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pre3_saliva_scaffold_7_prodigal-single.1__X__X__00266
Bact-Virpre3_saliva_scaffold_7_prodigal-single.1__X__X__00266
Identity
- Kingdom:
- phage
Quality
70.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-142
Domain cluster:
representative
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 61.0 | 5.31e-01 | 78.0% | 93.8% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 59.0 | 5.34e-01 | 75.9% | 97.9% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.80 | 74.0 | 5.69e-01 | 99.3% | 85.5% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.78 | 59.0 | 6.54e-01 | 91.5% | 97.4% |
| 4p79A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.78 | 66.0 | 6.06e-01 | 90.8% | 100.0% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.77 | 51.0 | 5.41e-01 | 70.2% | 77.0% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.76 | 66.0 | 6.24e-01 | 96.5% | 78.9% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.76 | 53.0 | 5.49e-01 | 73.8% | 76.1% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 52.0 | 5.50e-01 | 70.9% | 78.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 61.0 | 6.56e-01 | 89.4% | 100.0% |
| 3x29A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.75 | 63.0 | 5.99e-01 | 90.1% | 100.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.75 | 59.0 | 6.40e-01 | 91.5% | 100.0% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.75 | 57.0 | 4.71e-01 | 79.4% | 88.6% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 56.0 | 4.58e-01 | 78.0% | 88.0% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.74 | 62.0 | 5.51e-01 | 89.4% | 74.5% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 55.0 | 4.43e-01 | 77.3% | 88.3% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.74 | 52.0 | 5.64e-01 | 71.6% | 97.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 51.0 | 5.75e-01 | 70.2% | 96.2% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.73 | 53.0 | 4.91e-01 | 73.8% | 96.6% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.73 | 54.0 | 4.59e-01 | 77.3% | 48.4% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 58.0 | 5.41e-01 | 94.3% | 68.0% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.73 | 55.0 | 5.13e-01 | 79.4% | 69.3% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 45.0 | 4.98e-01 | 87.9% | 77.9% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 43.0 | 5.24e-01 | 70.2% | 93.4% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.70 | 63.0 | 5.66e-01 | 97.2% | 77.2% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.70 | 64.0 | 5.81e-01 | 100.0% | 77.8% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.70 | 61.0 | 5.40e-01 | 94.3% | 78.8% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.69 | 46.0 | 5.45e-01 | 83.0% | 100.0% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 53.0 | 5.27e-01 | 88.7% | 76.5% |
| 1at9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 57.0 | 4.85e-01 | 96.5% | 54.8% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 47.0 | 4.40e-01 | 70.2% | 79.8% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.68 | 55.0 | 5.23e-01 | 88.7% | 73.3% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 61.0 | 5.96e-01 | 99.3% | 96.8% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 61.0 | 5.69e-01 | 100.0% | 96.6% |
| 4y9jA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 55.0 | 5.47e-01 | 88.7% | 93.3% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.66 | 59.0 | 5.21e-01 | 100.0% | 66.0% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.66 | 53.0 | 4.45e-01 | 83.7% | 64.2% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 60.0 | 5.84e-01 | 100.0% | 95.5% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 56.0 | 5.43e-01 | 92.2% | 85.4% |
| 1r2jA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 59.0 | 5.88e-01 | 100.0% | 95.8% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 59.0 | 5.81e-01 | 100.0% | 94.1% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 56.0 | 5.55e-01 | 94.3% | 94.7% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 49.0 | 5.31e-01 | 78.7% | 96.6% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 55.0 | 4.47e-01 | 94.3% | 49.6% |
