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protein_Allo37
Euk-VirCyprinid_herpesvirus_1
protein_Allo37__YP_007003753__Cyprinid_herpesvirus_1__317858
Identity
- Accession:
- YP_007003753 ↗
- Protein ID:
- protein_Allo37
- Kingdom:
- euk
Quality
50.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Alloherpesviridae›
Cyvirus›
Cyprinid_herpesvirus_1
TaxID: 317858
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 24-108
Domain cluster:
rep: protein_Allo37__YP_007003909__Cyprinid_herpesvirus_2__317878__D42-104
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.84 | 58.0 | 4.98e-01 | 70.6% | 51.2% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.78 | 54.0 | 5.63e-01 | 71.8% | 80.8% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.76 | 58.0 | 4.13e-01 | 80.0% | 73.1% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.75 | 55.0 | 5.05e-01 | 77.6% | 66.7% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 49.0 | 5.03e-01 | 74.1% | 81.0% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.69 | 49.0 | 5.08e-01 | 74.1% | 83.1% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.67 | 47.0 | 4.50e-01 | 74.1% | 73.3% |
| 4j0eA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.65 | 45.0 | 3.45e-01 | 72.9% | 51.5% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 55.0 | 4.54e-01 | 92.9% | 68.7% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 43.0 | 4.13e-01 | 70.6% | 58.8% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.63 | 45.0 | 4.23e-01 | 75.3% | 67.9% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 48.0 | 4.13e-01 | 85.9% | 97.1% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.61 | 43.0 | 4.53e-01 | 75.3% | 85.1% |
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 42.0 | 4.17e-01 | 75.3% | 74.7% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.58 | 43.0 | 4.27e-01 | 78.8% | 93.1% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 40.0 | 4.17e-01 | 74.1% | 81.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4027464 | 7558.1.1.0 ↗ | a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase | 0.79 | 54.0 | 3.54e-01 | 70.6% | 18.2% |
| 1144608 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.78 | 58.0 | 5.24e-01 | 77.6% | 59.6% |
| 3479094 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.78 | 55.0 | 3.85e-01 | 72.9% | 25.3% |
| 3539986 | 5058.1.1.90 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TMEM169 | 0.77 | 61.0 | 6.43e-01 | 84.7% | 100.0% |
| 3770340 | 5041.1.1.2 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM169 | 0.76 | 61.0 | 5.71e-01 | 85.9% | 75.2% |
| 3281127 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.76 | 55.0 | 5.40e-01 | 75.3% | 73.3% |
| 3485149 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.76 | 55.0 | 3.92e-01 | 76.5% | 27.3% |
| 4951933 | 3567.1.1.190 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › HisKA | 0.75 | 52.0 | 5.47e-01 | 72.9% | 81.3% |
| 2625677 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.75 | 55.0 | 5.05e-01 | 77.6% | 66.7% |
| 3391978 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.74 | 54.0 | 5.76e-01 | 77.6% | 96.0% |
| 4101335 | 2006.1.4.8 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5 | 0.73 | 53.0 | 3.86e-01 | 76.5% | 42.2% |
| 3573038 | 4207.1.1.99 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › PF28139 | 0.72 | 51.0 | 5.03e-01 | 72.9% | 77.8% |
| 3862031 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.72 | 53.0 | 3.71e-01 | 76.5% | 25.9% |
| 3851320 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.72 | 53.0 | 3.65e-01 | 77.6% | 26.3% |
| 3785816 | 4.1.1.369 ↗ | beta barrels › SH3 › SH3 › SH3 › Not3 | 0.71 | 51.0 | 4.34e-01 | 76.5% | 68.6% |
| 3461932 | 3922.1.1.189 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF630 | 0.69 | 48.0 | 4.70e-01 | 72.9% | 70.5% |
| 3739286 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 48.0 | 3.52e-01 | 72.9% | 27.8% |
