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protein_ORF121

Euk-Vir

Cyprinid_herpesvirus_2

protein_ORF121__YP_007003937__Cyprinid_herpesvirus_2__317878

Identity

Accession:
YP_007003937 ↗
Protein ID:
protein_ORF121
Kingdom:
euk

Quality

51.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 74-166
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 69.0 6.10e-01 100.0% 84.3%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 43.0 4.23e-01 100.0% 52.0%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.76 55.0 4.23e-01 75.3% 86.5%
6humG01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.75 54.0 4.51e-01 76.3% 45.6%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 66.0 5.94e-01 100.0% 90.8%
3nyjA00 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.74 54.0 4.32e-01 77.4% 52.5%
5xtck00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 52.0 5.19e-01 74.2% 76.3%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.72 65.0 6.42e-01 100.0% 99.0%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 62.0 5.63e-01 98.9% 95.4%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.70 62.0 5.80e-01 98.9% 99.1%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.70 48.0 4.08e-01 71.0% 79.9%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.70 62.0 5.58e-01 100.0% 71.8%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 53.0 3.79e-01 81.7% 82.5%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 48.0 4.19e-01 73.1% 66.7%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 45.0 4.43e-01 73.1% 63.4%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 45.0 4.62e-01 74.2% 71.1%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.67 59.0 5.32e-01 100.0% 92.4%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.66 59.0 4.72e-01 100.0% 70.6%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.66 58.0 5.21e-01 98.9% 94.7%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 59.0 5.24e-01 100.0% 95.6%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.65 58.0 5.41e-01 100.0% 88.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 44.0 4.11e-01 71.0% 88.0%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 50.0 3.64e-01 84.9% 80.5%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 44.0 3.47e-01 73.1% 83.6%
2xgsB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 36.0 4.03e-01 73.1% 72.6%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 48.0 3.52e-01 84.9% 77.1%
4c0eA01 1.25.40.790 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 48.0 3.36e-01 94.6% 26.9%
1zbpA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 37.0 3.87e-01 73.1% 63.5%
2yk0A03 1.20.58.1930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 45.0 3.38e-01 77.4% 61.7%
3zgxA02 6.10.140.1720 Special › Helix non-globular › Helix Hairpins › 0.60 41.0 4.23e-01 100.0% 72.5%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 41.0 3.90e-01 100.0% 61.9%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 46.0 4.21e-01 82.8% 88.3%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 51.0 4.42e-01 100.0% 96.7%
1cmjA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.58 46.0 3.03e-01 84.9% 49.1%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 42.0 4.53e-01 100.0% 92.3%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.56 39.0 4.61e-01 94.6% 100.0%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 42.0 4.00e-01 80.6% 77.7%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.56 42.0 4.08e-01 80.6% 84.0%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 45.0 3.44e-01 87.1% 50.5%
4fm3A00 1.20.1270.390 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 38.0 3.80e-01 72.0% 74.7%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.54 40.0 4.52e-01 100.0% 97.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 41.0 4.13e-01 79.6% 97.8%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 44.0 3.78e-01 100.0% 56.8%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 41.0 3.92e-01 80.6% 89.6%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.54 39.0 4.00e-01 77.4% 78.4%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.53 46.0 4.18e-01 96.8% 80.2%
2hyjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.84e-01 95.7% 80.3%
1oshA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 43.0 3.44e-01 98.9% 82.4%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 44.0 3.41e-01 98.9% 81.1%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 45.0 4.34e-01 96.8% 87.9%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5078792 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.77 70.0 6.61e-01 100.0% 91.8%
3358814 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.77 70.0 5.07e-01 100.0% 60.8%
3621550 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 48.0 4.35e-01 75.3% 48.3%
