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pre3_saliva_scaffold_7_prodigal-single.1__X__X__00334
Bact-Virpre3_saliva_scaffold_7_prodigal-single.1__X__X__00334
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-99
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.70 | 47.0 | 4.77e-01 | 72.7% | 70.1% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 60.0 | 4.76e-01 | 93.9% | 50.0% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.66 | 59.0 | 4.59e-01 | 100.0% | 61.9% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.65 | 57.0 | 4.55e-01 | 94.9% | 84.5% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.65 | 53.0 | 3.50e-01 | 86.9% | 25.5% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 46.0 | 4.58e-01 | 72.7% | 82.2% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.65 | 45.0 | 4.32e-01 | 71.7% | 76.7% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.65 | 46.0 | 4.43e-01 | 73.7% | 100.0% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.65 | 52.0 | 4.29e-01 | 86.9% | 55.6% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 47.0 | 4.71e-01 | 84.8% | 91.3% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.60 | 45.0 | 4.61e-01 | 82.8% | 82.1% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.60 | 40.0 | 4.30e-01 | 78.8% | 79.5% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 48.0 | 4.67e-01 | 89.9% | 79.6% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.58 | 43.0 | 4.08e-01 | 83.8% | 64.5% |
| 2imsA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.58 | 46.0 | 3.97e-01 | 87.9% | 76.7% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 45.0 | 3.39e-01 | 84.8% | 97.5% |
| 3pmcA00 | 1.10.490.70 | Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain | 0.56 | 43.0 | 3.91e-01 | 82.8% | 61.4% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.55 | 44.0 | 3.95e-01 | 84.8% | 79.4% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 42.0 | 3.85e-01 | 80.8% | 61.7% |
| 3qxyA02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.55 | 43.0 | 3.68e-01 | 85.9% | 100.0% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 43.0 | 4.06e-01 | 82.8% | 89.7% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.54 | 43.0 | 4.51e-01 | 89.9% | 97.7% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.53 | 48.0 | 4.23e-01 | 99.0% | 68.0% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 46.0 | 4.04e-01 | 92.9% | 68.5% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 42.0 | 3.36e-01 | 84.8% | 86.6% |
| 6wk3A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 41.0 | 3.60e-01 | 81.8% | 97.2% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 38.0 | 3.46e-01 | 76.8% | 100.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 43.0 | 3.97e-01 | 87.9% | 82.0% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 46.0 | 4.03e-01 | 97.0% | 94.6% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.51 | 44.0 | 3.78e-01 | 93.9% | 61.0% |
ECOD (64)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3989144 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.84 | 76.0 | 5.81e-01 | 99.0% | 44.5% |
| 3927586 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.82 | 74.0 | 5.50e-01 | 96.0% | 46.2% |
| 4004724 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.81 | 75.0 | 5.62e-01 | 100.0% | 66.5% |
| 3642887 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 63.0 | 4.77e-01 | 89.9% | 50.0% |
| 3241376 | 3890.1.1.3 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › ZYG-11_interact | 0.74 | 64.0 | 5.03e-01 | 93.9% | 46.5% |
| 3580274 | 5050.1.1.5 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier | 0.72 | 58.0 | 5.04e-01 | 92.9% | 56.7% |
| 3357450 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.72 | 62.0 | 5.03e-01 | 92.9% | 55.1% |
| 3732518 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 57.0 | 4.35e-01 | 86.9% | 48.9% |
| 5013436 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 60.0 | 4.57e-01 | 90.9% | 49.5% |
| 3985920 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 55.0 | 4.26e-01 | 82.8% | 49.8% |
| 3964811 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 60.0 | 4.76e-01 | 92.9% | 57.0% |
| 3785418 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 63.0 | 4.82e-01 | 99.0% | 54.2% |
| 5032048 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 61.0 | 4.87e-01 | 93.9% | 52.6% |
| 4381849 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 62.0 | 4.94e-01 | 96.0% | 53.7% |
| 3863240 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 59.0 | 4.56e-01 | 92.9% | 52.3% |
| 3202076 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 56.0 | 4.35e-01 | 89.9% | 39.5% |
| 5054868 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 55.0 | 4.37e-01 | 92.9% | 42.0% |
