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protein_3CD

Euk-Vir

Enterovirus_C

protein_3CD__YP_007353734__Enterovirus_C__138950

Identity

Accession:
YP_007353734 ↗
Protein ID:
protein_3CD
Kingdom:
euk

Quality

91.8 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Picornavirales› Picornaviridae› Enterovirus› Enterovirus_C

TaxID: 138950

Cluster

View cluster (450 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-154
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00548.27 best Peptidase_C3 212.8 4.30e-63 100.0% 91.6%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ijd101 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.99 98.0 9.10e-01 100.0% 85.0%
3otpA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.78 73.0 6.57e-01 100.0% 77.3%
1wxrA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.71 67.0 5.49e-01 100.0% 66.5%
2xrcC04 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.67 59.0 5.60e-01 93.5% 79.8%
2xs2A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 31.0 3.97e-01 79.7% 86.2%
3smzA03 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 29.0 3.65e-01 77.8% 78.4%
4qu7A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 28.0 3.78e-01 77.8% 88.9%
5uznA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 28.0 3.79e-01 77.8% 90.0%
3sdeA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.55 29.0 3.66e-01 77.1% 85.4%
7oc3A01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.53 30.0 3.64e-01 98.7% 87.0%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2779726 1.1.17.2 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_C3 0.99 97.0 8.92e-01 100.0% 82.3%
376155 1.1.17.2 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_C3 0.87 83.0 7.52e-01 100.0% 83.7%
3066474 1.1.17.2 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_C3 0.87 83.0 7.34e-01 100.0% 81.2%
5072499 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.82 77.0 6.97e-01 100.0% 78.0%
4683578 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.81 75.0 6.50e-01 98.7% 81.8%
4338510 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.79 75.0 6.56e-01 100.0% 74.0%
4221728 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.78 72.0 6.20e-01 98.7% 69.6%
4329871 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.78 73.0 6.71e-01 100.0% 80.0%
3933067 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.77 72.0 5.77e-01 100.0% 77.9%
4587424 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.76 69.0 6.06e-01 96.7% 80.9%
3408679 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.76 69.0 5.91e-01 96.7% 79.4%
3106034 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.75 71.0 5.95e-01 98.7% 72.4%
3752007 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 67.0 5.72e-01 94.1% 74.9%
3969197 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.75 71.0 5.77e-01 100.0% 73.6%
3867774 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.75 70.0 4.70e-01 98.7% 44.7%
4561917 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 68.0 5.69e-01 96.1% 64.0%
398505 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.75 70.0 6.03e-01 100.0% 71.9%
3412938 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 69.0 5.90e-01 98.7% 76.5%
3409561 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 68.0 5.85e-01 96.7% 81.7%
3401378 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 69.0 5.67e-01 98.7% 78.0%
3407037 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 68.0 5.78e-01 96.7% 78.3%
3910699 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 69.0 5.49e-01 98.7% 78.2%
3412624 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 67.0 5.75e-01 96.7% 80.0%
4532481 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 69.0 5.48e-01 99.3% 72.8%
1063651 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 69.0 5.78e-01 98.7% 77.0%
1826904 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 69.0 5.76e-01 98.7% 68.5%
2512790 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.74 69.0 5.80e-01 98.7% 69.7%
3388883 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 67.0 5.72e-01 98.0% 78.3%
3405914 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 67.0 5.46e-01 98.0% 70.9%
3416167 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 69.0 5.73e-01 100.0% 73.6%
3415802 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 68.0 5.50e-01 100.0% 77.9%
22087 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.73 68.0 5.71e-01 98.7% 69.0%
3772106 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.73 68.0 5.87e-01 98.7% 68.0%
3545090 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.73 67.0 5.88e-01 98.0% 69.1%
3397229 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 66.0 5.67e-01 96.7% 73.0%
3755818 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 67.0 5.50e-01 100.0% 75.9%
3909175 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 67.0 5.38e-01 99.3% 77.9%
3538666 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 66.0 5.75e-01 98.7% 80.9%
3416144 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.70 64.0 5.76e-01 98.0% 74.8%
3224340 1.1.17.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › DUF316 0.70 64.0 5.37e-01 97.4% 77.6%
3420315 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.69 64.0 5.79e-01 99.3% 81.5%
3933050 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.67 61.0 4.91e-01 98.0% 75.5%
3383171 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 30.0 3.30e-01 79.1% 57.7%
3758107 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 30.0 3.70e-01 79.1% 76.0%
3707893 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 29.0 3.87e-01 78.4% 87.1%
3595126 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 31.0 3.91e-01 90.2% 84.2%
3591666 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.57 29.0 3.86e-01 77.1% 91.3%
4021578 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 29.0 3.27e-01 78.4% 62.5%
4019867 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 29.0 3.51e-01 79.1% 73.3%
3595233 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 30.0 3.73e-01 78.4% 83.2%
4487049 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.55 45.0 4.35e-01 96.7% 77.1%
3609622 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.55 30.0 3.62e-01 79.1% 80.0%
3250907 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 32.0 3.95e-01 96.7% 93.7%
3905647 304.9.1.151 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1, PF28441 0.53 34.0 3.01e-01 97.4% 44.2%
4014296 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.51 29.0 3.68e-01 79.1% 94.4%
D2 high residues 558-643
PDB
Domain cluster: rep: putative_3D_RNA-dependent_RNA_polymerase__YP_009553719__tremovirus_B1__2058161__D405-481
D3 medium residues 205-251_268-334_353-382
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009337735__Wenling_sobemo-like_virus_2__1923541__D4-91_185-200
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 23.9 2.20e-05 41.7% 7.6%
D4 medium residues 252-267_383-557
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_529897__Newbury_agent_1__331642__D58-79_192-241_281-399
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 95.7 3.80e-27 95.8% 42.7%
PF02123.22 RdRP_4 40.8 2.00e-10 67.5% 20.9%