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pre1_saliva_scaffold_4_prodigal-single.1__X__X__00178
Bact-Virpre1_saliva_scaffold_4_prodigal-single.1__X__X__00178
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 107-126_165-289_361-371
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1krlA00 | 6.20.50.130 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.61 | 19.0 | 3.37e-01 | 78.8% | 90.9% |
| 2retA00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.53 | 26.0 | 3.43e-01 | 76.9% | 85.7% |
| 1e50B00 | 2.40.250.10 | Mainly Beta › Beta Barrel › Polyomavirus Enhancer Binding Protein 2; Chain: A; › Core binding factor, beta subunit | 0.51 | 24.0 | 2.60e-01 | 81.4% | 48.5% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5060660 | 3629.1.1.0 ↗ | beta sandwiches › Tail sheath protein beta-sandwich domain › Tail sheath protein beta-sandwich domain › Tail sheath protein beta-sandwich domain | 0.65 | 46.0 | 5.23e-01 | 100.0% | 94.2% |
| 3245973 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.52 | 38.0 | 2.73e-01 | 75.0% | 91.1% |
D2
high
residues 623-688
Domain cluster:
rep: IMGVR_UViG_3300010327_000704-3300010327-Ga0116246_1000102125__D309-398
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lmlA01 | 3.10.450.690 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.73 | 65.0 | 5.34e-01 | 100.0% | 56.2% |
| 3hxlA05 | 3.30.360.90 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › | 0.73 | 65.0 | 6.40e-01 | 100.0% | 95.7% |
| 4htgA03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.69 | 55.0 | 5.21e-01 | 93.9% | 74.7% |
| 2qkdA01 | 2.20.25.420 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain | 0.68 | 46.0 | 5.28e-01 | 72.7% | 97.9% |
| 1ni9A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.68 | 59.0 | 4.57e-01 | 100.0% | 57.6% |
| 2ia7A00 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.67 | 57.0 | 4.91e-01 | 100.0% | 58.6% |
| 3ef8A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.66 | 57.0 | 4.45e-01 | 98.5% | 70.3% |
| 3uoaB02 | 2.60.40.3360 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.65 | 57.0 | 4.53e-01 | 100.0% | 87.5% |
| 5dstA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.64 | 51.0 | 3.74e-01 | 87.9% | 98.9% |
| 1b78A00 | 3.90.950.10 | Alpha Beta › Alpha-Beta Complex › Maf protein › | 0.64 | 49.0 | 3.61e-01 | 84.8% | 64.1% |
| 3b7cA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.63 | 53.0 | 4.45e-01 | 97.0% | 85.0% |
| 3butA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.63 | 51.0 | 4.13e-01 | 89.4% | 82.4% |
| 1y8cA02 | 2.20.25.110 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases | 0.62 | 49.0 | 5.08e-01 | 100.0% | 93.3% |
| 2ddmB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.61 | 44.0 | 2.90e-01 | 77.3% | 44.6% |
| 1wpuA00 | 3.40.1510.10 | Alpha Beta › 3-Layer(aba) Sandwich › Hut operon positive regulatory protein HutP › Hut operon regulatory protein HutP | 0.61 | 52.0 | 4.01e-01 | 95.5% | 80.3% |
| 4ydzA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.60 | 43.0 | 3.43e-01 | 77.3% | 55.6% |
| 4inaA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.59 | 45.0 | 3.32e-01 | 84.8% | 94.9% |
| 1tuhA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.59 | 49.0 | 4.07e-01 | 100.0% | 80.9% |
| 4cvuA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 46.0 | 3.88e-01 | 86.4% | 83.6% |
| 2amhA00 | 3.90.950.10 | Alpha Beta › Alpha-Beta Complex › Maf protein › | 0.58 | 48.0 | 3.44e-01 | 90.9% | 60.5% |
| 2giaB00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.58 | 42.0 | 3.29e-01 | 92.4% | 35.6% |
| 2b39A03 | 2.60.40.1940 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.57 | 49.0 | 4.05e-01 | 100.0% | 82.4% |
| 5ftzA00 | 2.70.50.50 | Mainly Beta › Distorted Sandwich › Coagulation Factor XIII; Chain A, domain 1 › chitin-binding protein cbp21 | 0.57 | 49.0 | 3.70e-01 | 100.0% | 56.4% |