| 3187357 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.69 | 46.0 | 4.17e-01 | 70.7% | 51.5% |
| 3478861 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 59.0 | 4.45e-01 | 94.9% | 42.9% |
| 4982917 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 59.0 | 4.67e-01 | 92.9% | 52.3% |
| 5022910 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 58.0 | 4.85e-01 | 92.9% | 57.6% |
| 5082844 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 58.0 | 4.65e-01 | 92.9% | 52.6% |
| 5072485 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 59.0 | 4.69e-01 | 94.9% | 51.3% |
| 4960302 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 58.0 | 4.64e-01 | 94.9% | 51.8% |
| 4149653 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 57.0 | 4.84e-01 | 91.9% | 57.9% |
| 3953262 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 56.0 | 4.49e-01 | 91.9% | 45.5% |
| 5051571 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 58.0 | 4.63e-01 | 94.9% | 49.7% |
| 4982547 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 58.0 | 4.55e-01 | 93.9% | 48.0% |
| 4527446 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 57.0 | 4.56e-01 | 94.9% | 49.5% |
| 3945105 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 57.0 | 4.42e-01 | 93.9% | 46.0% |
| 5012016 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.66 | 56.0 | 4.46e-01 | 93.9% | 48.3% |
| 4947640 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.66 | 45.0 | 3.38e-01 | 70.7% | 55.3% |
| 3323416 | 3831.1.1.7 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › DUF842 | 0.66 | 50.0 | 4.90e-01 | 79.8% | 85.7% |
| 3973761 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.66 | 55.0 | 4.49e-01 | 92.9% | 51.6% |
| 3174370 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 55.0 | 4.25e-01 | 93.9% | 45.3% |
| 3593720 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 55.0 | 4.10e-01 | 92.9% | 41.4% |
| 3588000 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 52.0 | 4.25e-01 | 88.9% | 57.9% |
| 3464273 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.64 | 44.0 | 4.20e-01 | 71.7% | 74.2% |
| 4002830 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 55.0 | 4.89e-01 | 96.0% | 75.5% |
| 3719607 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.63 | 43.0 | 3.71e-01 | 70.7% | 83.0% |
| 3279461 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 53.0 | 4.29e-01 | 93.9% | 50.0% |
| 5051930 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 49.0 | 3.86e-01 | 83.8% | 62.4% |
| 4009820 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.62 | 47.0 | 3.80e-01 | 81.8% | 77.1% |
| 3337831 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 49.0 | 3.86e-01 | 86.9% | 48.2% |
| 3861669 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.61 | 51.0 | 4.42e-01 | 90.9% | 66.5% |
| 134276 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.60 | 47.0 | 4.71e-01 | 84.8% | 91.3% |
| 3987321 | 164.1.1.30 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › DUF1430 | 0.59 | 52.0 | 4.88e-01 | 99.0% | 86.4% |
| 3663646 | 7064.1.1.5 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT | 0.59 | 48.0 | 4.47e-01 | 96.0% | 70.4% |
| 5050413 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 4.04e-01 | 97.0% | 76.0% |
| 4397666 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.58 | 41.0 | 3.44e-01 | 85.9% | 42.9% |
| 4987816 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.58 | 46.0 | 3.55e-01 | 88.9% | 37.4% |
| 4995305 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 39.0 | 4.00e-01 | 71.7% | 82.1% |
| 4945610 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.56 | 44.0 | 4.45e-01 | 88.9% | 99.0% |
| 3257705 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.56 | 44.0 | 4.53e-01 | 83.8% | 97.9% |
| 3834034 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.56 | 50.0 | 4.23e-01 | 100.0% | 80.6% |
| 3692017 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 47.0 | 4.21e-01 | 97.0% | 82.9% |
| 4888660 | 5067.1.1.1 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran | 0.54 | 46.0 | 3.49e-01 | 97.0% | 70.6% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.53 | 42.0 | 3.48e-01 | 81.8% | 94.1% |
| 3235672 | 192.29.1.137 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Otopetrin | 0.53 | 46.0 | 3.68e-01 | 96.0% | 77.6% |
| 3971983 | 3758.2.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB | 0.53 | 46.0 | 3.40e-01 | 99.0% | 97.5% |
| 4002999 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.52 | 41.0 | 4.10e-01 | 84.8% | 93.3% |
| 3963135 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 45.0 | 3.73e-01 | 99.0% | 62.1% |
| 3659174 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.51 | 37.0 | 3.70e-01 | 92.9% | 75.0% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.50 | 39.0 | 3.31e-01 | 82.8% | 95.3% |
