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protein_ORF22

Euk-Vir

Cyprinid_herpesvirus_1

protein_ORF22__YP_007003694__Cyprinid_herpesvirus_1__317858

Identity

Accession:
YP_007003694 ↗
Protein ID:
protein_ORF22
Kingdom:
euk

Quality

72.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 127-272
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ibwA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 35.0 4.61e-01 83.6% 98.7%
3tupA02 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.58 38.0 4.48e-01 87.7% 100.0%
3g87A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.57 27.0 3.80e-01 84.2% 95.5%
4bzaA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.56 28.0 3.87e-01 84.2% 100.0%
3hxiA01 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.56 44.0 4.21e-01 96.6% 71.3%
2jgbA01 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.55 43.0 4.08e-01 95.9% 69.4%
4b6uA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.54 43.0 3.87e-01 96.6% 59.9%
2wmcA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.54 44.0 4.19e-01 99.3% 73.6%
5abxA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.53 43.0 4.15e-01 99.3% 74.6%
2ldkA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 38.0 3.62e-01 74.7% 94.2%
3rqwA01 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.53 42.0 3.89e-01 84.9% 72.6%
3igqC00 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.52 42.0 3.92e-01 84.9% 69.0%
1ap8A00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.52 43.0 3.85e-01 98.6% 62.0%
2x8xX02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.52 27.0 3.66e-01 85.6% 97.4%
6wimA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.51 27.0 3.57e-01 84.9% 98.6%
1pzdA02 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.51 36.0 4.00e-01 92.5% 93.0%
2lf2A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 35.0 3.32e-01 70.5% 82.3%
1vm6A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.50 26.0 3.18e-01 87.7% 80.7%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4104956 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 36.0 4.72e-01 84.2% 98.8%
136544 304.8.1.8 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_4 0.64 36.0 4.68e-01 83.6% 100.0%
3786112 317.1.1.0 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase 0.59 50.0 4.82e-01 100.0% 80.6%
3605908 304.31.1.3 a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › FAZ1_cons 0.58 46.0 5.00e-01 84.9% 100.0%
3795151 304.8.1.71 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF7636 0.58 36.0 4.21e-01 87.7% 89.0%
3411428 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.57 46.0 4.75e-01 87.0% 99.3%
3519512 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.56 45.0 4.26e-01 95.2% 71.8%
3190647 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.56 43.0 3.90e-01 95.9% 59.0%
4015708 317.1.1.0 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase 0.56 43.0 3.92e-01 95.9% 60.5%
3894796 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.55 43.0 3.98e-01 95.9% 64.9%
222897 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.55 44.0 3.96e-01 96.6% 60.9%
3282852 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.54 39.0 3.86e-01 74.0% 80.0%
3595913 317.1.1.0 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase 0.54 42.0 3.90e-01 95.9% 63.8%
4020284 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.54 48.0 4.26e-01 100.0% 72.5%
3699127 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.54 42.0 3.92e-01 95.9% 64.9%
3234427 206.1.1.78 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kinase-like 0.53 43.0 3.36e-01 87.7% 71.6%
3609602 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.53 42.0 3.85e-01 97.3% 62.6%
4017396 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.53 43.0 3.77e-01 95.9% 57.3%
3511081 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.53 41.0 4.03e-01 95.9% 73.3%
148460 11.12.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.53 43.0 3.90e-01 85.6% 81.8%
3651121 331.3.1.31 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF1990 0.53 38.0 3.43e-01 75.3% 93.3%
3478629 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.53 45.0 4.07e-01 99.3% 67.5%
3218655 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 43.0 3.29e-01 88.4% 70.3%
3695267 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.50 44.0 3.78e-01 95.9% 60.0%
D2 medium residues 1-65_276-314
PDB
D3 medium residues 66-126
PDB
D4 medium residues 315-425
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tacB01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.71 55.0 5.28e-01 91.9% 70.9%
3bs7A00 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.69 46.0 5.44e-01 78.4% 100.0%
1kxpD02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.58 31.0 3.42e-01 82.9% 63.6%
7ri3A02 1.10.490.40 Mainly Alpha › Orthogonal Bundle › Globin-like › Diphtheria toxin, translocation domain 0.55 46.0 4.09e-01 93.7% 83.3%
1wwmA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.53 41.0 3.53e-01 83.8% 83.9%
2gz4A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.52 41.0 3.44e-01 85.6% 58.0%
1dvgA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 41.0 3.34e-01 84.7% 78.0%
7yugA01 1.10.10.2590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BEN domain 0.51 39.0 3.90e-01 79.3% 79.6%
3cs1A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.51 35.0 3.53e-01 89.2% 70.6%
5jolA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.50 32.0 3.66e-01 82.9% 87.8%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3872476 102.1.1.1 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_1 0.74 55.0 4.42e-01 87.4% 42.0%
3559298 102.1.1.1 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_1 0.73 57.0 5.76e-01 91.0% 82.7%
183130 102.1.1.1 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_1 0.71 55.0 5.28e-01 91.9% 70.9%
3498986 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.71 56.0 5.69e-01 90.1% 85.2%
4214027 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.61 36.0 4.23e-01 77.5% 85.3%
3247662 188.1.1.0 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain 0.57 42.0 3.71e-01 79.3% 75.4%
5022856 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.55 42.0 4.04e-01 95.5% 71.0%
3927647 108.1.1.30 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_8 0.50 41.0 3.67e-01 91.0% 90.6%