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protein_UL27
Euk-VirCercopithecine_betaherpesvirus_5
protein_UL27__YP_004936004__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936004 ↗
- Protein ID:
- protein_UL27
- Kingdom:
- euk
Quality
83.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 180-262_281-374
Domain cluster:
rep: protein_UL27__YP_004940053__Aotine_betaherpesvirus_1__50290__D178-261_284-374
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05999.17 best | Herpes_U5 | 100.6 | 1.40e-28 | 53.1% | 19.5% |
| PF05999.17 | Herpes_U5 | 84.6 | 9.80e-24 | 49.1% | 17.6% |
D2
medium
residues 11-55_75-116_463-502_539-570
Domain cluster:
rep: protein_UL27__YP_002608241__Human_herpesvirus_5__10359__D30-84_99-149_492-533
D3
medium
residues 117-179
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05999.17 best | Herpes_U5 | 38.0 | 1.40e-09 | 63.5% | 7.2% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6t4hA03 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.65 | 46.0 | 3.41e-01 | 76.2% | 28.5% |
| 1cbyA00 | 3.40.198.10 | Alpha Beta › 3-Layer(aba) Sandwich › Delta-endotoxin CytB › Delta-endotoxin CytB-like | 0.65 | 49.0 | 3.38e-01 | 82.5% | 42.3% |
| 4linD01 | 1.20.5.340 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 44.0 | 3.38e-01 | 92.1% | 31.2% |
| 4nv1E01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.64 | 46.0 | 3.26e-01 | 76.2% | 44.6% |
| 5vyqA01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.63 | 46.0 | 3.32e-01 | 77.8% | 44.6% |
| 3q23A03 | 6.10.140.1360 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 51.0 | 4.92e-01 | 92.1% | 94.4% |
| 2mjfB00 | 1.20.1440.260 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.60 | 44.0 | 3.89e-01 | 82.5% | 52.6% |
| 4n1yB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.60 | 50.0 | 3.51e-01 | 96.8% | 82.4% |
| 1d8cA02 | 2.170.170.11 | Mainly Beta › Beta Complex › Malate synthase G - maily-beta sub-domain › Malate synthase G - maily-beta sub-domain | 0.60 | 44.0 | 3.44e-01 | 76.2% | 77.3% |
| 1na6B02 | 3.40.91.80 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.58 | 50.0 | 3.51e-01 | 100.0% | 86.9% |
| 7miqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 47.0 | 3.92e-01 | 88.9% | 51.8% |
| 2wd6A00 | 2.60.530.10 | Mainly Beta › Sandwich › Major cell-surface adhesin PAc › Major cell-surface adhesin PAc | 0.58 | 46.0 | 3.02e-01 | 90.5% | 35.8% |
| 2dkwA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.57 | 48.0 | 3.91e-01 | 100.0% | 77.1% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 47.0 | 4.29e-01 | 100.0% | 69.0% |
| 7r8bB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.04e-01 | 95.2% | 37.4% |
| 4k3bA04 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.50 | 43.0 | 4.02e-01 | 98.4% | 88.5% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3743093 | 524.1.1.1 ↗ | alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC | 0.75 | 52.0 | 3.97e-01 | 77.8% | 31.7% |
| 3398104 | 108.1.1.97 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7 | 0.68 | 56.0 | 4.72e-01 | 90.5% | 70.5% |
| 3344715 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 61.0 | 4.06e-01 | 100.0% | 38.7% |
| 4170537 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.66 | 54.0 | 4.23e-01 | 88.9% | 49.2% |
| 4028163 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.66 | 53.0 | 3.93e-01 | 87.3% | 38.7% |
| 4566653 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.63 | 54.0 | 4.07e-01 | 90.5% | 65.0% |
| 4197827 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.62 | 55.0 | 4.13e-01 | 95.2% | 62.2% |
| 3500715 | 633.24.1.2 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 | 0.61 | 54.0 | 5.01e-01 | 100.0% | 88.7% |
| 4205724 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.61 | 53.0 | 3.90e-01 | 95.2% | 54.2% |
| 3425084 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 46.0 | 4.11e-01 | 100.0% | 58.9% |
| 3592315 | 7583.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins | 0.55 | 45.0 | 2.92e-01 | 96.8% | 27.5% |