D2
medium
residues 100-220
Domain cluster:
rep: membrane_protein_S22__YP_004940306__Saimiriine_betaherpesvirus_4__1535247__D123-237
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01027.27 best | Bax1-I | 84.3 | 1.60e-23 | 100.0% | 55.1% |
CATH (66)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.81 | 48.0 | 5.44e-01 | 76.0% | 77.4% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.79 | 56.0 | 5.68e-01 | 78.5% | 73.3% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.79 | 47.0 | 5.21e-01 | 83.5% | 73.0% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.78 | 50.0 | 4.76e-01 | 78.5% | 56.0% |
| 2a0bA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.78 | 51.0 | 5.22e-01 | 91.7% | 68.6% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.78 | 57.0 | 4.07e-01 | 76.9% | 68.8% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.77 | 58.0 | 5.17e-01 | 78.5% | 56.2% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.75 | 53.0 | 5.05e-01 | 74.4% | 63.5% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 51.0 | 5.10e-01 | 76.9% | 67.7% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.73 | 53.0 | 4.92e-01 | 80.2% | 59.1% |
| 2gnxA01 | 1.10.3450.30 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › | 0.73 | 46.0 | 4.01e-01 | 71.1% | 42.5% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.73 | 44.0 | 5.38e-01 | 76.9% | 94.8% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.73 | 49.0 | 5.05e-01 | 80.2% | 71.2% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 50.0 | 4.79e-01 | 77.7% | 62.5% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 52.0 | 4.00e-01 | 76.9% | 34.9% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.70 | 47.0 | 5.27e-01 | 73.6% | 89.0% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.70 | 53.0 | 5.20e-01 | 77.7% | 76.7% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 52.0 | 5.58e-01 | 76.9% | 97.0% |
| 2jvgA00 | 1.10.10.1270 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV | 0.69 | 32.0 | 4.07e-01 | 70.2% | 73.6% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.69 | 58.0 | 5.39e-01 | 95.0% | 73.5% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 50.0 | 4.38e-01 | 78.5% | 61.8% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 50.0 | 5.44e-01 | 76.9% | 95.9% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 49.0 | 4.07e-01 | 76.0% | 43.8% |
| 4ecgA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.67 | 51.0 | 3.59e-01 | 80.2% | 34.8% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.17e-01 | 76.0% | 53.6% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 36.0 | 4.30e-01 | 86.0% | 78.3% |
| 3r6nA02 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 46.0 | 4.31e-01 | 72.7% | 78.1% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 40.0 | 4.68e-01 | 91.7% | 86.2% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.65 | 43.0 | 4.55e-01 | 78.5% | 76.2% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 44.0 | 4.45e-01 | 78.5% | 70.3% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 48.0 | 4.51e-01 | 79.3% | 65.3% |
| 1g8xA06 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 47.0 | 3.45e-01 | 76.0% | 31.3% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 40.0 | 4.51e-01 | 78.5% | 83.5% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 46.0 | 4.89e-01 | 74.4% | 89.3% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 45.0 | 3.96e-01 | 73.6% | 70.5% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.63 | 41.0 | 3.85e-01 | 75.2% | 53.3% |
| 3tdoA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.62 | 44.0 | 3.42e-01 | 71.1% | 81.7% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 46.0 | 4.63e-01 | 76.9% | 90.1% |
| 6i57A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 33.0 | 3.29e-01 | 76.9% | 48.0% |
| 3fhnA03 | 1.10.357.100 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C | 0.62 | 44.0 | 3.97e-01 | 75.2% | 53.4% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 39.0 | 4.24e-01 | 79.3% | 77.0% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 45.0 | 3.86e-01 | 75.2% | 84.2% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 42.0 | 3.72e-01 | 70.2% | 54.2% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.61 | 48.0 | 3.96e-01 | 84.3% | 47.7% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.60 | 43.0 | 4.25e-01 | 75.2% | 89.5% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 44.0 | 4.70e-01 | 77.7% | 93.1% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 43.0 | 4.67e-01 | 76.0% | 89.2% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 40.0 | 3.91e-01 | 71.1% | 78.5% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.57 | 42.0 | 3.34e-01 | 75.2% | 83.1% |
