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proliferating_cell_nuclear_antigen

Euk-Vir

Anopheles_minimus_iridovirus

proliferating_cell_nuclear_antigen__YP_009021207__Anopheles_minimus_iridovirus__1465751

Identity

Accession:
YP_009021207 ↗
Protein ID:
proliferating_cell_nuclear_antigen
Kingdom:
euk

Quality

71.7 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Iridoviridae› Chloriridovirus› Chloriridovirus_anopheles1

TaxID: 1465751

Cluster

View cluster (140 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-71
PDB
Domain cluster: rep: IMGVR_UViG_2684622505_000002-2684622505-2684645343__D9-68
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3p91A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.84 78.0 5.12e-01 100.0% 26.9%
6j8yC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.84 76.0 4.98e-01 98.5% 27.5%
3a1jB00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.83 75.0 4.91e-01 100.0% 29.4%
1ud9A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.83 75.0 4.97e-01 100.0% 26.9%
2ix2B00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.82 74.0 4.93e-01 100.0% 26.5%
1t6lA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.79 68.0 4.53e-01 95.5% 26.9%
1vpkA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.75 69.0 5.53e-01 100.0% 60.8%
5agvA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.73 66.0 5.32e-01 100.0% 58.9%
6ptrB01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.73 66.0 5.47e-01 100.0% 65.5%
1p6pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.71 52.0 4.19e-01 77.3% 100.0%
1lfoA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.71 53.0 4.27e-01 80.3% 100.0%
1o8vA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.71 56.0 4.40e-01 84.8% 100.0%
5w7zA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.71 63.0 5.28e-01 100.0% 65.5%
3t0pA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.70 63.0 4.47e-01 100.0% 39.9%
4azpA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.70 56.0 4.41e-01 86.4% 100.0%
4rzkA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.69 51.0 4.69e-01 80.3% 79.3%
4i8oA02 3.30.160.690 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain 0.68 47.0 4.27e-01 72.7% 55.6%
4bfeA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 48.0 4.51e-01 75.8% 87.7%
2e9wB05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 46.0 4.17e-01 72.7% 93.4%
2fkcA01 3.40.1350.40 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.66 50.0 4.21e-01 80.3% 63.6%
2l33A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.66 45.0 4.09e-01 71.2% 62.6%
2v7sA00 3.30.2030.20 Alpha Beta › 2-Layer Sandwich › TBP-like › 0.66 45.0 3.37e-01 71.2% 29.6%
5kvsA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.66 49.0 3.65e-01 78.8% 33.3%
3u1wA01 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 52.0 3.76e-01 84.8% 44.3%
6efyA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 48.0 4.19e-01 77.3% 81.6%
1vyfA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.66 49.0 3.92e-01 80.3% 83.7%
1e8oD00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.65 46.0 4.43e-01 75.8% 71.1%
1bf3A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.64 45.0 3.12e-01 75.8% 87.9%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.63 45.0 4.46e-01 75.8% 74.6%
2pimA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.63 55.0 4.46e-01 100.0% 97.7%
3gdoA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.63 44.0 3.16e-01 74.2% 62.8%
3fssA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.62 45.0 4.19e-01 78.8% 80.2%
1xzwA01 2.60.40.380 Mainly Beta › Sandwich › Immunoglobulin-like › Purple acid phosphatase-like, N-terminal 0.62 46.0 4.06e-01 80.3% 86.7%
3i3lA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.62 44.0 2.70e-01 75.8% 77.4%
3besR01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 46.0 4.28e-01 80.3% 88.0%
7obmA01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.61 49.0 3.22e-01 92.4% 56.4%
3fcdB00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.61 43.0 3.61e-01 75.8% 45.4%
1ebdA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.61 50.0 4.15e-01 93.9% 95.9%
4fnvA02 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.60 52.0 3.43e-01 97.0% 83.3%
7ne4A01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.59 50.0 3.25e-01 97.0% 34.7%
1ohfA03 2.60.270.70 Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › 0.59 51.0 4.03e-01 98.5% 68.1%
3frnA01 3.10.129.70 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › 0.58 49.0 3.80e-01 92.4% 43.2%
4l2iB00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 49.0 3.30e-01 95.5% 51.3%
2m7oA00 3.10.450.400 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Uncharacterised protein PF15513, DUF4651 0.58 41.0 4.06e-01 75.8% 75.7%
