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protein_A8
Euk-VirAotine_betaherpesvirus_1
protein_A8__YP_004940032__Aotine_betaherpesvirus_1__50290
Identity
- Accession:
- YP_004940032 ↗
- Protein ID:
- protein_A8
- Kingdom:
- euk
Quality
63.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Aotine_betaherpesvirus_1
TaxID: 50290
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 44-100
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.90 | 80.0 | 7.30e-01 | 100.0% | 75.7% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.85 | 76.0 | 6.64e-01 | 100.0% | 67.1% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.83 | 69.0 | 5.75e-01 | 100.0% | 53.6% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 71.0 | 5.17e-01 | 100.0% | 36.7% |
| 1gcbA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.82 | 69.0 | 4.10e-01 | 93.0% | 13.2% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.81 | 64.0 | 6.16e-01 | 86.0% | 80.0% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 70.0 | 6.16e-01 | 100.0% | 68.2% |
| 2vkzA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.79 | 70.0 | 4.51e-01 | 100.0% | 22.1% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.79 | 69.0 | 6.13e-01 | 100.0% | 68.3% |
| 3dmqA08 | 6.10.140.1500 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 63.0 | 5.62e-01 | 94.7% | 62.5% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 62.0 | 6.39e-01 | 87.7% | 100.0% |
| 4b3fX01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 63.0 | 3.86e-01 | 94.7% | 15.4% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.78 | 69.0 | 6.22e-01 | 100.0% | 73.1% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.78 | 70.0 | 7.05e-01 | 98.2% | 100.0% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.76 | 67.0 | 5.53e-01 | 100.0% | 95.1% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.75 | 65.0 | 6.21e-01 | 100.0% | 85.3% |
| 2mpnA00 | 6.10.140.1340 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 66.0 | 6.21e-01 | 98.2% | 89.7% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.75 | 60.0 | 4.85e-01 | 87.7% | 46.7% |
| 2e9fB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.75 | 56.0 | 4.69e-01 | 80.7% | 47.9% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 63.0 | 6.18e-01 | 94.7% | 93.5% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 63.0 | 5.30e-01 | 98.2% | 60.4% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 63.0 | 5.85e-01 | 96.5% | 79.2% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 64.0 | 5.99e-01 | 96.5% | 94.4% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.74 | 62.0 | 5.82e-01 | 96.5% | 81.9% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.73 | 63.0 | 5.75e-01 | 96.5% | 76.6% |
| 2l35A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.73 | 65.0 | 6.32e-01 | 100.0% | 95.2% |
| 3ilxA02 | 1.10.287.2170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 50.0 | 5.52e-01 | 78.9% | 93.2% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 60.0 | 5.97e-01 | 91.2% | 91.4% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 61.0 | 5.97e-01 | 96.5% | 92.2% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 62.0 | 5.91e-01 | 100.0% | 83.8% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 58.0 | 6.02e-01 | 89.5% | 100.0% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 60.0 | 4.96e-01 | 96.5% | 56.9% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 62.0 | 5.66e-01 | 98.2% | 89.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 64.0 | 4.69e-01 | 100.0% | 79.2% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 58.0 | 4.89e-01 | 96.5% | 55.1% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.71 | 61.0 | 4.66e-01 | 96.5% | 85.7% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.71 | 56.0 | 5.51e-01 | 87.7% | 82.3% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 61.0 | 5.74e-01 | 96.5% | 87.0% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.71 | 63.0 | 5.13e-01 | 100.0% | 85.8% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 61.0 | 4.82e-01 | 100.0% | 85.5% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 46.0 | 4.75e-01 | 70.2% | 70.4% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.70 | 54.0 | 3.62e-01 | 84.2% | 26.3% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 57.0 | 4.49e-01 | 96.5% | 43.6% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 53.0 | 5.49e-01 | 86.0% | 98.1% |
| 1p49A02 | 1.10.287.550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 60.0 | 6.02e-01 | 96.5% | 93.2% |
| 1ucuA01 | 6.10.280.190 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 52.0 | 4.91e-01 | 100.0% | 67.6% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.70 | 53.0 | 5.70e-01 | 87.7% | 100.0% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 57.0 | 4.25e-01 | 96.5% | 36.1% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 58.0 | 4.94e-01 | 98.2% | 57.6% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 58.0 | 5.22e-01 | 98.2% | 69.9% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.68 | 58.0 | 5.04e-01 | 98.2% | 65.9% |