| 4015072 | 4096.1.1.0 ↗ | a+b two layers › NAP-like › NAP-like › NAP-like | 0.55 | 39.0 | 2.97e-01 | 76.2% | 32.4% |
| 3278587 | 191.1.1.1 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_1 | 0.53 | 44.0 | 3.38e-01 | 96.8% | 41.3% |
| 3650912 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.51 | 37.0 | 2.54e-01 | 81.0% | 89.8% |
D4
medium
residues 380-462_503-538
Domain cluster:
rep: GP27__YP_007417799__Caviid_betaherpesvirus_2__33706__D389-473_516-548
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05999.17 best | Herpes_U5 | 84.7 | 9.60e-24 | 74.0% | 17.4% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 39.0 | 4.79e-01 | 79.8% | 77.8% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.71 | 39.0 | 5.11e-01 | 79.8% | 100.0% |
| 7t7kA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.69 | 49.0 | 4.92e-01 | 80.7% | 72.9% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 50.0 | 5.25e-01 | 75.6% | 99.1% |
| 1egdA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 50.0 | 4.74e-01 | 75.6% | 100.0% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 49.0 | 5.08e-01 | 74.8% | 95.5% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 38.0 | 4.78e-01 | 79.8% | 98.5% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 36.0 | 4.56e-01 | 79.8% | 100.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 35.0 | 4.45e-01 | 79.8% | 93.8% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 36.0 | 3.90e-01 | 82.4% | 66.7% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 41.0 | 4.77e-01 | 74.8% | 97.7% |
| 2yn7A00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.59 | 42.0 | 3.44e-01 | 89.9% | 40.7% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.58 | 44.0 | 4.55e-01 | 79.0% | 99.1% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 43.0 | 4.77e-01 | 79.8% | 97.9% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3722421 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.80 | 43.0 | 4.04e-01 | 79.8% | 45.7% |
| 3969893 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.80 | 42.0 | 5.76e-01 | 79.8% | 96.9% |
| 3385717 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 44.0 | 3.82e-01 | 82.4% | 41.2% |
| 3600361 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.75 | 43.0 | 4.80e-01 | 79.8% | 71.6% |
| 3970792 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.73 | 54.0 | 5.46e-01 | 76.5% | 98.3% |
| 3593736 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.72 | 42.0 | 4.63e-01 | 82.4% | 70.0% |
| 5078048 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.70 | 41.0 | 5.07e-01 | 82.4% | 93.3% |
| 3932809 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.70 | 51.0 | 4.71e-01 | 75.6% | 94.0% |
| 4012137 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.68 | 50.0 | 4.81e-01 | 75.6% | 94.8% |
| 3970810 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.67 | 37.0 | 4.40e-01 | 79.8% | 80.0% |
| 4941676 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 42.0 | 3.62e-01 | 82.4% | 44.6% |
| 3626316 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 53.0 | 5.18e-01 | 86.6% | 96.9% |
| 3230740 | 5001.1.1.35 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx | 0.64 | 48.0 | 3.64e-01 | 79.0% | 82.5% |
| 3225319 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 49.0 | 4.99e-01 | 80.7% | 100.0% |
| 4029481 | 7525.1.1.2 ↗ | a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_2 | 0.63 | 58.0 | 3.82e-01 | 97.5% | 40.7% |
| 3175481 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.62 | 41.0 | 3.54e-01 | 87.4% | 43.9% |
| 3407103 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.61 | 46.0 | 4.37e-01 | 79.0% | 90.7% |
| 3560229 | 3291.1.1.230 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH | 0.61 | 43.0 | 4.08e-01 | 79.8% | 62.1% |
| 5070606 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.60 | 45.0 | 4.30e-01 | 78.2% | 92.6% |
| 3839889 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.55 | 44.0 | 4.06e-01 | 81.5% | 89.0% |
| 4937014 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 43.0 | 2.96e-01 | 86.6% | 36.6% |