| 4449117 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.68 | 48.0 | 4.95e-01 | 74.1% | 83.7% |
| 3186617 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.68 | 52.0 | 3.51e-01 | 82.4% | 40.2% |
| 3244309 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.67 | 50.0 | 3.57e-01 | 80.0% | 64.5% |
| 3613914 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.66 | 45.0 | 4.76e-01 | 71.8% | 81.3% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.65 | 51.0 | 4.05e-01 | 83.5% | 84.1% |
| 3236471 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.64 | 55.0 | 3.94e-01 | 100.0% | 93.9% |
| 2409294 | 601.52.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › Flagellin_N | 0.63 | 46.0 | 3.96e-01 | 76.5% | 54.8% |
| 3963152 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.63 | 45.0 | 3.07e-01 | 77.6% | 20.9% |
| 3462297 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.63 | 43.0 | 4.57e-01 | 74.1% | 82.7% |
| 4649366 | 304.58.1.0 ↗ | a+b two layers › Alpha-beta plaits › FepE-like › FepE-like | 0.61 | 43.0 | 3.05e-01 | 74.1% | 24.2% |
| 4588350 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 54.0 | 4.51e-01 | 100.0% | 93.3% |
| 4665988 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.60 | 42.0 | 3.97e-01 | 74.1% | 60.0% |
| 4385544 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 43.0 | 4.49e-01 | 75.3% | 89.3% |
| 3736652 | 192.29.1.102 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Fung_rhodopsin | 0.59 | 45.0 | 4.58e-01 | 81.2% | 93.8% |
| 3940619 | 109.4.1.2546 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3, TPR_8, TPR_17, CHIP_TPR_N | 0.55 | 39.0 | 3.12e-01 | 77.6% | 34.5% |
D2
medium
residues 109-198_357-379
D3
medium
residues 199-221_312-356
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v3aA03 | 3.30.390.120 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.59 | 34.0 | 3.55e-01 | 89.7% | 60.9% |
| 1twfI01 | 2.20.25.10 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.56 | 36.0 | 4.14e-01 | 100.0% | 97.8% |
| 1txdA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.56 | 43.0 | 3.67e-01 | 88.2% | 89.3% |
| 1nr4C00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.55 | 39.0 | 3.96e-01 | 94.1% | 75.8% |
| 1goiA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.55 | 42.0 | 3.88e-01 | 85.3% | 100.0% |
| 3arxA03 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.55 | 40.0 | 3.73e-01 | 77.9% | 98.8% |
| 2jx8A00 | 2.20.70.10 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › | 0.55 | 29.0 | 3.40e-01 | 83.8% | 74.5% |
| 3alfA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.55 | 41.0 | 4.09e-01 | 80.9% | 98.6% |
| 5dezA03 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.54 | 42.0 | 4.16e-01 | 85.3% | 100.0% |
| 2iz4A02 | 2.20.25.590 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.54 | 32.0 | 3.67e-01 | 88.2% | 92.9% |
| 3k6oA01 | 2.40.50.500 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › NigD-like N-terminal OB domain | 0.54 | 33.0 | 3.25e-01 | 79.4% | 54.8% |
| 1owqA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.53 | 39.0 | 3.97e-01 | 79.4% | 98.5% |
| 2x8nA01 | 3.30.2020.40 | Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › Uncharacterised protein PF10387, DUF2442 | 0.52 | 39.0 | 3.58e-01 | 83.8% | 71.1% |
| 1itxA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.52 | 38.0 | 3.79e-01 | 79.4% | 98.6% |
| 5xpyA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.52 | 45.0 | 3.90e-01 | 100.0% | 74.1% |
| 6y48D01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 41.0 | 2.80e-01 | 94.1% | 84.2% |
| 6rwcA02 | 2.20.25.590 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.51 | 29.0 | 3.34e-01 | 82.4% | 89.7% |
| 4gp3A03 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.51 | 40.0 | 3.37e-01 | 88.2% | 94.3% |
| 1ckmA01 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.51 | 42.0 | 3.29e-01 | 94.1% | 95.5% |
