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protein_U4
Euk-VirElephant_endotheliotropic_herpesvirus_4
protein_U4__YP_009179290__Elephant_endotheliotropic_herpesvirus_4__548914
Identity
- Accession:
- YP_009179290 ↗
- Protein ID:
- protein_U4
- Kingdom:
- euk
Quality
69.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephant_endotheliotropic_herpesvirus_4
TaxID: 548914
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 174-266_325-397
Domain cluster:
rep: protein_UL27__YP_004940053__Aotine_betaherpesvirus_1__50290__D178-261_284-374
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.67 | 45.0 | 5.27e-01 | 99.4% | 97.4% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 41.0 | 5.09e-01 | 94.6% | 100.0% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 47.0 | 5.49e-01 | 99.4% | 100.0% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.66 | 36.0 | 4.74e-01 | 92.2% | 100.0% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 42.0 | 5.01e-01 | 100.0% | 100.0% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 42.0 | 4.97e-01 | 100.0% | 97.3% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.64 | 40.0 | 4.25e-01 | 99.4% | 69.9% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.62 | 37.0 | 3.57e-01 | 100.0% | 52.7% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.60 | 34.0 | 2.97e-01 | 100.0% | 35.9% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 29.0 | 4.04e-01 | 84.9% | 100.0% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 40.0 | 3.99e-01 | 99.4% | 66.3% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 47.0 | 4.32e-01 | 84.9% | 97.3% |
| 7eptR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 47.0 | 4.09e-01 | 84.9% | 92.1% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 47.0 | 4.35e-01 | 85.5% | 97.2% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 35.0 | 4.26e-01 | 83.7% | 93.5% |
| 7z0sE02 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.55 | 51.0 | 4.11e-01 | 100.0% | 59.6% |
| 6khjH01 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.55 | 51.0 | 3.92e-01 | 100.0% | 52.0% |
| 8e9gD01 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.55 | 51.0 | 3.79e-01 | 100.0% | 47.3% |
| 7kfuC02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 43.0 | 3.89e-01 | 85.5% | 67.8% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 45.0 | 3.63e-01 | 91.0% | 84.0% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.52 | 36.0 | 4.21e-01 | 100.0% | 98.3% |
| 7rkxR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 41.0 | 3.56e-01 | 84.9% | 95.5% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 45.0 | 4.30e-01 | 98.8% | 80.7% |
| 4p79A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.50 | 47.0 | 4.58e-01 | 100.0% | 98.3% |
| 3no6A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 37.0 | 3.29e-01 | 75.9% | 80.9% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.50 | 41.0 | 3.86e-01 | 98.8% | 72.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3180887 | 174.1.1.9 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF1746 | 0.72 | 48.0 | 5.44e-01 | 100.0% | 86.9% |
| 3973500 | 601.1.2.144 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM | 0.68 | 46.0 | 5.43e-01 | 98.2% | 97.4% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.68 | 50.0 | 5.67e-01 | 100.0% | 97.7% |
| 3661 | 633.10.1.1 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › 23S_rRNA_IVP | 0.67 | 45.0 | 5.29e-01 | 99.4% | 98.2% |
| 4001943 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 46.0 | 5.35e-01 | 100.0% | 99.2% |
| 5001078 | 633.2.1.0 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein | 0.66 | 39.0 | 4.90e-01 | 98.8% | 100.0% |
| 3627650 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.64 | 44.0 | 5.07e-01 | 99.4% | 95.8% |
| 4003102 | 633.5.1.0 ↗ | alpha bundles › Bromodomain-like › LemA-like › LemA-like | 0.63 | 41.0 | 4.39e-01 | 100.0% | 74.5% |
| 1268318 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.62 | 29.0 | 3.43e-01 | 100.0% | 62.7% |
| 3815122 | 604.12.1.68 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 | 0.61 | 33.0 | 3.28e-01 | 83.7% | 48.3% |
| 3731115 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 42.0 | 4.31e-01 | 100.0% | 74.4% |
| 3398008 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.59 | 47.0 | 3.95e-01 | 84.9% | 92.3% |
| 3316418 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.58 | 47.0 | 5.01e-01 | 100.0% | 96.6% |
| 3462341 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 42.0 | 3.47e-01 | 100.0% | 42.7% |
| 3630260 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.56 | 47.0 | 3.80e-01 | 89.2% | 85.7% |
| 3347110 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.56 | 44.0 | 3.88e-01 | 82.5% | 71.6% |
| 3606357 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.54 | 30.0 | 3.09e-01 | 83.7% | 53.3% |
| 3847759 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.53 | 49.0 | 4.47e-01 | 100.0% | 74.5% |
| 3213593 | 3615.1.1.4 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Tmem26 | 0.53 | 36.0 | 3.10e-01 | 98.8% | 42.6% |
| 4295410 | 633.13.1.1 ↗ | alpha bundles › Bromodomain-like › DsbB-like › DsbB-like › DsbB | 0.53 | 48.0 | 4.90e-01 | 100.0% | 98.8% |
| 4541777 | 3592.1.1.1 ↗ | alpha bundles › Oncogenic effector CagA N-terminal domain › Oncogenic effector CagA N-terminal domain › Oncogenic effector CagA N-terminal domain › CagA_N | 0.52 | 46.0 | 4.34e-01 | 98.2% | 79.0% |
| 3795762 | 3567.1.1.9 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › CECR6_TMEM121 | 0.52 | 40.0 | 3.30e-01 | 100.0% | 45.5% |
| 3926513 | 5069.1.1.38 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 | 0.52 | 41.0 | 3.68e-01 | 84.9% | 85.0% |
| 3214290 | 389.1.3.0 ↗ | few secondary structure elements › EGF-like › EGF-related › TNF receptor-like | 0.51 | 47.0 | 4.74e-01 | 100.0% | 98.8% |
| 3467501 | 602.1.1.0 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like | 0.50 | 41.0 | 3.61e-01 | 85.5% | 86.3% |
D2
medium
residues 73-169