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protein_G49
Euk-VirHuman_gammaherpesvirus_4
protein_G49__YP_401675__Human_gammaherpesvirus_4__10376
Identity
- Accession:
- YP_401675 ↗
- Protein ID:
- protein_G49
- Kingdom:
- euk
Quality
82.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Lymphocryptovirus›
human_gammaherpesvirus_4
TaxID: 10376
Cluster
View cluster (19 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 15-74
Domain cluster:
rep: ORF41__NP_733894__Callitrichine_gammaherpesvirus_3__106331__D1-70
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 65.3 | 6.70e-18 | 88.3% | 18.9% |
D2
medium
residues 75-225
Domain cluster:
rep: BRRF1__YP_010087490__Phascolarctid_gammaherpesvirus_1__2249313__D80-237
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 170.3 | 6.70e-50 | 100.0% | 53.1% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qsbA00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.78 | 43.0 | 5.68e-01 | 94.7% | 97.6% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.67 | 46.0 | 4.68e-01 | 100.0% | 71.1% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.65 | 42.0 | 4.27e-01 | 100.0% | 65.8% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.64 | 36.0 | 3.85e-01 | 84.1% | 63.3% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 40.0 | 4.05e-01 | 100.0% | 63.0% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 40.0 | 4.11e-01 | 100.0% | 68.5% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 40.0 | 3.96e-01 | 100.0% | 64.2% |
| 4ebjA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.59 | 34.0 | 3.61e-01 | 82.8% | 63.8% |
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.58 | 38.0 | 3.68e-01 | 72.8% | 58.1% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.57 | 28.0 | 3.18e-01 | 98.7% | 61.4% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 40.0 | 3.82e-01 | 100.0% | 64.3% |
| 1or4B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 39.0 | 3.84e-01 | 70.9% | 92.4% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 43.0 | 3.55e-01 | 83.4% | 95.2% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 31.0 | 3.50e-01 | 85.4% | 70.8% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 39.0 | 4.01e-01 | 86.1% | 78.5% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 41.0 | 3.48e-01 | 82.8% | 93.7% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 37.0 | 3.68e-01 | 100.0% | 67.9% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.52 | 40.0 | 4.00e-01 | 96.0% | 79.1% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 37.0 | 3.56e-01 | 74.2% | 66.3% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 30.0 | 3.27e-01 | 84.8% | 69.1% |
| 2iw3B01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 37.0 | 2.89e-01 | 73.5% | 49.5% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.51 | 36.0 | 3.38e-01 | 100.0% | 59.8% |
| 6mcjA00 | 1.10.2090.10 | Mainly Alpha › Orthogonal Bundle › orange carotenoid protein, domain 2 › Orange carotenoid-binding protein, N-terminal domain | 0.51 | 36.0 | 3.68e-01 | 84.8% | 75.2% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.50 | 46.0 | 4.14e-01 | 100.0% | 72.9% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2426517 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.89 | 83.0 | 6.62e-01 | 100.0% | 54.3% |
| 1923803 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.87 | 82.0 | 6.43e-01 | 100.0% | 52.1% |
| 4133341 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.63 | 36.0 | 4.07e-01 | 84.8% | 71.7% |
| 4935971 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.60 | 44.0 | 4.40e-01 | 100.0% | 73.5% |
| 5082862 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.59 | 43.0 | 4.22e-01 | 100.0% | 69.1% |
| 4950656 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.58 | 37.0 | 3.99e-01 | 87.4% | 73.8% |
| 3394844 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.57 | 44.0 | 3.66e-01 | 82.8% | 90.0% |
| 3406815 | 5001.1.1.50 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF4791 | 0.56 | 44.0 | 4.12e-01 | 84.1% | 99.0% |
| 3509455 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 40.0 | 3.90e-01 | 87.4% | 69.3% |
| 5041194 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.54 | 38.0 | 3.79e-01 | 87.4% | 69.7% |
| 3518846 | 3861.1.1.1 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR | 0.54 | 38.0 | 3.75e-01 | 72.8% | 73.3% |
| 4166070 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.53 | 49.0 | 4.01e-01 | 100.0% | 81.1% |
| 3242228 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.53 | 33.0 | 3.65e-01 | 82.8% | 77.5% |
| 3996345 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.52 | 44.0 | 4.40e-01 | 100.0% | 84.3% |
| 2420863 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.52 | 37.0 | 3.46e-01 | 74.2% | 84.3% |
| 3623413 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.51 | 46.0 | 4.04e-01 | 98.0% | 93.2% |
| 3239359 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 41.0 | 3.31e-01 | 86.8% | 90.0% |
| 3392874 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.50 | 39.0 | 3.28e-01 | 84.1% | 89.7% |