| 2i9wA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 48.0 | 3.63e-01 | 100.0% | 47.7% |
| 3r0qA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.56 | 46.0 | 3.36e-01 | 95.5% | 98.1% |
| 2pn5A03 | 2.60.40.1940 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.56 | 49.0 | 4.24e-01 | 100.0% | 82.9% |
| 1g4wR02 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.56 | 44.0 | 3.13e-01 | 92.4% | 26.2% |
| 4iykA02 | 2.60.40.2060 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.56 | 47.0 | 4.02e-01 | 100.0% | 90.7% |
| 2krtA01 | 3.10.450.270 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 47.0 | 4.15e-01 | 100.0% | 68.9% |
| 3abiA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.55 | 47.0 | 3.53e-01 | 100.0% | 78.0% |
| 2covG00 | 2.60.40.2450 | Mainly Beta › Sandwich › Immunoglobulin-like › Beta-1,3-xylanase, CBM31 domain | 0.54 | 48.0 | 4.36e-01 | 100.0% | 81.8% |
| 2gtlN02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.54 | 46.0 | 3.53e-01 | 100.0% | 51.8% |
| 3mnmA00 | 2.60.40.1230 | Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain | 0.54 | 46.0 | 3.97e-01 | 100.0% | 79.5% |
| 1j7dA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.54 | 42.0 | 3.40e-01 | 89.4% | 80.0% |
| 2wllA02 | 2.60.40.1400 | Mainly Beta › Sandwich › Immunoglobulin-like › G protein-activated inward rectifier potassium channel 1 | 0.53 | 47.0 | 3.66e-01 | 100.0% | 73.1% |
| 1iz6A01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.53 | 40.0 | 4.01e-01 | 86.4% | 79.7% |
| 1y7uA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.52 | 45.0 | 3.41e-01 | 97.0% | 65.9% |
| 1gyvA00 | 2.60.40.1230 | Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain | 0.52 | 43.0 | 3.60e-01 | 95.5% | 67.5% |
| 4depC02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 45.0 | 3.96e-01 | 100.0% | 79.4% |
| 1uv4A00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.52 | 44.0 | 2.94e-01 | 100.0% | 30.2% |
| 3pv7A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 39.0 | 3.60e-01 | 86.4% | 90.4% |
| 5xzqF00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 40.0 | 3.56e-01 | 89.4% | 86.4% |
| 8evkA01 | 3.30.1130.10 | Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain | 0.51 | 43.0 | 3.68e-01 | 95.5% | 97.2% |
| 4r6uA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 42.0 | 3.91e-01 | 100.0% | 76.1% |
| 7cymA04 | 2.60.40.60 | Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins | 0.50 | 41.0 | 3.79e-01 | 100.0% | 90.7% |
| 5aa7A00 | 2.70.50.50 | Mainly Beta › Distorted Sandwich › Coagulation Factor XIII; Chain A, domain 1 › chitin-binding protein cbp21 | 0.50 | 42.0 | 3.41e-01 | 100.0% | 53.5% |
| 1zxqA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 43.0 | 4.03e-01 | 100.0% | 80.0% |
| 1luiA00 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.50 | 42.0 | 3.64e-01 | 97.0% | 58.3% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3173251 | 4051.1.1.1 ↗ | a+b two layers › a+b domain in Capz › a+b domain in Capz › a+b domain in Capz › F_actin_cap_B | 0.76 | 66.0 | 4.86e-01 | 95.5% | 40.6% |
| 3183463 | 241.15.1.3 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 | 0.75 | 66.0 | 5.59e-01 | 100.0% | 68.2% |
| 4416182 | 241.15.1.3 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 | 0.74 | 66.0 | 5.62e-01 | 98.5% | 64.8% |
| 3513463 | 283.2.1.10 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › PF29514 | 0.72 | 63.0 | 5.07e-01 | 100.0% | 75.4% |
| 5011932 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.71 | 61.0 | 5.20e-01 | 95.5% | 64.8% |
| 5004672 | 283.2.1.1 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 | 0.71 | 60.0 | 4.97e-01 | 100.0% | 53.3% |