1s2kA00 2.60.120.700 Mainly Beta › Sandwich › Jelly Rolls › Peptidase G1 0.58 50.0 3.62e-01 100.0% 56.8%
2ywqA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.58 49.0 4.52e-01 97.0% 79.5%
3rd7A00 2.40.160.210 Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain 0.58 48.0 3.27e-01 98.5% 35.6%
1c8uA02 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.57 50.0 4.18e-01 98.5% 85.2%
3i1aA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 40.0 3.54e-01 75.8% 52.4%
4ghnA02 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.57 42.0 3.65e-01 80.3% 95.2%
4gakA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.57 46.0 3.21e-01 95.5% 34.4%
3bbjA00 2.40.160.210 Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain 0.56 46.0 3.23e-01 100.0% 46.1%
3ovcA01 3.30.200.150 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › 0.56 39.0 3.89e-01 74.2% 80.3%
5yjlC02 3.20.180.10 Alpha Beta › Alpha-Beta Barrel › Split barrel-like › PNP-oxidase-like 0.56 45.0 3.85e-01 90.9% 61.3%
3nuhB03 3.10.20.690 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.55 42.0 3.79e-01 80.3% 64.0%
2gf6A00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.55 49.0 3.90e-01 100.0% 92.5%
2r41A00 3.10.450.150 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › enterococcus faecalis protein 0.55 45.0 4.06e-01 100.0% 65.0%
3zl8A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.55 37.0 2.63e-01 71.2% 71.7%
1xa6A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.53 44.0 3.82e-01 92.4% 66.3%
1wv4B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.52 45.0 3.42e-01 95.5% 74.0%
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 36.0 3.74e-01 74.2% 84.1%
2ci8A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.52 40.0 4.33e-01 95.5% 98.2%
2gsbA01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.52 42.0 3.95e-01 98.5% 71.4%
2eqmA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.52 35.0 3.74e-01 87.9% 86.8%
2lc4A00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.52 42.0 3.63e-01 93.9% 90.1%
8enbA01 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.52 37.0 3.48e-01 77.3% 89.2%
5bncA02 3.20.180.10 Alpha Beta › Alpha-Beta Barrel › Split barrel-like › PNP-oxidase-like 0.51 41.0 3.72e-01 90.9% 68.8%
3lbfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 46.0 3.21e-01 98.5% 63.8%
4nhxA02 2.60.120.620 Mainly Beta › Sandwich › Jelly Rolls › q2cbj1_9rhob like domain 0.50 37.0 2.66e-01 83.3% 83.4%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5056758 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.84 72.0 5.88e-01 92.4% 68.7%
3997015 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.83 72.0 5.69e-01 93.9% 66.9%
3932751 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.83 71.0 5.61e-01 93.9% 53.8%
5023031 227.1.1.1 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_N 0.82 74.0 5.92e-01 98.5% 52.8%
3624708 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.81 71.0 5.61e-01 97.0% 65.9%
4212381 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 73.0 5.70e-01 98.5% 65.9%
3230925 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.81 72.0 5.68e-01 97.0% 68.5%
5028024 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 72.0 5.73e-01 98.5% 66.2%
5051689 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.80 70.0 5.65e-01 97.0% 68.8%
5029787 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 5.80e-01 100.0% 69.2%
3789625 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.78 64.0 4.99e-01 87.9% 45.2%
3244229 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.78 68.0 5.47e-01 95.5% 68.0%
3625037 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.78 63.0 4.95e-01 87.9% 44.4%
1387073 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.77 68.0 6.05e-01 97.0% 96.7%
1924009 227.1.1.10 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Herpes_PAP 0.74 66.0 5.23e-01 100.0% 66.2%
3721374 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.74 57.0 4.89e-01 81.8% 77.0%
3596476 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.73 62.0 4.82e-01 95.5% 70.6%
3405797 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.72 51.0 4.52e-01 74.2% 80.0%
3507499 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.71 61.0 4.82e-01 95.5% 71.1%
4614038 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.70 56.0 4.36e-01 84.8% 100.0%
3436239 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.70 51.0 3.07e-01 77.3% 17.4%
3780776 211.1.1.1 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.69 46.0 3.51e-01 71.2% 31.0%
3713027 319.1.1.3 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.68 47.0 3.86e-01 74.2% 58.4%
4958282 12.3.1.14 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Hepar_II_III 0.67 47.0 2.97e-01 74.2% 64.0%
