←Back to structures
protease_2A
Euk-VirDromedary_camel_enterovirus_19CC
protease_2A__YP_009508967__Dromedary_camel_enterovirus_19CC__1637527
Identity
- Accession:
- YP_009508967 ↗
- Protein ID:
- protease_2A
- Kingdom:
- euk
Quality
90.6
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Picornavirales›
Picornaviridae›
Enterovirus›
Dromedary_camel_enterovirus_19CC
TaxID: 1637527
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 60-136
Domain cluster:
rep: hypothetical_protein_1__YP_009336741__Shahe_picorna-like_virus_12__1923442__D757-836
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00947.26 best | Pico_P2A | 134.6 | 3.00e-39 | 100.0% | 60.6% |
D2
medium
residues 1-50
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00947.26 best | Pico_P2A | 33.0 | 7.90e-08 | 64.0% | 25.2% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z8rA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.96 | 76.0 | 8.31e-01 | 84.0% | 100.0% |
| 2hrvA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.86 | 71.0 | 7.52e-01 | 90.0% | 100.0% |
| 5hmaA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.78 | 70.0 | 5.79e-01 | 100.0% | 95.4% |
| 3nziA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.77 | 68.0 | 5.32e-01 | 100.0% | 82.1% |
| 4ic6C01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.77 | 68.0 | 5.26e-01 | 100.0% | 85.5% |
| 4yo1A01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.77 | 68.0 | 5.60e-01 | 100.0% | 91.0% |
| 1lvmA02 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.74 | 61.0 | 4.82e-01 | 92.0% | 73.6% |
| 3szeA01 | 2.40.10.120 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.72 | 62.0 | 3.81e-01 | 100.0% | 31.8% |
| 1orfA02 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.72 | 60.0 | 4.73e-01 | 94.0% | 86.7% |
| 2hlcA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.72 | 59.0 | 4.65e-01 | 92.0% | 86.5% |
| 2o8mB01 | 2.40.10.120 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.71 | 59.0 | 5.45e-01 | 94.0% | 92.4% |
| 4f4oC03 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.71 | 58.0 | 4.83e-01 | 92.0% | 100.0% |
| 1shyA02 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.70 | 58.0 | 4.64e-01 | 94.0% | 89.2% |
| 3su0A01 | 2.40.10.120 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.70 | 60.0 | 4.72e-01 | 100.0% | 81.2% |
| 1r6vA02 | 3.30.70.80 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 | 0.70 | 55.0 | 4.81e-01 | 88.0% | 73.1% |
| 1dleA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.70 | 60.0 | 4.52e-01 | 100.0% | 79.8% |
| 7u5bJ01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.67 | 55.0 | 4.77e-01 | 92.0% | 87.2% |
| 3dxqA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.67 | 54.0 | 4.61e-01 | 90.0% | 74.7% |
| 3kmaA00 | 2.170.270.10 | Mainly Beta › Beta Complex › Beta-clip-like › SET domain | 0.64 | 41.0 | 3.27e-01 | 72.0% | 30.5% |
| 1avaA02 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.63 | 49.0 | 4.70e-01 | 86.0% | 87.9% |
| 2vz6B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 50.0 | 4.28e-01 | 90.0% | 86.7% |
| 2wb6A00 | 3.90.1150.90 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › | 0.58 | 46.0 | 3.63e-01 | 90.0% | 64.9% |
| 3wrwA02 | 3.40.50.12030 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Uncharacterised protein family UPF0261, NC domain | 0.58 | 47.0 | 3.20e-01 | 98.0% | 45.9% |
| 1rkqA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.57 | 41.0 | 3.37e-01 | 82.0% | 89.7% |
| 6ll8A02 | 3.10.310.20 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain | 0.57 | 46.0 | 3.59e-01 | 96.0% | 78.3% |
| 7y6oA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 42.0 | 3.57e-01 | 82.0% | 98.9% |
| 4ab7H02 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.57 | 45.0 | 3.28e-01 | 92.0% | 59.2% |
| 5eh1A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 44.0 | 3.64e-01 | 88.0% | 96.8% |
| 6swc801 | 3.30.30.170 | Alpha Beta › 2-Layer Sandwich › Defensin A-like › | 0.56 | 41.0 | 3.27e-01 | 82.0% | 47.4% |