| 3977327 | 283.2.1.1 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 | 0.70 | 61.0 | 4.73e-01 | 100.0% | 47.0% |
| 4961528 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.70 | 44.0 | 3.75e-01 | 71.2% | 40.0% |
| 4825040 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.69 | 48.0 | 3.75e-01 | 95.5% | 33.8% |
| 4986581 | 283.1.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase | 0.69 | 59.0 | 5.42e-01 | 100.0% | 77.8% |
| 4970559 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.68 | 57.0 | 5.04e-01 | 97.0% | 67.0% |
| 3659467 | 243.1.1.45 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › S6PP_C | 0.67 | 59.0 | 4.77e-01 | 98.5% | 85.6% |
| 5025341 | 330.2.1.0 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) | 0.67 | 57.0 | 5.01e-01 | 97.0% | 65.0% |
| 4960250 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.67 | 57.0 | 4.97e-01 | 95.5% | 65.0% |
| 3499841 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.66 | 49.0 | 4.47e-01 | 81.8% | 58.9% |
| 4983377 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.66 | 55.0 | 4.74e-01 | 98.5% | 58.1% |
| 3819309 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.66 | 49.0 | 4.57e-01 | 81.8% | 65.9% |
| 5075859 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.66 | 56.0 | 4.77e-01 | 97.0% | 59.1% |
| 3596304 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.66 | 54.0 | 5.13e-01 | 97.0% | 77.5% |
| 3281635 | 330.2.1.1 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE | 0.65 | 55.0 | 4.68e-01 | 95.5% | 58.2% |
| 3587662 | 330.18.1.0 ↗ | a+b two layers › dsRBD-like › Anti-CRISPR protein AcrIIA6 › Anti-CRISPR protein AcrIIA6 | 0.65 | 42.0 | 3.81e-01 | 74.2% | 48.9% |
| 3879303 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.64 | 46.0 | 4.32e-01 | 78.8% | 62.5% |
| 3937984 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.64 | 46.0 | 4.08e-01 | 77.3% | 52.0% |
| 3481504 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.64 | 53.0 | 4.43e-01 | 97.0% | 52.5% |
| 4634682 | 330.6.1.1 ↗ | a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer | 0.63 | 50.0 | 4.05e-01 | 87.9% | 64.6% |
| 5045089 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.63 | 54.0 | 4.70e-01 | 95.5% | 68.0% |
| 3824181 | 375.1.1.21 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 | 0.63 | 51.0 | 5.28e-01 | 95.5% | 96.7% |
| 3446425 | 11.1.1.558 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF6598 | 0.62 | 54.0 | 4.49e-01 | 100.0% | 69.2% |
| 4205167 | 330.6.1.1 ↗ | a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer | 0.62 | 49.0 | 3.81e-01 | 86.4% | 92.4% |
| 3453703 | 316.1.1.24 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm | 0.61 | 53.0 | 3.83e-01 | 100.0% | 54.3% |
| 4672222 | 4010.1.1.3 ↗ | a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 | 0.60 | 51.0 | 3.48e-01 | 100.0% | 31.5% |
| 3603359 | 4.1.1.459 ↗ | beta barrels › SH3 › SH3 › SH3 › PF29994 | 0.60 | 51.0 | 4.45e-01 | 100.0% | 81.8% |
| 3345244 | 5.1.8.7 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › putative conserved lipoprotein NT01CX_1156 › FBA_1 | 0.60 | 52.0 | 4.08e-01 | 98.5% | 54.5% |
| 5018204 | 7520.1.1.0 ↗ | a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like | 0.60 | 49.0 | 3.64e-01 | 89.4% | 68.5% |
| 3611338 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.60 | 50.0 | 4.19e-01 | 98.5% | 57.6% |
| 4933928 | 11.1.5.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f | 0.60 | 52.0 | 4.61e-01 | 100.0% | 87.9% |
| 4878713 | 331.3.1.42 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Mtb12_C | 0.60 | 52.0 | 4.58e-01 | 100.0% | 89.1% |
| 3788749 | 6109.1.1.0 ↗ | a+b two layers › N-terminal domain of chitin biosynthesis protein CHS6 › N-terminal domain of chitin biosynthesis protein CHS6 › N-terminal domain of chitin biosynthesis protein CHS6 | 0.60 | 53.0 | 4.06e-01 | 100.0% | 59.3% |
