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pre3_saliva_scaffold_3_prodigal-single.1__X__X__00027

Bact-Vir

pre3_saliva_scaffold_3_prodigal-single.1__X__X__00027

Identity

Kingdom:
phage

Quality

85.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-52
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1w9cA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.83 62.0 3.73e-01 78.8% 16.8%
1whuA00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.83 65.0 5.10e-01 84.6% 46.2%
2e6oA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.82 62.0 5.15e-01 80.8% 50.6%
1n5uA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.81 60.0 4.73e-01 78.8% 41.7%
1wgfA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.80 58.0 5.82e-01 78.8% 75.5%
4ixjA01 3.30.1300.80 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.79 60.0 5.17e-01 80.8% 59.7%
1j78A05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.79 56.0 5.41e-01 76.9% 71.7%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.77 60.0 4.31e-01 84.6% 46.2%
1nrwA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.76 55.0 4.08e-01 78.8% 30.8%
5cbgA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 62.0 4.91e-01 88.5% 78.4%
1cm0A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.75 56.0 3.96e-01 82.7% 37.0%
4evxA00 1.10.1740.240 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.75 61.0 5.00e-01 92.3% 85.6%
1dj8A00 1.10.890.10 Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › HNS-dependent expression A 0.74 56.0 4.90e-01 82.7% 57.0%
3ermB00 1.10.10.710 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like 0.74 57.0 5.34e-01 82.7% 67.2%
153lA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.73 58.0 4.01e-01 90.4% 71.9%
1kxpD03 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.73 52.0 4.39e-01 76.9% 46.6%
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 62.0 4.50e-01 98.1% 59.7%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 54.0 5.26e-01 82.7% 82.8%
3v7nA01 3.90.1380.10 Alpha Beta › Alpha-Beta Complex › threonine synthase, domain 1, chain A › Threonine synthase, N-terminal domain 0.70 51.0 4.23e-01 78.8% 45.3%
5mmiJ02 1.10.10.250 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain 0.70 50.0 4.62e-01 80.8% 58.0%
4v19K02 1.10.10.250 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain 0.70 50.0 4.53e-01 78.8% 58.7%
1kl7A02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 49.0 3.10e-01 75.0% 15.1%
3au4A01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.69 47.0 3.22e-01 73.1% 42.3%
1fcqA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.69 54.0 3.40e-01 92.3% 21.3%
3c24A02 1.10.3640.10 Mainly Alpha › Orthogonal Bundle › putative oxidoreductase fold › Semialdehyde dehydrogenase-like, C-terminal 0.67 49.0 3.99e-01 78.8% 43.0%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.67 51.0 4.63e-01 86.5% 82.7%
3p2mA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.65 50.0 3.09e-01 82.7% 70.8%
3dplC03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 47.0 4.15e-01 80.8% 51.8%
2v57A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 49.0 3.46e-01 84.6% 27.5%
3kdgA02 3.30.1370.100 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › MutL, C-terminal domain, regulatory subdomain 0.64 46.0 3.88e-01 80.8% 43.6%
6l3tA01 1.20.1440.80 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain 0.63 44.0 3.01e-01 75.0% 81.4%
1uyjA01 3.30.360.60 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › 0.62 43.0 3.85e-01 88.5% 48.8%
4tvsA00 3.40.50.12190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 46.0 3.01e-01 80.8% 63.4%
3tixB03 3.40.50.11490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 42.0 3.13e-01 78.8% 28.2%
1v66A00 1.10.720.30 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain 0.59 45.0 4.21e-01 82.7% 73.8%
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.59 43.0 4.41e-01 84.6% 96.1%
3vw5A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.58 48.0 2.90e-01 94.2% 84.1%
3qitB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 43.0 2.79e-01 84.6% 23.7%
1x3zA03 1.10.1740.90 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.58 44.0 3.95e-01 94.2% 78.4%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 42.0 3.76e-01 76.9% 71.8%
3dkqA02 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.57 40.0 4.23e-01 75.0% 91.5%
2e1qC10 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.56 44.0 3.40e-01 90.4% 51.6%
3dd9D02 6.10.140.2060 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 4.10e-01 80.8% 100.0%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.55 45.0 2.75e-01 94.2% 91.9%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3714100 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.91 65.0 5.80e-01 75.0% 55.7%
3742957 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.88 71.0 6.76e-01 86.5% 78.3%