2755883 331.19.1.1 ↗ a+b two layers › TBP-like › Toxin RnlA N-terminal domains › Toxin RnlA N-terminal domains › RnlA_toxin 0.67 46.0 4.17e-01 72.7% 54.3%
4991274 218.4.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Dhaf4260 N-terminal domain › Dhaf4260 N-terminal domain › DUF4213 0.67 47.0 4.16e-01 74.2% 54.7%
3623534 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.67 47.0 4.31e-01 75.8% 81.1%
3598260 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.66 53.0 4.33e-01 87.9% 48.0%
5014688 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.66 44.0 4.74e-01 74.2% 83.6%
4014375 3256.1.1.0 ↗ a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain 0.65 45.0 5.03e-01 72.7% 96.0%
4985279 319.1.1.4 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › ArsA_HSP20 0.65 46.0 4.42e-01 81.8% 63.7%
4668044 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.64 48.0 3.84e-01 80.3% 50.4%
4941640 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.64 44.0 3.40e-01 75.8% 31.0%
5005811 3414.1.1.0 ↗ beta sandwiches › A putative surface protein › A putative surface protein › A putative surface protein 0.63 46.0 4.35e-01 84.8% 63.7%
5004981 3335.1.1.0 ↗ beta barrels › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B 0.63 45.0 4.56e-01 74.2% 100.0%
3787121 241.15.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.63 47.0 3.92e-01 83.3% 76.8%
4990115 318.1.1.0 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.62 45.0 4.05e-01 75.8% 63.3%
4116346 3675.1.1.0 ↗ a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain 0.62 42.0 3.22e-01 71.2% 51.2%
3408937 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.62 43.0 4.06e-01 72.7% 62.5%
3993098 5.1.5.52 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › EMC1_C 0.62 52.0 3.05e-01 95.5% 18.3%
4215371 318.1.1.1 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.61 45.0 4.06e-01 77.3% 64.4%
3936023 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.61 54.0 3.49e-01 100.0% 40.0%
4544568 719.1.1.5 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › PF27933 0.61 51.0 4.46e-01 100.0% 98.2%
5074419 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.61 41.0 4.19e-01 75.8% 70.8%
4011809 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.61 44.0 2.72e-01 77.3% 13.6%
4355722 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.61 48.0 4.25e-01 84.8% 89.5%
3170723 220.1.1.95 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › VID27_PH 0.60 44.0 3.76e-01 80.3% 75.7%
4018808 719.1.1.0 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain 0.60 49.0 4.21e-01 100.0% 96.7%
5002092 283.2.1.0 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.60 47.0 4.23e-01 84.8% 64.4%
4955327 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 40.0 4.32e-01 95.5% 85.5%
3959969 3270.1.1.1 ↗ a+b two layers › a+b domain in heme oxygenase › a+b domain in heme oxygenase › a+b domain in heme oxygenase › DUF2470 0.59 48.0 4.38e-01 90.9% 73.3%
3954845 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.59 40.0 2.58e-01 71.2% 15.8%
3825119 3270.1.1.0 ↗ a+b two layers › a+b domain in heme oxygenase › a+b domain in heme oxygenase › a+b domain in heme oxygenase 0.59 48.0 4.35e-01 100.0% 66.7%
4153542 2003.1.2.16 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3,NAD_binding_8 0.58 42.0 2.62e-01 77.3% 80.7%
4941490 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.57 43.0 3.40e-01 80.3% 65.2%
3267754 719.1.1.2 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF 0.57 48.0 4.01e-01 98.5% 92.0%
3837990 3675.1.1.0 ↗ a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain 0.57 38.0 3.08e-01 74.2% 35.4%
3940470 5.1.4.320 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_LRRK2 0.56 48.0 3.00e-01 97.0% 31.9%
5053281 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 38.0 3.22e-01 72.7% 99.2%
3967250 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.56 45.0 2.86e-01 89.4% 16.9%
3943777 7520.1.1.0 ↗ a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like 0.56 51.0 3.91e-01 100.0% 55.9%
5044385 101.1.2.136 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.56 38.0 2.75e-01 74.2% 22.9%
3700578 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.55 39.0 4.08e-01 78.8% 81.7%
327025 6048.1.1.1 ↗ a+b two layers › DUF960-like › DUF960-like › DUF960-like › DUF960 0.55 46.0 4.04e-01 100.0% 63.2%
3812366 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.55 39.0 2.81e-01 77.3% 47.4%
3588565 6048.1.1.1 ↗ a+b two layers › DUF960-like › DUF960-like › DUF960-like › DUF960 0.54 47.0 4.32e-01 100.0% 73.9%
3277345 7512.1.1.4 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_10 0.54 46.0 2.86e-01 98.5% 24.7%