| 4956239 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 52.0 | 4.50e-01 | 100.0% | 84.8% |
| 5033005 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 50.0 | 4.00e-01 | 97.0% | 79.9% |
| 4568161 | 283.2.1.18 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Lipoprotein_17 | 0.59 | 46.0 | 4.43e-01 | 100.0% | 73.8% |
| 3193851 | 3561.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Med17 | 0.59 | 51.0 | 3.10e-01 | 100.0% | 16.0% |
| 3463743 | 298.1.1.15 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Sacchrp_dh_C | 0.59 | 50.0 | 3.36e-01 | 100.0% | 96.5% |
| 3788033 | 4099.1.1.10 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med1 | 0.59 | 51.0 | 3.95e-01 | 100.0% | 71.2% |
| 4938275 | 11.1.1.138 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › NPCBM_assoc | 0.58 | 50.0 | 4.27e-01 | 100.0% | 87.8% |
| 3569641 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.58 | 50.0 | 4.47e-01 | 100.0% | 89.5% |
| 3701914 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.58 | 48.0 | 4.30e-01 | 95.5% | 66.3% |
| 3852952 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.57 | 40.0 | 3.88e-01 | 78.8% | 63.7% |
| 3865594 | 11.1.1.640 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N | 0.57 | 49.0 | 4.23e-01 | 100.0% | 77.3% |
| 3923711 | 220.1.1.66 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH | 0.57 | 46.0 | 3.37e-01 | 87.9% | 64.0% |
| 3576152 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.57 | 48.0 | 3.15e-01 | 97.0% | 22.0% |
| 3269706 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 37.0 | 3.53e-01 | 71.2% | 55.0% |
| 3171913 | 11.1.1.44 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Alpha_adaptinC2 | 0.57 | 48.0 | 4.18e-01 | 100.0% | 80.0% |
| 4116159 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.57 | 42.0 | 3.87e-01 | 83.3% | 60.0% |
| 334108 | 71.1.1.9 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › VioE | 0.57 | 43.0 | 3.25e-01 | 97.0% | 30.6% |
| 3232364 | 3335.1.1.0 ↗ | beta barrels › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B | 0.57 | 43.0 | 4.39e-01 | 84.8% | 95.4% |
| 3691753 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.56 | 47.0 | 3.59e-01 | 100.0% | 88.9% |
| 4966673 | 11.1.1.51 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LEA_2 | 0.56 | 48.0 | 4.21e-01 | 100.0% | 92.4% |
| 4989417 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.56 | 48.0 | 3.77e-01 | 95.5% | 88.6% |
| 4992813 | 11.1.1.103 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CARDB | 0.56 | 48.0 | 4.15e-01 | 100.0% | 87.3% |
| 3622620 | 11.1.1.959 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ILCR1_N | 0.55 | 47.0 | 3.60e-01 | 100.0% | 61.8% |
| 5062045 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 47.0 | 4.05e-01 | 100.0% | 82.7% |
| 5053700 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 46.0 | 3.46e-01 | 95.5% | 92.4% |
| 3635086 | 868.1.1.8 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › SLS1_C | 0.54 | 42.0 | 2.76e-01 | 86.4% | 33.2% |
| 3460917 | 11.10.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like | 0.54 | 44.0 | 3.88e-01 | 100.0% | 59.0% |
| 4944246 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 45.0 | 4.02e-01 | 100.0% | 86.7% |
| 4978574 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.54 | 46.0 | 3.49e-01 | 97.0% | 92.7% |
| 3430448 | 10.1.1.11 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_16 | 0.54 | 42.0 | 3.47e-01 | 100.0% | 45.4% |
| 5037572 | 4178.1.1.1 ↗ | beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › DUF5110 | 0.53 | 45.0 | 3.68e-01 | 93.9% | 95.2% |
| 5064888 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 47.0 | 3.67e-01 | 100.0% | 67.1% |
| 5048343 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 46.0 | 3.69e-01 | 100.0% | 63.7% |