| 1egdA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 56.0 | 5.61e-01 | 93.6% | 97.2% |
| 2uxwA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 58.0 | 5.33e-01 | 100.0% | 80.1% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 46.0 | 3.73e-01 | 73.8% | 80.1% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 55.0 | 5.55e-01 | 93.6% | 95.8% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 58.0 | 5.77e-01 | 100.0% | 95.9% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.64 | 46.0 | 4.56e-01 | 75.2% | 71.9% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 57.0 | 5.53e-01 | 99.3% | 91.8% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 49.0 | 4.04e-01 | 80.9% | 85.9% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.63 | 52.0 | 4.73e-01 | 86.5% | 94.0% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 57.0 | 5.54e-01 | 100.0% | 97.4% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 50.0 | 4.32e-01 | 93.6% | 54.7% |
| 7w9wA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 53.0 | 4.31e-01 | 90.1% | 53.1% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.63 | 50.0 | 5.39e-01 | 95.7% | 100.0% |
| 3am6A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 55.0 | 4.70e-01 | 97.2% | 84.4% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 52.0 | 5.31e-01 | 96.5% | 97.8% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 49.0 | 5.05e-01 | 90.1% | 93.2% |
| 4qiqA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.59 | 52.0 | 3.67e-01 | 96.5% | 49.9% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.59 | 53.0 | 3.92e-01 | 97.2% | 83.2% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 51.0 | 4.01e-01 | 95.7% | 89.4% |
| 4tpjA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 53.0 | 3.66e-01 | 97.2% | 43.6% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.58 | 47.0 | 5.07e-01 | 93.6% | 100.0% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.58 | 40.0 | 3.96e-01 | 70.2% | 72.0% |
| 2pziB03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 40.0 | 3.91e-01 | 74.5% | 66.7% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 50.0 | 3.65e-01 | 97.9% | 49.5% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 39.0 | 3.90e-01 | 70.9% | 94.6% |
| 7e5aB02 | 1.20.1000.10 | Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain | 0.51 | 36.0 | 3.45e-01 | 72.3% | 70.1% |
ECOD (83)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4025838 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.83 | 76.0 | 7.22e-01 | 95.7% | 100.0% |
| 3874696 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.82 | 71.0 | 6.76e-01 | 90.1% | 93.8% |
| 3937142 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.82 | 76.0 | 7.06e-01 | 97.9% | 100.0% |
| 3171105 | 174.1.1.60 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF30036 | 0.81 | 72.0 | 6.81e-01 | 93.6% | 100.0% |
| 3599715 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.81 | 74.0 | 7.18e-01 | 95.7% | 98.1% |
| 3758651 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.81 | 75.0 | 6.64e-01 | 96.5% | 96.3% |
| 3225163 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.81 | 68.0 | 7.09e-01 | 87.9% | 100.0% |
| 3939680 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.81 | 61.0 | 5.06e-01 | 78.0% | 83.8% |
| 3870615 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.80 | 68.0 | 7.18e-01 | 87.2% | 100.0% |
| 3797208 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.80 | 75.0 | 7.34e-01 | 100.0% | 92.7% |
| 3220098 | 633.23.1.14 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_3 | 0.80 | 70.0 | 6.24e-01 | 92.2% | 100.0% |
| 3578008 | 601.1.2.100 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF31009 | 0.79 | 70.0 | 6.80e-01 | 93.6% | 92.3% |
| 4455505 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.79 | 62.0 | 6.83e-01 | 93.6% | 100.0% |
| 3824606 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.79 | 68.0 | 6.26e-01 | 90.8% | 77.7% |