4913800 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.85 70.0 6.01e-01 88.5% 70.9%
3398172 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.84 64.0 4.98e-01 80.8% 41.9%
3699966 148.1.3.10 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_6 0.84 67.0 5.16e-01 86.5% 49.1%
3648830 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.83 66.0 5.57e-01 86.5% 54.1%
5048048 4957.1.1.9 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit › HAAS 0.83 68.0 5.97e-01 88.5% 80.0%
3620454 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.83 61.0 4.34e-01 80.8% 27.3%
5082960 159.1.2.35 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › HAAS 0.83 71.0 6.17e-01 92.3% 89.3%
3503648 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.82 65.0 6.19e-01 84.6% 80.0%
3581450 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.82 57.0 5.62e-01 73.1% 70.9%
3405161 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.81 62.0 4.54e-01 84.6% 53.6%
4953903 194.1.1.7 alpha complex topology › Serum albumin-like › Serum albumin-like › Serum albumin-like › Zn_ribbon_2 0.81 61.0 5.10e-01 80.8% 50.6%
3809576 103.4.1.5 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 0.80 63.0 5.89e-01 86.5% 78.5%
3414570 190.1.1.5 alpha arrays › HMG-box-like › HMG-box › HMG-box › Protamine_like 0.79 56.0 4.96e-01 84.6% 52.0%
3426642 375.1.1.96 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › YABBY 0.79 61.0 6.21e-01 82.7% 86.0%
5084048 3831.1.1.15 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › HAAS 0.78 66.0 5.55e-01 92.3% 76.5%
3404381 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.78 55.0 5.87e-01 80.8% 86.7%
3930859 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.78 58.0 5.16e-01 80.8% 60.0%
4061431 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.78 58.0 5.93e-01 80.8% 88.0%
3506153 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.78 59.0 5.07e-01 82.7% 53.0%
4302906 148.1.3.179 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_BCS1 0.77 50.0 4.83e-01 71.2% 58.3%
3497163 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.77 61.0 5.28e-01 86.5% 56.2%
3970206 857.1.1.0 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like 0.77 59.0 5.54e-01 84.6% 72.3%
3248213 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.77 66.0 4.09e-01 92.3% 18.8%
2075031 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.76 55.0 4.07e-01 78.8% 30.5%
3925598 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.76 65.0 4.49e-01 96.2% 82.9%
4339297 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 66.0 4.44e-01 98.1% 63.6%
3587822 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.75 55.0 4.12e-01 78.8% 31.5%
3937267 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.75 60.0 4.07e-01 90.4% 70.3%
3970007 3502.1.1.0 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein 0.74 57.0 5.07e-01 84.6% 68.0%
3715403 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.73 53.0 5.12e-01 78.8% 76.7%
3550406 541.1.1.0 alpha duplicates or obligate multimers › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit 0.72 51.0 5.19e-01 76.9% 84.0%
3402349 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.72 53.0 5.08e-01 80.8% 73.3%
3578019 821.1.1.8 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › ANKLE2_3rd 0.71 55.0 4.36e-01 86.5% 41.9%
4029774 1056.1.1.0 a+b two layers › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain 0.68 57.0 3.49e-01 98.1% 33.4%
3999832 541.1.1.2 alpha duplicates or obligate multimers › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit › Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit › Dpy-30 0.65 43.0 4.42e-01 71.2% 74.0%
3811338 109.4.1.2260 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_6, TPR_19 0.64 54.0 3.39e-01 94.2% 58.6%
5031345 2006.1.4.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN 0.64 50.0 3.85e-01 90.4% 60.8%
3403695 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.61 45.0 3.61e-01 86.5% 65.6%
3734404 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.59 45.0 3.95e-01 84.6% 65.0%
4976420 1074.1.1.0 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.57 44.0 3.67e-01 92.3% 82.9%
D2 medium residues 98-157
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 37.8 1.50e-09 98.3% 11.9%
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.86 62.0 6.21e-01 75.0% 75.4%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.86 70.0 5.14e-01 86.7% 36.1%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.85 61.0 6.63e-01 75.0% 100.0%
3rkvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.85 67.0 4.94e-01 86.7% 34.7%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 70.0 6.98e-01 100.0% 87.1%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 67.0 6.84e-01 86.7% 87.9%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.83 66.0 4.46e-01 85.0% 50.3%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.81 72.0 5.09e-01 96.7% 67.8%
