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protein_ORF85
Euk-VirCyprinid_herpesvirus_1
protein_ORF85__YP_007003748__Cyprinid_herpesvirus_1__317858
Identity
- Accession:
- YP_007003748 ↗
- Protein ID:
- protein_ORF85
- Kingdom:
- euk
Quality
76.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Alloherpesviridae›
Cyvirus›
Cyprinid_herpesvirus_1
TaxID: 317858
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 312-389
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4i6vA02 | 1.10.2020.10 | Mainly Alpha › Orthogonal Bundle › uronate isomerase, domain 2, chain A › uronate isomerase, domain 2, chain A | 0.57 | 46.0 | 4.58e-01 | 100.0% | 85.7% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 43.0 | 3.58e-01 | 83.3% | 68.3% |
| 2w9zA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.56 | 48.0 | 4.13e-01 | 100.0% | 81.2% |
| 3h4cA02 | 1.10.472.110 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › | 0.55 | 47.0 | 4.30e-01 | 100.0% | 75.5% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.54 | 43.0 | 4.15e-01 | 89.7% | 85.9% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.54 | 36.0 | 3.66e-01 | 70.5% | 94.9% |
| 8hbfB01 | 3.90.1520.10 | Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain | 0.53 | 45.0 | 3.49e-01 | 97.4% | 77.9% |
| 3hzsA00 | 1.10.3810.10 | Mainly Alpha › Orthogonal Bundle › Penicillin binding protein transpeptidase fold › Biosynthetic peptidoglycan transglycosylase-like | 0.52 | 42.0 | 3.27e-01 | 97.4% | 86.1% |
| 6wh0A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.52 | 35.0 | 2.90e-01 | 71.8% | 41.4% |
| 1qhhA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 36.0 | 2.94e-01 | 91.0% | 37.2% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3785989 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 56.0 | 5.29e-01 | 92.3% | 80.0% |
| 3782446 | 101.1.6.0 ↗ | alpha arrays › HTH › HTH › TrpR | 0.65 | 55.0 | 5.39e-01 | 92.3% | 88.2% |
| 3391578 | 101.1.1.313 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PF29968 | 0.63 | 53.0 | 4.35e-01 | 93.6% | 80.7% |
| 4960583 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.60 | 41.0 | 3.13e-01 | 71.8% | 38.0% |
| 3443681 | 109.4.1.868 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARMH5 | 0.56 | 44.0 | 3.54e-01 | 88.5% | 68.5% |
| 4022946 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.51 | 44.0 | 3.41e-01 | 100.0% | 88.5% |
| 3214480 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.51 | 45.0 | 2.77e-01 | 98.7% | 15.8% |
| 4056789 | 4198.1.1.2 ↗ | alpha arrays › TerB-like › TerB-like › TerB-like › ThylakoidFormat | 0.51 | 40.0 | 3.09e-01 | 89.7% | 42.0% |
D2
medium
residues 14-53
D3
medium
residues 55-150_174-197
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 43.0 | 5.32e-01 | 88.3% | 100.0% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 44.0 | 4.51e-01 | 91.7% | 65.8% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.70 | 36.0 | 3.67e-01 | 72.5% | 49.6% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 47.0 | 4.72e-01 | 97.5% | 71.1% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 44.0 | 4.46e-01 | 95.0% | 70.0% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 44.0 | 4.28e-01 | 91.7% | 62.5% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 57.0 | 4.39e-01 | 98.3% | 85.2% |
| 4dlqA02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 34.0 | 3.82e-01 | 77.5% | 66.3% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 55.0 | 4.34e-01 | 97.5% | 86.5% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 43.0 | 3.80e-01 | 71.7% | 72.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.61 | 46.0 | 4.45e-01 | 77.5% | 98.5% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.59 | 43.0 | 4.53e-01 | 75.0% | 99.0% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.58 | 35.0 | 3.74e-01 | 92.5% | 68.3% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 44.0 | 4.10e-01 | 80.8% | 78.4% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.57 | 39.0 | 3.69e-01 | 70.8% | 58.9% |