| 3880919 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.79 | 68.0 | 6.71e-01 | 90.8% | 95.3% |
| 3717920 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.79 | 73.0 | 7.09e-01 | 100.0% | 96.8% |
| 3601571 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.79 | 66.0 | 6.58e-01 | 88.7% | 100.0% |
| 3812310 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 64.0 | 6.24e-01 | 92.2% | 78.1% |
| 3838013 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.78 | 69.0 | 6.35e-01 | 94.3% | 82.2% |
| 4497407 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 66.0 | 6.23e-01 | 92.2% | 76.4% |
| 3494149 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.77 | 71.0 | 6.74e-01 | 98.6% | 90.3% |
| 3878144 | 601.1.2.2 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ | 0.77 | 66.0 | 6.82e-01 | 90.8% | 95.6% |
| 4525096 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.77 | 68.0 | 6.47e-01 | 93.6% | 81.2% |
| 2512963 | 633.21.1.1 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 | 0.77 | 63.0 | 6.57e-01 | 91.5% | 92.4% |
| 3251841 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.77 | 67.0 | 6.86e-01 | 92.2% | 96.3% |
| 3826910 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.77 | 65.0 | 6.22e-01 | 94.3% | 78.8% |
| 3956224 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.77 | 64.0 | 5.91e-01 | 94.3% | 69.4% |
| 3600968 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.77 | 69.0 | 6.92e-01 | 95.0% | 97.9% |
| 4023646 | 174.1.1.88 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7641 | 0.77 | 64.0 | 6.75e-01 | 93.6% | 100.0% |
| 3688917 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.76 | 64.0 | 6.77e-01 | 89.4% | 100.0% |
| 3741398 | 632.1.1.8 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 | 0.76 | 62.0 | 6.44e-01 | 86.5% | 100.0% |
| 3483197 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 70.0 | 6.89e-01 | 99.3% | 100.0% |
| 3657913 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.75 | 65.0 | 6.01e-01 | 96.5% | 72.8% |
| 3517687 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.75 | 62.0 | 6.30e-01 | 87.9% | 92.9% |
| 3616821 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 62.0 | 6.48e-01 | 87.9% | 100.0% |
| 3211341 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 65.0 | 6.28e-01 | 94.3% | 90.6% |
| 4468935 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.75 | 64.0 | 6.61e-01 | 92.2% | 98.5% |
| 3579239 | 633.7.1.0 ↗ | alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like | 0.74 | 67.0 | 6.50e-01 | 97.2% | 100.0% |
| 3794464 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.74 | 56.0 | 4.33e-01 | 77.3% | 92.8% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.74 | 68.0 | 6.47e-01 | 98.6% | 100.0% |
| 3930618 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.74 | 66.0 | 6.71e-01 | 96.5% | 99.3% |
| 3974411 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.73 | 65.0 | 5.73e-01 | 95.7% | 91.2% |
| 3831865 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.73 | 64.0 | 6.64e-01 | 93.6% | 100.0% |
| 3401839 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 66.0 | 6.73e-01 | 96.5% | 100.0% |
| 3231982 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.73 | 66.0 | 6.16e-01 | 96.5% | 85.3% |
| 3327074 | 5001.1.1.122 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 | 0.73 | 54.0 | 4.20e-01 | 78.0% | 95.5% |
| 3403588 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.73 | 54.0 | 4.40e-01 | 77.3% | 68.5% |
| 3938057 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.72 | 62.0 | 5.59e-01 | 92.2% | 88.4% |
| 4999598 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.72 | 62.0 | 6.42e-01 | 99.3% | 100.0% |
| 3601384 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.72 | 63.0 | 5.98e-01 | 94.3% | 100.0% |
| 3931307 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.72 | 64.0 | 6.34e-01 | 96.5% | 100.0% |
| 3970792 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.71 | 57.0 | 6.08e-01 | 94.3% | 98.3% |
| 3546181 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.71 | 54.0 | 4.43e-01 | 79.4% | 77.9% |
