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protease

Euk-Vir

Simian_adenovirus_49

protease__YP_004300214__Simian_adenovirus_49__995022

Identity

Accession:
YP_004300214 ↗
Protein ID:
protease
Kingdom:
euk

Quality

87.5 mean pLDDT

Taxonomy

Bamfordvirae› Preplasmiviricota› Pharingeaviricetes› Rowavirales› Adenoviridae› Mastadenovirus› Simian_adenovirus_49

TaxID: 995022

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-112
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00770.25 best Peptidase_C5 150.0 8.40e-44 82.1% 50.8%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ekfA00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.88 75.0 6.12e-01 100.0% 52.1%
1xt9A00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.74 69.0 5.49e-01 100.0% 61.5%
1th0B00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.70 65.0 5.07e-01 100.0% 57.4%
1euvA02 3.30.310.130 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Ubiquitin-related 0.68 54.0 5.59e-01 84.8% 100.0%
3nroA00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.65 44.0 3.45e-01 70.5% 83.4%
2bh1X00 3.30.300.160 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Type II secretion system, protein E, N-terminal domain 0.64 33.0 4.04e-01 73.2% 79.4%
2k5tA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.59 46.0 4.44e-01 96.4% 72.7%
1ib8A01 3.30.300.70 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › RimP-like superfamily, N-terminal 0.58 40.0 4.51e-01 70.5% 100.0%
2l72A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.58 43.0 4.23e-01 77.7% 89.0%
5h8yD02 3.30.413.10 Alpha Beta › 2-Layer Sandwich › Sulfite Reductase Hemoprotein; domain 1 › Sulfite Reductase Hemoprotein, domain 1 0.58 41.0 3.43e-01 75.0% 89.7%
3pe5A00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.57 47.0 3.50e-01 88.4% 81.9%
3gkuC02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.57 40.0 4.34e-01 83.9% 91.0%
2xxpA02 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.55 47.0 3.57e-01 92.9% 83.3%
2xswB00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.55 48.0 3.54e-01 100.0% 71.5%
3owcB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 50.0 4.32e-01 100.0% 65.3%
1ufhA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 49.0 4.39e-01 97.3% 79.4%
1m2oA05 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.54 42.0 4.30e-01 83.0% 87.6%
1cm0A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 43.0 3.87e-01 98.2% 61.1%
1d0nA03 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.53 39.0 3.88e-01 83.9% 71.9%
2nutB05 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.52 41.0 3.95e-01 83.0% 89.1%
6uf3A00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.52 40.0 3.15e-01 83.9% 92.1%
3mf1B00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 44.0 3.45e-01 98.2% 77.8%
1hc7A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.51 43.0 3.40e-01 97.3% 77.0%
3thxA02 3.30.420.110 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain 0.51 40.0 3.56e-01 83.9% 100.0%
2p18A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.51 45.0 3.40e-01 98.2% 47.0%
2o8bB02 3.30.420.110 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain 0.51 39.0 3.34e-01 83.0% 93.0%
3okzB00 3.40.630.190 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein 0.50 42.0 3.16e-01 92.9% 81.0%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
153044 219.1.1.5 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C5 0.88 75.0 6.12e-01 100.0% 52.1%
3788927 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 68.0 5.18e-01 100.0% 56.9%
3698900 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 68.0 4.91e-01 100.0% 53.9%
3994259 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 68.0 5.21e-01 100.0% 54.9%
3723740 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.73 68.0 5.12e-01 100.0% 65.6%
2410593 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.72 66.0 4.96e-01 100.0% 64.4%
3462610 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.72 66.0 5.18e-01 100.0% 60.0%
3498187 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.72 67.0 5.13e-01 100.0% 57.0%
3444042 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.72 67.0 5.43e-01 100.0% 74.7%
3677902 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 65.0 4.06e-01 100.0% 26.4%
3189169 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 65.0 5.13e-01 100.0% 58.9%
3209165 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.70 65.0 4.99e-01 100.0% 55.5%