| 4375025 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 47.0 | 3.60e-01 | 100.0% | 61.3% |
| 5033710 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 46.0 | 3.98e-01 | 100.0% | 87.6% |
| 5075519 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.52 | 46.0 | 3.43e-01 | 100.0% | 52.6% |
| 3923456 | 2484.1.1.4 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H | 0.52 | 47.0 | 3.47e-01 | 100.0% | 77.6% |
| 5076766 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.51 | 37.0 | 3.41e-01 | 80.3% | 58.9% |
| 3547472 | 243.3.1.4 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Latexin_N | 0.51 | 41.0 | 3.71e-01 | 98.5% | 70.5% |
| 5045594 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.51 | 42.0 | 3.73e-01 | 98.5% | 73.3% |
D3
medium
residues 24-91
Domain cluster:
representative
D4
medium
residues 290-360
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2uxwA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 64.0 | 4.73e-01 | 100.0% | 49.5% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 62.0 | 4.81e-01 | 100.0% | 58.7% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 56.0 | 4.67e-01 | 100.0% | 61.8% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.62 | 54.0 | 4.21e-01 | 100.0% | 73.6% |
| 2kseA00 | 1.20.5.1040 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Sensor protein qsec. | 0.58 | 44.0 | 4.34e-01 | 83.1% | 98.7% |
| 7cosB02 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.55 | 45.0 | 4.40e-01 | 91.5% | 100.0% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4364663 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.69 | 57.0 | 4.97e-01 | 100.0% | 59.1% |
| 3196270 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 60.0 | 5.15e-01 | 100.0% | 82.6% |
| 3801982 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.66 | 57.0 | 5.25e-01 | 98.6% | 89.5% |
| 3903423 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.63 | 54.0 | 4.82e-01 | 97.2% | 70.5% |
| 5032064 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.63 | 45.0 | 4.36e-01 | 77.5% | 68.4% |
| 4008954 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.61 | 52.0 | 4.74e-01 | 100.0% | 70.0% |
| 3615716 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.58 | 49.0 | 4.14e-01 | 97.2% | 55.8% |
| 3640808 | 632.7.1.52 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › Sds3 | 0.52 | 37.0 | 3.42e-01 | 85.9% | 58.9% |
D5
medium
residues 399-477_610-622
Domain cluster:
representative
CATH (59)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5irnA02 | 3.80.10.10 | Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor | 0.63 | 44.0 | 4.47e-01 | 73.9% | 96.8% |
| 2h3hB02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.61 | 44.0 | 3.72e-01 | 76.1% | 61.8% |
| 4n03A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.61 | 44.0 | 3.53e-01 | 75.0% | 54.0% |
| 4ry8C02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 44.0 | 3.63e-01 | 76.1% | 62.7% |
| 4k17B03 | 3.80.10.10 | Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor | 0.60 | 44.0 | 2.78e-01 | 77.2% | 25.3% |
| 3lkbA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 43.0 | 3.56e-01 | 75.0% | 73.1% |
| 7sf2A03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.60 | 45.0 | 3.15e-01 | 79.3% | 87.7% |
| 6khnA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.59 | 44.0 | 3.18e-01 | 79.3% | 28.5% |
| 5irlA02 | 3.80.10.10 | Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor | 0.59 | 42.0 | 2.95e-01 | 75.0% | 37.1% |
| 1tjyA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 43.0 | 3.61e-01 | 76.1% | 57.5% |
| 1usgA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 42.0 | 3.62e-01 | 75.0% | 59.7% |
| 3vaxA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.58 | 43.0 | 3.13e-01 | 78.3% | 49.0% |