| 1nlxA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.57 | 40.0 | 4.24e-01 | 71.7% | 93.3% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 44.0 | 4.14e-01 | 80.0% | 100.0% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 40.0 | 3.41e-01 | 72.5% | 77.6% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 40.0 | 3.50e-01 | 73.3% | 86.8% |
| 2jpnA00 | 1.20.1280.210 | Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 | 0.56 | 31.0 | 3.75e-01 | 70.8% | 82.3% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.56 | 43.0 | 4.44e-01 | 80.8% | 100.0% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.55 | 41.0 | 3.75e-01 | 79.2% | 76.2% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.54 | 39.0 | 4.13e-01 | 77.5% | 84.9% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 32.0 | 3.36e-01 | 90.8% | 62.8% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.53 | 32.0 | 3.99e-01 | 70.0% | 98.6% |
| 5lnkJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.52 | 37.0 | 3.35e-01 | 74.2% | 74.6% |
| 2hxiB02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 36.0 | 3.50e-01 | 71.7% | 97.0% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.51 | 46.0 | 4.38e-01 | 98.3% | 94.3% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3961790 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.67 | 47.0 | 4.58e-01 | 90.8% | 66.2% |
| 3512735 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.65 | 44.0 | 3.59e-01 | 92.5% | 36.9% |
| 3621676 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 48.0 | 4.69e-01 | 95.8% | 70.8% |
| 3481121 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 45.0 | 4.49e-01 | 98.3% | 71.2% |
| 4927596 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.62 | 39.0 | 3.83e-01 | 98.3% | 57.7% |
| 3939253 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.61 | 44.0 | 3.05e-01 | 74.2% | 35.5% |
| 3799148 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 42.0 | 3.86e-01 | 89.2% | 54.8% |
| 2725659 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 44.0 | 4.30e-01 | 97.5% | 69.5% |
| 3584163 | 904.1.1.0 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain | 0.60 | 41.0 | 3.38e-01 | 90.8% | 40.0% |
| 4947816 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.60 | 42.0 | 4.60e-01 | 72.5% | 100.0% |
| 4981180 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 41.0 | 3.50e-01 | 71.7% | 77.4% |
| 5077016 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.58 | 50.0 | 4.17e-01 | 91.7% | 92.0% |
| 3494756 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.57 | 43.0 | 3.92e-01 | 79.2% | 97.5% |
| 4823418 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 41.0 | 3.29e-01 | 75.0% | 71.5% |
| 3959976 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 42.0 | 3.97e-01 | 79.2% | 92.7% |
| 4954895 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.55 | 39.0 | 4.50e-01 | 95.0% | 97.8% |
| 3345061 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 47.0 | 4.32e-01 | 92.5% | 78.7% |
| 3992787 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 41.0 | 3.65e-01 | 79.2% | 88.0% |
| 3729440 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.53 | 33.0 | 3.15e-01 | 71.7% | 50.0% |
| 3191411 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 42.0 | 4.23e-01 | 89.2% | 84.0% |
| 5048087 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.52 | 36.0 | 3.85e-01 | 72.5% | 95.2% |
| 2329732 | 3718.1.1.1 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT | 0.52 | 44.0 | 4.19e-01 | 92.5% | 95.8% |
| 3172240 | 601.2.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr | 0.52 | 45.0 | 3.85e-01 | 95.8% | 78.5% |
| 4077196 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.51 | 44.0 | 2.93e-01 | 94.2% | 42.5% |
| 3397264 | 4193.1.1.0 ↗ | alpha arrays › RUN domain › RUN domain › RUN domain | 0.51 | 37.0 | 3.33e-01 | 75.8% | 83.5% |
| 3501696 | 101.1.10.6 ↗ | alpha arrays › HTH › HTH › Cyclin-like › RB_A | 0.50 | 39.0 | 2.76e-01 | 81.7% | 55.9% |
| 3922862 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.50 | 43.0 | 4.25e-01 | 93.3% | 98.4% |
D4
medium
residues 151-173_198-303
Domain cluster:
rep: protein_ORF85__YP_007003904__Cyprinid_herpesvirus_2__317878__D186-309