3410176 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.70 64.0 5.14e-01 100.0% 57.2%
4026880 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.70 65.0 4.97e-01 100.0% 60.8%
3738382 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.70 64.0 4.93e-01 100.0% 54.6%
3627887 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.69 63.0 5.37e-01 100.0% 66.1%
3793128 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.69 63.0 5.29e-01 100.0% 63.8%
3416006 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.69 64.0 4.97e-01 100.0% 57.4%
None — 0.69 63.0 5.05e-01 100.0% 57.2%
3681708 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.69 63.0 4.12e-01 100.0% 32.3%
3776113 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.68 63.0 4.75e-01 100.0% 47.3%
3635663 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.68 63.0 4.75e-01 100.0% 53.8%
3256272 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.68 63.0 4.88e-01 100.0% 59.8%
3466516 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.68 63.0 4.85e-01 100.0% 54.2%
3216657 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.68 62.0 5.10e-01 100.0% 59.0%
3369707 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.67 62.0 4.56e-01 100.0% 48.8%
3458803 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.67 62.0 4.98e-01 100.0% 72.4%
3459162 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.67 61.0 4.60e-01 100.0% 56.3%
3660659 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.66 61.0 4.62e-01 100.0% 44.4%
3696004 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.66 59.0 4.67e-01 100.0% 56.2%
3826010 219.1.1.16 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.65 59.0 4.44e-01 100.0% 61.1%
3249372 224.1.1.2 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.64 44.0 4.52e-01 71.4% 82.7%
3645871 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.64 59.0 4.04e-01 100.0% 42.4%
5051316 224.1.1.0 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.62 43.0 4.44e-01 70.5% 85.7%
4302422 213.1.1.6 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › ODC_AZ 0.62 47.0 4.29e-01 92.9% 61.8%
3644493 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.60 56.0 3.74e-01 100.0% 29.5%
3511219 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 41.0 3.62e-01 70.5% 99.4%
4401040 213.1.1.27 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_7 0.60 39.0 4.25e-01 84.8% 81.1%
4218309 224.1.1.2 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.59 42.0 2.66e-01 75.0% 16.3%
4615831 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.59 41.0 3.66e-01 72.3% 95.2%
4998669 224.1.1.0 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.59 40.0 4.18e-01 70.5% 76.2%
4997461 224.1.1.2 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.58 40.0 4.42e-01 83.9% 88.8%
3963258 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.58 40.0 3.67e-01 72.3% 94.8%
5072973 224.1.1.0 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.57 41.0 4.23e-01 83.0% 79.0%
4995984 224.1.1.0 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.57 38.0 4.18e-01 82.1% 85.6%
3877607 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.56 38.0 3.19e-01 70.5% 94.6%
4997307 224.1.1.2 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.56 38.0 4.02e-01 83.9% 78.0%
3784292 247.1.1.0 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.55 49.0 3.72e-01 99.1% 64.8%
3873014 246.3.1.4 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos2 0.55 48.0 3.44e-01 100.0% 68.2%
1149513 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.55 39.0 3.61e-01 74.1% 83.7%
5063947 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.54 47.0 4.15e-01 97.3% 65.6%
3801169 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 34.0 2.48e-01 100.0% 21.9%
4048529 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.54 38.0 3.37e-01 72.3% 92.1%
3242747 7579.1.1.14 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_3 0.51 42.0 3.10e-01 91.1% 46.6%
4680522 327.10.1.2 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA 0.50 38.0 3.89e-01 85.7% 84.8%
3709411 247.1.1.1 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.50 45.0 3.19e-01 100.0% 54.3%
D2 medium residues 113-199
PDB
Domain cluster: rep: protease__YP_009362849__Bat_mastadenovirus_WIV17__1986505__D137-198
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00770.25 best Peptidase_C5 117.3 8.80e-34 100.0% 48.0%