| 2eyzA03 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.50 | 32.0 | 2.95e-01 | 80.9% | 47.3% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 990993 | 4.8.1.0 ↗ | beta barrels › SH3 › Chromo domain-like › Chromo domain-like | 0.60 | 39.0 | 4.33e-01 | 98.5% | 93.9% |
| 996859 | 375.8.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Zinc-binding domain of translation initiation factor 2 beta › Zinc-binding domain of translation initiation factor 2 beta | 0.58 | 40.0 | 4.24e-01 | 94.1% | 83.3% |
| 2455590 | 284.2.1.1 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain › Glyco_hydro_18 | 0.58 | 46.0 | 3.66e-01 | 89.7% | 62.3% |
| 3661622 | 64.1.1.1 ↗ | beta meanders › WW domain-like › WW domain › WW domain › WW | 0.58 | 31.0 | 3.74e-01 | 83.8% | 85.0% |
| 4025894 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.57 | 40.0 | 3.48e-01 | 73.5% | 77.1% |
| 4937515 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.56 | 39.0 | 3.61e-01 | 73.5% | 95.6% |
| 4218238 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.56 | 40.0 | 4.11e-01 | 76.5% | 100.0% |
| 3581945 | 220.1.1.132 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › KRIT1_FRMD8_FERM_C | 0.56 | 42.0 | 4.40e-01 | 95.6% | 91.7% |
| 3265458 | 2004.1.1.81 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GBP | 0.55 | 42.0 | 2.77e-01 | 83.8% | 57.6% |
| 4943339 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.55 | 37.0 | 3.35e-01 | 91.2% | 48.0% |
| 2649747 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.55 | 40.0 | 3.95e-01 | 77.9% | 98.6% |
| 3416287 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.55 | 48.0 | 3.85e-01 | 100.0% | 80.4% |
| 3263018 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 45.0 | 3.99e-01 | 100.0% | 63.0% |
| 4948490 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 42.0 | 4.15e-01 | 100.0% | 78.7% |
| 3505640 | 375.1.1.19 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › RNA_POL_M_15KD | 0.54 | 35.0 | 3.70e-01 | 100.0% | 76.7% |
| 3419793 | 5.1.10.3 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 12-bladed › DUF295 | 0.54 | 40.0 | 3.22e-01 | 89.7% | 40.7% |
| 3702861 | 375.1.1.19 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › RNA_POL_M_15KD | 0.53 | 35.0 | 3.79e-01 | 100.0% | 81.8% |
| 4028185 | 375.1.1.19 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › RNA_POL_M_15KD | 0.53 | 36.0 | 3.94e-01 | 100.0% | 94.0% |
| 3601811 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.53 | 41.0 | 3.08e-01 | 86.8% | 43.9% |
| 3612587 | 4357.1.1.0 ↗ | beta barrels › WWE domain › WWE domain › WWE domain | 0.52 | 41.0 | 4.33e-01 | 83.8% | 100.0% |
| 3189994 | 375.1.1.19 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › RNA_POL_M_15KD | 0.52 | 33.0 | 3.06e-01 | 100.0% | 46.7% |
| 4883688 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.52 | 39.0 | 3.85e-01 | 82.4% | 100.0% |
| 3403184 | 719.2.1.1 ↗ | beta barrels › XRCC4, N-terminal domain-like › NE0471 N-terminal domain-like › NE0471 N-terminal domain-like › GBBH-like_N | 0.52 | 41.0 | 3.70e-01 | 88.2% | 67.0% |
| 3499652 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.52 | 45.0 | 3.01e-01 | 98.5% | 38.6% |
| 4618205 | 604.1.1.150 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 | 0.52 | 33.0 | 2.80e-01 | 72.1% | 35.8% |
| 3247824 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.51 | 45.0 | 3.96e-01 | 100.0% | 82.9% |
| 3268247 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 39.0 | 2.56e-01 | 85.3% | 32.5% |
| 3476114 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.50 | 38.0 | 2.43e-01 | 85.3% | 28.1% |
D4
medium
residues 222-311
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 39.0 | 3.70e-01 | 100.0% | 44.0% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 58.0 | 5.27e-01 | 92.2% | 96.7% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.69 | 55.0 | 5.61e-01 | 87.8% | 95.5% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.68 | 41.0 | 4.38e-01 | 100.0% | 70.1% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.68 | 37.0 | 4.81e-01 | 100.0% | 98.0% |