| 3wvoC02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.56 | 39.0 | 3.84e-01 | 71.1% | 66.2% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 45.0 | 3.89e-01 | 85.1% | 87.3% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.55 | 38.0 | 4.14e-01 | 78.5% | 84.3% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 40.0 | 4.04e-01 | 79.3% | 75.4% |
| 2zcxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 48.0 | 4.02e-01 | 97.5% | 63.4% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.54 | 46.0 | 3.57e-01 | 91.7% | 75.5% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 34.0 | 3.61e-01 | 100.0% | 73.8% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.53 | 48.0 | 4.49e-01 | 100.0% | 95.4% |
| 5ziyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.53 | 46.0 | 3.97e-01 | 95.9% | 78.9% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 43.0 | 3.62e-01 | 87.6% | 84.6% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.52 | 44.0 | 3.79e-01 | 89.3% | 88.6% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 45.0 | 3.65e-01 | 92.6% | 93.2% |
| 7ccmB01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.52 | 46.0 | 4.38e-01 | 96.7% | 97.2% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.52 | 35.0 | 3.46e-01 | 91.7% | 63.6% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 40.0 | 3.79e-01 | 84.3% | 79.2% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.51 | 43.0 | 4.00e-01 | 97.5% | 71.4% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.50 | 42.0 | 3.68e-01 | 90.1% | 77.3% |
ECOD (76)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3386740 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.96 | 88.0 | 6.82e-01 | 100.0% | 49.6% |
| 4281235 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.95 | 89.0 | 7.05e-01 | 96.7% | 54.5% |
| 3989144 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.95 | 92.0 | 7.23e-01 | 100.0% | 55.5% |
| 3694381 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.95 | 88.0 | 7.01e-01 | 100.0% | 54.2% |
| 4434600 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.94 | 91.0 | 7.16e-01 | 100.0% | 58.2% |
| 3849233 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.94 | 86.0 | 6.87e-01 | 100.0% | 54.0% |
| 3980685 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.94 | 87.0 | 6.94e-01 | 96.7% | 56.3% |
| 3610437 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.93 | 87.0 | 7.03e-01 | 99.2% | 57.1% |
| 3577761 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.93 | 85.0 | 8.00e-01 | 100.0% | 82.1% |
| 3500534 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.93 | 84.0 | 6.77e-01 | 99.2% | 54.3% |
| 3476662 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.93 | 87.0 | 6.85e-01 | 100.0% | 52.7% |
| 4031559 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.92 | 83.0 | 6.71e-01 | 100.0% | 54.5% |
| 3716307 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.92 | 85.0 | 6.54e-01 | 99.2% | 48.8% |
| 4370734 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.91 | 84.0 | 6.80e-01 | 100.0% | 56.1% |
| 3626734 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.91 | 84.0 | 6.72e-01 | 100.0% | 54.5% |
| 5075726 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.91 | 82.0 | 6.51e-01 | 100.0% | 51.1% |
| 3964581 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.91 | 82.0 | 6.60e-01 | 100.0% | 54.3% |
| 3409798 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.90 | 83.0 | 6.64e-01 | 96.7% | 54.0% |
| 3936208 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.90 | 87.0 | 6.78e-01 | 100.0% | 55.1% |
| 4023988 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.89 | 85.0 | 6.75e-01 | 100.0% | 55.3% |
| 3165172 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.89 | 79.0 | 6.52e-01 | 98.3% | 56.5% |
| 3971997 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.88 | 80.0 | 6.53e-01 | 100.0% | 56.1% |
| 3392422 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 82.0 | 6.62e-01 | 100.0% | 55.3% |
| 3540947 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.88 | 84.0 | 6.67e-01 | 100.0% | 55.9% |
| 3213626 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 82.0 | 6.38e-01 | 97.5% | 52.2% |
| 3939603 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.87 | 84.0 | 6.63e-01 | 100.0% | 55.9% |
| 3511623 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 81.0 | 6.93e-01 | 100.0% | 66.1% |
| 4027411 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.86 | 79.0 | 6.41e-01 | 100.0% | 54.9% |
| 3403640 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.85 | 80.0 | 6.45e-01 | 100.0% | 55.8% |
| 3414049 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.83 | 76.0 | 6.20e-01 | 96.7% | 56.2% |
