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protein_US26

Euk-Vir

Saimiriine_betaherpesvirus_4

protein_US26__YP_004940303__Saimiriine_betaherpesvirus_4__1535247

Identity

Accession:
YP_004940303 ↗
Protein ID:
protein_US26
Kingdom:
euk

Quality

76.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Saimiriine_betaherpesvirus_4

TaxID: 1535247

Cluster

View cluster (59 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 186-324
PDB
Domain cluster: rep: US22_family_homolog__YP_214055__Murid_betaherpesvirus_1__10366__D433-537
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02393.22 best US22 66.2 4.20e-18 93.5% 97.6%
D2 high residues 450-494
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bujE03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.62 52.0 3.31e-01 97.8% 19.3%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.61 41.0 3.19e-01 84.4% 31.4%
2yveB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 52.0 3.55e-01 100.0% 30.8%
3gkuA03 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.60 49.0 4.37e-01 100.0% 63.4%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.59 40.0 3.52e-01 95.6% 47.8%
2bskB00 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.59 41.0 3.58e-01 84.4% 50.8%
2c35A00 1.20.1250.40 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit 0.58 45.0 3.31e-01 86.7% 44.5%
8amqA02 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.58 47.0 2.85e-01 100.0% 68.0%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.58 42.0 3.22e-01 80.0% 30.8%
2r8wA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 47.0 2.87e-01 93.3% 18.2%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 41.0 3.96e-01 80.0% 66.7%
2l82A00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 45.0 3.17e-01 97.8% 25.9%
3dz1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 45.0 2.80e-01 91.1% 14.0%
2e5yA02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.57 36.0 3.68e-01 97.8% 66.7%
3if4A02 1.20.5.1210 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Integron cassette protein helical domain 0.57 44.0 4.41e-01 86.7% 95.7%
3s5nA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 49.0 3.00e-01 100.0% 15.3%
1wazA00 1.10.287.910 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › bacterial mercury transporter, merf 0.56 40.0 4.06e-01 80.0% 78.3%
1jb0K00 1.20.860.20 Mainly Alpha › Up-down Bundle › Alpha-t-alpha › Photosystem I PsaK, reaction centre 0.56 38.0 3.84e-01 75.6% 71.7%
2w4sA00 1.10.10.1440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PHAX RNA-binding domain 0.55 41.0 3.31e-01 80.0% 47.7%
1xqrA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.55 45.0 2.83e-01 95.6% 34.8%
1eniA00 1.10.440.10 Mainly Alpha › Orthogonal Bundle › Endonuclease V › T4 endonuclease V 0.55 45.0 3.36e-01 100.0% 53.3%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 41.0 2.68e-01 86.7% 16.5%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 41.0 3.54e-01 86.7% 50.7%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 43.0 3.66e-01 86.7% 57.5%
2jnsA01 1.20.1270.220 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 40.0 3.30e-01 80.0% 58.0%
1wdhA02 1.10.720.60 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.54 42.0 3.15e-01 82.2% 41.2%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.54 40.0 3.33e-01 80.0% 70.7%
4n21E00 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 44.0 3.19e-01 88.9% 62.0%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.54 41.0 3.73e-01 86.7% 64.1%
2kseA00 1.20.5.1040 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Sensor protein qsec. 0.54 40.0 3.39e-01 82.2% 68.8%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 43.0 3.27e-01 91.1% 70.5%
1bccH00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.53 41.0 3.63e-01 93.3% 57.6%
3eeeA00 3.90.1520.10 Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain 0.53 38.0 2.62e-01 88.9% 19.7%
7lvlA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 44.0 2.76e-01 100.0% 15.6%
1r5aA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 42.0 3.19e-01 100.0% 35.3%
4cclA02 3.40.366.30 Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › 50S ribosomal protein L16 arginine hydroxylase; Chain A, Domain 2 0.53 43.0 2.98e-01 95.6% 28.0%
3lyuA01 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.52 41.0 3.18e-01 91.1% 35.7%