4059727 7502.1.1.0 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.54 44.0 3.35e-01 92.4% 50.3%
4011254 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.53 47.0 3.04e-01 100.0% 75.2%
4413343 2003.6.1.5 ↗ a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › Phos_pyr_kin 0.53 48.0 3.14e-01 100.0% 37.4%
3337354 719.1.1.0 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain 0.53 41.0 3.49e-01 93.9% 88.5%
3507003 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 38.0 3.66e-01 78.8% 84.0%
4975478 4.1.1.40 ↗ beta barrels › SH3 › SH3 › SH3 › FeoA 0.52 44.0 4.12e-01 98.5% 91.8%
3690077 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.52 47.0 3.07e-01 100.0% 75.1%
3592742 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.51 39.0 3.63e-01 89.4% 95.6%
D2 high residues 85-202
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u7bA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.81 72.0 5.46e-01 93.2% 45.8%
1sxjH02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.81 71.0 6.96e-01 93.2% 92.2%
1ud9A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.81 72.0 5.55e-01 94.1% 47.1%
1plqA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.80 73.0 5.50e-01 95.8% 46.9%
2ix2B00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.80 72.0 5.50e-01 94.1% 46.5%
3p91A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.80 71.0 5.43e-01 93.2% 44.9%
6j8yC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.79 69.0 5.25e-01 92.4% 46.7%
3ifvC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.79 69.0 5.34e-01 92.4% 47.1%
1sxjH01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.77 67.0 6.63e-01 93.2% 94.4%
1rwzA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.77 67.0 5.23e-01 94.1% 46.3%
3a1jB00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.76 66.0 4.97e-01 93.2% 48.7%
5agvA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.74 66.0 6.33e-01 94.1% 91.6%
3t0pA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.74 64.0 5.35e-01 95.8% 56.5%
1vpkA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.73 63.0 6.35e-01 93.2% 90.8%
2avtA02 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.73 65.0 5.40e-01 95.8% 57.3%
4trtA03 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.72 63.0 6.28e-01 93.2% 93.3%
5w7zA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.71 61.0 6.28e-01 93.2% 96.5%
5wceA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.70 61.0 5.98e-01 94.1% 90.7%
3pweA01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.70 61.0 6.01e-01 93.2% 89.4%
4i8oA01 3.30.310.240 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Bacterial toxin RNase RnlA/LsoA, N-terminal domain 0.61 32.0 3.58e-01 83.9% 64.0%
2r41A00 3.10.450.150 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › enterococcus faecalis protein 0.60 40.0 4.31e-01 95.8% 78.6%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.59 33.0 4.04e-01 89.0% 88.7%
3hi0A02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.58 31.0 2.66e-01 72.9% 32.8%
3doaA01 2.30.310.10 Mainly Beta › Roll › ibrinogen binding protein from staphylococcus aureus fold › ibrinogen binding protein from staphylococcus aureus domain 0.57 44.0 4.09e-01 82.2% 98.7%
2qmiA02 2.40.128.210 Mainly Beta › Beta Barrel › Lipocalin › Pab87 octamerisation domain 0.56 35.0 3.76e-01 79.7% 73.0%
3ossC00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.54 30.0 3.75e-01 83.1% 95.4%
1uebA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 28.0 3.65e-01 79.7% 93.7%
3d3rA00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.51 28.0 3.22e-01 74.6% 72.3%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030418 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.83 73.0 6.82e-01 92.4% 90.7%
4026069 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.83 73.0 6.92e-01 92.4% 88.1%
4025727 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.82 71.0 6.70e-01 91.5% 87.1%
2805173 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.82 72.0 7.11e-01 94.1% 91.2%
4936050 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 72.0 7.05e-01 93.2% 92.0%
138072 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 72.0 6.93e-01 93.2% 90.1%
1290662 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 72.0 6.66e-01 93.2% 83.2%
3997015 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.81 70.0 6.78e-01 91.5% 89.2%
4013292 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.81 71.0 6.78e-01 93.2% 90.4%
167574 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.81 72.0 6.95e-01 94.1% 87.0%
4372908 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.81 71.0 6.94e-01 93.2% 87.2%
3738030 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.81 70.0 6.67e-01 92.4% 88.9%