| 3399094 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.83 | 78.0 | 6.27e-01 | 99.2% | 56.3% |
| 3390912 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.81 | 76.0 | 6.03e-01 | 99.2% | 54.2% |
| 3403648 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.81 | 75.0 | 6.10e-01 | 100.0% | 57.2% |
| 3239865 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.81 | 59.0 | 5.73e-01 | 76.0% | 68.1% |
| 3416752 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.80 | 75.0 | 5.98e-01 | 100.0% | 56.4% |
| 3389855 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.80 | 75.0 | 6.02e-01 | 100.0% | 55.2% |
| 5041130 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.80 | 58.0 | 5.81e-01 | 75.2% | 74.4% |
| 3223631 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.80 | 60.0 | 5.34e-01 | 78.5% | 60.0% |
| 3908020 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.80 | 56.0 | 5.41e-01 | 76.9% | 64.4% |
| 3247549 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.79 | 58.0 | 5.55e-01 | 76.9% | 70.0% |
| 3411573 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.79 | 73.0 | 5.83e-01 | 100.0% | 53.7% |
| 5076088 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.78 | 58.0 | 5.60e-01 | 76.9% | 69.6% |
| 3335074 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.78 | 57.0 | 5.60e-01 | 75.2% | 76.2% |
| 3171851 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.78 | 59.0 | 5.30e-01 | 78.5% | 63.1% |
| 3478015 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.78 | 72.0 | 5.75e-01 | 100.0% | 54.6% |
| 3536637 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.77 | 58.0 | 5.52e-01 | 78.5% | 72.0% |
| 3868831 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.77 | 59.0 | 5.24e-01 | 78.5% | 62.4% |
| 3520105 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.77 | 58.0 | 5.34e-01 | 78.5% | 63.9% |
| 3908126 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 56.0 | 5.32e-01 | 76.9% | 72.1% |
| 3262083 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.75 | 56.0 | 5.95e-01 | 76.9% | 89.5% |
| 3442429 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 56.0 | 4.81e-01 | 76.9% | 52.4% |
| 4211332 | 633.10.1.35 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › NKAIN | 0.75 | 51.0 | 5.12e-01 | 76.9% | 69.2% |
| 3878975 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.75 | 57.0 | 5.40e-01 | 78.5% | 72.1% |
| 3245309 | 109.62.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain | 0.75 | 58.0 | 4.54e-01 | 81.0% | 47.9% |
| 4026224 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.74 | 63.0 | 4.76e-01 | 90.9% | 66.1% |
| 5051294 | 601.41.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein | 0.74 | 52.0 | 5.19e-01 | 78.5% | 70.4% |
| 3216366 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 55.0 | 4.89e-01 | 78.5% | 58.8% |
| 3739903 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 54.0 | 4.93e-01 | 78.5% | 59.4% |
| 3580347 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 52.0 | 5.55e-01 | 76.9% | 92.4% |
| 3201166 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.68 | 48.0 | 4.64e-01 | 72.7% | 80.7% |
| 3675860 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 49.0 | 4.29e-01 | 78.5% | 75.7% |
| 3808040 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 46.0 | 4.01e-01 | 71.9% | 84.2% |
| 3887920 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 48.0 | 4.45e-01 | 76.9% | 72.9% |
| 3724523 | 4121.1.1.7 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF26616 | 0.65 | 52.0 | 3.72e-01 | 86.0% | 61.9% |
| 4946565 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 47.0 | 4.77e-01 | 76.0% | 95.0% |
| 3176244 | 633.15.1.3 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › SOG2 | 0.64 | 57.0 | 5.21e-01 | 95.9% | 85.8% |
| 3716333 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.62 | 46.0 | 3.85e-01 | 77.7% | 89.8% |
| 3799907 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.61 | 57.0 | 5.55e-01 | 100.0% | 97.7% |
| 4497407 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.60 | 55.0 | 4.93e-01 | 99.2% | 89.7% |
| 3817153 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.57 | 43.0 | 4.58e-01 | 82.6% | 90.5% |
| 5026442 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.57 | 52.0 | 4.51e-01 | 100.0% | 79.2% |
| 3315159 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.57 | 51.0 | 4.67e-01 | 99.2% | 89.4% |
| 3377464 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.56 | 47.0 | 4.30e-01 | 93.4% | 68.1% |
| 3974204 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.54 | 47.0 | 4.81e-01 | 96.7% | 95.0% |
| 3436406 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.54 | 46.0 | 4.38e-01 | 90.1% | 93.6% |
| 3350358 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.51 | 43.0 | 4.19e-01 | 90.9% | 87.4% |