| 5bqpD00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 38.0 | 3.11e-01 | 71.7% | 34.7% |
| 1iirA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.58 | 43.0 | 3.31e-01 | 79.3% | 35.3% |
| 2vzoA03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.58 | 42.0 | 2.89e-01 | 77.2% | 24.8% |
| 1qz9A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.58 | 43.0 | 3.10e-01 | 78.3% | 51.7% |
| 6gt9A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 41.0 | 3.40e-01 | 76.1% | 64.9% |
| 4ritA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 42.0 | 3.17e-01 | 78.3% | 31.8% |
| 3f67A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.57 | 42.0 | 3.14e-01 | 78.3% | 42.1% |
| 2jisB02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 41.0 | 3.10e-01 | 78.3% | 30.2% |
| 2ejbA00 | 3.40.50.1950 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like | 0.57 | 41.0 | 3.36e-01 | 77.2% | 67.6% |
| 3td9A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 41.0 | 3.48e-01 | 76.1% | 57.0% |
| 3caiA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 41.0 | 3.05e-01 | 79.3% | 49.0% |
| 6a6eA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 41.0 | 3.03e-01 | 79.3% | 49.4% |
| 2o1sA02 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.55 | 38.0 | 3.10e-01 | 70.7% | 78.5% |
| 4m8kA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.55 | 40.0 | 3.12e-01 | 78.3% | 45.1% |
| 4ernA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 39.0 | 2.98e-01 | 75.0% | 90.8% |
| 4ifeA02 | 3.30.420.240 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.55 | 37.0 | 2.86e-01 | 70.7% | 35.7% |
| 8kcaB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 39.0 | 3.22e-01 | 75.0% | 61.4% |
| 4ms4B02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 39.0 | 3.22e-01 | 76.1% | 68.9% |
| 4q6bA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 39.0 | 3.51e-01 | 76.1% | 64.2% |
| 1w36B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 39.0 | 2.93e-01 | 77.2% | 32.3% |
| 1jr2A01 | 3.40.50.10090 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 38.0 | 3.54e-01 | 75.0% | 73.3% |
| 3ugvA02 | 3.20.20.120 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain | 0.54 | 37.0 | 2.81e-01 | 71.7% | 28.0% |
| 3kloA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 38.0 | 3.34e-01 | 75.0% | 58.3% |
| 3dmyA02 | 3.40.50.261 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains | 0.53 | 41.0 | 3.64e-01 | 84.8% | 67.9% |
| 4jd2B01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 38.0 | 3.13e-01 | 75.0% | 62.5% |
| 5x7fA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 38.0 | 2.97e-01 | 75.0% | 44.9% |
| 2aeaA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.53 | 40.0 | 2.95e-01 | 80.4% | 38.9% |
| 2e4uA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 38.0 | 3.16e-01 | 76.1% | 72.8% |
| 1z05A03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 37.0 | 3.15e-01 | 76.1% | 56.5% |
| 5fbhA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.52 | 38.0 | 3.08e-01 | 76.1% | 69.0% |
| 6b4kB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 33.0 | 2.76e-01 | 70.7% | 34.1% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 37.0 | 2.97e-01 | 76.1% | 60.8% |
| 6imeA01 | 3.40.1180.10 | Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like | 0.52 | 39.0 | 2.84e-01 | 79.3% | 30.5% |
| 1a97B00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 38.0 | 3.25e-01 | 76.1% | 48.6% |
| 3weeA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 37.0 | 3.03e-01 | 76.1% | 63.9% |
| 1hv8A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 37.0 | 3.21e-01 | 76.1% | 70.2% |
| 7tlrA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.52 | 38.0 | 2.80e-01 | 78.3% | 43.3% |
| 3f3kA00 | 3.40.50.1240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like | 0.51 | 38.0 | 2.81e-01 | 79.3% | 72.3% |