3eb2A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 42.0 2.67e-01 100.0% 15.3%
3kdqA00 6.10.320.10 Special › Helix non-globular › Ferritin › 0.52 45.0 3.02e-01 97.8% 27.6%
6cgaC02 1.20.58.860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 40.0 3.36e-01 84.4% 66.7%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.50 37.0 3.07e-01 86.7% 68.4%
2r6hA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.50 41.0 3.03e-01 95.6% 34.7%
1vw4801 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.50 34.0 2.97e-01 73.3% 86.3%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3932729 630.1.1.0 ↗ a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.72 45.0 3.23e-01 93.3% 23.2%
3223091 213.1.1.0 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.66 55.0 3.98e-01 100.0% 32.6%
3782437 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.61 44.0 3.38e-01 75.6% 77.0%
3896924 320.4.1.5 ↗ a+b two layers › R3H domain-like › PUB domain › PUB domain › Gasdermin_C 0.60 52.0 3.39e-01 100.0% 25.4%
4026646 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.60 43.0 3.53e-01 86.7% 41.2%
3663201 320.1.1.13 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › BMT5-like 0.59 51.0 4.45e-01 100.0% 65.7%
4771678 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.58 46.0 3.43e-01 100.0% 31.1%
4023774 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.58 44.0 2.75e-01 93.3% 14.8%
3404343 192.29.1.1 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.57 41.0 3.36e-01 77.8% 54.4%
3858699 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.56 39.0 2.97e-01 73.3% 70.0%
3951183 573.1.1.0 ↗ alpha duplicates or obligate multimers › Soluble domain of poliovirus core protein 3a › Soluble domain of poliovirus core protein 3a › Soluble domain of poliovirus core protein 3a 0.56 40.0 4.17e-01 84.4% 87.5%
3891023 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.56 48.0 3.22e-01 97.8% 53.3%
3542362 389.1.1.127 ↗ few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › ANATO 0.56 45.0 4.44e-01 97.8% 84.0%
3179945 616.1.1.23 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › PF28719 0.56 45.0 3.47e-01 88.9% 48.0%
56798 150.7.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE 0.56 41.0 3.46e-01 80.0% 76.3%
3182634 3826.1.1.0 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.55 43.0 3.41e-01 86.7% 42.2%
3581368 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 44.0 3.00e-01 86.7% 55.3%
3648942 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.54 45.0 3.23e-01 100.0% 76.8%
3364683 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.54 43.0 3.42e-01 93.3% 44.4%
3656598 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.53 42.0 3.10e-01 91.1% 93.1%
5032177 1079.1.1.8 ↗ alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.53 45.0 2.96e-01 97.8% 54.8%
3634447 4207.1.2.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.53 45.0 3.52e-01 100.0% 61.0%
3230399 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 47.0 3.23e-01 100.0% 42.0%
3642338 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.53 42.0 3.58e-01 88.9% 81.3%
3933875 109.4.1.298 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VPS15-like_hel 0.52 42.0 2.39e-01 100.0% 7.7%
3608382 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.52 45.0 2.98e-01 97.8% 23.1%
3731383 192.7.1.0 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.52 40.0 3.17e-01 86.7% 62.0%
3827291 184.1.1.0 ↗ alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N 0.51 40.0 3.58e-01 97.8% 77.3%
3605561 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 44.0 3.06e-01 100.0% 98.8%
3586169 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 45.0 3.18e-01 100.0% 51.4%
3217811 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 45.0 3.14e-01 100.0% 95.3%
4948599 192.2.1.2 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.50 43.0 3.43e-01 95.6% 53.3%
4972788 601.2.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.50 42.0 3.27e-01 100.0% 57.3%
3990854 192.7.1.0 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.50 40.0 3.16e-01 86.7% 71.1%
D3 medium residues 1-180
PDB
Domain cluster: rep: protein_U95__YP_073826__Human_betaherpesvirus_7__10372__D619-769
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02393.22 best US22 53.4 3.80e-14 81.1% 94.3%