2755018 3843.1.1.1 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 0.77 55.0 5.40e-01 74.2% 79.6%
5000174 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.76 69.0 6.77e-01 100.0% 93.0%
3611706 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.75 66.0 5.95e-01 100.0% 70.0%
3395959 5086.1.1.166 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PEX11 0.73 53.0 5.28e-01 75.3% 98.9%
4392222 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.73 65.0 5.09e-01 100.0% 68.5%
3819233 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.73 43.0 4.03e-01 100.0% 47.8%
3272618 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 64.0 5.44e-01 100.0% 81.9%
3499430 109.4.1.2047 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_8, TPR_16, TPR_19 0.72 50.0 3.07e-01 72.0% 14.1%
2703780 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.71 63.0 5.16e-01 98.9% 97.7%
4929363 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.71 50.0 4.69e-01 73.1% 93.9%
3832084 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 50.0 5.51e-01 73.1% 100.0%
3213281 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.71 53.0 3.78e-01 78.5% 86.3%
5079648 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.71 63.0 6.39e-01 98.9% 100.0%
3098420 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 40.0 3.86e-01 100.0% 47.7%
5024421 133.2.1.1 alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C 0.70 50.0 3.89e-01 74.2% 53.0%
4488200 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 50.0 4.73e-01 74.2% 89.9%
3908810 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.70 53.0 3.72e-01 80.6% 79.7%
4561477 5001.1.1.39 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.69 53.0 3.72e-01 82.8% 41.4%
3276774 109.4.1.1207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TmcB 0.67 49.0 2.99e-01 77.4% 15.5%
4003695 109.4.1.2564 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_10, TPR_19 0.67 49.0 2.92e-01 76.3% 13.0%
4586182 5001.1.1.39 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.67 59.0 4.24e-01 100.0% 80.4%
3553985 109.4.1.148 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 0.65 50.0 3.15e-01 82.8% 67.7%
3591771 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.65 47.0 4.03e-01 75.3% 69.3%
4513880 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.65 56.0 3.76e-01 100.0% 65.6%
5018512 3558.1.1.4 alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain › T1RH-like_C 0.65 46.0 4.49e-01 73.1% 97.0%
3839870 109.4.1.206 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.64 47.0 3.54e-01 75.3% 45.0%
3980912 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 56.0 5.23e-01 100.0% 88.7%
5049932 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 52.0 4.52e-01 90.3% 92.9%
3213527 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.62 44.0 3.20e-01 75.3% 79.3%
3834362 3832.1.1.2 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › PF25968 0.61 52.0 3.24e-01 95.7% 18.2%
4027317 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 44.0 2.92e-01 76.3% 32.4%
3783914 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.60 47.0 2.95e-01 82.8% 48.5%
4012748 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.60 46.0 3.14e-01 80.6% 47.1%
3960319 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.60 46.0 3.72e-01 80.6% 62.9%
3707729 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 46.0 3.79e-01 82.8% 81.6%
4015516 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 43.0 2.76e-01 76.3% 24.1%
3732353 109.4.1.128 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 0.59 42.0 3.04e-01 74.2% 34.5%
1759954 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.59 49.0 3.30e-01 95.7% 38.1%
3933694 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 42.0 3.33e-01 74.2% 58.9%
3657382 109.4.1.1567 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Frigida 0.57 39.0 3.26e-01 74.2% 40.0%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.57 42.0 3.97e-01 78.5% 95.7%
3943720 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 43.0 3.83e-01 82.8% 72.1%
5061420 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.56 43.0 3.16e-01 80.6% 41.6%
3935426 109.4.1.791 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.56 44.0 4.42e-01 84.9% 89.5%
3172208 109.4.1.1298 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fes1, PF28415 0.55 40.0 2.81e-01 74.2% 41.0%
4027749 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 44.0 2.78e-01 83.9% 25.6%
3317246 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.54 49.0 4.58e-01 94.6% 81.8%
3735874 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.54 45.0 2.86e-01 89.2% 90.3%
3605667 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 3.68e-01 100.0% 71.9%
3787103 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.51 45.0 3.92e-01 96.8% 71.4%