| 3mweB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 36.0 | 3.21e-01 | 75.0% | 75.4% |
| 2rbgA00 | 3.40.50.11100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 36.0 | 3.33e-01 | 75.0% | 68.5% |
| 1f7uA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.51 | 37.0 | 2.63e-01 | 80.4% | 66.6% |
| 4bgdA08 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 35.0 | 2.77e-01 | 71.7% | 68.5% |
| 1m0wA04 | 3.40.50.1760 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glutathione synthase, substrate-binding domain superfamily, eukaryotic | 0.50 | 36.0 | 3.25e-01 | 75.0% | 76.0% |
| 3rotA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.50 | 36.0 | 3.20e-01 | 75.0% | 56.2% |
| 7kl6A01 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 35.0 | 3.12e-01 | 73.9% | 59.7% |
| 3etcA01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.50 | 37.0 | 2.44e-01 | 79.3% | 65.0% |
| 8alzB06 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 37.0 | 2.99e-01 | 80.4% | 49.2% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4933399 | 2007.1.14.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like | 0.63 | 43.0 | 3.86e-01 | 72.8% | 51.2% |
| 3601539 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.62 | 47.0 | 3.58e-01 | 81.5% | 50.9% |
| 3251898 | 7590.1.1.0 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs | 0.62 | 44.0 | 4.12e-01 | 73.9% | 60.9% |
| 3258359 | 207.1.1.22 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 | 0.61 | 45.0 | 3.09e-01 | 79.3% | 47.9% |
| 3887203 | 207.1.1.47 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1,LRR_6 | 0.60 | 43.0 | 2.79e-01 | 76.1% | 26.6% |
| 5026686 | 2484.1.1.333 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1464 | 0.60 | 41.0 | 3.29e-01 | 71.7% | 36.8% |
| 3364912 | 3016.1.1.4 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Pyridoxal_deC | 0.60 | 44.0 | 2.80e-01 | 78.3% | 16.3% |
| 3327275 | 7579.1.1.51 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF676 | 0.59 | 43.0 | 3.00e-01 | 78.3% | 62.8% |
| 3954525 | 7592.1.1.4 ↗ | a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Cas_Csm6_CARF | 0.59 | 41.0 | 3.41e-01 | 71.7% | 41.2% |
| 3399733 | 7577.1.1.4 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Pyridoxal_deC | 0.59 | 43.0 | 2.92e-01 | 78.3% | 20.0% |
| 4411884 | 7577.1.1.3 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 | 0.59 | 44.0 | 2.96e-01 | 78.3% | 39.7% |
| 4135745 | 7577.1.1.4 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Pyridoxal_deC | 0.59 | 43.0 | 2.77e-01 | 79.3% | 15.8% |
| 3704977 | 207.1.1.22 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 | 0.59 | 43.0 | 2.87e-01 | 76.1% | 32.1% |
| 4024269 | 7512.1.1.54 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 | 0.59 | 44.0 | 3.63e-01 | 80.4% | 57.1% |
| 3962110 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.59 | 44.0 | 3.07e-01 | 81.5% | 55.1% |
| None | — | 0.58 | 44.0 | 3.09e-01 | 81.5% | 78.4% | |
| None | — | 0.58 | 43.0 | 2.86e-01 | 79.3% | 18.8% | |
| 3929375 | 2496.1.1.0 ↗ | a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like | 0.58 | 42.0 | 3.83e-01 | 78.3% | 61.5% |
| 3530704 | 207.1.1.22 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 | 0.58 | 45.0 | 3.01e-01 | 84.8% | 25.6% |
| 4056202 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.58 | 41.0 | 3.17e-01 | 73.9% | 42.0% |
| None | — | 0.57 | 42.0 | 2.76e-01 | 78.3% | 17.4% | |
| 5042343 | 2003.1.6.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Tubulin | 0.57 | 42.0 | 3.32e-01 | 77.2% | 60.5% |
| 5049384 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.56 | 39.0 | 2.93e-01 | 73.9% | 58.1% |
| 102676 | 2004.1.1.49 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase | 0.56 | 43.0 | 2.81e-01 | 84.8% | 62.0% |