| 1a5tA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.68 | 53.0 | 4.93e-01 | 85.6% | 81.9% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.68 | 39.0 | 3.85e-01 | 100.0% | 52.6% |
| 2hxiB02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 51.0 | 4.53e-01 | 82.2% | 97.0% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.67 | 56.0 | 5.52e-01 | 94.4% | 91.9% |
| 1lj2A00 | 1.20.5.970 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Nonstructural RNA-binding protein | 0.66 | 45.0 | 4.29e-01 | 75.6% | 59.4% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 37.0 | 3.46e-01 | 98.9% | 45.0% |
| 1iqpA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.66 | 52.0 | 5.20e-01 | 87.8% | 88.3% |
| 3u61D03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.65 | 53.0 | 5.31e-01 | 91.1% | 87.9% |
| 3of4A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.65 | 44.0 | 3.39e-01 | 70.0% | 49.8% |
| 2g7gA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 49.0 | 3.88e-01 | 84.4% | 66.5% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 45.0 | 3.61e-01 | 75.6% | 57.4% |
| 4adzA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.63 | 38.0 | 3.80e-01 | 100.0% | 58.9% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.62 | 36.0 | 3.69e-01 | 100.0% | 58.1% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.61 | 39.0 | 3.37e-01 | 98.9% | 42.9% |
| 2rn7A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 33.0 | 3.74e-01 | 80.0% | 69.7% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.61 | 48.0 | 4.54e-01 | 88.9% | 84.1% |
| 3bqoA00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.61 | 52.0 | 4.11e-01 | 98.9% | 83.7% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 36.0 | 3.51e-01 | 100.0% | 52.5% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 42.0 | 4.27e-01 | 72.2% | 100.0% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 44.0 | 4.29e-01 | 77.8% | 70.7% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 42.0 | 4.33e-01 | 74.4% | 88.1% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.59 | 40.0 | 3.91e-01 | 70.0% | 97.1% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.58 | 41.0 | 3.42e-01 | 73.3% | 84.5% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 39.0 | 4.14e-01 | 100.0% | 78.5% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.58 | 46.0 | 4.12e-01 | 88.9% | 88.5% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.57 | 47.0 | 4.58e-01 | 92.2% | 85.0% |
| 2hxoA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 47.0 | 4.14e-01 | 94.4% | 97.2% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 42.0 | 4.00e-01 | 81.1% | 66.4% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 46.0 | 4.24e-01 | 93.3% | 100.0% |
| 3rrkA02 | 1.20.1460.20 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › | 0.54 | 37.0 | 3.14e-01 | 85.6% | 41.3% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 37.0 | 3.41e-01 | 100.0% | 54.7% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 3.47e-01 | 87.8% | 58.5% |
| 3n98A01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.53 | 41.0 | 2.70e-01 | 84.4% | 69.5% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.53 | 34.0 | 3.53e-01 | 100.0% | 70.7% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 37.0 | 3.84e-01 | 76.7% | 89.7% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 40.0 | 3.38e-01 | 100.0% | 50.3% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3608012 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.74 | 41.0 | 4.29e-01 | 100.0% | 58.8% |
| 3607086 | 4992.1.1.0 ↗ | extended segments › RelB-like › RelB-like › RelB-like | 0.74 | 41.0 | 4.38e-01 | 100.0% | 62.5% |
| 3385717 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.70 | 39.0 | 3.15e-01 | 100.0% | 29.4% |