8b9zK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 68.0 5.83e-01 90.0% 59.3%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.80 71.0 4.18e-01 95.0% 14.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 67.0 6.21e-01 100.0% 73.0%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.79 67.0 5.58e-01 100.0% 55.6%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.79 66.0 5.70e-01 100.0% 59.3%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 70.0 6.87e-01 98.3% 90.5%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 66.0 6.72e-01 100.0% 93.1%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.78 66.0 6.65e-01 100.0% 90.2%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 68.0 4.60e-01 95.0% 78.9%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.78 65.0 5.22e-01 93.3% 58.0%
2rd3D00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.77 64.0 4.33e-01 100.0% 25.2%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 68.0 5.71e-01 100.0% 59.2%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.77 63.0 5.02e-01 100.0% 46.2%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 67.0 4.62e-01 96.7% 56.6%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.76 56.0 4.98e-01 80.0% 55.3%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.76 65.0 4.34e-01 98.3% 69.8%
5ux1D00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 68.0 4.60e-01 96.7% 56.9%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 64.0 4.43e-01 100.0% 28.4%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 64.0 5.88e-01 98.3% 73.0%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 66.0 4.88e-01 96.7% 72.4%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.75 68.0 5.93e-01 100.0% 70.5%
7t7kA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.75 66.0 5.27e-01 98.3% 71.2%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.75 59.0 4.77e-01 86.7% 46.1%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 64.0 4.21e-01 96.7% 71.0%
3zgxA02 6.10.140.1720 Special › Helix non-globular › Helix Hairpins › 0.74 63.0 5.52e-01 100.0% 63.7%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 64.0 5.87e-01 100.0% 74.7%
4cpgA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.73 52.0 4.96e-01 76.7% 65.2%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 61.0 4.64e-01 98.3% 56.4%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.72 63.0 4.96e-01 100.0% 48.8%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.71 57.0 5.54e-01 100.0% 80.6%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 63.0 4.29e-01 100.0% 65.6%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.71 58.0 3.99e-01 100.0% 25.4%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 62.0 6.27e-01 100.0% 98.3%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 60.0 5.63e-01 98.3% 77.6%
4pdyA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.70 60.0 4.02e-01 96.7% 61.4%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.69 48.0 4.44e-01 73.3% 55.7%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.69 56.0 4.19e-01 91.7% 73.5%
2db7A01 6.10.250.980 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 50.0 5.26e-01 78.3% 88.7%
2l35A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.68 54.0 5.41e-01 90.0% 88.9%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.66 57.0 4.35e-01 98.3% 57.2%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 55.0 4.44e-01 98.3% 61.2%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 57.0 5.48e-01 100.0% 84.5%
1wncB00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 51.0 4.70e-01 100.0% 65.4%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.62 53.0 5.21e-01 100.0% 92.3%
1exzB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 48.0 3.79e-01 100.0% 37.9%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4977369 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.93 87.0 5.53e-01 100.0% 24.4%
2323867 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.93 85.0 8.49e-01 98.3% 95.1%
4970593 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.93 87.0 5.51e-01 100.0% 24.0%
3397137 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.92 73.0 6.65e-01 86.7% 66.7%
4959101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 84.0 5.41e-01 100.0% 24.5%
4999065 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.90 75.0 5.39e-01 98.3% 34.2%
4956224 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 83.0 5.38e-01 100.0% 26.4%
3993981 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 85.0 5.50e-01 100.0% 26.7%
4939089 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.90 71.0 4.42e-01 85.0% 17.7%
5073476 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.89 81.0 5.29e-01 100.0% 25.5%
3348106 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.89 76.0 4.78e-01 100.0% 20.4%
