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protein_UL27
Euk-VirHuman_betaherpesvirus_7
protein_UL27__YP_073748__Human_betaherpesvirus_7__10372
Identity
- Accession:
- YP_073748 ↗
- Protein ID:
- protein_UL27
- Kingdom:
- euk
Quality
76.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_7
TaxID: 10372
Cluster
View cluster (26 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 143-329
Domain cluster:
rep: protein_UL27__YP_004940053__Aotine_betaherpesvirus_1__50290__D178-261_284-374
D2
medium
residues 46-111_424-456
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3tl4X02 | 1.10.10.2420 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 25.0 | 2.93e-01 | 80.8% | 61.1% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3678963 | 148.1.3.205 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_At3g28540 | 0.57 | 31.0 | 3.29e-01 | 88.9% | 57.8% |
| 5024159 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.54 | 40.0 | 4.06e-01 | 78.8% | 99.0% |
| 3643035 | 193.1.1.0 ↗ | alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like | 0.52 | 42.0 | 3.16e-01 | 89.9% | 41.5% |
| 3699983 | 108.1.1.29 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_7 | 0.51 | 39.0 | 4.12e-01 | 92.9% | 91.1% |
| 3758843 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.50 | 36.0 | 3.76e-01 | 80.8% | 85.2% |
D3
medium
residues 112-135_333-423
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.79 | 61.0 | 4.87e-01 | 80.9% | 67.3% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.78 | 61.0 | 5.87e-01 | 81.7% | 95.3% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.77 | 59.0 | 5.95e-01 | 80.0% | 93.8% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.77 | 58.0 | 5.59e-01 | 79.1% | 93.0% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.76 | 57.0 | 5.77e-01 | 77.4% | 93.8% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.73 | 61.0 | 5.86e-01 | 87.8% | 94.5% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.73 | 55.0 | 5.76e-01 | 79.1% | 100.0% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.73 | 57.0 | 5.52e-01 | 83.5% | 95.3% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 55.0 | 5.48e-01 | 80.9% | 91.7% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.72 | 50.0 | 5.76e-01 | 75.7% | 100.0% |
| 5ziyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.72 | 56.0 | 4.68e-01 | 82.6% | 73.2% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.71 | 54.0 | 5.39e-01 | 80.9% | 84.7% |
| 1aueB00 | 1.20.120.150 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain | 0.69 | 51.0 | 5.59e-01 | 78.3% | 100.0% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.69 | 52.0 | 5.26e-01 | 80.0% | 99.1% |
| 3thxB03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.68 | 53.0 | 4.56e-01 | 83.5% | 78.8% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.68 | 51.0 | 5.07e-01 | 79.1% | 95.8% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.66 | 51.0 | 4.99e-01 | 80.9% | 99.2% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.66 | 47.0 | 4.46e-01 | 73.9% | 76.5% |
| 2qw6D00 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.65 | 45.0 | 5.10e-01 | 76.5% | 95.3% |
| 1cm5A00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.65 | 45.0 | 2.72e-01 | 71.3% | 66.1% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.65 | 47.0 | 4.22e-01 | 74.8% | 76.3% |
| 4l68A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.64 | 50.0 | 4.19e-01 | 84.3% | 86.7% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.59 | 45.0 | 3.53e-01 | 80.0% | 63.1% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.56 | 44.0 | 4.05e-01 | 82.6% | 64.9% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.53 | 34.0 | 3.77e-01 | 70.4% | 80.4% |
| 3r9bA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.53 | 47.0 | 3.27e-01 | 100.0% | 57.8% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 39.0 | 2.79e-01 | 80.0% | 90.8% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.55e-01 | 78.3% | 77.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.51 | 38.0 | 3.13e-01 | 80.0% | 93.6% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3603712 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.79 | 57.0 | 6.06e-01 | 74.8% | 100.0% |
| 5013258 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.77 | 60.0 | 5.85e-01 | 81.7% | 96.0% |
| 5068160 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.76 | 57.0 | 5.78e-01 | 79.1% | 80.0% |
| 3233893 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.74 | 57.0 | 5.85e-01 | 81.7% | 96.4% |
| 2466822 | 601.2.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr | 0.72 | 56.0 | 4.62e-01 | 82.6% | 50.5% |
| 3950589 | 601.18.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › DUF4395 | 0.70 | 52.0 | 5.57e-01 | 79.1% | 95.0% |
| 3283506 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.67 | 50.0 | 5.24e-01 | 80.9% | 99.0% |
| 3386718 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 51.0 | 4.57e-01 | 80.9% | 69.2% |
| 4971764 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.64 | 51.0 | 4.20e-01 | 85.2% | 61.5% |
| 5020750 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.63 | 49.0 | 4.02e-01 | 83.5% | 87.0% |
| 3754435 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.59 | 45.0 | 3.58e-01 | 80.9% | 55.0% |
| 4460786 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 46.0 | 3.89e-01 | 81.7% | 56.8% |
| 4209793 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.57 | 41.0 | 3.44e-01 | 74.8% | 71.6% |
| 3250955 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.54 | 41.0 | 3.03e-01 | 80.0% | 46.0% |
| 4029359 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 37.0 | 3.57e-01 | 71.3% | 79.1% |
| 3676953 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.53 | 38.0 | 2.39e-01 | 74.8% | 26.4% |
| 3638803 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.51 | 38.0 | 3.45e-01 | 79.1% | 58.7% |
| 4033735 | 5048.1.1.2 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › Form_Nir_trans | 0.51 | 39.0 | 3.11e-01 | 84.3% | 73.1% |