| 5073062 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.68 | 57.0 | 5.33e-01 | 93.3% | 74.8% |
| 4074434 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.68 | 50.0 | 5.22e-01 | 76.7% | 88.7% |
| 5075237 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.68 | 57.0 | 5.85e-01 | 92.2% | 100.0% |
| 3476610 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 39.0 | 3.48e-01 | 100.0% | 40.0% |
| 3695361 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 39.0 | 3.52e-01 | 100.0% | 41.6% |
| 3902528 | 192.2.1.57 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › TBCA_PH | 0.67 | 39.0 | 3.72e-01 | 100.0% | 49.5% |
| 4975293 | 601.28.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 | 0.67 | 54.0 | 5.28e-01 | 88.9% | 92.0% |
| 5036349 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.66 | 54.0 | 5.34e-01 | 88.9% | 86.3% |
| 3559586 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 37.0 | 3.16e-01 | 100.0% | 33.3% |
| 3171901 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.66 | 57.0 | 5.63e-01 | 96.7% | 96.8% |
| 4948161 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.66 | 52.0 | 5.19e-01 | 87.8% | 83.2% |
| 4169641 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.65 | 51.0 | 5.13e-01 | 84.4% | 88.9% |
| 5046177 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.65 | 51.0 | 5.18e-01 | 84.4% | 90.0% |
| 3923332 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.65 | 53.0 | 5.22e-01 | 88.9% | 88.4% |
| 5020255 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.65 | 49.0 | 5.04e-01 | 81.1% | 91.8% |
| 2388822 | 191.1.1.1 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_1 | 0.65 | 49.0 | 4.48e-01 | 81.1% | 95.8% |
| 5045230 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.65 | 46.0 | 4.76e-01 | 75.6% | 89.4% |
| 4285641 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.64 | 51.0 | 5.10e-01 | 87.8% | 87.4% |
| 4990683 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.64 | 54.0 | 5.21e-01 | 93.3% | 86.4% |
| 3602354 | 1030.1.1.1 ↗ | alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A | 0.64 | 51.0 | 4.70e-01 | 87.8% | 72.5% |
| 3473725 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.64 | 51.0 | 5.12e-01 | 87.8% | 88.9% |
| 3449672 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.63 | 49.0 | 4.87e-01 | 84.4% | 85.3% |
| 5049036 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.63 | 51.0 | 5.12e-01 | 87.8% | 90.0% |
| 5049970 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.63 | 55.0 | 4.46e-01 | 100.0% | 86.7% |
| 4479932 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.63 | 53.0 | 5.32e-01 | 98.9% | 93.3% |
| 4949146 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.63 | 44.0 | 4.58e-01 | 74.4% | 98.8% |
| 3172162 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.62 | 45.0 | 4.27e-01 | 76.7% | 69.1% |
| 3828958 | 602.1.1.0 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like | 0.61 | 49.0 | 3.59e-01 | 90.0% | 94.7% |
| 3938941 | 109.4.1.649 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4807 | 0.59 | 41.0 | 3.63e-01 | 71.1% | 85.4% |
| 3348808 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.59 | 42.0 | 2.78e-01 | 76.7% | 18.3% |
| 3707035 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.58 | 47.0 | 3.73e-01 | 92.2% | 57.6% |
| 3518039 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.58 | 38.0 | 3.60e-01 | 100.0% | 57.1% |
| 3201166 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.56 | 41.0 | 3.58e-01 | 76.7% | 88.1% |
| 5064089 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.55 | 40.0 | 4.25e-01 | 77.8% | 93.3% |
| 3889164 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.54 | 38.0 | 3.89e-01 | 75.6% | 100.0% |
| 4162677 | 1198.1.1.0 ↗ | alpha bundles › BTA121 › BTA121 › BTA121 | 0.53 | 40.0 | 3.81e-01 | 82.2% | 76.4% |
D5
medium
residues 467-533
D6
medium
residues 610-679