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pre4_saliva_scaffold_3_prodigal-single.1__X__X__00101
Bact-Virpre4_saliva_scaffold_3_prodigal-single.1__X__X__00101
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 11-118
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.76 | 58.0 | 5.78e-01 | 79.6% | 99.1% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.74 | 56.0 | 5.60e-01 | 78.7% | 100.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.72 | 52.0 | 5.12e-01 | 100.0% | 70.7% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.71 | 53.0 | 4.84e-01 | 78.7% | 69.5% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.68 | 49.0 | 4.01e-01 | 75.0% | 60.9% |
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.67 | 49.0 | 4.25e-01 | 82.4% | 50.9% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 53.0 | 4.43e-01 | 85.2% | 80.1% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.66 | 46.0 | 4.84e-01 | 75.0% | 78.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 5.10e-01 | 75.9% | 100.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.66 | 49.0 | 4.41e-01 | 99.1% | 57.1% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 52.0 | 4.36e-01 | 87.0% | 81.8% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.64 | 47.0 | 4.79e-01 | 99.1% | 77.8% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 45.0 | 4.10e-01 | 75.9% | 56.2% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 54.0 | 4.93e-01 | 99.1% | 96.6% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 44.0 | 4.56e-01 | 75.0% | 95.0% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 52.0 | 5.32e-01 | 100.0% | 96.2% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 4.31e-01 | 79.6% | 70.8% |
| 2x1lA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.60 | 48.0 | 4.19e-01 | 88.0% | 75.6% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.59 | 43.0 | 3.78e-01 | 100.0% | 50.3% |
| 2b7mA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.59 | 50.0 | 3.27e-01 | 95.4% | 42.5% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 49.0 | 4.99e-01 | 100.0% | 94.4% |
| 2nwbA02 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 51.0 | 3.97e-01 | 98.1% | 96.6% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.58 | 48.0 | 4.60e-01 | 93.5% | 83.7% |
| 3o60A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 49.0 | 4.24e-01 | 97.2% | 80.8% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 47.0 | 4.79e-01 | 88.9% | 98.1% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.57 | 43.0 | 3.50e-01 | 81.5% | 70.4% |
| 2h7oA01 | 1.20.120.1330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain | 0.56 | 48.0 | 4.64e-01 | 93.5% | 94.3% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 47.0 | 4.72e-01 | 100.0% | 92.6% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 50.0 | 4.88e-01 | 100.0% | 95.0% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 50.0 | 4.84e-01 | 100.0% | 87.7% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 49.0 | 4.74e-01 | 99.1% | 88.4% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 38.0 | 3.87e-01 | 92.6% | 74.5% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.55 | 46.0 | 4.07e-01 | 94.4% | 84.0% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 47.0 | 4.45e-01 | 100.0% | 78.7% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.54 | 46.0 | 4.50e-01 | 99.1% | 87.1% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 46.0 | 4.38e-01 | 93.5% | 89.8% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.53 | 47.0 | 4.43e-01 | 100.0% | 81.2% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 47.0 | 4.21e-01 | 97.2% | 95.3% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 40.0 | 3.78e-01 | 97.2% | 64.0% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.51 | 45.0 | 3.96e-01 | 100.0% | 66.1% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3206361 | 6108.1.1.0 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins | 0.68 | 47.0 | 3.87e-01 | 71.3% | 85.6% |
| 3758339 | 5086.1.1.65 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › USHBP1_PDZ-bd | 0.68 | 42.0 | 4.57e-01 | 77.8% | 74.4% |
| 3420616 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.67 | 52.0 | 4.05e-01 | 81.5% | 58.8% |
| 3407072 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 46.0 | 5.11e-01 | 97.2% | 97.5% |
| 3718312 | 604.1.1.118 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N | 0.66 | 49.0 | 4.49e-01 | 79.6% | 84.1% |
| 3272683 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 50.0 | 3.85e-01 | 84.3% | 89.6% |
| 3749996 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.64 | 48.0 | 4.57e-01 | 78.7% | 84.0% |
| 3812310 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.63 | 47.0 | 4.22e-01 | 99.1% | 56.1% |
| 3511834 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.62 | 46.0 | 4.38e-01 | 78.7% | 95.4% |