4202466 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.89 64.0 7.25e-01 75.0% 100.0%
3714352 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.88 73.0 5.75e-01 98.3% 45.0%
4473366 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.88 75.0 6.94e-01 100.0% 73.3%
4977784 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.88 72.0 4.71e-01 98.3% 22.6%
3983659 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.87 64.0 6.20e-01 80.0% 70.8%
3795985 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.87 70.0 6.21e-01 86.7% 62.4%
4485576 1.1.17.4 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 0.87 77.0 4.78e-01 95.0% 45.5%
3651038 192.29.1.221 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29520 0.87 73.0 5.58e-01 100.0% 42.3%
4998819 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.86 72.0 5.48e-01 98.3% 41.5%
4999337 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.86 72.0 5.20e-01 98.3% 34.8%
3588519 101.1.2.49 alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.86 71.0 5.02e-01 88.3% 35.2%
4977429 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.85 71.0 5.31e-01 98.3% 38.6%
3984016 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.85 72.0 6.23e-01 100.0% 61.1%
3955489 2484.1.1.211 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB 0.85 73.0 4.86e-01 100.0% 26.2%
3472169 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.85 72.0 5.20e-01 100.0% 35.5%
3356933 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.85 69.0 4.97e-01 86.7% 41.9%
3642421 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.84 70.0 5.42e-01 100.0% 43.2%
4883924 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.84 71.0 6.41e-01 100.0% 68.8%
3346803 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.84 70.0 4.34e-01 100.0% 18.0%
3681637 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.83 69.0 4.86e-01 100.0% 30.9%
4544002 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.83 64.0 6.90e-01 83.3% 98.0%
3286637 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.83 69.0 4.91e-01 98.3% 32.7%
4978165 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.82 68.0 4.66e-01 100.0% 27.0%
3192393 2004.1.1.430 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn 0.82 70.0 3.92e-01 100.0% 8.9%
3253283 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.82 73.0 6.11e-01 100.0% 60.0%
4951260 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.81 68.0 5.12e-01 100.0% 39.3%
5005094 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.81 68.0 4.68e-01 100.0% 28.2%
4972401 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.81 74.0 4.94e-01 100.0% 88.4%
3732909 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 67.0 6.05e-01 100.0% 67.5%
4146694 192.29.1.277 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Dynamitin 0.81 68.0 6.66e-01 100.0% 84.6%
3796589 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.80 67.0 5.56e-01 100.0% 54.0%
2524047 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.80 70.0 5.06e-01 96.7% 82.1%
4667859 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.80 71.0 5.61e-01 100.0% 50.4%
3755476 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.80 70.0 4.89e-01 100.0% 32.6%
3436926 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.80 70.0 6.52e-01 100.0% 77.0%
3474347 109.4.1.83 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf 0.79 67.0 3.84e-01 100.0% 10.1%
3594586 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.79 69.0 5.84e-01 100.0% 60.0%
4774281 1147.1.1.1 alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL 0.79 66.0 5.35e-01 100.0% 50.5%
3817615 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.78 67.0 5.55e-01 100.0% 54.3%
3580316 4082.1.1.0 alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain 0.78 55.0 6.06e-01 75.0% 100.0%
4590389 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.77 63.0 4.70e-01 100.0% 35.5%
3224003 9001.1.1.3 alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMPIT 0.77 63.0 5.80e-01 100.0% 68.8%
4961346 3805.1.1.1 alpha bundles › Hypothetical protein TTHB059 › Hypothetical protein TTHB059 › Hypothetical protein TTHB059 › DUF3209 0.77 65.0 5.16e-01 100.0% 46.7%
3622515 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 65.0 5.79e-01 100.0% 65.9%
5005724 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.77 70.0 4.58e-01 98.3% 100.0%
3931593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 62.0 5.63e-01 100.0% 66.3%
3718782 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.76 60.0 4.02e-01 86.7% 25.7%
3259629 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 62.0 5.29e-01 100.0% 55.0%
4124331 192.15.1.76 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › CUPID 0.76 66.0 5.34e-01 100.0% 51.8%
3970799 602.3.1.0 alpha arrays › L-aspartase middle domain-like › TssK neck domain › TssK neck domain 0.74 63.0 5.04e-01 96.7% 51.7%