| 2c2aA01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.67 | 58.0 | 5.03e-01 | 100.0% | 75.6% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.66 | 56.0 | 4.98e-01 | 100.0% | 64.3% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 56.0 | 5.02e-01 | 98.2% | 67.9% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.66 | 55.0 | 4.35e-01 | 100.0% | 44.3% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 56.0 | 5.18e-01 | 96.5% | 78.1% |
| 1kfdA02 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.64 | 54.0 | 5.10e-01 | 98.2% | 87.3% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 50.0 | 4.90e-01 | 89.5% | 81.5% |
| 2etnB01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.63 | 51.0 | 4.81e-01 | 98.2% | 75.0% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.63 | 49.0 | 3.00e-01 | 91.2% | 12.9% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 52.0 | 5.08e-01 | 98.2% | 89.1% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.59 | 51.0 | 4.78e-01 | 98.2% | 85.9% |
| 2yfqB01 | 1.10.8.1210 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 39.0 | 4.11e-01 | 84.2% | 82.7% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2674763 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.89 | 80.0 | 7.25e-01 | 100.0% | 74.7% |
| 4630202 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.86 | 77.0 | 6.62e-01 | 100.0% | 64.0% |
| 4107823 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.85 | 76.0 | 6.26e-01 | 100.0% | 57.0% |
| 2799599 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.85 | 76.0 | 6.59e-01 | 100.0% | 66.3% |
| 4109908 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.84 | 75.0 | 6.56e-01 | 100.0% | 67.1% |
| 4365052 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.84 | 75.0 | 6.27e-01 | 100.0% | 60.0% |
| 3570117 | 375.6.1.2 ↗ | few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 | 0.83 | 69.0 | 6.80e-01 | 91.2% | 91.7% |
| 3598977 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.82 | 70.0 | 6.15e-01 | 100.0% | 63.5% |
| 3976071 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.82 | 72.0 | 6.23e-01 | 100.0% | 71.1% |
| 5046799 | 10.13.1.10 ↗ | beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › Cation_ATPase_C | 0.79 | 70.0 | 4.01e-01 | 100.0% | 10.6% |
| 3256881 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.78 | 66.0 | 5.01e-01 | 100.0% | 39.3% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.77 | 67.0 | 5.87e-01 | 96.5% | 90.6% |
| 3212006 | 601.24.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0.76 | 65.0 | 5.01e-01 | 96.5% | 60.8% |
| 4965021 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.76 | 61.0 | 6.18e-01 | 100.0% | 90.9% |
| 3962893 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.76 | 67.0 | 5.68e-01 | 100.0% | 60.0% |
| 4206858 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.76 | 66.0 | 5.21e-01 | 96.5% | 51.3% |
| 3336677 | 605.1.1.132 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 | 0.76 | 64.0 | 5.85e-01 | 100.0% | 72.0% |
| 4619538 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.76 | 65.0 | 5.20e-01 | 96.5% | 51.3% |
| 5050356 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 62.0 | 5.76e-01 | 89.5% | 81.4% |
| 3504889 | 604.22.1.1 ↗ | alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N | 0.74 | 64.0 | 5.62e-01 | 98.2% | 68.2% |
| 3429502 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.73 | 63.0 | 3.91e-01 | 96.5% | 17.5% |
| 4110261 | 3748.1.1.2 ↗ | extended segments › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › CSN5_C | 0.73 | 61.0 | 5.47e-01 | 98.2% | 67.1% |
| 3180119 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.72 | 59.0 | 5.18e-01 | 89.5% | 62.4% |
| 3397165 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.71 | 59.0 | 5.83e-01 | 89.5% | 93.3% |
| 3451935 | 192.8.1.359 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF641 | 0.71 | 58.0 | 5.89e-01 | 96.5% | 94.5% |
| 4940986 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.70 | 60.0 | 5.16e-01 | 100.0% | 65.3% |
| 4860885 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.70 | 61.0 | 5.04e-01 | 100.0% | 74.3% |
| 3848917 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.70 | 58.0 | 5.18e-01 | 96.5% | 90.6% |
| 3465231 | 192.15.1.189 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Frigida | 0.68 | 53.0 | 4.94e-01 | 96.5% | 67.5% |
| 3764851 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.67 | 57.0 | 5.01e-01 | 100.0% | 94.4% |
| 4038778 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.65 | 55.0 | 4.50e-01 | 100.0% | 53.0% |