| 3770345 | 602.2.1.3 ↗ | alpha arrays › L-aspartase middle domain-like › RNA-binding protein She2p › RNA-binding protein She2p › PPP1R21_helical | 0.71 | 63.0 | 5.23e-01 | 96.5% | 100.0% |
| 3265343 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.71 | 64.0 | 5.03e-01 | 97.9% | 78.9% |
| 4026849 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.71 | 61.0 | 5.01e-01 | 92.9% | 60.8% |
| 3390036 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.70 | 54.0 | 4.28e-01 | 80.9% | 94.4% |
| 3556381 | 3755.3.1.530 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPP1R21_helical | 0.70 | 63.0 | 5.15e-01 | 98.6% | 95.8% |
| 5082391 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.70 | 60.0 | 5.34e-01 | 93.6% | 69.5% |
| 3573603 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.69 | 60.0 | 5.74e-01 | 95.0% | 81.2% |
| 3931007 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.69 | 56.0 | 4.32e-01 | 85.1% | 95.3% |
| 4011437 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.69 | 60.0 | 4.96e-01 | 100.0% | 53.9% |
| 3389297 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.69 | 61.0 | 4.92e-01 | 97.2% | 81.7% |
| 3193097 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.68 | 63.0 | 5.17e-01 | 100.0% | 84.5% |
| 4985142 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.68 | 60.0 | 5.21e-01 | 96.5% | 98.1% |
| 4947845 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.68 | 60.0 | 5.24e-01 | 99.3% | 99.1% |
| 5077822 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.66 | 58.0 | 5.16e-01 | 96.5% | 68.3% |
| 3750717 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 58.0 | 4.63e-01 | 94.3% | 81.8% |
| 4947622 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.65 | 57.0 | 5.86e-01 | 95.0% | 100.0% |
| 3903091 | 277.1.1.0 ↗ | a+b two layers › PX domain › PX domain › PX domain | 0.65 | 48.0 | 3.54e-01 | 77.3% | 57.2% |
| 3225916 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.65 | 50.0 | 4.03e-01 | 81.6% | 85.3% |
| 3922718 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.65 | 56.0 | 4.55e-01 | 94.3% | 85.9% |
| 3288535 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.65 | 59.0 | 5.75e-01 | 99.3% | 91.6% |
| 3939088 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.65 | 56.0 | 4.57e-01 | 95.0% | 87.0% |
| 3883270 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.64 | 54.0 | 4.33e-01 | 93.6% | 87.9% |
| 3243512 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.63 | 51.0 | 3.98e-01 | 86.5% | 81.3% |
| 3782576 | 174.1.1.10 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Kei1 | 0.62 | 53.0 | 5.22e-01 | 91.5% | 92.0% |
| 1406524 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.62 | 49.0 | 4.66e-01 | 83.0% | 78.3% |
| 3686059 | 5001.1.1.133 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Git3, GPR_Gpa2_C | 0.62 | 54.0 | 4.23e-01 | 97.2% | 88.6% |
| 3481085 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.61 | 54.0 | 4.26e-01 | 95.7% | 75.3% |
| 3273576 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.61 | 53.0 | 4.35e-01 | 93.6% | 90.6% |
| 3400202 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 51.0 | 5.27e-01 | 94.3% | 95.6% |
| 3233240 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 49.0 | 4.00e-01 | 93.6% | 89.5% |
D2
high
residues 170-292
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 35.0 | 3.77e-01 | 70.7% | 61.9% |
| 1iuqA01 | 1.10.1200.50 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal | 0.63 | 27.0 | 3.34e-01 | 80.5% | 61.8% |
| 4fwvA02 | 1.20.120.1680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 47.0 | 4.60e-01 | 78.9% | 85.8% |
| 5awwY00 | 1.10.3370.10 | Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain | 0.61 | 52.0 | 3.63e-01 | 95.1% | 38.7% |
| 7w5gA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 47.0 | 3.35e-01 | 82.9% | 28.7% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.58 | 31.0 | 3.71e-01 | 95.9% | 75.9% |
| 7zviA01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.58 | 37.0 | 3.80e-01 | 94.3% | 65.6% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.57 | 31.0 | 3.40e-01 | 96.7% | 63.0% |