| 3279475 | 7567.1.1.1 ↗ | a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like › PIG-L | 0.56 | 40.0 | 3.11e-01 | 77.2% | 32.6% |
| 3595246 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.55 | 41.0 | 3.47e-01 | 78.3% | 51.0% |
| 5050225 | 2004.1.1.211 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P | 0.55 | 39.0 | 3.08e-01 | 75.0% | 96.2% |
| 3542657 | 2007.1.2.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor | 0.55 | 40.0 | 3.21e-01 | 77.2% | 68.9% |
| 3303891 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.55 | 43.0 | 2.99e-01 | 84.8% | 52.3% |
| 4449595 | 2004.1.1.455 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 | 0.55 | 41.0 | 2.50e-01 | 81.5% | 64.2% |
| 3289799 | 7581.1.1.12 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › ACP_syn_III_C | 0.54 | 38.0 | 3.25e-01 | 72.8% | 60.0% |
| 4024832 | 2003.1.1.82 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Slo-like_RCK | 0.54 | 40.0 | 2.68e-01 | 81.5% | 27.5% |
| 4198335 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.54 | 39.0 | 3.66e-01 | 78.3% | 85.8% |
| 3630231 | 7590.1.1.3 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi,ArgoMid | 0.53 | 40.0 | 3.11e-01 | 79.3% | 56.5% |
| 3506347 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.53 | 35.0 | 2.95e-01 | 70.7% | 38.2% |
| 1789440 | 2484.1.1.61 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PilM_2 | 0.53 | 38.0 | 3.10e-01 | 75.0% | 80.4% |
| 3950240 | 2004.1.1.49 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase | 0.52 | 39.0 | 2.88e-01 | 82.6% | 50.7% |
| 4087557 | 7581.1.1.1 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N | 0.52 | 37.0 | 2.67e-01 | 75.0% | 38.6% |
| 1879220 | 7577.1.1.3 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 | 0.51 | 38.0 | 2.64e-01 | 79.3% | 39.4% |
| 3562712 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.51 | 38.0 | 3.03e-01 | 80.4% | 53.0% |
| 3270921 | 261.1.1.1 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT | 0.51 | 36.0 | 2.43e-01 | 75.0% | 51.8% |
D6
medium
residues 478-609
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4h5bA00 | 3.30.1460.70 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.50 | 32.0 | 3.08e-01 | 84.1% | 54.6% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4995822 | 2499.2.1.1 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 | 0.83 | 67.0 | 5.25e-01 | 91.7% | 43.5% |
| 4882286 | 2499.2.1.1 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 | 0.81 | 60.0 | 5.77e-01 | 91.7% | 67.5% |
| 4888782 | 2499.2.1.2 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1,Gp18_domIII_N | 0.80 | 76.0 | 5.76e-01 | 100.0% | 48.2% |
| 5004680 | 2499.2.1.1 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 | 0.79 | 61.0 | 4.71e-01 | 91.7% | 38.5% |
| 2468538 | 2499.2.1.0 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 | 0.75 | 58.0 | 4.55e-01 | 91.7% | 41.2% |
| 3978226 | 2499.2.1.1 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 | 0.74 | 62.0 | 4.73e-01 | 91.7% | 41.1% |
| 1518917 | 2499.2.1.2 ↗ | a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1,Gp18_domIII_N | 0.73 | 58.0 | 4.50e-01 | 91.7% | 40.3% |
| 3164915 | 3019.1.1.11 ↗ | beta sandwiches › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › Phage_sheath_1 | 0.71 | 52.0 | 4.29e-01 | 92.4% | 44.0% |
| 3704645 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.53 | 30.0 | 3.46e-01 | 88.6% | 78.9% |
| 3956773 | 4267.1.1.1 ↗ | a+b duplicates or obligate multimers › YefM-like › YefM-like › YefM-like › PhdYeFM_antitox | 0.52 | 21.0 | 2.57e-01 | 77.3% | 55.0% |
| 4559971 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.52 | 27.0 | 3.38e-01 | 81.8% | 85.3% |
| 4057167 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.51 | 27.0 | 3.31e-01 | 76.5% | 87.7% |