% 70.4%
4019039 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 42.0 3.30e-01 89.3% 43.1%
3289801 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 45.0 3.72e-01 99.1% 85.7%
3922622 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 41.0 3.26e-01 89.3% 64.2%
3391623 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 46.0 3.86e-01 100.0% 92.6%
3574876 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.50 42.0 3.97e-01 89.3% 74.1%
D2 medium residues 136-152_265-311_341-431
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 174.1 8.00e-51 61.3% 18.7%
PF05919.17 Mitovir_RNA_pol 59.8 3.70e-16 34.2% 9.5%
D3 medium residues 153-224_248-264
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1x5bA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 43.0 3.74e-01 74.2% 81.5%
1axdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 40.0 3.63e-01 74.2% 52.0%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 40.0 3.41e-01 73.0% 95.3%
1gwcA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 39.0 3.38e-01 76.4% 58.2%
3iq1B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 38.0 3.23e-01 75.3% 94.3%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 37.0 3.12e-01 73.0% 86.3%
3uarA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 38.0 3.66e-01 79.8% 82.2%
4ga6A02 1.20.970.50 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › 0.52 36.0 3.08e-01 73.0% 65.1%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 38.0 3.55e-01 79.8% 86.0%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 33.0 2.99e-01 70.8% 43.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3622868 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 35.0 3.11e-01 73.0% 44.3%
5073149 2488.1.1.1 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.52 32.0 2.42e-01 88.8% 23.0%
3785620 109.4.1.229 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SIL1 0.52 38.0 2.69e-01 77.5% 31.9%
4003485 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 36.0 3.15e-01 74.2% 54.1%
3393603 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 35.0 2.88e-01 73.0% 53.7%
D4 medium residues 225-247_312-340
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 26.3 5.20e-06 51.9% 4.6%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.61 40.0 3.46e-01 96.2% 40.4%
3gr0D01 3.30.70.1780 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 32.0 3.57e-01 100.0% 65.9%
1yj7B01 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.58 37.0 3.39e-01 100.0% 47.9%
2nscA01 3.30.70.1050 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trigger factor ribosome-binding domain 0.57 41.0 3.74e-01 82.7% 100.0%
4gdxB00 3.60.20.40 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit 0.56 43.0 3.02e-01 90.4% 51.3%
2wdoA00 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.54 40.0 3.12e-01 80.8% 69.9%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.52 38.0 2.47e-01 80.8% 92.0%
6ketA01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.52 38.0 2.40e-01 86.5% 22.6%
1h0hA02 3.40.50.740 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 41.0 2.77e-01 96.2% 83.3%
3icyA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.51 40.0 3.26e-01 96.2% 49.2%
1uw4A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.50 41.0 3.53e-01 98.1% 81.3%
3rlfF03 2.40.430.10 Mainly Beta › Beta Barrel › Periplasmic binding protein-like II › D-maltodextrin-binding protein, MBP 0.50 42.0 3.67e-01 100.0% 79.5%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.50 37.0 2.55e-01 86.5% 82.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3853273 327.11.2.27 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_Vigilin 0.57 35.0 3.61e-01 100.0% 62.0%
4890630 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 48.0 3.17e-01 100.0% 45.6%
3550019 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.56 41.0 2.28e-01 84.6% 41.8%
3508428 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 45.0 3.10e-01 90.4% 27.8%
3444901 4954.1.1.0 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit 0.55 41.0 2.92e-01 100.0% 25.1%
5004463 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 40.0 2.54e-01 80.8% 56.9%
4043003 601.7.1.6 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase 0.55 44.0 3.25e-01 100.0% 45.9%
5083025 301.4.1.1 a+b three layers › Bacillus chorismate mutase-like › Holliday junction resolvase RusA › Holliday junction resolvase RusA › RusA 0.54 39.0 3.05e-01 80.8% 76.8%
4951717 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.52 37.0 3.41e-01 78.8% 72.0%
4670273 868.1.1.8 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › SLS1_C 0.52 42.0 2.82e-01 96.2% 66.7%
3871096 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 41.0 2.59e-01 90.4% 71.9%
4983222 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.50 40.0 2.54e-01 100.0% 83.1%
4098243 7512.1.1.6 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 0.50 41.0 2.74e-01 100.0% 20.8%
D5 medium residues 432-527
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05919.17 best Mitovir_RNA_pol 35.8 7.10e-09 100.0% 19.1%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 43.0 4.11e-01 77.1% 89.7%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.58 44.0 4.30e-01 81.2% 94.2%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.56 40.0 3.70e-01 76.0% 68.2%
4n1yB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 44.0 3.45e-01 91.7% 87.2%
3rr1A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.54 35.0 3.17e-01 82.3% 45.3%
2n1rA00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.54 41.0 3.70e-01 93.8% 59.0%
1jr8A00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.53 36.0 3.53e-01 72.9% 62.9%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 42.0 3.69e-01 91.7% 57.6%
2vvwA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.53 42.0 3.69e-01 88.5% 56.0%
8hdlA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 43.0 3.29e-01 94.8% 54.4%
1oshA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 43.0 3.42e-01 96.9% 88.4%
3feyA02 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 44.0 3.59e-01 100.0% 80.2%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.50 40.0 3.72e-01 86.5% 82.8%
2rfqB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.50 40.0 3.93e-01 89.6% 84.4%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3632779 145.1.1.0 alpha arrays › F-box domain › F-box domain › F-box domain 0.72 54.0 4.90e-01 80.2% 65.4%
3536798 633.24.1.4 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › RIN1 0.63 45.0 4.52e-01 75.0% 83.0%
3807400 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 39.0 3.69e-01 72.9% 93.9%
3738170 616.1.1.1 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 0.55 44.0 3.94e-01 87.5% 75.0%
4133754 186.1.1.1 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.55 41.0 3.90e-01 85.4% 66.1%
1144652 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.54 44.0 3.45e-01 91.7% 87.2%
4362692 186.1.1.1 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.54 39.0 3.92e-01 83.3% 73.0%
3410368 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 47.0 2.78e-01 95.8% 17.2%
4946658 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.53 41.0 3.60e-01 82.3% 61.4%
3697926 601.21.1.1 alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr 0.53 37.0 3.14e-01 72.9% 82.9%
3861079 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 42.0 3.30e-01 93.8% 77.0%
3876247 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.50 37.0 3.45e-01 77.1% 90.0%
D6 medium residues 559-709
PDB