| 3edvA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 31.0 | 2.76e-01 | 93.5% | 35.0% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.55 | 44.0 | 3.72e-01 | 87.8% | 63.0% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 41.0 | 3.22e-01 | 92.7% | 37.5% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 38.0 | 3.17e-01 | 71.5% | 74.4% |
| 4gnkE00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.54 | 42.0 | 3.39e-01 | 82.9% | 80.0% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.53 | 31.0 | 3.51e-01 | 96.7% | 78.2% |
| 1wteB01 | 1.10.3250.10 | Mainly Alpha › Orthogonal Bundle › type ii restriction endonuclease, domain 1 › type ii restriction endonuclease, domain 1 | 0.53 | 46.0 | 4.36e-01 | 100.0% | 81.0% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 38.0 | 3.25e-01 | 74.8% | 74.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.52 | 42.0 | 3.73e-01 | 87.8% | 79.6% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.51 | 39.0 | 2.99e-01 | 80.5% | 96.7% |
| 3efoB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.51 | 41.0 | 3.87e-01 | 92.7% | 70.9% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 26.0 | 3.12e-01 | 94.3% | 77.3% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 38.0 | 3.61e-01 | 79.7% | 79.6% |
| 3crjC00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 36.0 | 3.24e-01 | 91.9% | 51.4% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3785673 | 3881.1.1.1 ↗ | alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 | 0.71 | 65.0 | 5.54e-01 | 100.0% | 69.5% |
| 3505833 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 39.0 | 3.38e-01 | 100.0% | 43.2% |
| 4095452 | 3755.3.1.299 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF445 | 0.59 | 45.0 | 3.97e-01 | 79.7% | 88.9% |
| 5069342 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 38.0 | 3.27e-01 | 100.0% | 42.1% |
| 3889164 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.58 | 37.0 | 4.25e-01 | 94.3% | 88.9% |
| 869286 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.57 | 39.0 | 3.92e-01 | 82.1% | 66.7% |
| 3327911 | 5051.1.1.15 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › K_trans | 0.57 | 48.0 | 3.45e-01 | 92.7% | 64.7% |
| 4298420 | 3755.3.1.299 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF445 | 0.57 | 42.0 | 3.17e-01 | 79.7% | 97.6% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.56 | 38.0 | 4.07e-01 | 83.7% | 78.0% |
| 3592441 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 39.0 | 3.61e-01 | 70.7% | 61.9% |
| 3888994 | 601.19.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein | 0.56 | 41.0 | 3.92e-01 | 77.2% | 64.8% |
| 3274792 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.54 | 39.0 | 3.40e-01 | 74.8% | 77.9% |
| 4034151 | 604.39.1.9 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 | 0.53 | 41.0 | 3.48e-01 | 82.9% | 71.2% |
| 4956383 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.53 | 36.0 | 3.87e-01 | 70.7% | 81.0% |
| 4998236 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.53 | 38.0 | 2.62e-01 | 74.0% | 76.9% |
| 3497437 | 3835.1.1.0 ↗ | alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein | 0.53 | 43.0 | 3.49e-01 | 89.4% | 91.8% |
| 3220017 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.53 | 41.0 | 3.90e-01 | 82.9% | 73.8% |
| 5062702 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.52 | 45.0 | 4.03e-01 | 100.0% | 82.1% |
| 4981593 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.52 | 42.0 | 3.52e-01 | 87.0% | 93.2% |
| 4997908 | 3542.1.1.1 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin | 0.52 | 45.0 | 3.47e-01 | 95.1% | 63.5% |
| 4526671 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.52 | 39.0 | 3.14e-01 | 79.7% | 66.0% |
| 4978685 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 36.0 | 3.17e-01 | 100.0% | 46.8% |
| 3303649 | 3755.3.1.310 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CemA | 0.51 | 37.0 | 3.38e-01 | 75.6% | 77.6% |
| 3233734 | 197.1.1.1 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › FERM_M | 0.51 | 36.0 | 3.63e-01 | 95.1% | 71.2% |