| 3887920 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 56.0 | 4.94e-01 | 100.0% | 76.8% |
| 3489528 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 51.0 | 4.54e-01 | 92.6% | 80.6% |
| 3824114 | 604.6.1.24 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF6857 | 0.61 | 45.0 | 4.24e-01 | 98.1% | 64.6% |
| 3272287 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.61 | 50.0 | 5.24e-01 | 97.2% | 97.0% |
| 3179977 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 51.0 | 3.35e-01 | 90.7% | 23.2% |
| 4459896 | 622.4.1.1 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 | 0.60 | 52.0 | 5.11e-01 | 100.0% | 89.5% |
| 4146380 | 4133.1.1.2 ↗ | alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 | 0.60 | 46.0 | 4.33e-01 | 81.5% | 73.8% |
| 3326943 | 109.4.1.891 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_HEATR1 | 0.59 | 46.0 | 3.37e-01 | 83.3% | 47.5% |
| 3770420 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 51.0 | 4.86e-01 | 100.0% | 83.2% |
| 3919843 | 604.1.1.124 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 | 0.58 | 52.0 | 4.96e-01 | 100.0% | 90.8% |
| 3428894 | 604.5.1.39 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF26581 | 0.58 | 53.0 | 4.86e-01 | 100.0% | 89.3% |
| 3276862 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.58 | 52.0 | 4.18e-01 | 100.0% | 75.3% |
| 3702176 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.57 | 51.0 | 4.72e-01 | 100.0% | 87.1% |
| 3934336 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 47.0 | 3.90e-01 | 88.9% | 61.6% |
| 3894879 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 48.0 | 4.93e-01 | 100.0% | 97.1% |
| 3723852 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 48.0 | 4.54e-01 | 100.0% | 76.3% |
| 3559718 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 48.0 | 4.83e-01 | 100.0% | 93.6% |
| 2325490 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 47.0 | 4.67e-01 | 100.0% | 89.3% |
| 3885014 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 49.0 | 4.75e-01 | 100.0% | 86.7% |
| 3461433 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.56 | 51.0 | 4.01e-01 | 100.0% | 64.1% |
| 3545240 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 48.0 | 4.74e-01 | 100.0% | 89.6% |
| 5057918 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.56 | 39.0 | 2.81e-01 | 71.3% | 52.8% |
| 5075208 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 46.0 | 3.36e-01 | 100.0% | 31.6% |
| 375971 | 633.21.1.1 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 | 0.56 | 38.0 | 3.92e-01 | 93.5% | 73.3% |
| 2651169 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 50.0 | 4.71e-01 | 100.0% | 83.8% |
| 3510684 | 109.4.1.1716 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like, MIF4G_like_2 | 0.55 | 45.0 | 2.99e-01 | 90.7% | 24.0% |
| 3695361 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 49.0 | 4.71e-01 | 100.0% | 87.2% |
| 3577232 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 48.0 | 4.66e-01 | 100.0% | 85.6% |
| 3659069 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.54 | 46.0 | 4.51e-01 | 93.5% | 99.2% |
| 3269956 | 1076.1.1.2 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Aph-1 | 0.54 | 49.0 | 3.84e-01 | 100.0% | 99.1% |
| 3626462 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 47.0 | 4.66e-01 | 99.1% | 97.4% |
| 3444544 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.53 | 45.0 | 4.08e-01 | 96.3% | 70.3% |
| 3532924 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.52 | 45.0 | 3.96e-01 | 100.0% | 70.0% |
| 3458159 | 192.29.1.54 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › BPS1 | 0.51 | 46.0 | 3.68e-01 | 100.0% | 51.2% |
| 3214913 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 44.0 | 3.81e-01 | 95.4% | 68.2% |
| 3780523 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.50 | 44.0 | 3.91e-01 | 100.0% | 72.5% |
D2
high
residues 121-244
Domain cluster:
rep: KT895374.1__ALN97878.1__Bp8pS_199__00199__D124-249
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mtxD00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.55 | 22.0 | 2.46e-01 | 97.6% | 44.2% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.53 | 24.0 | 3.07e-01 | 81.5% | 73.1% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.51 | 34.0 | 3.47e-01 | 100.0% | 68.5% |
| 3c2bA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 31.0 | 2.98e-01 | 83.1% | 51.0% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3510805 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 28.0 | 2.66e-01 | 100.0% | 35.9% |
| 3735768 | 5001.1.1.87 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS | 0.56 | 43.0 | 3.04e-01 | 82.3% | 43.7% |
| 3280380 | 1075.1.1.28 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › PF30402 | 0.51 | 41.0 | 3.28e-01 | 87.9% | 78.0% |