protease-helicase_NS3

Euk-Vir

Hepacivirus_B

protease-helicase_NS3__YP_009678989__Hepacivirus_B__2008762

Identity

83.5 mean pLDDT

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Hepacivirus› Hepacivirus_platyrrhini

TaxID: 2008762

View cluster (30 members)

Download PDB Download Scores JSON

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-170

PDB

Domain cluster: rep: 100_kDa_protein__YP_008130303__Citrus_vein_enation_virus__1301220__D379-571

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02907.22 best	Peptidase_S29	200.9	1.20e-59	83.9%	94.0%

D2 high residues 187-320

PDB

Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D53-65_81-193

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07652.21 best	Flavi_DEAD	21.4	2.90e-04	94.0%	68.9%

D3 high residues 334-472

PDB

Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425

D4 medium residues 525-619

PDB

Domain cluster: rep: putative_NS3_protein__YP_009256194_putative_NS3_protein__GB_virus-D__2847088__D538-619

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1a1vA03	1.10.820.10	Mainly Alpha › Orthogonal Bundle › RNA Helicase; Chain A, domain 3 › RNA Helicase Chain A , domain 3	0.89	81.0	6.65e-01	96.8%	60.2%
3e0fA02	1.10.150.650	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.51	36.0	3.93e-01	94.7%	95.9%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1233818	5101.1.1.2 ↗	alpha arrays › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › C-terminal helical domain of RNA helicase › NS3_helicase_C	0.88	83.0	7.00e-01	100.0%	67.1%
3206943	70.3.1.0 ↗	beta barrels › beta-clip › SET domain-like › SET domain-like	0.55	45.0	3.29e-01	90.5%	70.4%