3919688 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 62.0 4.12e-01 100.0% 23.7%
3386700 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.72 64.0 4.05e-01 100.0% 50.2%
2914508 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.71 52.0 3.36e-01 80.0% 17.3%
3582116 1147.1.1.1 alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL 0.70 62.0 4.96e-01 100.0% 85.8%
3786466 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.70 60.0 4.14e-01 100.0% 28.4%
1289445 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.64 53.0 3.38e-01 96.7% 43.7%
3352211 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.62 51.0 4.55e-01 95.0% 75.6%
3605352 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 49.0 4.06e-01 100.0% 64.2%
D3 medium residues 188-273
PDB
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1q2wA03 1.10.1840.10 Mainly Alpha › Orthogonal Bundle › main proteinase (3clpro) structure, domain 3 › main proteinase (3clpro) structure, domain 3 0.62 50.0 4.77e-01 97.7% 74.0%
3vw4A01 1.10.340.50 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › 0.60 44.0 4.36e-01 86.0% 73.9%
3qvmB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 48.0 3.41e-01 89.5% 61.8%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.57 46.0 3.55e-01 88.4% 64.4%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.57 45.0 4.34e-01 86.0% 81.4%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 45.0 4.54e-01 87.2% 85.1%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 44.0 4.22e-01 87.2% 88.2%
3hzsA00 1.10.3810.10 Mainly Alpha › Orthogonal Bundle › Penicillin binding protein transpeptidase fold › Biosynthetic peptidoglycan transglycosylase-like 0.56 49.0 3.76e-01 100.0% 61.7%
1r3dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 45.0 3.24e-01 89.5% 64.6%
2yqzA02 1.10.8.900 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.55 37.0 4.06e-01 98.8% 86.8%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 42.0 4.04e-01 84.9% 85.1%
4behA01 1.10.10.1410 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.54 34.0 3.80e-01 87.2% 85.9%
3rjvA02 1.25.40.740 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 33.0 3.72e-01 84.9% 82.8%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.52 41.0 3.69e-01 87.2% 60.3%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 41.0 3.85e-01 87.2% 81.5%
3oqvA00 3.40.50.11710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase 0.51 41.0 3.20e-01 91.9% 82.0%
2ef8A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.50 31.0 3.17e-01 94.2% 63.1%
6qwvH02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.50 29.0 3.32e-01 79.1% 82.8%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3084955 6001.1.1.0 alpha arrays › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain 0.61 51.0 4.59e-01 98.8% 65.8%
2754430 6001.1.1.1 alpha arrays › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain › Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain › Peptidase_C30 0.61 51.0 4.51e-01 98.8% 63.7%
4624818 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.60 47.0 4.65e-01 84.9% 87.8%
4143825 5046.1.1.123 extended segments › F-type ATP synthase subunit b › F-type ATP synthase subunit b › F-type ATP synthase subunit b › OSCP 0.57 41.0 2.71e-01 87.2% 17.8%
4024393 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.57 44.0 4.53e-01 88.4% 88.7%
4283815 1.1.9.5 beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.56 45.0 3.25e-01 89.5% 85.9%
3457160 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.56 46.0 3.25e-01 90.7% 57.1%
4090355 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 45.0 3.63e-01 88.4% 67.5%
3978383 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.53 41.0 3.38e-01 88.4% 87.0%
5077884 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.52 42.0 4.30e-01 91.9% 95.0%
2777206 3909.1.1.0 alpha bundles › NisB C-terminal helical domain › NisB C-terminal helical domain › NisB C-terminal helical domain 0.52 39.0 2.83e-01 80.2% 81.3%
3320708 610.2.1.1 alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 › Sec23_helical 0.51 39.0 3.59e-01 84.9% 65.0%
4584156 2005.1.1.31 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CDPS 0.51 42.0 3.20e-01 93.0% 76.4%
D4 medium residues 274-328
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ewcA03 1.20.120.1660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 49.0 4.46e-01 90.9% 52.0%
2qsbA00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.70 55.0 4.82e-01 87.3% 96.5%
2guzB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.68 53.0 5.01e-01 94.5% 70.8%
5jj6B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 47.0 3.89e-01 89.1% 43.8%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.65 55.0 5.32e-01 92.7% 90.2%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.64 54.0 4.21e-01 90.9% 44.7%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 52.0 5.16e-01 89.1% 89.5%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.63 48.0 4.59e-01 89.1% 69.7%