2392831 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.80 71.0 6.89e-01 93.2% 90.6%
143428 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.80 71.0 7.06e-01 93.2% 91.7%
3551142 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.80 70.0 6.50e-01 93.2% 82.8%
3230925 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.80 72.0 6.97e-01 95.8% 91.5%
4055466 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.80 72.0 7.12e-01 95.8% 93.5%
5010672 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.80 72.0 7.21e-01 95.8% 95.8%
3292092 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.80 72.0 6.85e-01 95.8% 92.5%
3624708 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.79 71.0 6.79e-01 95.8% 88.9%
4948360 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 69.0 6.72e-01 92.4% 86.8%
3932751 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.79 68.0 6.59e-01 91.5% 90.0%
4646871 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 7.00e-01 95.8% 92.0%
4976500 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 6.94e-01 95.8% 90.6%
3407530 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.79 68.0 6.54e-01 92.4% 88.9%
4456195 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.79 71.0 7.14e-01 95.8% 95.0%
4956740 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 6.98e-01 95.8% 93.6%
3782606 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.79 69.0 6.46e-01 94.1% 86.9%
309454 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.79 71.0 6.84e-01 95.8% 87.1%
4517015 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 7.00e-01 95.8% 92.7%
4995028 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 6.95e-01 95.8% 96.0%
4941929 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 71.0 6.91e-01 95.8% 90.6%
3734891 227.1.1.4 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad1 0.79 68.0 6.27e-01 92.4% 92.0%
4232371 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.79 71.0 7.06e-01 95.8% 95.8%
5037345 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.79 70.0 6.77e-01 95.8% 91.0%
5037314 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.79 68.0 6.76e-01 91.5% 93.3%
5000468 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.78 70.0 6.90e-01 95.8% 95.2%
3936914 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.78 70.0 6.82e-01 95.8% 91.5%
4660283 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.78 70.0 6.85e-01 95.8% 93.6%
5052551 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.78 69.0 6.82e-01 95.8% 92.0%
3719897 227.1.1.18 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DUF7881_C 0.77 65.0 6.42e-01 89.8% 88.8%
3256904 227.1.1.12 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad9 0.77 67.0 6.61e-01 93.2% 95.2%
5991 227.1.1.6 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_C 0.77 67.0 6.69e-01 94.1% 92.6%
3743106 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.77 66.0 6.15e-01 92.4% 92.4%
4360456 227.1.1.8 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_3 0.75 66.0 6.37e-01 94.1% 87.7%
4460660 227.1.1.7 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_2 0.75 66.0 6.31e-01 94.1% 88.9%
3625037 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.75 64.0 6.15e-01 92.4% 92.6%
3789625 227.1.1.0 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.74 64.0 6.13e-01 92.4% 92.6%
3022412 227.1.1.11 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.74 65.0 6.07e-01 94.1% 88.0%
4162061 227.1.1.8 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_3 0.74 64.0 6.35e-01 93.2% 91.9%
4542774 227.1.1.8 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_3 0.72 62.0 6.22e-01 92.4% 92.5%
3387590 227.1.1.8 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_3 0.72 60.0 6.11e-01 95.8% 91.3%
3015240 227.1.1.7 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_2 0.72 63.0 6.30e-01 94.1% 91.0%
4591776 227.1.1.7 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_2 0.72 63.0 6.09e-01 94.1% 87.7%
2878147 227.1.1.8 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta_3 0.71 65.0 6.20e-01 100.0% 89.1%
4047098 227.1.1.3 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_pol3_beta 0.69 60.0 6.00e-01 93.2% 93.3%
3882163 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 42.0 3.26e-01 72.0% 55.7%
3588565 6048.1.1.1 ↗ a+b two layers › DUF960-like › DUF960-like › DUF960-like › DUF960 0.56 38.0 4.31e-01 95.8% 93.2%
4946166 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.52 27.0 3.52e-01 80.5% 96.7%
4284803 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.52 29.0 2.86e-01 86.4% 49.6%
4464688 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.51 27.0 2.95e-01 82.2% 61.7%
5035423 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.50 30.0 3.55e-01 88.1% 83.5%