| 3ll3B02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 41.0 | 2.73e-01 | 90.0% | 60.0% |
| 2kkqA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 39.0 | 3.16e-01 | 84.0% | 74.1% |
| 6g80B01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 41.0 | 2.88e-01 | 100.0% | 38.9% |
| 2co5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 36.0 | 3.21e-01 | 84.0% | 76.1% |
| 2iepA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 37.0 | 3.18e-01 | 86.0% | 89.6% |
| 5erdB05 | 2.60.40.60 | Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins | 0.51 | 37.0 | 3.27e-01 | 90.0% | 95.7% |
| 2j8hA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 37.0 | 3.17e-01 | 86.0% | 92.8% |
| 4brcA02 | 3.30.420.150 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 | 0.50 | 37.0 | 2.56e-01 | 88.0% | 85.5% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4882551 | 1.1.5.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pico_P2A | 0.97 | 84.0 | 5.67e-01 | 90.0% | 30.2% |
| 1096951 | 1.1.5.13 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S6 | 0.72 | 62.0 | 3.94e-01 | 100.0% | 38.0% |
| 3608730 | 601.23.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III | 0.63 | 53.0 | 3.27e-01 | 98.0% | 20.9% |
| 3715575 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.62 | 49.0 | 3.95e-01 | 86.0% | 55.8% |
| 3316007 | 12.1.1.5 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amyl_C2 | 0.62 | 47.0 | 4.81e-01 | 84.0% | 100.0% |
| 5029311 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.61 | 51.0 | 3.77e-01 | 96.0% | 60.7% |
| 4927584 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.61 | 42.0 | 4.13e-01 | 74.0% | 100.0% |
| 4934123 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.60 | 43.0 | 4.07e-01 | 76.0% | 93.3% |
| 4454397 | 2007.1.17.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Resistance protein Tm-1 second domain › UPF0261_C | 0.60 | 49.0 | 3.30e-01 | 98.0% | 43.1% |
| 3656217 | 601.23.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III | 0.59 | 47.0 | 2.86e-01 | 92.0% | 17.8% |
| 5048372 | 242.2.1.2 ↗ | a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N | 0.58 | 44.0 | 3.96e-01 | 88.0% | 92.0% |
| 3502649 | 3012.1.1.4 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Hydrolase_3 | 0.58 | 42.0 | 3.39e-01 | 82.0% | 87.3% |
| 4985396 | 213.1.1.27 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_7 | 0.56 | 45.0 | 3.67e-01 | 92.0% | 97.0% |
| 3487240 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.55 | 44.0 | 3.25e-01 | 100.0% | 65.9% |
| 5025384 | 304.165.1.1 ↗ | a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › Ta1207 | 0.55 | 44.0 | 3.33e-01 | 100.0% | 60.8% |
| 3266596 | 11.1.1.29 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › TIG | 0.55 | 42.0 | 3.54e-01 | 86.0% | 92.2% |
| 4024871 | 325.1.8.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Ribosomal L27 protein | 0.54 | 42.0 | 3.88e-01 | 86.0% | 69.2% |
| 5059895 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 39.0 | 3.34e-01 | 88.0% | 91.0% |
| 3491392 | 389.3.1.1 ↗ | few secondary structure elements › EGF-like › LDL receptor-like module › LDL receptor-like module › Ldl_recept_a | 0.53 | 39.0 | 2.46e-01 | 86.0% | 24.9% |
| 4991995 | 3696.1.1.2 ↗ | a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD | 0.53 | 39.0 | 3.74e-01 | 88.0% | 93.8% |
| 3911452 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.52 | 38.0 | 3.08e-01 | 88.0% | 72.5% |
| 4643746 | 12.1.1.5 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amyl_C2 | 0.51 | 39.0 | 3.63e-01 | 92.0% | 87.1% |
| 3345563 | 3364.1.1.0 ↗ | few secondary structure elements › Epidermal patterning factor-like protein 9 › Epidermal patterning factor-like protein 9 › Epidermal patterning factor-like protein 9 | 0.51 | 36.0 | 3.52e-01 | 80.0% | 73.3% |
| 1149979 | 2484.1.1.15 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › GDA1_CD39 | 0.50 | 38.0 | 2.61e-01 | 88.0% | 89.0% |
| 3919818 | 11.1.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Cadherin | 0.50 | 36.0 | 3.04e-01 | 88.0% | 83.5% |