3t57A02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.60 40.0 3.68e-01 78.2% 50.7%
3q23A03 6.10.140.1360 Special › Helix non-globular › Helix Hairpins › 0.60 45.0 4.19e-01 94.5% 62.5%
4nv0A02 1.10.150.340 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain 0.59 48.0 4.24e-01 92.7% 67.1%
3hgkE00 1.20.1280.110 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.56 44.0 4.01e-01 90.9% 81.8%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 45.0 4.09e-01 96.4% 75.6%
3e99A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 40.0 3.00e-01 81.8% 80.4%
1yt3A03 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.54 38.0 3.48e-01 80.0% 98.8%
4toiA02 1.10.287.610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.52 39.0 4.18e-01 92.7% 93.8%
1z4hA01 1.10.238.160 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.52 33.0 3.27e-01 78.2% 60.3%
4am6A03 3.30.420.580 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.51 40.0 2.65e-01 89.1% 23.6%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988683 4168.1.1.1 alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › HAMP 0.66 39.0 3.99e-01 83.6% 58.2%
3934422 372.2.1.1 a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.61 50.0 3.71e-01 100.0% 57.6%
4530492 3455.1.1.0 alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.61 43.0 4.42e-01 80.0% 84.0%
3782390 3444.1.1.3 alpha arrays › DP domain › DP domain › DP domain › Hit1_C 0.59 49.0 4.31e-01 94.5% 79.5%
1903632 276.1.1.1 a+b three layers › L-sulfolactate dehydrogenase-like › L-sulfolactate dehydrogenase-like › L-sulfolactate dehydrogenase-like › Ldh_2 0.54 43.0 2.76e-01 94.5% 46.8%
4021046 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.51 37.0 2.39e-01 81.8% 51.7%
D5 medium residues 329-377_417-489
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20286.4 best divDNApol 53.8 1.50e-14 98.4% 13.9%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.61 46.0 3.82e-01 97.5% 46.4%
3ipiA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 45.0 3.50e-01 80.3% 59.3%
5utkA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 27.0 3.04e-01 77.9% 57.8%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4091380 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.55 31.0 3.29e-01 84.4% 60.9%
3240388 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 38.0 2.87e-01 73.0% 83.4%
D6 medium residues 378-416_503-552
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3uarA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 40.0 3.79e-01 91.0% 64.5%
3vw7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 44.0 3.21e-01 100.0% 97.9%
2vsoF01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 35.0 2.61e-01 89.9% 27.3%
1hufA00 3.30.1570.10 Alpha Beta › 2-Layer Sandwich › YopH tyrosine phosphatase N-terminal domain › Protein-tyrosine phosphatase, YopH, N-terminal domain 0.51 35.0 3.19e-01 71.9% 99.2%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.51 29.0 2.92e-01 83.1% 53.3%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3425881 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.64 25.0 2.43e-01 100.0% 30.5%
4942573 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 28.0 3.33e-01 93.3% 65.0%
3612943 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.55 39.0 3.39e-01 74.2% 79.3%
4887308 275.1.1.0 a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase 0.53 23.0 2.85e-01 88.8% 60.3%
4870080 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 39.0 2.91e-01 78.7% 32.9%
3788152 171.1.1.0 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like 0.52 39.0 3.34e-01 79.8% 64.8%
2754401 3343.1.1.2 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.52 45.0 2.68e-01 100.0% 12.8%
3248314 206.1.1.76 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1, Pkinase_fungal 0.51 36.0 2.40e-01 73.0% 88.3%
4319401 2003.1.2.8 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2,Pyr_redox_2 0.50 41.0 2.82e-01 94.4% 82.4%
D7 medium residues 559-684
PDB
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA06 3.40.1820.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › DnaQ-like 3'-5' exonuclease 0.72 52.0 6.00e-01 85.7% 100.0%
3k59A07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.71 51.0 4.87e-01 100.0% 64.8%
4b08A08 3.40.1820.20 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › B family DNA polymerase, thumb domain, alpha/beta motif 0.66 41.0 4.92e-01 88.9% 96.2%
4qclA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.62 49.0 4.45e-01 100.0% 63.1%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3945475 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.71 50.0 4.73e-01 100.0% 61.3%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.66 50.0 4.31e-01 100.0% 51.5%
4547010 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.63 48.0 4.24e-01 100.0% 56.1%